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Motif ID: NHLH1,2.p2

Z-value: 2.298

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_+_36515166	4.768	NM_001146041	KRTAP4-9	keratin associated protein 4-9
chr17_-_36533903	4.477	NM_031854	KRTAP4-12	keratin associated protein 4-12
chr17_-_36528113	4.161	NM_033059	KRTAP4-11	keratin associated protein 4-11
chr8_-_24828134	2.900		NEFM	neurofilament, medium polypeptide
chr17_-_36507900	2.894	NM_031960	KRTAP4-8	keratin associated protein 4-8
chr3_-_73756668	2.494	NM_015009	PDZRN3	PDZ domain containing ring finger 3
chr13_-_71338144	2.356		DACH1	dachshund homolog 1 (Drosophila)
chr22_-_39964001	2.336		CHADL	chondroadherin-like
chr3_+_185538998	2.319		FAM131A	family with sequence similarity 131, member A
chr9_+_17124974	2.244	NM_001114395 NM_017738	CNTLN	centlein, centrosomal protein
chr17_+_36493927	2.231	NM_033061	KRTAP4-7	keratin associated protein 4-7
chr5_+_129268352	2.212	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr2_+_109112428	2.109	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr13_-_25523164	2.043	NM_001007538	SHISA2	shisa homolog 2 (Xenopus laevis)
chr2_-_229844198	2.029	NM_001100818 NM_017933	PID1	phosphotyrosine interaction domain containing 1
chr11_+_12987455	1.899	NM_001080521	RASSF10	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr2_-_72228427	1.854	NM_019885	CYP26B1	cytochrome P450, family 26, subfamily B, polypeptide 1
chr17_-_36436979	1.823	NM_031957	KRTAP1-5	keratin associated protein 1-5
chr15_+_90738108	1.776	NM_006011	ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr10_-_15801661	1.755	NM_003638	ITGA8	integrin, alpha 8
chr5_-_54317102	1.751	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr3_-_62835601	1.729
chr7_-_45927263	1.715	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr4_+_61749540	1.710		LPHN3	latrophilin 3
chr14_-_76807302	1.601	NM_021257	NGB	neuroglobin
chr20_+_13150417	1.572	NM_080826	ISM1	isthmin 1 homolog (zebrafish)
chr17_-_36587965	1.559	NM_033062	KRTAP4-2	keratin associated protein 4-2
chr5_+_159276317	1.556	NM_000679	ADRA1B	adrenergic, alpha-1B-, receptor
chr17_-_7434113	1.552	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr14_-_59001603	1.542		GPR135	G protein-coupled receptor 135
chr13_-_43259032	1.505	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr5_+_113725914	1.502	NM_021614	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr7_+_17304707	1.494	NM_001621	AHR	aryl hydrocarbon receptor
chr6_-_18230829	1.491	NM_198586	NHLRC1	NHL repeat containing 1
chr12_-_50871953	1.480	NM_001081492 NM_182507	KRT80	keratin 80
chr1_-_92724181	1.476	NM_001127216	GFI1	growth factor independent 1 transcription repressor
chr7_+_29200850	1.472		CHN2	chimerin (chimaerin) 2
chr22_-_22652018	1.469	NM_001355	DDT	D-dopachrome tautomerase
chr2_-_219404755	1.466	NM_017431	PRKAG3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit
chr19_+_10597167	1.440	NM_020428	SLC44A2	solute carrier family 44, member 2
chr17_-_7106497	1.422		CLDN7	claudin 7
chr8_+_24827181	1.412		NEFM	neurofilament, medium polypeptide
chr21_-_44795769	1.403	NM_198693	KRTAP10-2	keratin associated protein 10-2
chr1_+_15145001	1.397	NM_001017999	KAZN	kazrin, periplakin interacting protein
chr5_-_136862130	1.386		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr4_-_154929657	1.382	NM_003013	SFRP2	secreted frizzled-related protein 2
chr13_-_35603513	1.379	NM_004734	DCLK1	doublecortin-like kinase 1
chr13_-_35603466	1.374		DCLK1	doublecortin-like kinase 1
