Motif ID: NFY{A,B,C}.p2

Z-value: 2.849


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYCchr1_+_409300800.703.8e-03Click!
NFYAchr6_+_411486650.048.8e-01Click!
NFYBchr12_-_1030559240.048.9e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_41978464 1.932 NM_017886
 ULK4
unc-51-like kinase 4 (C. elegans)
chr5_+_108112537 1.920 FER
fer (fps/fes related) tyrosine kinase
chr7_+_129497637 1.659 KLHDC10
kelch domain containing 10
chr19_-_14467939 1.650 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
 GIPC1





GIPC PDZ domain containing family, member 1





chr11_+_61473931 1.604 NM_001139443
NM_004183
 BEST1

bestrophin 1

chr19_-_14467890 1.597 GIPC1
GIPC PDZ domain containing family, member 1
chr7_+_129497572 1.591 NM_014997
 KLHDC10
kelch domain containing 10
chr15_-_73719546 1.571 NM_018285
 IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr1_-_46370837 1.559 NM_003629
NM_001114172
 PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr1_-_152394215 1.506 NM_001159484
NM_207308
 NUP210L

nucleoporin 210kDa-like

chr6_+_160103500 1.479 ACAT2
acetyl-CoA acetyltransferase 2
chr22_-_21193037 1.366 ZNF280B
zinc finger protein 280B
chrX_+_70438352 1.320 NM_012278
 ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr2_+_85676347 1.320 NM_016494
 RNF181
ring finger protein 181
chr7_+_129497808 1.318 KLHDC10
kelch domain containing 10
chr1_-_159257486 1.317 F11R
F11 receptor
chr2_-_96237665 1.314 STARD7
StAR-related lipid transfer (START) domain containing 7
chr6_-_25834733 1.291 NM_170745
 HIST1H2AA
histone cluster 1, H2aa
chr6_+_25834983 1.284 NM_170610
 HIST1H2BA
histone cluster 1, H2ba
chr6_+_31903374 1.244 NM_005346
 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 78 entries
enrichment   p-value GO term description
8.28 3.86e-04 GO:0002566 somatic diversification of immune receptors via somatic mutation
8.28 3.86e-04 GO:0016446 somatic hypermutation of immunoglobulin genes
5.13 3.83e-03 GO:0006298 mismatch repair
5.08 1.86e-06 GO:0006695 cholesterol biosynthetic process
4.78 9.03e-07 GO:0016126 sterol biosynthetic process
4.04 1.34e-02 GO:0007131 reciprocal meiotic recombination
3.79 3.16e-02 GO:0000724 double-strand break repair via homologous recombination
3.79 3.16e-02 GO:0000725 recombinational repair
3.73 8.72e-04 GO:0000819 sister chromatid segregation
3.55 8.50e-03 GO:0000070 mitotic sister chromatid segregation
3.50 1.49e-09 GO:0007059 chromosome segregation
3.41 1.04e-07 GO:0006334 nucleosome assembly
3.40 4.29e-09 GO:0065004 protein-DNA complex assembly
3.37 2.01e-06 GO:0000236 mitotic prometaphase
3.30 6.61e-09 GO:0071824 protein-DNA complex subunit organization
3.26 1.25e-07 GO:0034728 nucleosome organization
3.23 5.42e-07 GO:0031497 chromatin assembly
3.13 7.69e-09 GO:0006323 DNA packaging
3.11 3.28e-09 GO:0006310 DNA recombination
2.88 3.89e-08 GO:0071103 DNA conformation change

Gene overrepresentation in compartment category:

Showing 1 to 20 of 56 entries
enrichment   p-value GO term description
7.77 3.72e-02 GO:0032389 MutLalpha complex
6.21 2.75e-03 GO:0032300 mismatch repair complex
5.93 1.73e-02 GO:0032391 photoreceptor connecting cilium
3.61 3.62e-06 GO:0000786 nucleosome
3.39 2.13e-04 GO:0000794 condensed nuclear chromosome
3.19 3.14e-05 GO:0000777 condensed chromosome kinetochore
3.11 3.23e-05 GO:0000779 condensed chromosome, centromeric region
3.07 1.36e-06 GO:0032993 protein-DNA complex
2.93 9.66e-09 GO:0000793 condensed chromosome
2.83 1.62e-04 GO:0000776 kinetochore
2.69 4.90e-02 GO:0030496 midbody
2.61 3.56e-06 GO:0000775 chromosome, centromeric region
2.60 3.11e-02 GO:0034399 nuclear periphery
2.52 8.84e-07 GO:0044454 nuclear chromosome part
2.46 2.03e-18 GO:0044427 chromosomal part
2.42 4.41e-21 GO:0005694 chromosome
2.40 2.87e-08 GO:0000785 chromatin
2.32 2.21e-05 GO:0005819 spindle
2.31 2.35e-06 GO:0000228 nuclear chromosome
1.93 1.02e-03 GO:0005759 mitochondrial matrix

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
9.32 1.20e-04 GO:0032404 mismatch repair complex binding
5.99 1.65e-03 GO:0030983 mismatched DNA binding
3.91 5.62e-03 GO:0004003 ATP-dependent DNA helicase activity
3.86 2.71e-04 GO:0003678 DNA helicase activity
2.91 4.97e-03 GO:0008094 DNA-dependent ATPase activity
1.66 3.54e-02 GO:0016887 ATPase activity
1.45 2.71e-02 GO:0019899 enzyme binding
1.43 3.23e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
1.42 4.27e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.33 1.01e-05 GO:0003677 DNA binding
1.32 1.59e-08 GO:0003676 nucleic acid binding
1.31 1.10e-02 GO:0030554 adenyl nucleotide binding
1.31 1.79e-02 GO:0005524 ATP binding
1.30 2.27e-02 GO:0032559 adenyl ribonucleotide binding
1.26 6.54e-03 GO:0000166 nucleotide binding
1.22 5.26e-14 GO:0005515 protein binding
1.18 5.95e-05 GO:0003824 catalytic activity
1.11 5.12e-12 GO:0005488 binding