Motif ID: NFATC1..3.p2

Z-value: 1.858


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC1chr18_+_75256931-0.562.9e-02Click!
NFATC2chr20_-_49592444-0.421.2e-01Click!
NFATC3chr16_+_66676833-0.352.0e-01Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_116434364 4.853 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr10_-_116434102 3.652 ABLIM1
actin binding LIM protein 1
chr11_-_85115105 3.077 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr18_-_51219880 3.076 TCF4
transcription factor 4
chr8_-_13416554 2.865 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr18_+_64616296 2.802 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr1_+_100957883 2.666 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr9_+_676640 2.592


chr3_-_150533948 2.193 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr12_+_13240868 2.137 NM_001423
EMP1
epithelial membrane protein 1
chr9_-_36266930 2.131 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr12_-_90097384 2.116 NM_133503
DCN
decorin
chr17_+_44643067 2.111 ABI3
ABI family, member 3
chr8_-_93144039 2.107


chr3_+_69895651 2.086 NM_006722
MITF
microphthalmia-associated transcription factor
chr6_-_112186977 2.075 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr12_+_13240983 2.042 EMP1
epithelial membrane protein 1
chr12_-_50871953 2.037 NM_001081492
NM_182507
KRT80

keratin 80

chr1_+_157246305 1.964 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr15_-_40537002 1.938 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr3_+_120799411 1.936 NM_015900
PLA1A
phospholipase A1 member A
chr12_+_13240987 1.900 EMP1
epithelial membrane protein 1
chr12_-_54392328 1.898 NM_001144997
ITGA7
integrin, alpha 7
chr9_+_35528628 1.865 NM_001135999
RUSC2
RUN and SH3 domain containing 2
chr1_+_161305558 1.851 NM_001113381
RGS4
regulator of G-protein signaling 4
chr9_+_35528890 1.848 RUSC2
RUN and SH3 domain containing 2
chr1_-_167865973 1.817 NM_003005
SELP
selectin P (granule membrane protein 140kDa, antigen CD62)
chr2_-_202271598 1.811 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr1_+_78888064 1.765 NM_006417
IFI44
interferon-induced protein 44
chr15_+_37330176 1.744 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr7_-_100668820 1.735 NM_001185080
CLDN15
claudin 15
chr3_-_124893875 1.730 MYLK
myosin light chain kinase
chr10_-_31328426 1.728 NM_001143769
ZNF438
zinc finger protein 438
chr5_+_55182963 1.676 NM_139017
IL31RA
interleukin 31 receptor A
chr8_+_42671718 1.666 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr12_+_118100977 1.653 NM_014365
HSPB8
heat shock 22kDa protein 8
chr18_+_7936885 1.635 PTPRM
protein tyrosine phosphatase, receptor type, M
chrX_+_2680092 1.628 NM_001141919
NM_001141920
NM_175569
XGPY2
XG


Xg pseudogene, Y-linked 2
Xg blood group


chr2_+_33514896 1.619 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr20_-_1298493 1.548 FKBP1A
FK506 binding protein 1A, 12kDa
chr8_-_93144366 1.544 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_102380156 1.498 NM_001018116
MURC
muscle-related coiled-coil protein
chr10_+_69539255 1.493 NM_032578
MYPN
myopalladin
chr3_+_45042754 1.441 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr17_-_44642934 1.420 NM_001198754
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_-_189363075 1.418 NM_052952
DIRC1
disrupted in renal carcinoma 1
chr13_-_98757634 1.395 NM_004951
GPR183
G protein-coupled receptor 183
chr6_+_39868770 1.388 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr9_-_15240113 1.377 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr1_-_171286634 1.374 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr4_-_152366970 1.354 NM_001009555
NM_001128923
SH3D19

SH3 domain containing 19

chr2_-_134042500 1.331 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr7_+_18502342 1.262 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr14_+_99309688 1.257 EML1
echinoderm microtubule associated protein like 1
chr3_-_46693902 1.254 NM_182775
ALS2CL
ALS2 C-terminal like
chr8_+_70567581 1.239 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr6_+_42896771 1.226 NM_015349
KIAA0240
KIAA0240
chr4_+_109033868 1.218 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr8_+_70567634 1.209 SULF1
sulfatase 1
chr1_-_79244948 1.208 NM_022159
ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr2_-_192420168 1.203 NM_004657
SDPR
serum deprivation response
chr12_-_15706340 1.201 EPS8
epidermal growth factor receptor pathway substrate 8
chr4_+_2853434 1.192 ADD1
adducin 1 (alpha)
chr4_+_169654742 1.191 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr1_-_149047329 1.190 NM_000396
CTSK
cathepsin K
chr12_+_12829807 1.186 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr16_+_65938753 1.179 NM_001161575
LRRC36
leucine rich repeat containing 36
chr12_-_14929991 1.173 NM_000900
NM_001190839
MGP

