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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: NRF1.p2

Z-value: 5.574

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_64301807	4.324	NM_001178031	SF1	splicing factor 1
chr19_-_51097694	4.069	NM_001012643	MYPOP	Myb-related transcription factor, partner of profilin
chr1_+_32251988	3.822	NM_006559	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1
chr2_-_33677798	3.745	NM_015475	FAM98A	family with sequence similarity 98, member A
chr4_-_56107725	3.100	NM_004898	CLOCK	clock homolog (mouse)
chr6_-_163754903	2.998		LOC100526820	hypothetical LOC100526820
chr6_-_33787413	2.928		C6orf125	chromosome 6 open reading frame 125
chr14_+_22633728	2.909		C14orf119	chromosome 14 open reading frame 119
chr21_+_33619147	2.851		IFNAR1	interferon (alpha, beta and omega) receptor 1
chr17_-_44794325	2.781	NM_001145365 NM_014897	ZNF652	zinc finger protein 652
chr6_-_33787479	2.542	NM_032340	C6orf125	chromosome 6 open reading frame 125
chr17_-_35510074	2.510		NR1D1	nuclear receptor subfamily 1, group D, member 1
chr21_+_33066281	2.509		C21orf49	chromosome 21 open reading frame 49
chr11_+_64785888	2.371	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr12_-_123023052	2.348	NM_025140	CCDC92	coiled-coil domain containing 92
chr3_+_43303005	2.332	NM_001100594 NM_017719	SNRK	SNF related kinase
chr1_-_19409328	2.331	NM_020765	UBR4	ubiquitin protein ligase E3 component n-recognin 4
chr1_-_16174859	2.330	NM_003443	ZBTB17	zinc finger and BTB domain containing 17
chr3_+_49424642	2.329	NM_022171	TCTA	T-cell leukemia translocation altered gene
chr2_-_197499584	2.298	NM_024989	PGAP1	post-GPI attachment to proteins 1
chr2_+_71149193	2.281		NAGK	N-acetylglucosamine kinase
chr18_-_12874140	2.227	NM_002828 NM_080422 NM_080423	PTPN2	protein tyrosine phosphatase, non-receptor type 2
chr1_-_201124848	2.221	NM_002871	RABIF	RAB interacting factor
chr16_+_48657381	2.214	NM_182922	HEATR3	HEAT repeat containing 3
chr17_-_24302597	2.204	NM_001033561 NM_020889	PHF12	PHD finger protein 12
chr16_+_4415805	2.198	NM_001135110 NM_005147	DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3
chr6_+_33044353	2.185
chr9_+_132990834	2.158		NUP214	nucleoporin 214kDa
chr3_+_10132314	2.116	NM_018462	C3orf10	chromosome 3 open reading frame 10
chr22_+_22737753	2.097	NM_012295	CABIN1	calcineurin binding protein 1
chr21_-_33065849	2.093	NM_013329 NM_016631	GCFC1	GC-rich sequence DNA-binding factor 1
chr17_-_35510431	2.074	NM_021724	NR1D1	nuclear receptor subfamily 1, group D, member 1
chr12_+_105275989	2.042	NM_001160708	POLR3B	polymerase (RNA) III (DNA directed) polypeptide B
chr1_+_3763704	2.038	NM_004402	DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr6_+_33044378	2.020	NM_005104	BRD2	bromodomain containing 2
chr22_-_19543012	2.013		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr9_+_132990760	2.010	NM_005085	NUP214	nucleoporin 214kDa
chr16_+_48657408	1.952		HEATR3	HEAT repeat containing 3
chr1_+_148603208	1.903		RPRD2	regulation of nuclear pre-mRNA domain containing 2
chr2_+_28828112	1.899	NM_206876 NM_002709	PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme
chr19_-_4351470	1.875	NM_003025	SH3GL1	SH3-domain GRB2-like 1
chr22_-_21193037	1.873		ZNF280B	zinc finger protein 280B
chr6_-_150011450	1.853		KATNA1	katanin p60 (ATPase containing) subunit A 1
