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Motif ID: NKX3-1.p2

Z-value: 1.287

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_156628929	3.190	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr20_+_30160952	2.385	NM_014742	TM9SF4	transmembrane 9 superfamily protein member 4
chr22_+_38652555	2.199		GRAP2	GRB2-related adaptor protein 2
chr19_-_56612653	2.128	NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_033130	SIGLEC10	sialic acid binding Ig-like lectin 10
chr14_+_87541220	2.060	NM_003608	GPR65	G protein-coupled receptor 65
chr6_+_132000134	2.046	NM_005021	ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_53847937	1.812		RNF43	ring finger protein 43
chr17_+_71975224	1.637	NM_001088	AANAT	aralkylamine N-acetyltransferase
chr6_-_52060327	1.577	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr20_-_52120710	1.549	NM_003657	BCAS1	breast carcinoma amplified sequence 1
chr3_-_42892195	1.496		CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr1_-_246869181	1.414	NM_001001827	OR2T35	olfactory receptor, family 2, subfamily T, member 35
chr3_-_57209319	1.387	NM_003865	HESX1	HESX homeobox 1
chr13_+_51496679	1.380	NM_021645	ALG11 UTP14C	asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr9_-_103237851	1.349	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chr6_+_53043729	1.323	NM_012347	FBXO9	F-box protein 9
chr9_+_4829763	1.314		RCL1	RNA terminal phosphate cyclase-like 1
chr6_+_30238961	1.303	NM_033229	TRIM15	tripartite motif containing 15
chr20_+_43764068	1.268	NM_172005	WFDC13	WAP four-disulfide core domain 13
chr2_+_228064531	1.236		AGFG1	ArfGAP with FG repeats 1
chr7_+_99654806	1.234	NM_024070	PVRIG	poliovirus receptor related immunoglobulin domain containing
chr1_+_246682699	1.230	NM_001004136	OR2T2	olfactory receptor, family 2, subfamily T, member 2
chr4_+_71418886	1.203	NM_212557	AMTN	amelotin
chr19_+_56671649	1.197	NM_001080405	CEACAM18	carcinoembryonic antigen-related cell adhesion molecule 18
chr2_-_207291364	1.196	NM_001093730	DYTN	dystrotelin
chr12_+_130004404	1.187	NM_198827	GPR133	G protein-coupled receptor 133
chr20_-_34707971	1.184	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr20_+_30161173	1.183		TM9SF4	transmembrane 9 superfamily protein member 4
chr16_+_82540172	1.176	NM_013370 NM_182980	OSGIN1	oxidative stress induced growth inhibitor 1
chr10_-_11614279	1.174	NM_001080491	USP6NL	USP6 N-terminal like
chr1_+_165565006	1.058		POU2F1	POU class 2 homeobox 1
chr14_-_24148658	1.049	NM_033423	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)
chr2_-_32344192	1.048	NM_021209	NLRC4	NLR family, CARD domain containing 4
chr12_+_91620749	1.047	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr3_-_152403636	1.036	NM_013308	GPR171	G protein-coupled receptor 171
chr12_+_55018925	1.033	NM_016584	IL23A	interleukin 23, alpha subunit p19
chr12_+_8167494	1.013	NM_016184 NM_194447 NM_194448 NM_194450	CLEC4A	C-type lectin domain family 4, member A
chr3_-_198784590	1.007	NM_203315	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr18_-_21184824	0.990
chr8_+_23157094	0.990	NM_152272	CHMP7	CHMP family, member 7
chr9_-_124981125	0.982		STRBP	spermatid perinuclear RNA binding protein
chr2_+_69974581	0.977	NM_006857	SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr7_+_141457977	0.958		LOC93432	maltase-glucoamylase-like pseudogene
chr1_+_246195157	0.942	NM_001004491	OR2AK2	olfactory receptor, family 2, subfamily AK, member 2
chr2_-_127817143	0.931	NM_006609	MAP3K2	mitogen-activated protein kinase kinase kinase 2
chr12_+_40117751	0.916	NM_013377	PDZRN4	PDZ domain containing ring finger 4
chr6_+_167445284	0.898	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr12_+_61645361	0.884		RPL14	ribosomal protein L14
chr15_+_97990705	0.876	NM_001130928	MEF2A	myocyte enhancer factor 2A
chrX_+_99726445	0.873	NM_022144	TNMD	tenomodulin
chr1_-_151630168	0.870	NM_002964	S100A8	S100 calcium binding protein A8
chr3_+_171183203	0.866		SEC62	SEC62 homolog (S. cerevisiae)