matrix Gla protein

chr8_-_18585721 1.161 PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_145296313 1.133 NM_152550
SH3RF2
SH3 domain containing ring finger 2
chr4_+_146820805 1.119 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr17_+_44642587 1.116 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr11_-_71458739 1.108 NUMA1
nuclear mitotic apparatus protein 1
chr3_+_69216747 1.107 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr17_-_26672757 1.107 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr4_+_95595419 1.101 PDLIM5
PDZ and LIM domain 5
chr11_-_102219450 1.095 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr5_+_34720368 1.073 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr17_+_7732759 1.062 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr2_-_188021117 1.061 NM_005795
CALCRL
calcitonin receptor-like
chrX_-_19598912 1.053 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_154397975 1.050 TRIM2
tripartite motif containing 2
chr7_+_18501876 1.034 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr3_-_113842652 1.034 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chrX_+_135079120 1.034 NM_001159704
FHL1
four and a half LIM domains 1
chr13_+_100902942 1.034 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr9_+_88953378 1.030 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr3_-_158695832 1.023 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr1_+_39694849 1.023 MACF1
microtubule-actin crosslinking factor 1
chr3_-_113841448 1.022 CCDC80
coiled-coil domain containing 80
chr3_+_161040439 1.020 SCHIP1
schwannomin interacting protein 1
chr8_-_82557956 1.017 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr6_-_110843432 1.005 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr5_-_54317102 1.003 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr21_-_26867138 0.996 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr5_-_132300702 0.991


chr16_+_83349816 0.985 USP10
ubiquitin specific peptidase 10
chr20_+_42644633 0.985 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr5_+_38481392 0.982 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr12_+_32578513 0.979 FGD4
FYVE, RhoGEF and PH domain containing 4
chr17_+_29606408 0.977 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr2_+_36777406 0.975 VIT
vitrin
chr2_-_133145539 0.949 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr8_-_82606104 0.947 NM_001105281
FABP12
fatty acid binding protein 12
chr7_-_41709191 0.946 NM_002192
INHBA
inhibin, beta A
chr3_-_113842553 0.945 CCDC80
coiled-coil domain containing 80
chr4_-_177427252 0.938 NM_080874
ASB5
ankyrin repeat and SOCS box containing 5
chr8_-_6407882 0.935 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr16_+_65868913 0.934 NM_015432
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chrX_-_138742050 0.927 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr2_+_110013297 0.922 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr6_-_47030492 0.922 NM_015234
GPR116
G protein-coupled receptor 116
chr5_+_176494690 0.915 NSD1
nuclear receptor binding SET domain protein 1
chr2_-_231697999 0.914 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr13_-_32822759 0.910 STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_+_88187215 0.909 AFF1
AF4/FMR2 family, member 1
chr9_-_90983195 0.906 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr7_-_27133163 0.905 NM_153631
HOXA3
homeobox A3
chr17_-_36469869 0.898 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr5_-_32424352 0.894 ZFR
zinc finger RNA binding protein
chr5_-_58607673 0.887 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_-_152431175 0.884 NM_152263
TPM3
tropomyosin 3
chr9_-_112139908 0.865 NM_001003936
TXNDC8
thioredoxin domain containing 8 (spermatozoa)
chr4_-_152368492 0.860 SH3D19
SH3 domain containing 19
chrX_-_10504852 0.860 NM_001193277
MID1
midline 1 (Opitz/BBB syndrome)
chr17_-_36451189 0.858 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr16_+_4842077 0.858 NM_016936
UBN1
ubinuclein 1
chr3_+_103029523 0.857 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr9_-_74735669 0.850 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr2_-_227952249 0.848 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr14_+_77296925 0.835 NM_001173978
NM_174943
C14orf178

