Motif ID: NR1H4.p2

Z-value: 1.845


Transcription factors associated with NR1H4.p2:

Gene SymbolEntrez IDGene Name
NR1H4 9971 nuclear receptor subfamily 1, group H, member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR1H4chr12_+_993916810.312.7e-01Click!


Activity profile for motif NR1H4.p2.

activity profile for motif NR1H4.p2


Sorted Z-values histogram for motif NR1H4.p2

Sorted Z-values for motif NR1H4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR1H4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_27113018 3.613 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr6_+_31731647 3.262 NM_019101
APOM
apolipoprotein M
chr8_+_145692916 3.155 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr17_+_7474177 3.084 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr6_+_31731667 3.071 APOM
apolipoprotein M
chr17_+_7474128 3.051 SHBG
sex hormone-binding globulin
chr1_-_25619863 2.782 NM_020485
NM_138616
NM_138617
NM_138618
RHCE



RHD
Rh blood group, CcEe antigens



Rh blood group, D antigen
chr11_+_61389756 2.760 FADS2
fatty acid desaturase 2
chr1_+_25471470 2.650 NM_001127691
NM_016124
RHD

Rh blood group, D antigen

chr12_+_56802 2.636 NM_015232
IQSEC3
IQ motif and Sec7 domain 3
chr1_+_160618143 2.599 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr16_+_25135783 2.494 NM_001169
AQP8
aquaporin 8
chr22_+_19651446 2.469 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr11_-_6418705 2.448 NM_000613
HPX
hemopexin
chr20_-_43889339 2.428 NM_003279
TNNC2
troponin C type 2 (fast)
chr1_-_180622083 2.268 GLUL
glutamate-ammonia ligase
chr2_+_27225362 2.133 NM_175769
TCF23
transcription factor 23
chr1_+_152560179 2.066 NM_080429
AQP10
aquaporin 10
chr15_+_63124760 2.025 NM_178859
OSTBETA
organic solute transporter beta
chr3_+_50291521 2.023 NM_153215
C3orf45
chromosome 3 open reading frame 45
chr11_-_46674233 2.016 ARHGAP1
Rho GTPase activating protein 1
chr20_-_3097070 1.895 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr14_-_23623657 1.825 NM_006177
NRL
neural retina leucine zipper
chr17_+_18796202 1.764 NM_001042450
NM_152351
SLC5A10

solute carrier family 5 (sodium/glucose cotransporter), member 10

chr2_-_178645718 1.762 NM_016953
PDE11A
phosphodiesterase 11A
chr17_-_43390108 1.734 NM_024320
PRR15L
proline rich 15-like
chr7_+_100037817 1.697 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr1_+_559618 1.654


chr3_+_52803823 1.631 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr3_-_127719283 1.612 NM_001165974
NM_144639
UROC1

urocanase domain containing 1

chrX_-_153903963 1.587 NM_000132
F8
coagulation factor VIII, procoagulant component
chr19_+_40299058 1.584 FXYD3
FXYD domain containing ion transport regulator 3
chr2_-_73723001 1.581 NM_003960
NAT8
N-acetyltransferase 8 (GCN5-related, putative)
chr12_+_68028407 1.536 LYZ
lysozyme
chr12_-_7172641 1.514 NM_031491
RBP5
retinol binding protein 5, cellular
chr19_-_56585603 1.481 NM_001193623
LOC147646
hypothetical protein LOC147646
chr11_-_64459910 1.474 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr1_+_158603480 1.425 NM_005598
NHLH1
nescient helix loop helix 1
chr1_-_150070849 1.401 NM_005060
RORC
RAR-related orphan receptor C
chr20_+_57027703 1.394 NM_030773
TUBB1
tubulin, beta 1
chr19_-_54350457 1.365 NM_002152
HRC
histidine rich calcium binding protein
chr7_+_134567270 1.356 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr16_+_56259657 1.334 NM_170776
GPR97
G protein-coupled receptor 97
chr3_-_129777618 1.317 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr16_+_24765052 1.313 NM_052944
SLC5A11
solute carrier family 5 (sodium/glucose cotransporter), member 11
chr8_-_13018123 1.311 NM_001164271
DLC1
deleted in liver cancer 1
chr1_-_180621272 1.307 GLUL
glutamate-ammonia ligase
chr3_+_188043156 1.297 NM_001177800
NM_004797
ADIPOQ

