Motif ID: NFKB1_REL_RELA.p2

Z-value: 2.323


Transcription factors associated with NFKB1_REL_RELA.p2:

Gene SymbolEntrez IDGene Name
NFKB1 4790 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
REL 5966 v-rel reticuloendotheliosis viral oncogene homolog (avian)
RELA 5970 v-rel reticuloendotheliosis viral oncogene homolog A (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFKB1chr4_+_103641854-0.543.8e-02Click!
RELAchr11_-_651824110.468.8e-02Click!
RELchr2_+_609622280.204.6e-01Click!


Activity profile for motif NFKB1_REL_RELA.p2.

activity profile for motif NFKB1_REL_RELA.p2


Sorted Z-values histogram for motif NFKB1_REL_RELA.p2

Sorted Z-values for motif NFKB1_REL_RELA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFKB1_REL_RELA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_35277942 4.099 NM_198844
NM_199321
ZPBP2

zona pellucida binding protein 2

chr19_+_40632456 3.772 NM_005306
FFAR2
free fatty acid receptor 2
chr2_+_219453487 3.683 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr20_-_4743768 3.338 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr2_-_231498184 3.083 NM_005683
GPR55
G protein-coupled receptor 55
chr7_+_142723340 2.874 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr17_-_33178987 2.700 HNF1B
HNF1 homeobox B
chr1_-_200397300 2.593 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr6_-_30188845 2.544 NM_007028
TRIM31
tripartite motif containing 31
chr3_-_58175437 2.469 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr17_+_22823151 2.452 NM_014238
KSR1
kinase suppressor of ras 1
chr19_-_7672978 2.292 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr17_-_31231421 2.244 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr19_+_17499064 2.242 FAM129C
family with sequence similarity 129, member C
chr3_-_13089547 2.153 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr16_+_49288550 2.145 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr11_-_60880799 2.026 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr14_-_95250155 1.935 NM_001098725
NM_021966
TCL1A

T-cell leukemia/lymphoma 1A

chr20_-_44370537 1.871 CDH22
cadherin 22, type 2
chr18_-_26996742 1.847 NM_004948
NM_024421
DSC1

desmocollin 1

chr17_-_16816113 1.764 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr11_-_18226743 1.667 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr6_+_31647854 1.651 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr9_+_139047441 1.640 C9orf139
chromosome 9 open reading frame 139
chr1_+_200246370 1.628 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr20_-_55628852 1.625 NM_001160417
NM_001160418
NM_001160419
NM_030776
ZBP1



Z-DNA binding protein 1



chr1_-_205210567 1.622 NM_001122979
NM_001170631
NM_032029
FCAMR


Fc receptor, IgA, IgM, high affinity


chr22_-_35875890 1.619 NM_000878
IL2RB
interleukin 2 receptor, beta
chr17_-_33179118 1.606 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr3_-_113334657 1.594 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr3_-_71715431 1.562 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr14_+_102313566 1.556 NM_003300
NM_145725
NM_145726
TRAF3


TNF receptor-associated factor 3


chr6_+_31648071 1.552 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr10_-_21854616 1.536 NM_207371
C10orf140
chromosome 10 open reading frame 140
chr12_-_53661888 1.523 NM_001098815
KIAA0748
KIAA0748
chr12_+_6925997 1.517 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_102313585 1.512 TRAF3
TNF receptor-associated factor 3
chr1_+_67404756 1.504 NM_144701
IL23R
interleukin 23 receptor
chr12_+_6926014 1.475 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr2_+_68815416 1.454 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr15_+_30797466 1.449 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr1_+_200246312 1.432 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr15_-_38185578 1.411 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr9_-_139047112 1.391 NM_004479
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr11_+_18244383 1.386 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr1_+_45046740 1.377 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr19_+_10388448 1.372 PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_-_35506493 1.369 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr1_+_154389945 1.365 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr5_-_134810696 1.345 NM_130848
C5orf20
chromosome 5 open reading frame 20
chr1_-_181826633 1.344 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr19_+_4180494 1.340 NM_005755
EBI3
Epstein-Barr virus induced 3
chr1_-_27834210 1.339 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr16_+_87232501 1.326 NM_013278
IL17C
interleukin 17C
chr8_-_70909754 1.323 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr1_-_59020875 1.321 JUN
jun proto-oncogene
chr19_-_48977247 1.304 NM_002250
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr11_-_65070625 1.296 LTBP3
latent transforming growth factor beta binding protein 3
chr1_-_159275334 1.290 TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr19_+_47073029 1.286 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr1_-_24386324 1.276 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr1_-_223907283 1.276 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr1_+_26744929 1.274 NM_001006665
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr9_+_126094067 1.272 NM_001166170
NM_001166171
NEK6

