Motif ID: NFIL3.p2

Z-value: 1.222


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIL3chr9_-_93225780-0.553.3e-02Click!


Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_33139349 1.968 NM_004006
DMD
dystrophin
chr22_-_34564611 1.917 RPL41P5
ribosomal protein L41 pseudogene 5
chr6_-_2785682 1.912 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr2_-_133895795 1.886 NCKAP5
NCK-associated protein 5
chr17_-_19592178 1.835 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr4_-_77147625 1.726 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr8_+_70567634 1.687 SULF1
sulfatase 1
chr2_-_31491102 1.656 NM_000379
XDH
xanthine dehydrogenase
chr9_+_27514311 1.581 NM_020124
IFNK
interferon, kappa
chr5_-_111119846 1.561 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr2_-_31491057 1.472 XDH
xanthine dehydrogenase
chr10_-_82039158 1.454 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr2_-_213723298 1.426 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr12_-_123568781 1.400


chr4_-_153820535 1.376 NM_152680
TMEM154
transmembrane protein 154
chr1_+_86785346 1.366 NM_012128
CLCA4
chloride channel accessory 4
chr3_-_159872960 1.320 NM_020169
LXN
latexin
chr19_-_3936460 1.294 NM_001961
EEF2
eukaryotic translation elongation factor 2
chr4_+_74921136 1.288 NM_002993
CXCL6
chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr4_+_146820805 1.264 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr5_+_56507029 1.250 NM_001127235
GPBP1
GC-rich promoter binding protein 1
chr14_+_95792299 1.242 NM_000710
BDKRB1
bradykinin receptor B1
chr16_-_69876262 1.232 FTSJD1
FtsJ methyltransferase domain containing 1
chr20_+_2030527 1.211 NM_080836
STK35
serine/threonine kinase 35
chr12_-_116283793 1.207 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr8_+_70567581 1.198 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr2_+_64540843 1.195 HSPC159
galectin-related protein
chr7_+_134114701 1.178 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr19_-_3936343 1.172 EEF2
eukaryotic translation elongation factor 2
chr3_+_152970904 1.167 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr17_+_55098280 1.137 CLTC
clathrin, heavy chain (Hc)
chr2_-_192420168 1.100 NM_004657
SDPR
serum deprivation response
chr8_+_94999167 1.077 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr1_+_194887630 1.075 NM_000186
NM_001014975
CFH

complement factor H

chr12_-_44407515 1.056 LOC400027
hypothetical LOC400027
chr13_+_96726415 1.049 MBNL2
muscleblind-like 2 (Drosophila)
chr1_-_109957195 1.047 NM_005272
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr17_-_26665144 1.042 EVI2B
ecotropic viral integration site 2B
chr3_+_130014957 1.033 RAB7A
RAB7A, member RAS oncogene family
chr20_-_55718982 1.021 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr17_-_26672757 1.020 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr17_+_36515166 1.019 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr15_-_63871492 0.999 DENND4A
DENN/MADD domain containing 4A
chr9_-_32540818 0.985 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr5_-_94443300 0.971 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr22_+_39817733 0.968 EP300
E1A binding protein p300
chr1_-_151614681 0.965 NM_005621
S100A12
S100 calcium binding protein A12
chr21_-_26345294 0.913


chr1_+_65503011 0.906 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_46140015 0.890 NM_052855
ANKRD40
ankyrin repeat domain 40
chr8_-_130868315 0.882 NM_031415
GSDMC
gasdermin C
chr5_-_94442941 0.870 MCTP1
multiple C2 domains, transmembrane 1
chr17_+_36493927 0.864 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr13_-_37070862 0.857 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr6_-_136889302 0.832 MAP7
microtubule-associated protein 7
chr6_+_50894397 0.830 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr11_+_4799126 0.826 NM_001004753
OR51F2
olfactory receptor, family 51, subfamily F, member 2
chr12_-_44407756 0.812 LOC400027
hypothetical LOC400027
chr4_+_123873306 0.797 NM_001178007
NM_152618
BBS12