chr1_+_91739241	1.849	NM_001134420	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr17_-_45110339	1.836	NM_001007226 NM_001007227 NM_001007228 NM_001007229 NM_001007230 NM_003563	SPOP	speckle-type POZ protein
chr12_-_107775400	1.818		SSH1	slingshot homolog 1 (Drosophila)
chr6_-_43651578	1.797		XPO5	exportin 5
chr4_+_6768682	1.790	NM_018366	CNO	cappuccino homolog (mouse)
chr3_+_15222747	1.789		CAPN7	calpain 7
chr21_-_46703020	1.787
chr22_-_19543069	1.784	NM_058004	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr4_+_6768800	1.773		CNO	cappuccino homolog (mouse)
chr20_-_48163071	1.772	NM_001032288	UBE2V1	ubiquitin-conjugating enzyme E2 variant 1
chr20_-_30003386	1.769		PDRG1	p53 and DNA-damage regulated 1
chr17_-_24302450	1.757		PHF12	PHD finger protein 12
chr3_+_151803755	1.755	NM_016275	SELT	selenoprotein T
chr10_+_133995587	1.737	NM_001143758 NM_001143759 NM_030626	LRRC27	leucine rich repeat containing 27
chr5_-_132101042	1.721	NM_007054	KIF3A	kinesin family member 3A
chr6_-_36623038	1.716		STK38	serine/threonine kinase 38
chr5_-_271235	1.714	NM_145265	CCDC127	coiled-coil domain containing 127
chr1_+_46041870	1.712	NM_015112	MAST2	microtubule associated serine/threonine kinase 2
chr2_-_37164962	1.700	NM_019024	HEATR5B	HEAT repeat containing 5B
chr22_-_21814208	1.685	NM_014433	RTDR1	rhabdoid tumor deletion region gene 1
chr1_+_91738953	1.671	NM_001134419 NM_003503	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr20_-_34807882	1.659	NM_022477 NM_032013	NDRG3	NDRG family member 3
chr19_+_61607505	1.651	NM_152478 NM_001159861	ZNF583	zinc finger protein 583
chr3_-_184180985	1.648	NM_020640	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)
chr6_-_39190728	1.639	NM_018322	C6orf64	chromosome 6 open reading frame 64
chr17_-_23244499	1.638	NM_001076680	C17orf108	chromosome 17 open reading frame 108
chr2_-_37164919	1.638		HEATR5B	HEAT repeat containing 5B
chr22_-_19686351	1.624	NM_001008695 NM_030573	THAP7	THAP domain containing 7
chr8_-_42870779	1.615	NM_001160223 NM_001160224 NM_001160225 NM_030954	RNF170	ring finger protein 170
chr1_+_35507197	1.608		ZMYM4	zinc finger, MYM-type 4
chr17_+_72648580	1.579	NM_001039573 NM_001143998 NM_001143999 NM_003003	SEC14L1	SEC14-like 1 (S. cerevisiae)
chr5_-_176365971	1.566	NM_016290	UIMC1	ubiquitin interaction motif containing 1
chr19_-_44032202	1.564		HNRNPL	heterogeneous nuclear ribonucleoprotein L
chr21_+_37367432	1.563	NM_001001894	TTC3	tetratricopeptide repeat domain 3
chr1_-_16551514	1.546	NM_018994	FBXO42	F-box protein 42
chr10_+_86078136	1.546	NM_018999	FAM190B	family with sequence similarity 190, member B
chr19_+_1358664	1.544		DAZAP1	DAZ associated protein 1
chr5_+_134209628	1.543		C5orf24	chromosome 5 open reading frame 24
chr10_+_133995629	1.543	NM_001143757	LRRC27	leucine rich repeat containing 27
chr19_-_7874426	1.536
chr22_-_19543099	1.518		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr9_+_138959518	1.518	NM_000606	C8G	complement component 8, gamma polypeptide
chr7_+_99865340	1.516		MEPCE	methylphosphate capping enzyme
chr6_-_36623223	1.509	NM_007271	STK38	serine/threonine kinase 38
chr7_+_12217343	1.509	NM_001134232 NM_018374	TMEM106B	transmembrane protein 106B
chr19_-_48815853	1.490	NM_182498	ZNF428	zinc finger protein 428
chr10_+_27833167	1.489	NM_021252	RAB18	RAB18, member RAS oncogene family
chr5_+_134209444	1.485	NM_001135586	C5orf24	chromosome 5 open reading frame 24
chr4_+_26471410	1.483	NM_001169117 NM_001169118 NM_020860	STIM2	stromal interaction molecule 2
chr3_+_44354594	1.482	NM_001029840	C3orf23	chromosome 3 open reading frame 23