NIMA (never in mitosis gene a)-related kinase 6

chr1_-_159099090 1.260 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr3_-_196787563 1.244 APOD
apolipoprotein D
chr20_+_29526751 1.244 NM_014012
REM1
RAS (RAD and GEM)-like GTP-binding 1
chr19_+_3087026 1.242 NM_002068
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
chr19_-_17819773 1.236 JAK3
Janus kinase 3
chr2_+_113452066 1.232 NM_019618
IL1F9
interleukin 1 family, member 9
chr1_+_26744893 1.223 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_-_17819814 1.222 NM_000215
JAK3
Janus kinase 3
chr14_-_69725342 1.220 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr19_+_5082230 1.206 KDM4B
lysine (K)-specific demethylase 4B
chr11_+_118259684 1.197 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr15_+_79376295 1.182 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chrX_+_12795111 1.181 NM_016562
TLR7
toll-like receptor 7
chr10_-_6144119 1.175 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr16_+_28903647 1.174 NM_001014989
LAT
linker for activation of T cells
chr16_-_73798539 1.171 NM_001025200
CTRB1
CTRB2
chymotrypsinogen B1
chymotrypsinogen B2
chr19_+_13066956 1.159 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_111980044 1.133 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr4_-_77163609 1.128 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr17_+_69974116 1.113 NM_007261
CD300A
CD300a molecule
chr6_-_29635680 1.104 NM_006398
UBD
ubiquitin D
chr10_-_105427898 1.083 SH3PXD2A
SH3 and PX domains 2A
chr16_+_66128843 1.069 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr9_-_70818829 1.064 NM_002732
PRKACG
protein kinase, cAMP-dependent, catalytic, gamma
chr1_-_21489235 1.060 NM_001113349
ECE1
endothelin converting enzyme 1
chr9_+_126094388 1.058 NM_001166169
NEK6
NIMA (never in mitosis gene a)-related kinase 6
chrX_+_78087484 1.051 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr1_-_200395741 1.042 NM_080588
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr1_-_159275357 1.038 NM_001113205
NM_001113206
NM_001113207
TSTD1


F11R
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1


F11 receptor
chr12_+_47658502 1.037 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr19_-_4491024 1.033 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr12_-_74711474 1.017 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr15_+_57517564 1.016 NM_152450
FAM81A
family with sequence similarity 81, member A
chr10_+_102746819 1.015 NM_032429
LZTS2
leucine zipper, putative tumor suppressor 2
chr2_-_25390266 0.981 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr3_+_123279439 0.978 NM_006889
CD86
CD86 molecule
chr2_+_237143118 0.966 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr2_-_74522563 0.966 NM_001015055
RTKN
rhotekin
chr7_-_44985084 0.959 MYO1G
myosin IG
chr14_-_50631407 0.958 TRIM9
tripartite motif containing 9
chr6_-_29635456 0.945 UBD
ubiquitin D
chr19_-_4491078 0.941 LRG1
leucine-rich alpha-2-glycoprotein 1
chr14_-_106202262 0.935 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr8_+_145158432 0.934 NM_001134374
NM_198572
SPATC1

spermatogenesis and centriole associated 1

chr16_-_31135895 0.927 NM_152901
PYDC1
PYD (pyrin domain) containing 1
chr1_-_200396354 0.925 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr6_+_32713160 0.922 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr19_+_17723285 0.914 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr19_-_44427446 0.905 NM_172139
IL28B
interleukin 28B (interferon, lambda 3)
chr22_-_35970230 0.903 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_+_55018925 0.896 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr4_-_120768563 0.891 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr11_-_76059435 0.891 NM_001128922
LRRC32
leucine rich repeat containing 32
chr8_+_22913008 0.889 NM_015178
RHOBTB2
Rho-related BTB domain containing 2
chr16_+_28903870 0.886 NM_001014987
NM_001014988
NM_014387
LAT


