Motif ID: NHLH1,2.p2

Z-value: 2.298


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NHLH2chr1_+_1161819270.703.8e-03Click!
NHLH1chr1_+_158603480-0.694.6e-03Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_36515166 4.768 NM_001146041
 KRTAP4-9
keratin associated protein 4-9
chr17_-_36533903 4.477 NM_031854
 KRTAP4-12
keratin associated protein 4-12
chr17_-_36528113 4.161 NM_033059
 KRTAP4-11
keratin associated protein 4-11
chr8_-_24828134 2.900 NEFM
neurofilament, medium polypeptide
chr17_-_36507900 2.894 NM_031960
 KRTAP4-8
keratin associated protein 4-8
chr3_-_73756668 2.494 NM_015009
 PDZRN3
PDZ domain containing ring finger 3
chr13_-_71338144 2.356 DACH1
dachshund homolog 1 (Drosophila)
chr22_-_39964001 2.336 CHADL
chondroadherin-like
chr3_+_185538998 2.319 FAM131A
family with sequence similarity 131, member A
chr9_+_17124974 2.244 NM_001114395
NM_017738
 CNTLN

centlein, centrosomal protein

chr17_+_36493927 2.231 NM_033061
 KRTAP4-7
keratin associated protein 4-7
chr5_+_129268352 2.212 NM_175856
 CHSY3
chondroitin sulfate synthase 3
chr2_+_109112428 2.109 NM_001099289
 SH3RF3
SH3 domain containing ring finger 3
chr13_-_25523164 2.043 NM_001007538
 SHISA2
shisa homolog 2 (Xenopus laevis)
chr2_-_229844198 2.029 NM_001100818
NM_017933
 PID1

phosphotyrosine interaction domain containing 1

chr11_+_12987455 1.899 NM_001080521
 RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr2_-_72228427 1.854 NM_019885
 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr17_-_36436979 1.823 NM_031957
 KRTAP1-5
keratin associated protein 1-5
chr15_+_90738108 1.776 NM_006011
 ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr10_-_15801661 1.755 NM_003638
 ITGA8
integrin, alpha 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 49 entries
enrichment   p-value GO term description
2.19 1.11e-02 GO:0043279 response to alkaloid
1.94 8.07e-03 GO:0007202 activation of phospholipase C activity
1.92 1.13e-02 GO:0010863 positive regulation of phospholipase C activity
1.84 3.99e-02 GO:0010518 positive regulation of phospholipase activity
1.83 2.68e-02 GO:0060541 respiratory system development
1.80 4.97e-02 GO:0060193 positive regulation of lipase activity
1.61 4.91e-02 GO:0007584 response to nutrient
1.54 4.06e-03 GO:0001501 skeletal system development
1.54 6.65e-03 GO:0019932 second-messenger-mediated signaling
1.50 3.88e-02 GO:0031667 response to nutrient levels
1.46 1.72e-06 GO:0030182 neuron differentiation
1.46 2.01e-02 GO:0090066 regulation of anatomical structure size
1.44 1.61e-03 GO:0007417 central nervous system development
1.44 9.91e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.43 4.68e-08 GO:0048468 cell development
1.43 5.24e-04 GO:0048666 neuron development
1.43 4.86e-03 GO:0031175 neuron projection development
1.43 9.67e-03 GO:0048812 neuron projection morphogenesis
1.43 1.77e-02 GO:0007409 axonogenesis
1.41 2.38e-06 GO:0048699 generation of neurons

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.52 8.98e-05 GO:0031012 extracellular matrix
1.49 3.22e-03 GO:0005578 proteinaceous extracellular matrix
1.21 4.25e-02 GO:0005887 integral to plasma membrane
1.20 4.98e-02 GO:0031226 intrinsic to plasma membrane
1.15 4.65e-02 GO:0044459 plasma membrane part
1.07 4.55e-03 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.94 1.71e-02 GO:0005201 extracellular matrix structural constituent