chromosome 14 open reading frame 178

chr2_+_69055208 0.829 NM_019617
GKN1
gastrokine 1
chr3_+_189425886 0.822 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr8_-_37847095 0.818 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr2_-_37727472 0.818 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr2_-_110665188 0.817 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr2_-_183095308 0.815 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr11_+_5597749 0.814 NM_001003827
TRIM34
tripartite motif containing 34
chr11_-_68537243 0.811 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr2_+_189547377 0.808 COL3A1
collagen, type III, alpha 1
chr4_-_71751205 0.806 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr21_-_35174742 0.798 RUNX1
runt-related transcription factor 1
chr1_+_17817397 0.796 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr22_-_34566210 0.793 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_+_36777336 0.789 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr1_-_68470585 0.786 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr6_-_169395847 0.785 THBS2
thrombospondin 2
chr11_-_117200618 0.783 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr18_-_44723116 0.783 NM_001190823
SMAD7
SMAD family member 7
chr22_+_31526801 0.778 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr6_-_2785682 0.773 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr15_+_72253077 0.773 NM_005545
ISLR
immunoglobulin superfamily containing leucine-rich repeat
chr1_-_154215558 0.771 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr15_+_79304694 0.771 NM_172217
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr3_+_190147633 0.769 TPRG1
tumor protein p63 regulated 1
chr1_-_203657803 0.763 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr2_+_108637698 0.758 NM_001193485
LIMS1
LIM and senescent cell antigen-like domains 1
chr8_+_134272463 0.754 NM_003882
NM_080838
WISP1

WNT1 inducible signaling pathway protein 1

chrX_-_77801480 0.752 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr8_-_102034777 0.750 NM_003406
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr8_+_32698892 0.749 NM_001159996
NRG1
neuregulin 1
chr7_-_15568099 0.748 NM_001004320
AGMO
alkylglycerol monooxygenase
chr10_-_29963906 0.744 NM_021738
SVIL
supervillin
chr3_+_158743852 0.743 NM_001099777
NM_001130001
NM_001130002
C3orf55


chromosome 3 open reading frame 55


chr16_+_24696069 0.736 TNRC6A
trinucleotide repeat containing 6A
chr1_+_54786394 0.735 NM_015547
NM_147161
ACOT11

acyl-CoA thioesterase 11

chr21_+_25856311 0.719 MIR155HG
MIR155 host gene (non-protein coding)
chr15_+_75500284 0.715 NM_018200
HMG20A
high-mobility group 20A
chr2_+_170074457 0.715 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chrX_+_122821217 0.712 NM_001167
XIAP
X-linked inhibitor of apoptosis
chr9_-_15500209 0.710 NM_021144
PSIP1
PC4 and SFRS1 interacting protein 1
chr6_+_106653429 0.709 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr4_+_74825138 0.708 NM_000584
IL8
interleukin 8
chr4_-_186934059 0.705 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr13_-_101852028 0.704 NM_175929
FGF14
fibroblast growth factor 14
chr4_+_86968069 0.704 ARHGAP24
Rho GTPase activating protein 24
chr5_-_59100091 0.703 PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_5500544 0.702 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr1_-_45868775 0.701 GPBP1L1
GC-rich promoter binding protein 1-like 1
chr6_-_134680888 0.701 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chrX_-_43717864 0.700 NM_000266
NDP
Norrie disease (pseudoglioma)
chr5_+_147628567 0.700 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr3_-_113841200 0.699 CCDC80
coiled-coil domain containing 80
chr6_+_10663934 0.696 NM_001491
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr14_-_22693333 0.696 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter, L-type), member 8
chr10_-_90702490 0.695 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr9_+_70046658 0.693 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr9_-_72673753 0.692 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr1_+_98899734 0.692 NM_015976
NM_152238
SNX7

sorting nexin 7

chr5_-_34078991 0.690 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr11_-_85074848 0.690 NM_152723
CCDC89
coiled-coil domain containing 89
chr7_+_28305464 0.686 NM_182899
CREB5
cAMP responsive element binding protein 5
chr16_+_68516401 0.686 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr1_+_159435728 0.685 NM_004550
NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr4_-_38482805 0.684 NM_003263
TLR1
toll-like receptor 1
chr6_+_17210467 0.684 NM_001190766
FLJ23152
hypothetical protein LOC401236
chr6_-_33862690 0.682 NM_001143944
LEMD2
LEM domain containing 2
chr12_-_55404530 0.679 NACA
nascent polypeptide-associated complex alpha subunit
chr22_-_34566367 0.677 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr4_-_38534802 0.677 NM_006068
TLR6
toll-like receptor 6

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.