chr5_+_112071087	1.467	NM_001127511	APC	adenomatous polyposis coli
chr5_+_134209268	1.465	NM_152409	C5orf24	chromosome 5 open reading frame 24
chrX_-_30817329	1.464	NM_152787	TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_-_247119516	1.458	NM_001136036	ZNF692	zinc finger protein 692
chr3_-_14963943	1.458
chr20_+_36534871	1.458	NM_020336	RALGAPB	Ral GTPase activating protein, beta subunit (non-catalytic)
chr22_+_19078397	1.458	NM_003426	ZNF74	zinc finger protein 74
chr6_+_13682628	1.447	NM_001193267 NM_031244 NM_012241	SIRT5	sirtuin 5
chr15_+_57067141	1.440	NM_017610	RNF111	ring finger protein 111
chr1_-_3763620	1.430	NM_014704	KIAA0562	KIAA0562
chrX_+_151860870	1.429	NM_001178115	ZNF185	zinc finger protein 185 (LIM domain)
chr11_+_63205444	1.427	NM_006054 NM_201428 NM_201429 NM_201430	RTN3	reticulon 3
chr6_+_2710602	1.426	NM_020135 NM_130395	WRNIP1	Werner helicase interacting protein 1
chr2_-_112729072	1.424	NM_032494	ZC3H8	zinc finger CCCH-type containing 8
chr12_+_68418829	1.424	NM_022456 NM_175624	RAB3IP	RAB3A interacting protein (rabin3)
chr12_-_26982144	1.420		C12orf11	chromosome 12 open reading frame 11
chr16_+_27122307	1.418	NM_024773	JMJD5	jumonji domain containing 5
chr12_+_47810915	1.414
chr1_-_3763480	1.414		KIAA0562	KIAA0562
chr16_+_29892714	1.401	NM_004783 NM_016151	TAOK2	TAO kinase 2
chr10_-_16899395	1.400		RSU1	Ras suppressor protein 1
chr17_+_4683280	1.397	NM_001024937 NM_015716 NM_153827 NM_170663	MINK1	misshapen-like kinase 1
chr16_+_30876959	1.390
chr3_+_44355007	1.388		C3orf23	chromosome 3 open reading frame 23
chr7_-_124357272	1.379	NM_001042594 NM_015450	POT1	protection of telomeres 1 homolog (S. pombe)
chr19_+_47480445	1.375	NM_015125	CIC	capicua homolog (Drosophila)
chr6_+_44463418	1.375		CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr2_+_118562499	1.366	NM_016133	INSIG2	insulin induced gene 2
chr9_+_107496638	1.365	NM_018112	TMEM38B	transmembrane protein 38B
chr7_+_116289833	1.363		CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2
chr12_+_56202874	1.363	NM_052897	MBD6	methyl-CpG binding domain protein 6
chr2_+_98427737	1.363	NM_001134224 NM_001134225 NM_001566 NM_004027	INPP4A	inositol polyphosphate-4-phosphatase, type I, 107kDa
chr12_+_81604752	1.358		TMTC2	transmembrane and tetratricopeptide repeat containing 2
chr11_+_18374388	1.358	NM_001165414	LDHA	lactate dehydrogenase A
chr1_+_27972269	1.338	NM_177424	STX12	syntaxin 12
chr12_-_116112495	1.337	NM_015002 NM_033624	FBXO21	F-box protein 21
chr7_-_104816487	1.337
chr4_-_121207338	1.329	NM_002358	MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)
chr16_+_86542449	1.322	NM_001173539 NM_001173540 NM_001173541 NM_017869 NM_079837	BANP	BTG3 associated nuclear protein
chr22_+_19686434	1.320		FLJ39582	hypothetical LOC439931
chr3_-_17759100	1.319	NM_001134380	TBC1D5	TBC1 domain family, member 5
chr2_-_106177166	1.318		UXS1	UDP-glucuronate decarboxylase 1
chr1_+_196138304	1.317	NM_001024594	C1orf53	chromosome 1 open reading frame 53
chr6_+_44463265	1.315	NM_001253	CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr16_-_30288988	1.313	NM_015527	TBC1D10B	TBC1 domain family, member 10B
chr14_+_101500650	1.308		DYNC1H1	dynein, cytoplasmic 1, heavy chain 1
chr7_+_158341961	1.306	NM_018051	WDR60	WD repeat domain 60
chr19_+_47416338	1.302		ZNF526	zinc finger protein 526
chr3_+_44354927	1.299	NM_001029839 NM_173826	C3orf23	chromosome 3 open reading frame 23