linker for activation of T cells


chr1_-_200396328 0.880 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr7_-_150737980 0.867 NM_198285
WDR86
WD repeat domain 86
chr17_+_8865547 0.867 NM_004822
NTN1
netrin 1
chr15_+_74139325 0.866 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr10_+_12431477 0.863 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr5_+_175597943 0.862 NM_198567
C5orf25
chromosome 5 open reading frame 25
chr16_+_84490267 0.859 NM_002163
IRF8
interferon regulatory factor 8
chr1_-_154226484 0.856 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_-_207892420 0.852 NM_000228
LAMB3
laminin, beta 3
chr6_-_167491305 0.847 NM_005299
GPR31
G protein-coupled receptor 31
chr17_+_35853177 0.846 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr18_-_6404900 0.843 NM_173464
L3MBTL4
l(3)mbt-like 4 (Drosophila)
chr2_+_231968578 0.842 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr20_+_44070946 0.837 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr1_+_199130571 0.829 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr22_-_40673025 0.824 NM_001002876
NM_024053
CENPM

centromere protein M

chr1_-_181826292 0.823 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr14_-_23878871 0.816 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr17_+_7402315 0.810 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr7_-_44985202 0.806 NM_033054
MYO1G
myosin IG
chr1_+_154390939 0.805 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_95343716 0.800 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr20_-_61669550 0.793 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr19_+_55614006 0.785 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr2_-_74522534 0.785 RTKN
rhotekin
chr1_+_35104120 0.785


chr19_-_16111594 0.785


chr12_+_6819635 0.780 NM_002075
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr20_+_58146916 0.780 LOC284757
hypothetical protein LOC284757
chr22_+_21094094 0.777


chr5_-_54866126 0.772 NM_003711
NM_176895
RNF138P1
PPAP2A

ring finger protein 138 pseudogene 1
phosphatidic acid phosphatase type 2A

chr7_-_44985175 0.769 MYO1G
myosin IG
chr2_+_233633279 0.767 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr10_-_90601655 0.765 NM_144590
ANKRD22
ankyrin repeat domain 22
chr2_+_12775814 0.765


chr1_+_111571803 0.759 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr6_+_14225932 0.759 CD83
CD83 molecule
chr7_+_150669741 0.746 NM_016118
NUB1
negative regulator of ubiquitin-like proteins 1
chr9_-_114520184 0.746 NM_021218
C9orf80
chromosome 9 open reading frame 80
chr4_-_140317686 0.745 ELF2
E74-like factor 2 (ets domain transcription factor)
chr6_+_149109841 0.740 NM_005715
UST
uronyl-2-sulfotransferase
chr19_-_52426055 0.736 NM_014417
BBC3
BCL2 binding component 3
chr2_-_74522513 0.735 RTKN
rhotekin
chr15_-_72804763 0.734 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr17_-_58877276 0.732 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr12_+_55808696 0.729 LRP1
low density lipoprotein receptor-related protein 1
chr12_+_55808514 0.726 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr7_+_50318801 0.723 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr17_+_45993338 0.715 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr17_+_37694007 0.711 STAT5A
signal transducer and activator of transcription 5A
chr11_+_60495690 0.710 NM_006725
CD6
CD6 molecule
chr1_+_17719405 0.709 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr18_+_3439972 0.708 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr6_+_158654464 0.706 TULP4
tubby like protein 4
chr5_+_167651063 0.706 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr12_-_15833383 0.703 EPS8
epidermal growth factor receptor pathway substrate 8
chr1_-_153107084 0.702


chr12_-_47651812 0.701 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr1_+_159032551 0.700 NM_001033667
NM_002348
LY9

lymphocyte antigen 9

chr19_+_11936868 0.700 NM_001012753
ZNF763
zinc finger protein 763
chr17_+_44429748 0.695 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chrX_+_133993984 0.690 NM_001078171
FAM127A
family with sequence similarity 127, member A
chr15_+_64782468 0.685 SMAD6
SMAD family member 6
chr15_-_41879426 0.680 NM_001033517
SERINC4
serine incorporator 4
chr2_+_233633348 0.676 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr17_+_52026058 0.673 NM_005450
NOG
noggin
chr22_-_35970133 0.670 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_+_35658852 0.666 NM_016300
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr6_-_32659958 0.659 HLA-DRB1
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 5
chr1_-_41722883 0.655 NM_001956
EDN2
endothelin 2
chrX_+_7147471 0.651 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr10_+_111959978 0.650 NM_001008541
MXI1
MAX interactor 1
chr12_-_6611075 0.650 NM_001142961
LPAR5
lysophosphatidic acid receptor 5
chr15_-_40173949 0.646 NM_178034
PLA2G4D
phospholipase A2, group IVD (cytosolic)
chr12_+_92488932 0.645 SOCS2
suppressor of cytokine signaling 2
chr19_+_44697592 0.644 NM_182704
SELV
selenoprotein V
chr1_+_100777044 0.641 GPR88
G protein-coupled receptor 88
chr19_-_11549441 0.640 ACP5
acid phosphatase 5, tartrate resistant
chr1_+_152644292 0.640 NM_000565
NM_181359
IL6R

interleukin 6 receptor

chr10_+_102749597 0.637 LZTS2
leucine zipper, putative tumor suppressor 2
chr22_+_38720881 0.632 NM_138435
FAM83F
family with sequence similarity 83, member F