chr20_-_9767406	1.363	NM_020341 NM_177990	PAK7	p21 protein (Cdc42/Rac)-activated kinase 7
chr5_-_94646033	1.362	NM_024717	MCTP1	multiple C2 domains, transmembrane 1
chr8_-_16903911	1.361	NM_019851	FGF20	fibroblast growth factor 20
chr9_-_90983195	1.358		SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr14_+_37748345	1.353		SSTR1	somatostatin receptor 1
chr8_+_24827173	1.352	NM_005382	NEFM	neurofilament, medium polypeptide
chr13_-_35603432	1.348		DCLK1	doublecortin-like kinase 1
chr5_+_115326035	1.348	NM_173800	AQPEP	laeverin
chr20_+_19818209	1.348	NM_018993	RIN2	Ras and Rab interactor 2
chr9_-_71476917	1.344	NM_001163	APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1
chr2_-_230287442	1.343	NM_139072	DNER	delta/notch-like EGF repeat containing
chr13_+_87122778	1.310	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr11_+_66827494	1.306	NM_017857	SSH3	slingshot homolog 3 (Drosophila)
chr9_+_71848555	1.285		MAMDC2	MAM domain containing 2
chr11_-_16992524	1.273	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr7_-_84654106	1.271		SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr17_-_37144408	1.262	NM_001079870 NM_001079871 NM_177977	HAP1	huntingtin-associated protein 1
chr19_+_44266784	1.261	NM_001004318	PAPL	iron/zinc purple acid phosphatase-like protein
chr6_+_129245978	1.234	NM_000426 NM_001079823	LAMA2	laminin, alpha 2
chr6_+_133604203	1.233		EYA4	eyes absent homolog 4 (Drosophila)
chr3_-_49732062	1.224	NM_198722	AMIGO3	adhesion molecule with Ig-like domain 3
chr11_+_66827563	1.213		SSH3	slingshot homolog 3 (Drosophila)
chr4_-_4279516	1.211	NM_177998	OTOP1	otopetrin 1
chr19_+_49972965	1.208	NM_001130852 NM_012116	CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c
chr13_-_71338558	1.176		DACH1	dachshund homolog 1 (Drosophila)
chr11_+_7997366	1.171		TUB	tubby homolog (mouse)
chr6_+_124166767	1.164	NM_001040214 NM_153355	NKAIN2	Na+/K+ transporting ATPase interacting 2
chr3_-_42280442	1.164	NM_001174138	CCK	cholecystokinin
chr2_-_128155829	1.158	NM_001161404	LIMS2	LIM and senescent cell antigen-like domains 2
chrX_-_154341451	1.149	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr14_-_59001804	1.127	NM_022571	GPR135	G protein-coupled receptor 135
chr4_-_55686503	1.127	NM_002253	KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)
chr4_+_37569093	1.125	NM_015173	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_+_110916629	1.120		LAYN	layilin
chr14_+_62740878	1.118	NM_020663	RHOJ	ras homolog gene family, member J
chr7_-_72822471	1.111	NM_001306	CLDN3	claudin 3
chr14_+_73073570	1.102	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr19_-_50977485	1.085		DMPK	dystrophia myotonica-protein kinase
chr8_-_143692814	1.081	NM_015193	ARC	activity-regulated cytoskeleton-associated protein
chr5_+_113726203	1.075		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr8_-_17315386	1.074	NM_004686	MTMR7	myotubularin related protein 7
chr19_-_1083109	1.069	NM_001100122	SBNO2	strawberry notch homolog 2 (Drosophila)
chr1_-_199732323	1.067	NM_001193572	CSRP1	cysteine and glycine-rich protein 1
chr4_+_158216631	1.066	NM_000824 NM_001166061 NM_001166060	GLRB	glycine receptor, beta
chr2_+_106048543	1.065	NM_032411	C2orf40	chromosome 2 open reading frame 40
chr2_+_238060602	1.063	NM_001042467 NM_024101	MLPH	melanophilin
chr17_-_29930431	1.061	NM_207454	C17orf102	chromosome 17 open reading frame 102
chr7_-_27136876	1.057	NM_002141	HOXA4	homeobox A4
chr15_-_61680003	1.056		LOC100130855	hypothetical LOC100130855
chr20_-_61356247	1.054	NM_152864	NKAIN4	Na+/K+ transporting ATPase interacting 4