chr6_-_150011542	1.294		KATNA1	katanin p60 (ATPase containing) subunit A 1
chr10_+_59698891	1.292	NM_018464	CISD1	CDGSH iron sulfur domain 1
chr22_+_22737814	1.290		CABIN1	calcineurin binding protein 1
chr9_-_37894098	1.288		MCART1	mitochondrial carrier triple repeat 1
chr21_-_37366684	1.278	NM_153681	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr2_+_79593679	1.277		CTNNA2	catenin (cadherin-associated protein), alpha 2
chr10_-_71663076	1.276	NM_021129	PPA1	pyrophosphatase (inorganic) 1
chr22_+_22737870	1.276		CABIN1	calcineurin binding protein 1
chr6_+_2710560	1.275		WRNIP1	Werner helicase interacting protein 1
chr2_+_37165097	1.268	NM_174931	CCDC75	coiled-coil domain containing 75
chr17_-_7458574	1.266		FXR2	fragile X mental retardation, autosomal homolog 2
chr14_+_63924779	1.265		MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr19_+_47416271	1.260	NM_133444	ZNF526	zinc finger protein 526
chr22_-_19685998	1.256		THAP7	THAP domain containing 7
chr5_+_112340326	1.255	NM_152624	DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)
chr17_+_35531742	1.255		MSL1	male-specific lethal 1 homolog (Drosophila)
chr2_+_42249896	1.250	NM_001145076 NM_019063	EML4	echinoderm microtubule associated protein like 4
chr2_+_196230096	1.246	NM_020342	SLC39A10	solute carrier family 39 (zinc transporter), member 10
chr18_-_5286013	1.245	NM_001143823 NM_003409	ZFP161	zinc finger protein 161 homolog (mouse)
chr11_-_75769514	1.243	NM_004705	PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr17_-_40750109	1.241	NM_003954	MAP3K14	mitogen-activated protein kinase kinase kinase 14
chr1_-_52604405	1.241	NM_032449	CC2D1B	coiled-coil and C2 domain containing 1B
chr12_-_123023312	1.239		CCDC92	coiled-coil domain containing 92
chr14_-_22127902	1.238		DAD1	defender against cell death 1
chr22_+_19543350	1.238		SNAP29	synaptosomal-associated protein, 29kDa
chr11_-_59193064	1.237	NM_152716	PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr6_-_39190925	1.229		C6orf64	chromosome 6 open reading frame 64
chr6_-_35996794	1.227		SRPK1	SRSF protein kinase 1
chrX_-_152517629	1.226		FAM58A	family with sequence similarity 58, member A
chr14_-_23981493	1.224	NM_020195	SDR39U1	short chain dehydrogenase/reductase family 39U, member 1
chr22_+_19543248	1.220	NM_004782	SNAP29	synaptosomal-associated protein, 29kDa
chr7_-_44588365	1.219		TMED4	transmembrane emp24 protein transport domain containing 4
chr19_+_54280211	1.219	NM_003089	SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr3_+_44355217	1.214		C3orf23	chromosome 3 open reading frame 23
chr16_+_28741873	1.212		ATXN2L	ataxin 2-like
chr5_+_170747312	1.210	NM_001037738 NM_002520 NM_199185	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr6_-_43651745	1.210	NM_020750	XPO5	exportin 5
chrX_-_152517815	1.209	NM_001130997 NM_152274	FAM58A	family with sequence similarity 58, member A
chr5_+_170747543	1.207		NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr11_-_65382226	1.205
chr6_-_150011551	1.204		KATNA1	katanin p60 (ATPase containing) subunit A 1
chr3_-_47492320	1.201		SCAP	SREBF chaperone
chr3_-_198839026	1.199		LOC220729	succinate dehydrogenase complex, subunit A, flavoprotein pseudogene
chr6_-_43651727	1.192		XPO5	exportin 5
chr2_+_100545827	1.189	NM_024065	PDCL3	phosducin-like 3
chr1_+_229540304	1.183	NM_001010984 NM_032018	C1orf124	chromosome 1 open reading frame 124
chr1_-_39111422	1.182	NM_012333	MYCBP	c-myc binding protein