adiponectin, C1Q and collagen domain containing

chr12_+_56299959 1.296 NM_133489
SLC26A10
solute carrier family 26, member 10
chr14_+_54238581 1.293 SAMD4A
sterile alpha motif domain containing 4A
chr19_+_810673 1.273 CFD
complement factor D (adipsin)
chr11_-_64133908 1.266


chr19_+_55398680 1.251 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr2_+_218929822 1.246 NM_198559
C2orf62
chromosome 2 open reading frame 62
chr19_-_63556632 1.240 NM_130786
A1BG
alpha-1-B glycoprotein
chr22_+_43451351 1.240 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr17_-_77092831 1.221 ACTG1
actin, gamma 1
chr2_-_85490997 1.213 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr3_+_188043172 1.209 ADIPOQ
adiponectin, C1Q and collagen domain containing
chr2_+_108271526 1.182 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr2_-_105381855 1.182 NM_001039492
NM_001450
NM_201555
FHL2


four and a half LIM domains 2


chr19_-_47638890 1.110 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr1_+_54880014 1.099 NM_001039464
HEATR8-TTC4
HEATR8
HEATR8-TTC4 read-through transcript
HEAT repeat containing 8
chr17_-_24426752 1.098 NM_004740
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr3_-_49701085 1.094 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr1_+_149221122 1.092 NM_003568
ANXA9
annexin A9
chr22_-_22304486 1.066 NM_016449
C22orf43
chromosome 22 open reading frame 43
chr22_-_29231597 1.049 NM_001161368
NM_174977
SEC14L4

SEC14-like 4 (S. cerevisiae)

chr11_-_64368616 1.045 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr17_+_37247568 1.040 NM_152467
KLHL10
kelch-like 10 (Drosophila)
chr3_-_50315983 1.033 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chrX_+_106336517 1.031 NM_001169154
NM_173494
CXorf41

chromosome X open reading frame 41

chr22_+_23329113 1.031 NM_001032364
NM_005265
GGT1

gamma-glutamyltransferase 1

chr19_+_15644885 1.030 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr19_+_810658 1.028 NM_001928
CFD
complement factor D (adipsin)
chr22_+_43451600 1.012 PRR5
proline rich 5 (renal)
chr3_-_197726587 1.005 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr3_-_15349086 1.005 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr6_+_44234525 1.004 NM_007058
CAPN11
calpain 11
chr1_-_172153024 0.994 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr7_+_128099581 0.992 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr8_-_37576515 0.978 LOC157860
hypothetical protein LOC157860
chr15_-_38185578 0.976 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr22_+_18085891 0.976 SEPT5
septin 5
chr3_-_52463070 0.976 NM_003280
TNNC1
troponin C type 1 (slow)
chr1_+_33003814 0.974 NM_001198972
NM_001198973
KIAA1522

