Motif ID: NRF1.p2

Z-value: 5.574


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290387650.486.9e-02Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_64301807 4.324 NM_001178031
 SF1
splicing factor 1
chr19_-_51097694 4.069 NM_001012643
 MYPOP
Myb-related transcription factor, partner of profilin
chr1_+_32251988 3.822 NM_006559
 KHDRBS1
KH domain containing, RNA binding, signal transduction associated 1
chr2_-_33677798 3.745 NM_015475
 FAM98A
family with sequence similarity 98, member A
chr4_-_56107725 3.100 NM_004898
 CLOCK
clock homolog (mouse)
chr6_-_163754903 2.998 LOC100526820
hypothetical LOC100526820
chr6_-_33787413 2.928 C6orf125
chromosome 6 open reading frame 125
chr14_+_22633728 2.909 C14orf119
chromosome 14 open reading frame 119
chr21_+_33619147 2.851 IFNAR1
interferon (alpha, beta and omega) receptor 1
chr17_-_44794325 2.781 NM_001145365
NM_014897
 ZNF652

zinc finger protein 652

chr6_-_33787479 2.542 NM_032340
 C6orf125
chromosome 6 open reading frame 125
chr17_-_35510074 2.510 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr21_+_33066281 2.509 C21orf49
chromosome 21 open reading frame 49
chr11_+_64785888 2.371 NM_002689
 POLA2
polymerase (DNA directed), alpha 2 (70kD subunit)
chr12_-_123023052 2.348 NM_025140
 CCDC92
coiled-coil domain containing 92
chr3_+_43303005 2.332 NM_001100594
NM_017719
 SNRK

SNF related kinase

chr1_-_19409328 2.331 NM_020765
 UBR4
ubiquitin protein ligase E3 component n-recognin 4
chr1_-_16174859 2.330 NM_003443
 ZBTB17
zinc finger and BTB domain containing 17
chr3_+_49424642 2.329 NM_022171
 TCTA
T-cell leukemia translocation altered gene
chr2_-_197499584 2.298 NM_024989
 PGAP1
post-GPI attachment to proteins 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 100 entries
enrichment   p-value GO term description
3.08 2.14e-05 GO:0006302 double-strand break repair
3.04 9.68e-05 GO:0006405 RNA export from nucleus
3.03 6.33e-04 GO:0006406 mRNA export from nucleus
2.81 8.76e-05 GO:0051168 nuclear export
2.63 1.29e-02 GO:0006200 ATP catabolic process
2.55 9.11e-05 GO:0051028 mRNA transport
2.51 1.35e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
2.48 8.23e-06 GO:0006310 DNA recombination
2.46 1.20e-04 GO:0050657 nucleic acid transport
2.46 1.20e-04 GO:0050658 RNA transport
2.46 1.20e-04 GO:0051236 establishment of RNA localization
2.44 1.04e-04 GO:0006403 RNA localization
2.42 1.98e-02 GO:0006402 mRNA catabolic process
2.35 1.40e-03 GO:0006399 tRNA metabolic process
2.23 1.18e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.17 7.02e-05 GO:0034470 ncRNA processing
2.16 6.68e-10 GO:0006281 DNA repair
2.14 3.30e-07 GO:0034660 ncRNA metabolic process
2.12 4.95e-04 GO:0051169 nuclear transport
2.10 8.84e-04 GO:0006913 nucleocytoplasmic transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
4.96 1.79e-02 GO:0032300 mismatch repair complex
2.90 2.30e-02 GO:0008287 protein serine/threonine phosphatase complex
2.89 1.61e-03 GO:0034708 methyltransferase complex
2.89 1.61e-03 GO:0035097 histone methyltransferase complex
2.78 4.67e-04 GO:0000922 spindle pole
2.54 1.27e-03 GO:0031461 cullin-RING ubiquitin ligase complex
2.32 1.89e-04 GO:0044455 mitochondrial membrane part
2.18 1.07e-05 GO:0005819 spindle
2.10 1.65e-04 GO:0044454 nuclear chromosome part
2.09 2.44e-03 GO:0000151 ubiquitin ligase complex
2.01 2.89e-02 GO:0016607 nuclear speck
2.00 4.71e-14 GO:0005694 chromosome
1.99 6.73e-05 GO:0005813 centrosome
1.98 1.45e-04 GO:0000228 nuclear chromosome
1.96 1.03e-10 GO:0044427 chromosomal part
1.92 2.05e-04 GO:0000785 chromatin
1.91 4.31e-02 GO:0000793 condensed chromosome
1.90 2.24e-10 GO:0030529 ribonucleoprotein complex
1.88 3.08e-06 GO:0005815 microtubule organizing center
1.80 1.13e-23 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
4.78 1.21e-02 GO:0030983 mismatched DNA binding
2.34 4.38e-02 GO:0042393 histone binding
2.34 4.38e-02 GO:0047485 protein N-terminus binding
2.04 1.27e-05 GO:0019787 small conjugating protein ligase activity
2.03 4.09e-03 GO:0004518 nuclease activity
2.02 2.60e-06 GO:0016881 acid-amino acid ligase activity
1.99 7.68e-07 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.99 1.17e-04 GO:0004842 ubiquitin-protein ligase activity
1.99 8.15e-04 GO:0003682 chromatin binding
1.88 6.82e-17 GO:0003723 RNA binding
1.87 4.31e-02 GO:0004721 phosphoprotein phosphatase activity
1.86 3.72e-08 GO:0016874 ligase activity
1.62 1.55e-02 GO:0016887 ATPase activity
1.44 3.66e-03 GO:0017111 nucleoside-triphosphatase activity
1.43 3.38e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.43 4.22e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.43 4.29e-03 GO:0016462 pyrophosphatase activity
1.41 1.05e-18 GO:0003676 nucleic acid binding
1.36 1.31e-08 GO:0000166 nucleotide binding
1.34 3.00e-04 GO:0005524 ATP binding