chr10_+_104667991	1.053	NM_017649 NM_199076 NM_199077	CNNM2	cyclin M2
chr3_-_30911156	1.049	NM_207359	GADL1	glutamate decarboxylase-like 1
chr4_+_7245218	1.049	NM_020777	SORCS2	sortilin-related VPS10 domain containing receptor 2
chr8_+_31616809	1.049	NM_013962	NRG1	neuregulin 1
chr2_-_47650973	1.048	NM_022055	KCNK12	potassium channel, subfamily K, member 12
chr14_+_99181232	1.030	NM_001127258 NM_032425	HHIPL1	HHIP-like 1
chr4_+_134292630	1.026		PCDH10	protocadherin 10
chr10_+_123913094	1.021	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr5_+_74197473	1.018		LOC441086	hypothetical LOC441086
chr2_-_133144950	1.009	NM_144586	LYPD1	LY6/PLAUR domain containing 1
chr8_+_35212505	1.006	NM_080872	UNC5D	unc-5 homolog D (C. elegans)
chr20_-_49852353	0.995	NM_020436	SALL4	sal-like 4 (Drosophila)
chr12_+_63504708	0.994		TBC1D30	TBC1 domain family, member 30
chr1_+_199519202	0.986	NM_000299 NM_001005337	PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)
chr12_+_51730101	0.986	NM_170754	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr11_-_117200618	0.982	NM_001127489 NM_001680	FXYD2	FXYD domain containing ion transport regulator 2
chr11_+_1812115	0.980	NM_138567	SYT8	synaptotagmin VIII
chr17_-_64108529	0.979	NM_017565	FAM20A	family with sequence similarity 20, member A
chr17_+_29931880	0.973	NM_207313	TMEM132E	transmembrane protein 132E
chr16_-_4105703	0.972		ADCY9	adenylate cyclase 9
chr12_+_63504618	0.968	NM_015279	TBC1D30	TBC1 domain family, member 30
chr4_-_85638410	0.967	NM_006168	NKX6-1	NK6 homeobox 1
chr22_+_44277354	0.966	NM_001996 NM_006485 NM_006486 NM_006487	FBLN1	fibulin 1
chr2_-_133144094	0.958		LYPD1	LY6/PLAUR domain containing 1
chr3_-_62836052	0.954	NM_003716 NM_183393 NM_183394	CADPS	Ca++-dependent secretion activator
chr9_+_132002692	0.947	NM_001128826	NCS1	neuronal calcium sensor 1
chr2_-_192767844	0.945	NM_016192	TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr14_+_37748031	0.940		SSTR1	somatostatin receptor 1
chr3_+_142253102	0.937		SPSB4	splA/ryanodine receptor domain and SOCS box containing 4
chr9_-_122731263	0.935	NM_001190945	TRAF1	TNF receptor-associated factor 1
chr4_+_185063421	0.935	NM_020225	STOX2	storkhead box 2
chr9_-_85342868	0.930	NM_174938	FRMD3	FERM domain containing 3
chrX_-_99551926	0.924	NM_001105243 NM_001184880 NM_020766	PCDH19	protocadherin 19
chr9_-_25668230	0.923		TUSC1	tumor suppressor candidate 1
chr13_+_95541093	0.920	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr12_-_14929991	0.920	NM_000900 NM_001190839	MGP	matrix Gla protein
chr3_+_185430910	0.918	NM_138345	VWA5B2	von Willebrand factor A domain containing 5B2
chr1_+_13782838	0.915	NM_006474 NM_198389	PDPN	podoplanin
chr7_-_32076985	0.907	NM_001191056 NM_001191057	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa
chr10_+_105026773	0.902	NM_032727	INA	internexin neuronal intermediate filament protein, alpha
chr10_+_123912930	0.898		TACC2	transforming, acidic coiled-coil containing protein 2
chr7_-_22363036	0.893	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr3_+_11171213	0.892	NM_001098212	HRH1	histamine receptor H1
chr2_-_19421852	0.885	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr11_-_86060812	0.884	NM_001014811	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chr8_-_22070208	0.882	NM_139278	LGI3	leucine-rich repeat LGI family, member 3
chr14_-_47213906	0.880	NM_001113498	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr13_+_48692472	0.879	NM_001507	MLNR	motilin receptor
chr8_-_17315171	0.877		MTMR7	myotubularin related protein 7