chr21_-_42659671	0.858	NM_003225	TFF1	trefoil factor 1
chr20_+_56919233	0.852		GNAS	GNAS complex locus
chr1_-_156954528	0.822	NM_001005327	OR6K3	olfactory receptor, family 6, subfamily K, member 3
chr1_+_158975662	0.817	NM_021181	SLAMF7	SLAM family member 7
chr12_+_100394787	0.816	NM_152323	SPIC	Spi-C transcription factor (Spi-1/PU.1 related)
chr17_+_23818922	0.810
chrX_+_71280758	0.786	NM_207422	FLJ44635	TPT1-like protein
chr9_-_35860316	0.763	NM_001004487	OR13J1	olfactory receptor, family 13, subfamily J, member 1
chr10_+_112334066	0.758		SMC3	structural maintenance of chromosomes 3
chr10_+_124660206	0.751	NM_001029888	FAM24A	family with sequence similarity 24, member A
chr8_+_24207524	0.740	NM_014265 NM_021777	ADAM28	ADAM metallopeptidase domain 28
chr4_+_17125885	0.739	NM_001079827	CLRN2	clarin 2
chr2_-_165259334	0.735		COBLL1	COBL-like 1
chr4_-_10295412	0.729	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr15_+_57691382	0.711		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr12_+_49155798	0.698		LARP4	La ribonucleoprotein domain family, member 4
chr1_-_158815850	0.694		CD84	CD84 molecule
chr20_+_12937616	0.693	NM_018327	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr14_+_38772870	0.692	NM_054024	MIA2	melanoma inhibitory activity 2
chr4_+_187385618	0.677	NM_000892	KLKB1	kallikrein B, plasma (Fletcher factor) 1
chr2_-_21106291	0.666		APOB	apolipoprotein B (including Ag(x) antigen)
chr4_+_186587537	0.661	NM_001114357	C4orf47	chromosome 4 open reading frame 47
chr3_+_85858321	0.639	NM_153184	CADM2	cell adhesion molecule 2
chr12_-_101835510	0.636	NM_000277	PAH	phenylalanine hydroxylase
chr5_-_179040580	0.634	NM_001164444	CBY3	chibby homolog 3 (Drosophila)
chr12_-_14982708	0.623	NM_152321	ERP27	endoplasmic reticulum protein 27
chr17_-_16816113	0.619	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr20_-_44612619	0.613	NM_080721	C20orf123	chromosome 20 open reading frame 123
chr6_-_138862271	0.611	NM_001144060	NHSL1	NHS-like 1
chr7_+_142723340	0.609	NM_000083	CLCN1	chloride channel 1, skeletal muscle
chr18_+_27210737	0.609	NM_001134453 NM_177986	DSG4	desmoglein 4
chr4_+_74520796	0.608	NM_001134	AFP	alpha-fetoprotein
chr4_+_88748704	0.603	NM_014208	DSPP	dentin sialophosphoprotein
chr1_+_57093030	0.603	NM_000562	C8A	complement component 8, alpha polypeptide
chr6_-_76259976	0.598	NM_015687	FILIP1	filamin A interacting protein 1
chr6_+_16251260	0.592		MYLIP	myosin regulatory light chain interacting protein
chr3_-_42892636	0.586	NM_004391	CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr17_-_39500512	0.585	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr6_-_138862273	0.582
chr16_-_88604029	0.577	NM_024043	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1
chr1_+_50348052	0.574		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr11_+_59804634	0.573	NM_148975	MS4A4A	membrane-spanning 4-domains, subfamily A, member 4
chr2_-_208736533	0.572	NM_014617	CRYGA	crystallin, gamma A
chr3_-_99236520	0.569	NM_001105580	GABRR3	gamma-aminobutyric acid (GABA) receptor, rho 3
chr8_-_17787342	0.567		FGL1	fibrinogen-like 1
chr12_-_86947276	0.567	NM_152589	C12orf50	chromosome 12 open reading frame 50
chr16_+_2195424	0.567	NM_022372	MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr20_-_31055892	0.557	NM_080675	SUN5	Sad1 and UNC84 domain containing 5
chr19_-_47638890	0.554	NM_198477	CXCL17	chemokine (C-X-C motif) ligand 17
chr4_+_166350620	0.548	NM_001161521 NM_001161522	KLHL2	kelch-like 2, Mayven (Drosophila)
chr7_-_36730525	0.543	NM_001177506 NM_001177507 NM_001637	AOAH	acyloxyacyl hydrolase (neutrophil)
chrX_-_135783496	0.540
chr1_-_229627412	0.539	NM_022051	EGLN1	egl nine homolog 1 (C. elegans)
chr4_+_1872150	0.537	NM_133334	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr14_-_74669864	0.537		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr6_-_25982418	0.527	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr1_+_205329206	0.519	NM_000716 NM_001017364 NM_001017367	C4BPB	complement component 4 binding protein, beta