KIAA1522

chr1_+_15941503 0.967 NM_001013641
TMEM82
transmembrane protein 82
chr16_+_87765661 0.965 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr19_-_56567602 0.961 NM_005601
NKG7
natural killer cell group 7 sequence
chr1_-_47468029 0.956 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr20_-_54534387 0.953 NM_080615
GCNT7
glucosaminyl (N-acetyl) transferase family member 7
chr1_+_29086156 0.950 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr16_+_55373241 0.940 NUP93
nucleoporin 93kDa
chr1_+_85819004 0.934 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr17_-_3651236 0.930 NM_002208
ITGAE
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
chr1_+_148496792 0.929 NM_012113
CA14
carbonic anhydrase XIV
chr22_+_18085990 0.923 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr17_-_51164443 0.908 NM_001099640
TMEM100
transmembrane protein 100
chr19_+_10424581 0.880 NM_006202
PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_+_18588050 0.878 NM_031456
FBXW10
CDRT1
F-box and WD repeat domain containing 10
CMT1A duplicated region transcript 1
chr16_+_8722068 0.863 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr2_+_220087135 0.860 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr11_-_116168316 0.859 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr2_+_176724358 0.854 NM_014621
HOXD4
homeobox D4
chr6_-_32268267 0.848 GPSM3
G-protein signaling modulator 3
chr1_+_33003847 0.844 KIAA1522
KIAA1522
chr11_-_113082233 0.842 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr12_+_52105131 0.839 AMHR2
anti-Mullerian hormone receptor, type II
chr1_-_205186330 0.836 NM_002644
PIGR
polymeric immunoglobulin receptor
chr4_-_69852090 0.828 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_12046020 0.826 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr1_+_29086206 0.821 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr1_-_143708467 0.819 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr16_-_73012740 0.812 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr3_-_15348811 0.812 SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr1_+_6537924 0.808 NM_138697
NM_177540
TAS1R1

taste receptor, type 1, member 1

chr19_-_40317829 0.808 NM_139284
LGI4
leucine-rich repeat LGI family, member 4
chr8_+_110443881 0.807 NM_177531
PKHD1L1
polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1
chr11_+_118561375 0.804 NM_001168468
NM_024791
PDZD3

PDZ domain containing 3

chr17_+_37942034 0.800


chr16_+_30102426 0.793 CORO1A
coronin, actin binding protein, 1A
chr22_-_20637188 0.792 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr12_+_107797985 0.791 NM_001917
DAO
D-amino-acid oxidase
chr6_+_112775224 0.779 NM_001013734
RFPL4B
ret finger protein-like 4B
chr11_-_5232480 0.774 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr1_-_16411690 0.770 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr1_-_11029737 0.762 NM_006610
NM_139208
MASP2

mannan-binding lectin serine peptidase 2

chr2_+_97696462 0.761 NM_001079
ZAP70
zeta-chain (TCR) associated protein kinase 70kDa
chr17_-_77421980 0.759 NM_001185077
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr1_+_114295289 0.758 NM_198269
HIPK1
homeodomain interacting protein kinase 1
chr1_+_203179976 0.754 NM_001160331
NFASC
neurofascin
chr16_+_29892714 0.753 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr1_+_116727514 0.752 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chrX_+_128966844 0.747 NM_021946
BCORL1
BCL6 corepressor-like 1
chr6_+_44302973 0.747 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr2_-_85490984 0.746 CAPG
capping protein (actin filament), gelsolin-like
chr22_-_20637212 0.742 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr17_-_42250961 0.741 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr10_-_75304225 0.739 NM_001222
NM_172169
NM_172171
NM_172173
NM_172170
CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr10_-_101831579 0.735 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr17_+_71097147 0.734 MYO15B
myosin XVB pseudogene
chr11_+_61276576 0.731 NM_001127392
C11orf9
chromosome 11 open reading frame 9
chr13_-_99422163 0.731 NM_033132
ZIC5
Zic family member 5 (odd-paired homolog, Drosophila)
chr2_+_176724583 0.731


chr19_-_18246166 0.726 NM_001145304
NM_001145305
NM_025249
KIAA1683


KIAA1683


chr3_-_180460372 0.723 NM_171829
KCNMB3
potassium large conductance calcium-activated channel, subfamily M beta member 3
chr18_+_75967902 0.718 NM_014913
ADNP2
ADNP homeobox 2
chr18_-_26935883 0.717 NM_004949
NM_024422
DSC2

desmocollin 2

chr6_-_2785682 0.715 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr20_-_3592045 0.704 NM_022139
NM_145762
GFRA4