chr21_+_33619067	1.181	NM_000629	IFNAR1	interferon (alpha, beta and omega) receptor 1
chr11_-_65382228	1.180		CFL1	cofilin 1 (non-muscle)
chr6_-_153346283	1.179	NM_001142522	FBXO5	F-box protein 5
chr1_-_247119908	1.178	NM_001193328 NM_017865	ZNF692	zinc finger protein 692
chr1_+_20081510	1.175
chr7_+_116289827	1.167		CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2
chr9_+_114182216	1.167		HSDL2	hydroxysteroid dehydrogenase like 2
chr2_+_71148915	1.164	NM_017567	NAGK	N-acetylglucosamine kinase
chr21_-_34209897	1.162	NM_001697	ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr14_-_22634134	1.161		ACIN1	apoptotic chromatin condensation inducer 1
chrX_+_47305459	1.158	NM_001654	ARAF	v-raf murine sarcoma 3611 viral oncogene homolog

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.54	8.26e-46	GO:0044260	cellular macromolecule metabolic process
1.44	2.99e-36	GO:0043170	macromolecule metabolic process
1.37	5.13e-36	GO:0044237	cellular metabolic process
1.32	4.22e-28	GO:0044238	primary metabolic process
1.29	2.87e-27	GO:0008152	metabolic process
1.65	2.35e-26	GO:0090304	nucleic acid metabolic process
1.56	1.24e-25	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.58	1.91e-24	GO:0044267	cellular protein metabolic process
1.47	2.25e-21	GO:0034641	cellular nitrogen compound metabolic process
1.45	5.35e-21	GO:0006807	nitrogen compound metabolic process
1.58	7.58e-17	GO:0010467	gene expression
1.43	3.29e-16	GO:0019538	protein metabolic process
1.59	7.53e-16	GO:0016070	RNA metabolic process
1.98	2.43e-14	GO:0006396	RNA processing
1.94	1.14e-12	GO:0051276	chromosome organization
2.03	3.08e-12	GO:0006974	response to DNA damage stimulus
1.48	5.73e-12	GO:0043412	macromolecule modification
1.94	6.75e-12	GO:0006259	DNA metabolic process
1.53	7.99e-12	GO:0006996	organelle organization
1.76	2.05e-11	GO:0033554	cellular response to stress
1.48	4.05e-11	GO:0006464	protein modification process
2.16	6.68e-10	GO:0006281	DNA repair
1.76	4.71e-09	GO:0022403	cell cycle phase
1.46	1.17e-08	GO:0034645	cellular macromolecule biosynthetic process
1.11	1.59e-08	GO:0009987	cellular process
1.86	1.78e-08	GO:0044265	cellular macromolecule catabolic process
1.45	1.82e-08	GO:0009059	macromolecule biosynthetic process
1.84	2.26e-08	GO:0016071	mRNA metabolic process
1.58	4.98e-08	GO:0007049	cell cycle
1.91	9.42e-08	GO:0000279	M phase
1.66	1.22e-07	GO:0046907	intracellular transport
1.32	1.87e-07	GO:0071841	cellular component organization or biogenesis at cellular level
2.06	3.26e-07	GO:0006412	translation
2.14	3.30e-07	GO:0034660	ncRNA metabolic process
1.63	3.46e-07	GO:0022402	cell cycle process
1.73	3.57e-07	GO:0009057	macromolecule catabolic process
1.51	5.74e-07	GO:0044248	cellular catabolic process
1.82	1.01e-06	GO:0006325	chromatin organization
2.08	1.28e-06	GO:0032446	protein modification by small protein conjugation
1.73	1.48e-06	GO:0000278	mitotic cell cycle
1.58	2.19e-06	GO:0045184	establishment of protein localization
1.96	2.55e-06	GO:0070647	protein modification by small protein conjugation or removal
1.31	2.64e-06	GO:0071842	cellular component organization at cellular level
1.58	3.19e-06	GO:0015031	protein transport
2.08	4.92e-06	GO:0016567	protein ubiquitination
2.48	8.23e-06	GO:0006310	DNA recombination
1.88	8.94e-06	GO:0016568	chromatin modification
1.49	1.18e-05	GO:0008104	protein localization
1.24	1.93e-05	GO:0071840	cellular component organization or biogenesis
3.08	2.14e-05	GO:0006302	double-strand break repair