chr1_+_559618	0.516
chr1_-_158815895	0.511	NM_001184879 NM_001184881 NM_001184882 NM_003874	CD84	CD84 molecule
chr5_-_150663519	0.508	NM_001145017 NM_181774	SLC36A3	solute carrier family 36 (proton/amino acid symporter), member 3
chr1_-_20374273	0.501	NM_001105572	PLA2G2C	phospholipase A2, group IIC
chr20_-_51633042	0.501	NM_006526	ZNF217	zinc finger protein 217
chr14_+_66901237	0.500		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr21_-_30460841	0.500	NM_012131	CLDN17	claudin 17
chr12_+_25096472	0.499	NM_006152	LRMP	lymphoid-restricted membrane protein
chr1_-_205012348	0.497	NM_000572	IL10	interleukin 10
chr14_+_38804226	0.497	NM_203354	CTAGE5	CTAGE family, member 5
chr4_+_89115862	0.491		SPP1	secreted phosphoprotein 1
chr9_+_130056513	0.488
chr6_+_158654464	0.486		TULP4	tubby like protein 4
chr5_+_67622242	0.475	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr15_+_57691272	0.471	NM_004751	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr8_-_17797127	0.462	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr4_-_123761615	0.460	NM_021803	IL21	interleukin 21
chr1_-_20318578	0.459	NM_012400	PLA2G2D	phospholipase A2, group IID
chr8_-_59575249	0.455	NM_000780	CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1
chr7_+_69869099	0.449		AUTS2	autism susceptibility candidate 2
chr19_-_3922032	0.449		DAPK3	death-associated protein kinase 3
chr14_+_20493467	0.448	NM_002934	RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
chr11_-_30558495	0.448	NM_001584	MPPED2	metallophosphoesterase domain containing 2
chr4_+_155703581	0.446	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr5_-_160044844	0.443		ATP10B	ATPase, class V, type 10B
chr17_-_61655915	0.442	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr14_+_94148466	0.434	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr3_-_120761092	0.430	NM_005191	CD80	CD80 molecule
chr17_-_64752550	0.430	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr20_+_43691797	0.428	NM_080753	WFDC10A	WAP four-disulfide core domain 10A
chr6_+_152053323	0.428	NM_001122742	ESR1	estrogen receptor 1
chr5_+_147672181	0.426	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr6_+_64344307	0.424		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr6_-_28294642	0.422		LOC222699	transducer of ERBB2, 2 pseudogene
chr11_-_55942283	0.418	NM_001004744	OR5R1	olfactory receptor, family 5, subfamily R, member 1
chr13_+_52500830	0.417	NM_006418	OLFM4	olfactomedin 4
chr10_-_69736600	0.416		PBLD	phenazine biosynthesis-like protein domain containing
chr6_-_155818728	0.416	NM_015718	NOX3	NADPH oxidase 3
chr3_+_153074118	0.414	NM_033050	SUCNR1	succinate receptor 1
chr14_+_88130482	0.413	NM_207662	ZC3H14	zinc finger CCCH-type containing 14
chr4_-_103464491	0.406	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr4_+_89115892	0.406		SPP1	secreted phosphoprotein 1
chr17_+_58440629	0.406	NM_025185	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr22_-_22426551	0.406	NM_013378	VPREB3	pre-B lymphocyte 3
chr1_+_66230977	0.404	NM_001037340	PDE4B	phosphodiesterase 4B, cAMP-specific
chr1_-_149681265	0.400	NM_207171	POGZ	pogo transposable element with ZNF domain
chr3_+_187866464	0.399	NM_000412	HRG	histidine-rich glycoprotein
chr2_-_191580567	0.397		STAT1	signal transducer and activator of transcription 1, 91kDa
chr1_-_47179681	0.395		CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11
chr11_+_58888460	0.391	NM_001004729	OR5AN1	olfactory receptor, family 5, subfamily AN, member 1
chr1_+_114295289	0.389	NM_198269	HIPK1	homeodomain interacting protein kinase 1
chr5_-_39238818	0.389		FYB	FYN binding protein
chr15_-_74941339	0.386	NM_001145923	SCAPER	S-phase cyclin A-associated protein in the ER
chr3_+_123279439	0.386	NM_006889	CD86	CD86 molecule
chr4_-_186969041	0.385	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chrX_-_131401319	0.384	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr18_-_22696532	0.383	NM_004028	AQP4	aquaporin 4
