Motif ID: NKX3-2.p2

Z-value: 1.220


Transcription factors associated with NKX3-2.p2:

Gene SymbolEntrez IDGene Name
NKX3-2 579 NK3 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-2chr4_-_13155135-0.253.7e-01Click!


Activity profile for motif NKX3-2.p2.

activity profile for motif NKX3-2.p2


Sorted Z-values histogram for motif NKX3-2.p2

Sorted Z-values for motif NKX3-2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_82163568 1.468 C10orf58
chromosome 10 open reading frame 58
chr2_+_228386800 0.918 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr10_-_123343761 0.861 NM_001144916
FGFR2
fibroblast growth factor receptor 2
chr8_-_122722674 0.805 NM_005328
HAS2
hyaluronan synthase 2
chr6_-_112001590 0.751 NM_001164282
TRAF3IP2
TRAF3 interacting protein 2
chr16_-_28130201 0.690 XPO6
exportin 6
chr10_-_5436781 0.683 NM_001171864
NM_024803
TUBAL3

tubulin, alpha-like 3

chr2_-_148495642 0.627 NM_181742
ORC4
origin recognition complex, subunit 4
chr3_+_69216747 0.619 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_46418786 0.604 TSPAN1
tetraspanin 1
chr17_+_71154240 0.581 NM_001162997
LOC100130933
hypothetical protein LOC100130933
chr12_-_122155998 0.581 PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr1_+_35507197 0.575 ZMYM4
zinc finger, MYM-type 4
chr2_+_64540843 0.574 HSPC159
galectin-related protein
chr1_-_24311212 0.571 NM_152372
MYOM3
myomesin family, member 3
chr9_-_33455191 0.550 NOL6
nucleolar protein family 6 (RNA-associated)
chr12_+_32578513 0.547 FGD4
FYVE, RhoGEF and PH domain containing 4
chr20_-_1420004 0.506 SIRPB2
signal-regulatory protein beta 2
chr14_-_22840249 0.503


chr20_+_19903778 0.498 RIN2
Ras and Rab interactor 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.56 8.83e-03 GO:0016568 chromatin modification
1.47 1.83e-02 GO:0006325 chromatin organization
1.39 4.52e-02 GO:0051276 chromosome organization
1.23 1.65e-04 GO:0044267 cellular protein metabolic process
1.23 7.03e-03 GO:0043412 macromolecule modification
1.23 1.66e-02 GO:0006464 protein modification process
1.23 4.35e-02 GO:0006996 organelle organization
1.20 3.70e-08 GO:0044260 cellular macromolecule metabolic process
1.18 8.63e-03 GO:0019538 protein metabolic process
1.17 1.46e-06 GO:0043170 macromolecule metabolic process
1.13 3.62e-05 GO:0044237 cellular metabolic process
1.12 3.27e-05 GO:0008152 metabolic process
1.12 2.90e-04 GO:0044238 primary metabolic process
1.08 4.53e-06 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
2.40 6.50e-03 GO:0034708 methyltransferase complex
2.40 6.50e-03 GO:0035097 histone methyltransferase complex
1.20 2.06e-04 GO:0043228 non-membrane-bounded organelle
1.20 2.06e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.20 2.05e-03 GO:0031974 membrane-enclosed lumen
1.19 4.51e-03 GO:0043233 organelle lumen
1.19 5.25e-03 GO:0070013 intracellular organelle lumen
1.19 3.91e-02 GO:0031981 nuclear lumen
1.16 6.74e-08 GO:0044446 intracellular organelle part
1.15 1.72e-07 GO:0044422 organelle part
1.14 1.97e-02 GO:0032991 macromolecular complex
1.13 3.84e-05 GO:0044444 cytoplasmic part
1.12 1.41e-03 GO:0005634 nucleus
1.11 9.64e-10 GO:0043229 intracellular organelle
1.11 2.32e-08 GO:0043231 intracellular membrane-bounded organelle
1.11 3.60e-08 GO:0043227 membrane-bounded organelle
1.11 9.65e-08 GO:0005737 cytoplasm
1.10 1.67e-09 GO:0043226 organelle
1.09 1.29e-12 GO:0005622 intracellular
1.09 7.52e-12 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.31 4.28e-02 GO:0003723 RNA binding
1.14 8.82e-10 GO:0005515 protein binding
1.07 3.52e-06 GO:0005488 binding