chr4_+_89597257	0.871	NM_016323	HERC5	hect domain and RLD 5
chr10_-_125841840	0.871	NM_014863 NM_015892	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_-_58370693	0.864	NM_001197221 NM_001197222	PDE4D	phosphodiesterase 4D, cAMP-specific
chr15_-_53996597	0.864	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr16_+_22733307	0.862	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr15_+_72620570	0.862	NM_006465	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr9_+_115957537	0.857		COL27A1	collagen, type XXVII, alpha 1
chr17_-_64108331	0.854		FAM20A	family with sequence similarity 20, member A
chr3_+_49034494	0.851		NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chrX_-_19815586	0.850	NM_031892	SH3KBP1	SH3-domain kinase binding protein 1
chr13_+_77170470	0.850	NM_001040153	SLAIN1	SLAIN motif family, member 1
chr4_-_1097313	0.850	NM_001131034 NM_001193318 NM_194439	RNF212	ring finger protein 212
chrX_+_12066505	0.847	NM_014728	FRMPD4	FERM and PDZ domain containing 4
chr6_+_137285071	0.845	NM_001008783	SLC35D3	solute carrier family 35, member D3
chr16_-_47201588	0.845	NM_153029	N4BP1	NEDD4 binding protein 1
chr10_+_105243724	0.843	NM_004210	NEURL	neuralized homolog (Drosophila)
chr11_+_72653197	0.833	NM_176796 NM_176797	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_-_199704773	0.823	NM_012396	PHLDA3	pleckstrin homology-like domain, family A, member 3
chr11_-_9069668	0.818	NM_001170690 NM_020974	SCUBE2	signal peptide, CUB domain, EGF-like 2
chr7_-_35192177	0.815		DPY19L2P1	dpy-19-like 2 pseudogene 1 (C. elegans)
chr17_+_4743645	0.815	NM_001145536	C17orf107	chromosome 17 open reading frame 107
chr5_-_136862317	0.812		SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr11_-_129803515	0.810		ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8
chrX_+_129133234	0.809	NM_004794	RAB33A	RAB33A, member RAS oncogene family
chr13_+_30378311	0.806	NM_032849	C13orf33	chromosome 13 open reading frame 33
chr11_-_74818858	0.797		KLHL35	kelch-like 35 (Drosophila)
chr14_-_103058568	0.797		CKB	creatine kinase, brain
chr7_-_11838260	0.794	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr14_-_60817621	0.793
chr4_+_93444572	0.791	NM_001510	GRID2	glutamate receptor, ionotropic, delta 2
chr19_-_50977592	0.791	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr11_-_102174032	0.785		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr7_+_55054416	0.785		EGFR	epidermal growth factor receptor
chr11_+_13940715	0.782		SPON1	spondin 1, extracellular matrix protein
chr15_-_76700563	0.782	NM_000743 NM_001166694	CHRNA3	cholinergic receptor, nicotinic, alpha 3
chr16_+_22732982	0.781		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_-_50977586	0.781		DMPK	dystrophia myotonica-protein kinase
chr3_-_191522886	0.780	NM_021101	CLDN1	claudin 1
chr2_+_10969513	0.780	NM_002236	KCNF1	potassium voltage-gated channel, subfamily F, member 1
chr1_-_48235148	0.778	NM_001194986	LOC388630	UPF0632 protein A
chr4_-_186934059	0.775	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr3_+_9826930	0.775		TTLL3	tubulin tyrosine ligase-like family, member 3
chr2_-_39040981	0.773		LOC375196	hypothetical LOC375196
chr8_-_109165012	0.773	NM_178565	RSPO2	R-spondin 2 homolog (Xenopus laevis)
chr6_+_37245860	0.770	NM_002648	PIM1	pim-1 oncogene
chr22_+_22652248	0.769	NM_000854	GSTT2 GSTT2B	glutathione S-transferase theta 2 glutathione S-transferase theta 2B (gene/pseudogene)
chr11_-_684842	0.767		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr3_+_190147633	0.766		TPRG1	tumor protein p63 regulated 1