chr11_+_67133502	0.382		NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa
chr1_-_157014048	0.381	NM_001005278	OR6N2	olfactory receptor, family 6, subfamily N, member 2
chr14_-_101617680	0.381		HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr21_-_26175068	0.371		APP	amyloid beta (A4) precursor protein
chr19_-_14771947	0.369	NM_198944	OR7C1	olfactory receptor, family 7, subfamily C, member 1
chr20_+_17622319	0.369	NM_001159495	BANF2	barrier to autointegration factor 2
chr1_-_47179729	0.368	NM_000778	CYP4A11 CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 11 cytochrome P450, family 4, subfamily A, polypeptide 22
chr18_-_3209846	0.367		MYOM1	myomesin 1, 185kDa
chr3_-_156904690	0.364	NM_014996	PLCH1	phospholipase C, eta 1
chr2_-_20375497	0.364		PUM2	pumilio homolog 2 (Drosophila)
chr10_-_98021144	0.363	NM_001114094 NM_013314	BLNK	B-cell linker
chrX_+_105823723	0.361	NM_024539	RNF128	ring finger protein 128
chr5_+_180726874	0.358	NM_001005224 NM_001005221 NM_001005277	OR4F3 OR4F29 OR4F16	olfactory receptor, family 4, subfamily F, member 3 olfactory receptor, family 4, subfamily F, member 29 olfactory receptor, family 4, subfamily F, member 16
chr12_+_52126131	0.358		PRR13	proline rich 13
chr1_-_180822686	0.356	NM_021133	RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr9_+_126158935	0.355
chr16_+_21603250	0.354	NM_001161683	OTOA	otoancorin
chr17_-_5078773	0.354	NM_207103	C17orf87	chromosome 17 open reading frame 87
chr6_+_158654890	0.352
chr1_+_151051070	0.352	NM_178349	LCE1B	late cornified envelope 1B
chr12_+_111047676	0.351	NM_001143906 NM_006700	TRAFD1	TRAF-type zinc finger domain containing 1
chrX_+_38096679	0.350	NM_000531	OTC	ornithine carbamoyltransferase
chr12_+_45896511	0.349		FAM113B	family with sequence similarity 113, member B
chr11_+_55335418	0.347	NM_001004738	OR5L1	olfactory receptor, family 5, subfamily L, member 1
chr18_-_22699650	0.347	NM_001650	AQP4	aquaporin 4
chr2_+_24660849	0.346	NM_003743 NM_147223 NM_147233	NCOA1	nuclear receptor coactivator 1
chr11_+_55362802	0.345	NM_001005496	OR5D16	olfactory receptor, family 5, subfamily D, member 16
chr8_-_124818754	0.344	NM_001003954 NM_004306	ANXA13	annexin A13
chr2_+_169465995	0.342	NM_001081686 NM_021176	G6PC2	glucose-6-phosphatase, catalytic, 2
chr4_+_75393053	0.341	NM_001013442	EPGN	epithelial mitogen homolog (mouse)
chr14_+_22859236	0.341	NM_004643	PABPN1	poly(A) binding protein, nuclear 1
chr14_+_23844269	0.341
chr6_-_137536412	0.340	NM_052962 NM_181309 NM_181310	IL22RA2	interleukin 22 receptor, alpha 2
chr9_-_21218132	0.336	NM_021268	IFNA17	interferon, alpha 17

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.62	1.76e-19	GO:0007608	sensory perception of smell
3.41	5.94e-19	GO:0007606	sensory perception of chemical stimulus
2.41	7.69e-13	GO:0007600	sensory perception
1.80	4.75e-07	GO:0050877	neurological system process
1.69	5.42e-07	GO:0003008	system process
1.33	1.11e-06	GO:0032501	multicellular organismal process
1.25	1.30e-04	GO:0050896	response to stimulus
1.80	2.06e-03	GO:0006952	defense response
2.01	1.75e-02	GO:0050776	regulation of immune response

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.35	3.34e-06	GO:0005886	plasma membrane
1.34	3.79e-06	GO:0071944	cell periphery
1.52	9.95e-06	GO:0005576	extracellular region
1.19	4.35e-02	GO:0031224	intrinsic to membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.74	9.39e-21	GO:0004984	olfactory receptor activity
2.42	3.04e-14	GO:0004930	G-protein coupled receptor activity
1.75	3.21e-09	GO:0004872	receptor activity
1.88	4.18e-09	GO:0004888	transmembrane receptor activity
1.60	2.25e-07	GO:0004871	signal transducer activity
1.60	2.25e-07	GO:0060089	molecular transducer activity
14.14	2.64e-04	GO:0005132	interferon-alpha/beta receptor binding
3.86	3.17e-04	GO:0004867	serine-type endopeptidase inhibitor activity
2.56	3.38e-02	GO:0030414	peptidase inhibitor activity
2.57	4.69e-02	GO:0004866	endopeptidase inhibitor activity