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 2.01e-06 GO:0050794 regulation of cellular process
1.40 3.35e-06 GO:0048523 negative regulation of cellular process
1.37 1.06e-05 GO:0048519 negative regulation of biological process
1.35 1.58e-05 GO:0048522 positive regulation of cellular process
1.15 2.64e-05 GO:0065007 biological regulation
1.67 3.68e-05 GO:0006955 immune response
1.32 4.13e-05 GO:0048518 positive regulation of biological process
1.16 5.54e-05 GO:0050789 regulation of biological process
1.48 1.81e-04 GO:0002376 immune system process
1.09 3.87e-04 GO:0009987 cellular process
1.65 5.63e-04 GO:0010628 positive regulation of gene expression
1.24 7.04e-04 GO:0023052 signaling
1.47 9.12e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.24 2.53e-03 GO:0007165 signal transduction
1.57 4.02e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.71 5.12e-03 GO:0051222 positive regulation of protein transport
1.42 5.16e-03 GO:0009893 positive regulation of metabolic process
1.62 5.34e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.45 7.67e-03 GO:0010941 regulation of cell death
1.75 8.26e-03 GO:0007243 intracellular protein kinase cascade
1.75 8.26e-03 GO:0023014 signal transduction via phosphorylation event
2.29 9.35e-03 GO:0034762 regulation of transmembrane transport
1.20 9.56e-03 GO:0051716 cellular response to stimulus
1.56 1.07e-02 GO:0002682 regulation of immune system process
3.39 1.13e-02 GO:0046824 positive regulation of nucleocytoplasmic transport
2.04 1.13e-02 GO:0051249 regulation of lymphocyte activation
1.63 1.13e-02 GO:0006928 cellular component movement
3.25 1.17e-02 GO:0032388 positive regulation of intracellular transport
1.57 1.21e-02 GO:0051254 positive regulation of RNA metabolic process
1.44 1.29e-02 GO:0043067 regulation of programmed cell death
1.45 1.29e-02 GO:0042981 regulation of apoptosis
1.41 1.37e-02 GO:0031325 positive regulation of cellular metabolic process
3.48 1.46e-02 GO:0034764 positive regulation of transmembrane transport
1.46 1.53e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
4.02 1.83e-02 GO:0060443 mammary gland morphogenesis
1.58 1.89e-02 GO:0001932 regulation of protein phosphorylation
1.47 2.01e-02 GO:0050793 regulation of developmental process
1.22 2.03e-02 GO:0007275 multicellular organismal development
3.26 2.14e-02 GO:0090316 positive regulation of intracellular protein transport
1.63 2.14e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.66 2.34e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.55 2.47e-02 GO:0045595 regulation of cell differentiation
1.61 2.62e-02 GO:0051253 negative regulation of RNA metabolic process
1.93 2.97e-02 GO:0002694 regulation of leukocyte activation
1.31 3.02e-02 GO:0006464 protein modification process
1.54 3.19e-02 GO:0042325 regulation of phosphorylation
1.56 3.62e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
3.42 3.74e-02 GO:0042307 positive regulation of protein import into nucleus
1.57 3.80e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.47 4.02e-02 GO:0009891 positive regulation of biosynthetic process
1.50 4.70e-02 GO:2000026 regulation of multicellular organismal development
1.47 4.77e-02 GO:0031328 positive regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 1.16e-04 GO:0044459 plasma membrane part
1.19 1.47e-03 GO:0071944 cell periphery
1.19 1.81e-03 GO:0005886 plasma membrane
2.08 3.50e-02 GO:0009897 external side of plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 4.62e-04 GO:0005515 protein binding
1.45 3.34e-03 GO:0001071 nucleic acid binding transcription factor activity
1.45 3.34e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.70 4.95e-02 GO:0016563 transcription activator activity