GDNF family receptor alpha 4

chr17_-_43283529 0.703 SP6
Sp6 transcription factor
chr17_+_2627099 0.703 RAP1GAP2
RAP1 GTPase activating protein 2
chr20_+_36643251 0.703 NM_001018082
ADIG
adipogenin
chr11_+_67007155 0.699 AIP
aryl hydrocarbon receptor interacting protein
chr11_+_64114857 0.697 NM_144585
NM_153378
SLC22A12

solute carrier family 22 (organic anion/urate transporter), member 12

chr14_-_69333624 0.693 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr3_+_48388712 0.692 NM_001159927
NM_001159929
NM_207102
FBXW12


F-box and WD repeat domain containing 12


chr6_-_27988152 0.691 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr1_+_148020869 0.690 NM_000566
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr7_+_44045202 0.690 FLJ35390
hypothetical LOC255031
chr6_-_32184975 0.689 NM_019105
TNXB
tenascin XB
chr17_-_39500512 0.687 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chrX_-_106033202 0.684 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr6_+_43373972 0.682 NM_006672
NM_153320
SLC22A7

solute carrier family 22 (organic anion transporter), member 7

chr15_+_70734091 0.681 NM_018652
GOLGA6A
GOLGA6B
golgin A6 family, member A
golgin A6 family, member B
chr4_+_74500748 0.681 ALB
albumin
chr9_-_103237851 0.678 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chrX_-_70243362 0.671 NM_001025265
CXorf65
chromosome X open reading frame 65
chr1_+_15675182 0.669 NM_015849
CELA2B
chymotrypsin-like elastase family, member 2B
chr11_+_75106512 0.668 NM_025098
MOGAT2
monoacylglycerol O-acyltransferase 2
chr16_-_70080678 0.667 NM_006961
ZNF19
zinc finger protein 19
chr14_-_23968570 0.665 NM_001039771
CBLN3
cerebellin 3 precursor
chr10_+_71060008 0.665 NM_145306
C10orf35
chromosome 10 open reading frame 35
chr6_+_24465109 0.661 NM_181337
KAAG1
kidney associated antigen 1
chr17_+_75319476 0.659 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr17_+_61729193 0.658 PRKCA
protein kinase C, alpha
chr11_+_63030131 0.655 LGALS12
lectin, galactoside-binding, soluble, 12
chr20_-_34921689 0.655 NM_199181
KIAA0889
KIAA0889
chr5_+_131621276 0.647 PDLIM4
PDZ and LIM domain 4
chr1_-_109386112 0.645 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chr7_+_12595672 0.643 NM_033128
SCIN
scinderin
chr17_+_42641426 0.641 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_+_149877955 0.639 SNX27
sorting nexin family member 27
chr7_-_44547382 0.637 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr2_+_178893216 0.637 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr1_-_2129031 0.635 NM_001146310
C1orf86
chromosome 1 open reading frame 86
chr1_-_59020875 0.634 JUN
jun proto-oncogene
chr1_-_148174722 0.632 NM_181873
MTMR11
myotubularin related protein 11
chr11_+_74539679 0.631 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr7_+_36395913 0.630 NM_018685
ANLN
anillin, actin binding protein
chr12_+_52103905 0.630 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr11_-_56846246 0.624 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr22_+_23309717 0.623 NM_013430
GGT1
gamma-glutamyltransferase 1
chr17_+_77910411 0.618 NM_207459
TEX19
testis expressed 19
chr9_-_103185621 0.613 NM_001127610
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr1_+_26433200 0.613 NM_022778
CCDC21
coiled-coil domain containing 21
chr16_+_1979959 0.613 NM_004209
SYNGR3
synaptogyrin 3
chr17_-_77386156 0.612 DYSFIP1
dysferlin interacting protein 1
chr5_+_131621287 0.605 PDLIM4
PDZ and LIM domain 4
chr17_-_24062998 0.605 NM_152465
PROCA1
protein interacting with cyclin A1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.02 1.64e-02 GO:0010035 response to inorganic substance
2.24 4.49e-02 GO:0010038 response to metal ion

Nothing significant found in compartment category.

Nothing significant found in function category.