Bardet-Biedl syndrome 12

chr20_+_33223434 0.790 NM_006404
PROCR
protein C receptor, endothelial
chr17_-_36528113 0.784 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr11_+_65023038 0.764 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr2_+_102294393 0.764 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr3_-_113842652 0.755 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr8_-_17797127 0.719 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr3_+_23962518 0.703 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_-_101316038 0.696 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr20_+_4614796 0.686 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr22_-_27787793 0.682 NM_015370
C22orf31
chromosome 22 open reading frame 31
chr2_+_113542017 0.679 NM_173161
IL1F10
interleukin 1 family, member 10 (theta)
chr9_-_122679387 0.665 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr4_+_119174947 0.655 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr4_+_88187215 0.654 AFF1
AF4/FMR2 family, member 1
chr8_-_110689396 0.649 SYBU
syntabulin (syntaxin-interacting)
chr5_-_52441044 0.645 NM_004531
MOCS2
molybdenum cofactor synthesis 2
chr15_-_53996597 0.645 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr13_+_28900776 0.633 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr17_-_38979178 0.628 NM_001079675
ETV4
ets variant 4
chr2_-_133145539 0.608 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr1_+_176577228 0.604 NM_004841
RASAL2
RAS protein activator like 2
chr18_-_35634247 0.593 LOC647946
hypothetical LOC647946
chr4_+_3341521 0.584 NM_198227
RGS12
regulator of G-protein signaling 12
chr1_-_54183833 0.579 NM_016126
HSPB11
heat shock protein family B (small), member 11
chr11_+_93394025 0.574 NM_001098672
HEPHL1
hephaestin-like 1
chr1_-_177106702 0.563 NM_004673
ANGPTL1
angiopoietin-like 1
chr8_+_69026895 0.562 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr3_+_62280435 0.561 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr1_+_161305188 0.558 NM_005613
RGS4
regulator of G-protein signaling 4
chr13_+_96672541 0.554 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr13_+_96672705 0.554 MBNL2
muscleblind-like 2 (Drosophila)
chr17_-_70901303 0.546 GRB2
growth factor receptor-bound protein 2
chr6_-_136888771 0.544 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr5_+_140235114 0.539 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr7_+_142692165 0.534 NM_153345
TMEM139
transmembrane protein 139
chr9_+_17568952 0.532 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr16_-_52094613 0.532 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr10_+_135190855 0.531 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr2_-_98646367 0.531 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_-_150599105 0.527 NM_001014342
FLG2
filaggrin family member 2
chr1_+_24713396 0.520 RCAN3
RCAN family member 3
chr3_+_191588354 0.514 NM_006580
CLDN16
claudin 16
chr4_+_141397889 0.513 NM_032547
SCOC
short coiled-coil protein
chr6_-_41810712 0.512 NM_007162
TFEB
transcription factor EB
chr11_+_35596310 0.511 NM_014344
FJX1
four jointed box 1 (Drosophila)
chrX_+_56772391 0.484 LOC550643
hypothetical LOC550643
chr16_+_80086454 0.484 NM_030629
CMIP
c-Maf-inducing protein
chr9_+_674193 0.480


chr14_+_61532293 0.474 NM_031914
SYT16
synaptotagmin XVI
chrX_-_131919896 0.469 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr9_-_122679283 0.468 PHF19
PHD finger protein 19
chr12_-_121753795 0.459 NM_177551
GPR109A
G protein-coupled receptor 109A
chr6_+_153060722 0.443 NM_025107
MYCT1
myc target 1
chr4_-_74307637 0.435 ANKRD17
ankyrin repeat domain 17
chr5_-_139993469 0.434 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr2_+_87536106 0.427 NCRNA00152
non-protein coding RNA 152
chr14_+_101345878 0.423 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr1_+_149165438 0.417 NM_001145415
NM_012432
SETDB1

SET domain, bifurcated 1

chr9_+_15542871 0.414 NM_173550
C9orf93
chromosome 9 open reading frame 93
chr18_+_30875297 0.411 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr1_+_195213289 0.409 NM_030787
CFHR5
complement factor H-related 5
chr17_-_64649608 0.408 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr12_+_50633430 0.406 NM_020327
ACVR1B
activin A receptor, type IB
chr17_+_7402788 0.405 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_-_104834344 0.398 LOC100506421
hypothetical LOC100506421
chr10_-_119795663 0.392 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr1_+_151081953 0.390 NM_001128600
LCE6A
late cornified envelope 6A
chr6_-_64087806 0.385 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr17_-_64752550 0.383 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr5_-_56814310 0.380 NM_001017992
ACTBL2
actin, beta-like 2
chr7_+_80145461 0.370 CD36
CD36 molecule (thrombospondin receptor)
chr1_-_245763763 0.369 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr17_-_36074812 0.365 NM_152349
KRT222
keratin 222
chr3_+_103029523 0.363 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr6_-_134415311 0.357 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr17_-_31337798 0.354 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr4_-_70760381 0.354 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr8_-_102286695 0.353 ZNF706
zinc finger protein 706
chr4_-_87989291 0.349 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr12_-_7487989 0.346 NM_174941
CD163L1
CD163 molecule-like 1
chr17_-_59204622 0.344 CCDC47
coiled-coil domain containing 47
chr4_+_110574420 0.342 SEC24B
SEC24 family, member B (S. cerevisiae)
chr17_-_36559579 0.341 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr19_+_56671649 0.340 NM_001080405
CEACAM18
carcinoembryonic antigen-related cell adhesion molecule 18
chr2_+_87536174 0.340 NCRNA00152
non-protein coding RNA 152
chr10_+_4995453 0.337 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr8_-_103735194 0.336 NM_001032282
KLF10
Kruppel-like factor 10
chr9_-_98104206 0.334 NM_000197
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr3_-_192063158 0.329 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr11_-_128399218 0.329 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_+_57093030 0.324 NM_000562
C8A
complement component 8, alpha polypeptide
chr17_-_26665194 0.321 EVI2B
ecotropic viral integration site 2B
chr2_-_45648608 0.319 SRBD1
S1 RNA binding domain 1
chr12_+_110328126 0.318 NM_005475
SH2B3
SH2B adaptor protein 3
chr1_+_144236346 0.317 NM_003637
ITGA10
integrin, alpha 10
chr11_+_111552298 0.314 NM_001037290
BCO2
beta-carotene oxygenase 2
chr8_-_11891168 0.313 NM_001033019
DEFB134
defensin, beta 134
chr5_+_36642424 0.311 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr20_+_36643251 0.309 NM_001018082
ADIG
adipogenin
chr4_+_81325447 0.307 NM_020226
PRDM8
PR domain containing 8
chr5_-_158567411 0.306 NM_144726
RNF145
ring finger protein 145
chr8_+_22075112 0.298 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr5_+_36642213 0.291 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr12_-_73889777 0.284 NM_139136
NM_139137
NM_153748
KCNC2