1.95	2.47e-05	GO:0000087	M phase of mitotic cell cycle
1.30	4.01e-05	GO:0044249	cellular biosynthetic process
1.81	5.58e-05	GO:0006397	mRNA processing
1.42	5.78e-05	GO:0033036	macromolecule localization
2.17	7.02e-05	GO:0034470	ncRNA processing
2.81	8.76e-05	GO:0051168	nuclear export
2.55	9.11e-05	GO:0051028	mRNA transport
3.04	9.68e-05	GO:0006405	RNA export from nucleus
2.44	1.04e-04	GO:0006403	RNA localization
2.46	1.20e-04	GO:0050657	nucleic acid transport
2.46	1.20e-04	GO:0050658	RNA transport
2.46	1.20e-04	GO:0051236	establishment of RNA localization
1.89	1.32e-04	GO:0008380	RNA splicing
1.28	1.41e-04	GO:0009058	biosynthetic process
1.23	1.97e-04	GO:0016043	cellular component organization
1.89	1.98e-04	GO:0000280	nuclear division
1.89	1.98e-04	GO:0007067	mitosis
1.38	2.57e-04	GO:0009056	catabolic process
1.40	2.61e-04	GO:0051641	cellular localization
1.86	3.44e-04	GO:0048285	organelle fission
1.81	4.53e-04	GO:0044257	cellular protein catabolic process
2.12	4.95e-04	GO:0051169	nuclear transport
3.03	6.33e-04	GO:0006406	mRNA export from nucleus
1.80	8.33e-04	GO:0043632	modification-dependent macromolecule catabolic process
2.10	8.84e-04	GO:0006913	nucleocytoplasmic transport
1.79	8.95e-04	GO:0051603	proteolysis involved in cellular protein catabolic process
1.75	9.44e-04	GO:0030163	protein catabolic process
2.23	1.18e-03	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.41	1.24e-03	GO:0051649	establishment of localization in cell
1.80	1.25e-03	GO:0006511	ubiquitin-dependent protein catabolic process
1.79	1.34e-03	GO:0019941	modification-dependent protein catabolic process
2.35	1.40e-03	GO:0006399	tRNA metabolic process
1.73	1.92e-03	GO:0044419	interspecies interaction between organisms
1.95	2.27e-03	GO:0009203	ribonucleoside triphosphate catabolic process
1.95	2.27e-03	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.94	2.68e-03	GO:0009146	purine nucleoside triphosphate catabolic process
2.06	2.77e-03	GO:0043687	post-translational protein modification
1.91	4.34e-03	GO:0009143	nucleoside triphosphate catabolic process
1.91	4.34e-03	GO:0009154	purine ribonucleotide catabolic process
1.71	5.73e-03	GO:0018193	peptidyl-amino acid modification
1.89	5.93e-03	GO:0009261	ribonucleotide catabolic process
1.94	7.07e-03	GO:0000375	RNA splicing, via transesterification reactions
2.63	1.29e-02	GO:0006200	ATP catabolic process
2.51	1.35e-02	GO:0000956	nuclear-transcribed mRNA catabolic process
1.91	1.71e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.91	1.71e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
2.42	1.98e-02	GO:0006402	mRNA catabolic process
1.75	2.39e-02	GO:0010608	posttranscriptional regulation of gene expression
1.79	2.60e-02	GO:0072523	purine-containing compound catabolic process
1.70	4.33e-02	GO:0009199	ribonucleoside triphosphate metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.23	2.24e-61	GO:0005622	intracellular
1.24	2.53e-59	GO:0044424	intracellular part
1.33	1.22e-57	GO:0043231	intracellular membrane-bounded organelle
1.33	1.40e-57	GO:0043227	membrane-bounded organelle
1.28	3.47e-54	GO:0043229	intracellular organelle
1.28	1.58e-53	GO:0043226	organelle
1.45	2.35e-46	GO:0005634	nucleus
1.74	9.10e-36	GO:0044428	nuclear part
1.38	1.03e-33	GO:0044446	intracellular organelle part
1.37	6.00e-32	GO:0044422	organelle part
1.74	1.67e-29	GO:0031981	nuclear lumen
1.65	1.44e-28	GO:0070013	intracellular organelle lumen