chr14_-_37795290	0.762	NM_175060	CLEC14A	C-type lectin domain family 14, member A
chr4_+_119174211	0.761		NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr19_-_50964336	0.761	NM_175875	SIX5	SIX homeobox 5
chr11_-_86061003	0.760	NM_006680	ME3	malic enzyme 3, NADP(+)-dependent, mitochondrial
chr11_+_12355600	0.757	NM_018222	PARVA	parvin, alpha

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	6.16e-12	GO:0007275	multicellular organismal development
1.22	7.71e-11	GO:0032502	developmental process
1.38	1.50e-10	GO:0007399	nervous system development
1.24	3.76e-10	GO:0048856	anatomical structure development
1.25	7.18e-10	GO:0048731	system development
1.43	4.68e-08	GO:0048468	cell development
1.26	8.05e-07	GO:0030154	cell differentiation
1.25	1.32e-06	GO:0048869	cellular developmental process
1.46	1.72e-06	GO:0030182	neuron differentiation
1.40	2.27e-06	GO:0022008	neurogenesis
1.41	2.38e-06	GO:0048699	generation of neurons
1.30	2.51e-06	GO:0009653	anatomical structure morphogenesis
1.23	1.66e-04	GO:0048513	organ development
1.06	3.89e-04	GO:0009987	cellular process
1.43	5.24e-04	GO:0048666	neuron development
1.30	9.00e-04	GO:0010646	regulation of cell communication
1.33	1.48e-03	GO:0009888	tissue development
1.44	1.61e-03	GO:0007417	central nervous system development
1.23	2.48e-03	GO:0023051	regulation of signaling
1.30	2.54e-03	GO:0007154	cell communication
1.26	2.99e-03	GO:0051239	regulation of multicellular organismal process
1.14	3.85e-03	GO:0023052	signaling
1.54	4.06e-03	GO:0001501	skeletal system development
1.43	4.86e-03	GO:0031175	neuron projection development
1.54	6.65e-03	GO:0019932	second-messenger-mediated signaling
1.37	6.69e-03	GO:0030030	cell projection organization
1.94	8.07e-03	GO:0007202	activation of phospholipase C activity
1.43	9.67e-03	GO:0048812	neuron projection morphogenesis
1.41	9.87e-03	GO:0000904	cell morphogenesis involved in differentiation
1.44	9.91e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
1.09	1.04e-02	GO:0050794	regulation of cellular process
2.19	1.11e-02	GO:0043279	response to alkaloid
1.92	1.13e-02	GO:0010863	positive regulation of phospholipase C activity
1.35	1.28e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.43	1.77e-02	GO:0007409	axonogenesis
1.46	2.01e-02	GO:0090066	regulation of anatomical structure size
1.08	2.24e-02	GO:0065007	biological regulation
1.30	2.24e-02	GO:0051128	regulation of cellular component organization
1.83	2.68e-02	GO:0060541	respiratory system development
1.39	2.77e-02	GO:0048858	cell projection morphogenesis
1.34	3.67e-02	GO:0032989	cellular component morphogenesis
1.50	3.88e-02	GO:0031667	response to nutrient levels
1.84	3.99e-02	GO:0010518	positive regulation of phospholipase activity
1.16	4.03e-02	GO:0048519	negative regulation of biological process
1.19	4.27e-02	GO:0007166	cell surface receptor linked signaling pathway
1.22	4.61e-02	GO:0035556	intracellular signal transduction
1.38	4.65e-02	GO:0032990	cell part morphogenesis
1.61	4.91e-02	GO:0007584	response to nutrient
1.80	4.97e-02	GO:0060193	positive regulation of lipase activity

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.52	8.98e-05	GO:0031012	extracellular matrix
1.49	3.22e-03	GO:0005578	proteinaceous extracellular matrix
1.07	4.55e-03	GO:0005737	cytoplasm
1.21	4.25e-02	GO:0005887	integral to plasma membrane
1.15	4.65e-02	GO:0044459	plasma membrane part
1.20	4.98e-02	GO:0031226	intrinsic to plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.94	1.71e-02	GO:0005201	extracellular matrix structural constituent