Motif ID: NKX2-2,8.p2

Z-value: 1.935


Transcription factors associated with NKX2-2,8.p2:

Gene SymbolEntrez IDGene Name
NKX2-2 4821 NK2 homeobox 2
NKX2-8 26257 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-2chr20_-_21442663-0.572.6e-02Click!
NKX2-8chr14_-_36121536-0.553.4e-02Click!


Activity profile for motif NKX2-2,8.p2.

activity profile for motif NKX2-2,8.p2


Sorted Z-values histogram for motif NKX2-2,8.p2

Sorted Z-values for motif NKX2-2,8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-2,8.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_101115677 4.333 NM_002674
 PMCH
pro-melanin-concentrating hormone
chr3_-_122862391 2.989 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_122862447 2.796 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_37689903 2.459


chr11_-_128217550 2.056 NM_000220
 KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr9_+_115303527 2.051 NM_130795
 RGS3
regulator of G-protein signaling 3
chr11_+_117680504 1.918 NM_000733
 CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr17_-_35327318 1.796 NM_018530
 GSDMB
gasdermin B
chr10_+_97505398 1.696 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
 ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr1_+_61642287 1.639 NFIA
nuclear factor I/A
chr7_+_139175420 1.579 NM_001061
NM_001166253
NM_030984
 TBXAS1


thromboxane A synthase 1 (platelet)


chr1_+_111818111 1.550 NM_174896
 C1orf162
chromosome 1 open reading frame 162
chr21_-_14840506 1.522 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr3_+_188197029 1.506


chr3_-_153541468 1.506 NM_001123228
 TMEM14E
transmembrane protein 14E
chr2_+_102320148 1.497 NM_003856
 IL1RL1
interleukin 1 receptor-like 1
chr12_+_9033403 1.474 NM_005810
 KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr16_+_24475129 1.464 RBBP6
retinoblastoma binding protein 6
chr7_-_107667728 1.462 NM_001037132
 NRCAM
neuronal cell adhesion molecule
chr3_-_15814678 1.462 NM_001195098
 ANKRD28
ankyrin repeat domain 28

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.31 2.45e-02 GO:0007165 signal transduction
1.28 3.35e-02 GO:0023052 signaling
1.26 3.90e-02 GO:0051716 cellular response to stimulus
1.21 1.33e-02 GO:0050896 response to stimulus

Nothing significant found in compartment category.

Nothing significant found in function category.