Motif ID: NFE2L2.p2

Z-value: 2.756


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_1778367730.411.3e-01Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_21340757 8.386


chr22_+_21359175 7.514 IGLV3-25
immunoglobulin lambda variable 3-25
chr22_+_21094094 7.039


chr10_-_76538859 6.947 NM_001007271
NM_001007272
NM_001007273
 DUSP13


dual specificity phosphatase 13


chr19_-_54350457 6.717 NM_002152
 HRC
histidine rich calcium binding protein
chr22_+_21484240 6.371


chr22_+_21053972 5.676


chr22_+_21393107 5.624 IGLJ3
immunoglobulin lambda joining 3
chr22_+_21079355 5.583


chr22_+_21370394 5.485 IGL@
immunoglobulin lambda locus
chr6_-_31853027 5.092 NM_025258
 C6orf27
chromosome 6 open reading frame 27
chrX_-_70243362 5.087 NM_001025265
 CXorf65
chromosome X open reading frame 65
chr22_+_21495273 5.084


chrX_-_100527799 4.930 NM_000061
 BTK
Bruton agammaglobulinemia tyrosine kinase
chr15_+_36776090 4.823 NM_207444
 C15orf53
chromosome 15 open reading frame 53
chr17_+_77910411 4.810 NM_207459
 TEX19
testis expressed 19
chr4_-_977163 4.784 NM_022042
NM_134425
NM_213613
 SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr16_+_28413421 4.747 NM_018690
 APOBR
apolipoprotein B receptor
chr17_+_72883759 4.740 NM_001113494
 SEPT9
septin 9
chr22_+_20316968 4.690 NM_152612
 CCDC116
coiled-coil domain containing 116

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
6.02 2.46e-04 GO:0032313 regulation of Rab GTPase activity
6.02 2.46e-04 GO:0032483 regulation of Rab protein signal transduction
5.68 5.18e-04 GO:0006521 regulation of cellular amino acid metabolic process
5.32 4.41e-04 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
5.32 4.41e-04 GO:0072395 signal transduction involved in cell cycle checkpoint
5.32 4.41e-04 GO:0072401 signal transduction involved in DNA integrity checkpoint
5.32 4.41e-04 GO:0072404 signal transduction involved in G1/S transition checkpoint
5.32 4.41e-04 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
5.32 4.41e-04 GO:0072422 signal transduction involved in DNA damage checkpoint
5.32 4.41e-04 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
5.32 4.41e-04 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
5.07 8.31e-04 GO:0071158 positive regulation of cell cycle arrest
4.90 5.25e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.77 1.82e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
4.71 5.21e-03 GO:0033238 regulation of cellular amine metabolic process
4.52 6.72e-04 GO:0051351 positive regulation of ligase activity
4.51 1.59e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
4.46 1.89e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
4.34 2.65e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
4.24 3.68e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
6.25 2.50e-07 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
5.91 7.46e-05 GO:0005097 Rab GTPase activator activity
5.79 2.43e-03 GO:0003823 antigen binding
3.31 3.43e-02 GO:0005099 Ras GTPase activator activity