Motif ID: NKX6-1,2.p2

Z-value: 1.623


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-1chr4_-_856384100.243.8e-01Click!
NKX6-2chr10_-_1344494670.194.9e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_17861266 4.129 NM_001105569
MSGN1
mesogenin 1
chr20_+_19863716 3.210 RIN2
Ras and Rab interactor 2
chr11_+_7574992 2.662 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr4_-_152368492 2.517 SH3D19
SH3 domain containing 19
chr12_-_28016182 2.435 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr2_+_218698980 2.382 NM_001557
CXCR2
chemokine (C-X-C motif) receptor 2
chr4_+_75393053 2.348 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr3_-_143230124 2.290 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr6_+_47774247 2.005 NM_153838
GPR115
G protein-coupled receptor 115
chr10_-_90601655 1.912 NM_144590
ANKRD22
ankyrin repeat domain 22
chr4_-_77147625 1.889 NM_002416
CXCL9
chemokine (C-X-C motif) ligand 9
chr22_-_25291268 1.832 NM_001008566
TPST2
tyrosylprotein sulfotransferase 2
chr11_-_128399218 1.815 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_+_185064654 1.746 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr21_-_35343065 1.633 RUNX1
runt-related transcription factor 1
chr12_-_6103945 1.625 NM_000552
VWF
von Willebrand factor
chr13_-_35327798 1.624 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr12_+_48443232 1.606 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr1_-_31251315 1.603 PUM1
pumilio homolog 1 (Drosophila)
chr6_-_32447626 1.558 NM_006781
C6orf10
chromosome 6 open reading frame 10

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.06 1.76e-02 GO:0051707 response to other organism
1.68 4.94e-02 GO:0006952 defense response
1.44 3.99e-02 GO:0007166 cell surface receptor linked signaling pathway
1.21 1.39e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.55 1.81e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.34 3.45e-02 GO:0005125 cytokine activity
1.59 9.34e-03 GO:0005102 receptor binding