potassium voltage-gated channel, Shaw-related subfamily, member 2


chr10_-_102663070 0.283


chr8_-_102287083 0.282 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr5_-_79982584 0.282 NM_001190470
MTRNR2L2
MT-RNR2-like 2
chr2_-_188127294 0.280 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr21_+_18539016 0.279 NM_024944
CHODL
chondrolectin
chr7_+_89681069 0.276 NM_001040666
STEAP2
six transmembrane epithelial antigen of the prostate 2
chr7_+_20653490 0.275 NM_001163942
NM_001163993
NM_178559
ABCB5


ATP-binding cassette, sub-family B (MDR/TAP), member 5


chr2_-_188021117 0.274 NM_005795
CALCRL
calcitonin receptor-like
chr5_-_139992621 0.273 NM_000591
CD14
CD14 molecule
chr6_-_50045296 0.272 NM_001037729
DEFB113
defensin, beta 113
chrX_-_84521052 0.266 POF1B
premature ovarian failure, 1B
chr5_-_38592439 0.265 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr4_-_24590867 0.264 NM_173463
CCDC149
coiled-coil domain containing 149
chr15_+_56217686 0.263 NM_020980
AQP9
aquaporin 9
chr10_+_4995597 0.261 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr4_-_96689373 0.261 NM_003728
UNC5C
unc-5 homolog C (C. elegans)
chrX_+_38548316 0.258 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr1_-_42157077 0.255 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr7_+_150321771 0.253 NM_001160109
NM_001160110
NM_001160111
NOS3


nitric oxide synthase 3 (endothelial cell)


chr1_+_144236398 0.253 ITGA10
integrin, alpha 10
chr2_+_135392857 0.253 NM_001241
NM_058241
CCNT2

cyclin T2

chr8_-_92122219 0.252 NM_018710
TMEM55A
transmembrane protein 55A
chr17_-_26665220 0.251 NM_006495
EVI2B
ecotropic viral integration site 2B
chr3_+_44667504 0.251 ZNF35
zinc finger protein 35
chr4_+_120167264 0.250 SYNPO2
synaptopodin 2
chr10_+_91077581 0.250 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_+_135392879 0.247 CCNT2
cyclin T2
chr12_-_69317441 0.247 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_-_114231519 0.247 BCL2L15
BCL2-like 15
chr5_-_14924555 0.246 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr3_-_102194938 0.244 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chrX_+_117992603 0.244 LONRF3
LON peptidase N-terminal domain and ring finger 3
chrX_+_38548016 0.243 NM_021242
MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr10_-_99780336 0.242 CRTAC1
cartilage acidic protein 1
chr7_-_31347032 0.239 NM_022728
NEUROD6
neurogenic differentiation 6
chr14_-_69333624 0.237 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr12_-_28016182 0.234 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.30 1.15e-02 GO:0008202 steroid metabolic process
12.61 4.06e-02 GO:0015721 bile acid and bile salt transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.11 6.25e-05 GO:0044421 extracellular region part
2.09 2.16e-03 GO:0005615 extracellular space
1.57 8.15e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
40.35 1.13e-04 GO:0047023 androsterone dehydrogenase activity
30.26 1.82e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity