Motif ID: NKX3-1.p2

Z-value: 1.287


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23596346-0.136.4e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_156628929 3.190 NM_014376
 CYFIP2
cytoplasmic FMR1 interacting protein 2
chr20_+_30160952 2.385 NM_014742
 TM9SF4
transmembrane 9 superfamily protein member 4
chr22_+_38652555 2.199 GRAP2
GRB2-related adaptor protein 2
chr19_-_56612653 2.128 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
 SIGLEC10






sialic acid binding Ig-like lectin 10






chr14_+_87541220 2.060 NM_003608
 GPR65
G protein-coupled receptor 65
chr6_+_132000134 2.046 NM_005021
 ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_53847937 1.812 RNF43
ring finger protein 43
chr17_+_71975224 1.637 NM_001088
 AANAT
aralkylamine N-acetyltransferase
chr6_-_52060327 1.577 NM_138694
NM_170724
 PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr20_-_52120710 1.549 NM_003657
 BCAS1
breast carcinoma amplified sequence 1
chr3_-_42892195 1.496 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr1_-_246869181 1.414 NM_001001827
 OR2T35
olfactory receptor, family 2, subfamily T, member 35
chr3_-_57209319 1.387 NM_003865
 HESX1
HESX homeobox 1
chr13_+_51496679 1.380 NM_021645
 ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr9_-_103237851 1.349 NM_000035
 ALDOB
aldolase B, fructose-bisphosphate
chr6_+_53043729 1.323 NM_012347
 FBXO9
F-box protein 9
chr9_+_4829763 1.314 RCL1
RNA terminal phosphate cyclase-like 1
chr6_+_30238961 1.303 NM_033229
 TRIM15
tripartite motif containing 15
chr20_+_43764068 1.268 NM_172005
 WFDC13
WAP four-disulfide core domain 13
chr2_+_228064531 1.236 AGFG1
ArfGAP with FG repeats 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
3.62 1.76e-19 GO:0007608 sensory perception of smell
3.41 5.94e-19 GO:0007606 sensory perception of chemical stimulus
2.41 7.69e-13 GO:0007600 sensory perception
2.01 1.75e-02 GO:0050776 regulation of immune response
1.80 4.75e-07 GO:0050877 neurological system process
1.80 2.06e-03 GO:0006952 defense response
1.69 5.42e-07 GO:0003008 system process
1.33 1.11e-06 GO:0032501 multicellular organismal process
1.25 1.30e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.52 9.95e-06 GO:0005576 extracellular region
1.35 3.34e-06 GO:0005886 plasma membrane
1.34 3.79e-06 GO:0071944 cell periphery
1.19 4.35e-02 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
14.14 2.64e-04 GO:0005132 interferon-alpha/beta receptor binding
3.86 3.17e-04 GO:0004867 serine-type endopeptidase inhibitor activity
3.74 9.39e-21 GO:0004984 olfactory receptor activity
2.57 4.69e-02 GO:0004866 endopeptidase inhibitor activity
2.56 3.38e-02 GO:0030414 peptidase inhibitor activity
2.42 3.04e-14 GO:0004930 G-protein coupled receptor activity
1.88 4.18e-09 GO:0004888 transmembrane receptor activity
1.75 3.21e-09 GO:0004872 receptor activity
1.60 2.25e-07 GO:0004871 signal transducer activity
1.60 2.25e-07 GO:0060089 molecular transducer activity