Motif ID: NR5A1,2.p2

Z-value: 2.394


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR5A1chr9_-_1263095100.667.9e-03Click!
NR5A2chr1_+_198278339-0.117.1e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_37576515 3.743 LOC157860
hypothetical protein LOC157860
chr15_+_60838053 3.227 TLN2
talin 2
chr5_+_176449156 2.931 NM_022963
 FGFR4
fibroblast growth factor receptor 4
chr7_+_29486010 2.889 NM_001039936
 CHN2
chimerin (chimaerin) 2
chr22_+_19239221 2.573 MED15
mediator complex subunit 15
chr3_+_50281582 2.481 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_-_120781002 2.388 NM_002150
 HPD
4-hydroxyphenylpyruvate dioxygenase
chr1_+_46413335 2.331 NM_005727
 TSPAN1
tetraspanin 1
chr16_-_65510230 2.314 NM_004062
 CDH16
cadherin 16, KSP-cadherin
chr17_-_45626967 2.252


chr3_-_124821868 2.242 MYLK
myosin light chain kinase
chr17_+_37247568 2.196 NM_152467
 KLHL10
kelch-like 10 (Drosophila)
chr11_-_118740069 2.117 NM_171997
 USP2
ubiquitin specific peptidase 2
chr3_-_49435114 2.077 NM_000481
NM_001164710
NM_001164711
NM_001164712
 AMT



aminomethyltransferase



chr20_-_43889339 2.027 NM_003279
 TNNC2
troponin C type 2 (fast)
chr7_+_30758269 2.002 NM_006774
 INMT-FAM188B
INMT
INMT-FAM188B read-through transcript
indolethylamine N-methyltransferase
chr10_+_44726635 1.960 NM_001123376
 TMEM72
transmembrane protein 72
chr17_+_1586034 1.949 WDR81
WD repeat domain 81
chr17_-_35774467 1.937 NM_152219
 GJD3
gap junction protein, delta 3, 31.9kDa
chr1_-_169888373 1.875 NM_000261
 MYOC
myocilin, trabecular meshwork inducible glucocorticoid response

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.05 1.56e-03 GO:0007517 muscle organ development
1.99 2.63e-02 GO:0006936 muscle contraction
1.97 1.86e-02 GO:0003012 muscle system process
1.96 7.53e-03 GO:0010817 regulation of hormone levels
1.58 2.68e-02 GO:0006066 alcohol metabolic process
1.27 2.49e-03 GO:0065008 regulation of biological quality
1.16 4.56e-04 GO:0032501 multicellular organismal process
1.07 2.77e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
5.77 7.63e-04 GO:0005833 hemoglobin complex
2.38 7.46e-05 GO:0043292 contractile fiber
2.38 2.13e-04 GO:0044449 contractile fiber part
2.32 4.27e-04 GO:0030016 myofibril
2.27 5.48e-03 GO:0030017 sarcomere
1.61 4.60e-02 GO:0015629 actin cytoskeleton
1.42 2.23e-03 GO:0005626 insoluble fraction
1.42 4.66e-02 GO:0030054 cell junction
1.40 5.94e-03 GO:0005624 membrane fraction
1.32 1.41e-02 GO:0000267 cell fraction
1.22 2.44e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
6.59 2.62e-02 GO:0051393 alpha-actinin binding
5.32 3.96e-03 GO:0005344 oxygen transporter activity