1.62	1.10e-27	GO:0031974	membrane-enclosed lumen
1.62	4.91e-27	GO:0043233	organelle lumen
1.80	1.13e-23	GO:0005654	nucleoplasm
1.21	2.33e-21	GO:0005737	cytoplasm
1.40	2.98e-19	GO:0032991	macromolecular complex
2.00	4.71e-14	GO:0005694	chromosome
1.23	8.06e-14	GO:0044444	cytoplasmic part
1.43	3.57e-11	GO:0005829	cytosol
1.96	1.03e-10	GO:0044427	chromosomal part
1.33	1.89e-10	GO:0043234	protein complex
1.90	2.24e-10	GO:0030529	ribonucleoprotein complex
1.34	3.75e-10	GO:0043228	non-membrane-bounded organelle
1.34	3.75e-10	GO:0043232	intracellular non-membrane-bounded organelle
1.72	1.13e-09	GO:0044451	nucleoplasm part
1.05	4.10e-08	GO:0044464	cell part
1.05	4.33e-08	GO:0005623	cell
1.45	2.05e-07	GO:0005739	mitochondrion
1.88	3.08e-06	GO:0005815	microtubule organizing center
1.71	4.28e-06	GO:0005730	nucleolus
2.18	1.07e-05	GO:0005819	spindle
1.99	6.73e-05	GO:0005813	centrosome
1.53	1.35e-04	GO:0015630	microtubule cytoskeleton
1.98	1.45e-04	GO:0000228	nuclear chromosome
2.10	1.65e-04	GO:0044454	nuclear chromosome part
2.32	1.89e-04	GO:0044455	mitochondrial membrane part
1.92	2.05e-04	GO:0000785	chromatin
2.78	4.67e-04	GO:0000922	spindle pole
1.50	6.69e-04	GO:0044429	mitochondrial part
1.48	7.53e-04	GO:0031967	organelle envelope
2.54	1.27e-03	GO:0031461	cullin-RING ubiquitin ligase complex
2.89	1.61e-03	GO:0034708	methyltransferase complex
2.89	1.61e-03	GO:0035097	histone methyltransferase complex
1.45	1.97e-03	GO:0031975	envelope
2.09	2.44e-03	GO:0000151	ubiquitin ligase complex
1.61	1.32e-02	GO:0019866	organelle inner membrane
1.63	1.63e-02	GO:0005743	mitochondrial inner membrane
4.96	1.79e-02	GO:0032300	mismatch repair complex
2.90	2.30e-02	GO:0008287	protein serine/threonine phosphatase complex
1.22	2.32e-02	GO:0031090	organelle membrane
2.01	2.89e-02	GO:0016607	nuclear speck
1.91	4.31e-02	GO:0000793	condensed chromosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.24	3.29e-21	GO:0005515	protein binding
1.41	1.05e-18	GO:0003676	nucleic acid binding
1.88	6.82e-17	GO:0003723	RNA binding
1.10	1.75e-10	GO:0005488	binding
1.23	1.77e-10	GO:0003824	catalytic activity
1.36	1.31e-08	GO:0000166	nucleotide binding
1.86	3.72e-08	GO:0016874	ligase activity
1.99	7.68e-07	GO:0016879	ligase activity, forming carbon-nitrogen bonds
2.02	2.60e-06	GO:0016881	acid-amino acid ligase activity
2.04	1.27e-05	GO:0019787	small conjugating protein ligase activity
1.29	2.76e-05	GO:0003677	DNA binding
1.31	8.35e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.99	1.17e-04	GO:0004842	ubiquitin-protein ligase activity
1.30	1.69e-04	GO:0017076	purine nucleotide binding
1.30	2.01e-04	GO:0032553	ribonucleotide binding
1.30	2.01e-04	GO:0032555	purine ribonucleotide binding
1.34	3.00e-04	GO:0005524	ATP binding
1.32	5.54e-04	GO:0030554	adenyl nucleotide binding
1.32	7.41e-04	GO:0032559	adenyl ribonucleotide binding
1.99	8.15e-04	GO:0003682	chromatin binding
1.43	3.38e-03	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.44	3.66e-03	GO:0017111	nucleoside-triphosphatase activity
2.03	4.09e-03	GO:0004518	nuclease activity
1.43	4.22e-03	GO:0016817	hydrolase activity, acting on acid anhydrides
1.43	4.29e-03	GO:0016462	pyrophosphatase activity
4.78	1.21e-02	GO:0030983	mismatched DNA binding
1.62	1.55e-02	GO:0016887	ATPase activity
1.25	2.57e-02	GO:0016740	transferase activity
1.87	4.31e-02	GO:0004721	phosphoprotein phosphatase activity
2.34	4.38e-02	GO:0042393	histone binding
2.34	4.38e-02	GO:0047485	protein N-terminus binding