Motif ID: NFE2.p2

Z-value: 1.794


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2chr12_-_52980914-0.224.4e-01Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_221955876 14.113 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr12_-_68369322 8.414 NM_152439
BEST3
bestrophin 3
chr21_+_29439768 4.895 C21orf7
chromosome 21 open reading frame 7
chr5_+_150000394 4.147 NM_001109974
NM_007286
SYNPO

synaptopodin

chr5_-_141041982 4.094 NM_022481
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_+_148747208 3.678 ECM1
extracellular matrix protein 1
chr1_+_148747110 3.389 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr9_+_676640 3.388


chr1_+_153232685 3.367 NM_018655
LENEP
lens epithelial protein
chr5_-_141041933 3.365 ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr1_-_93030538 3.352 NM_005665
EVI5
ecotropic viral integration site 5
chr11_-_102174102 3.279 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr11_-_102174032 3.198 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr17_+_18566060 3.183 NM_001037330
TRIM16L
tripartite motif containing 16-like
chr21_-_35343065 2.848 RUNX1
runt-related transcription factor 1
chr13_+_51334117 2.804 NM_031290
CCDC70
coiled-coil domain containing 70
chr2_+_169634330 2.772 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr6_-_28429950 2.759 NM_145909
ZNF323
zinc finger protein 323
chr19_+_43572679 2.703 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr2_-_73170290 2.646 RAB11FIP5
RAB11 family interacting protein 5 (class I)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.59 2.77e-02 GO:0051246 regulation of protein metabolic process
1.30 2.94e-02 GO:0007165 signal transduction
1.20 2.75e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
6.79 3.61e-03 GO:0001533 cornified envelope
3.68 1.39e-02 GO:0000502 proteasome complex
1.67 4.14e-03 GO:0005626 insoluble fraction
1.65 8.48e-03 GO:0005624 membrane fraction
1.55 1.65e-04 GO:0005856 cytoskeleton
1.53 1.62e-02 GO:0000267 cell fraction
1.42 1.99e-03 GO:0005829 cytosol

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
17.83 5.32e-03 GO:0015037 peptide disulfide oxidoreductase activity
5.18 1.92e-02 GO:0015036 disulfide oxidoreductase activity