Motif ID: PATZ1.p2

Z-value: 1.699


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_30072217-0.401.4e-01Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_150305933 3.151 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr11_+_65049102 2.310 NM_001048218
NM_020680
SCYL1

SCY1-like 1 (S. cerevisiae)

chr9_+_132961723 2.155 AIF1L
allograft inflammatory factor 1-like
chr22_+_18081968 2.071 NM_002688
SEPT5
septin 5
chr22_-_21231421 2.005 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr11_+_65049152 1.913 SCYL1
SCY1-like 1 (S. cerevisiae)
chr19_-_53950458 1.910 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr5_+_172193826 1.862 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr6_+_33495824 1.848 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr7_-_150306169 1.844 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr9_+_132961683 1.642 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr19_+_45728207 1.635 NM_025213
SPTBN4
spectrin, beta, non-erythrocytic 4
chr21_+_43267703 1.598 NM_004571
PKNOX1
PBX/knotted 1 homeobox 1
chr21_+_43267760 1.559 PKNOX1
PBX/knotted 1 homeobox 1
chr19_+_53951155 1.500 NM_019113
FGF21
fibroblast growth factor 21
chr22_-_17489912 1.487 NM_001173533
NM_001173534
NM_001184781
NM_005137
DGCR2



DiGeorge syndrome critical region gene 2



chr16_+_2503676 1.474 NM_001198569
NM_001694
ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr22_-_17489718 1.441 DGCR2
DiGeorge syndrome critical region gene 2
chr1_+_111963920 1.426 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr20_+_30813851 1.398 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr19_+_45728270 1.360 SPTBN4
spectrin, beta, non-erythrocytic 4
chr19_+_60487578 1.342 BRSK1
BR serine/threonine kinase 1
chr1_+_204924931 1.341 MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr17_+_52688842 1.300 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr19_-_55524445 1.268 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr7_-_100077072 1.261 NM_003227
TFR2
transferrin receptor 2
chr7_-_127833231 1.236 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr16_+_29892714 1.220 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr22_-_49042065 1.203 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr19_-_15421761 1.202 NM_021241
WIZ
widely interspaced zinc finger motifs
chr1_-_117011824 1.182 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr22_+_20101661 1.176 NM_015094
HIC2
hypermethylated in cancer 2
chr9_+_94860828 1.160 SUSD3
sushi domain containing 3
chr7_-_150283794 1.159 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_-_118740069 1.152 NM_171997
USP2
ubiquitin specific peptidase 2
chr17_-_37586716 1.145 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr9_-_125732005 1.112 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chr19_-_56585603 1.110 NM_001193623
LOC147646
hypothetical protein LOC147646
chr2_+_170298487 1.108


chr17_+_72789086 1.098 NM_001113491
SEPT9
septin 9
chr7_-_102044374 1.095 RASA4
RAS p21 protein activator 4
chr20_+_60906605 1.077 NM_007346
OGFR
opioid growth factor receptor
chr22_-_17545872 1.069 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_-_54636425 1.064 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr2_+_27518736 1.058 NM_001168364
NM_173853
KRTCAP3

keratinocyte associated protein 3

chr9_+_102275310 1.057 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_+_47040863 1.052 NM_001040283
DMRTC2
DMRT-like family C2
chr9_+_94860769 1.051 NM_145006
SUSD3
sushi domain containing 3
chr1_+_945331 1.050 NM_198576
AGRN
agrin
chr9_-_122679387 1.047 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr7_+_128219307 1.044 NM_022742
CCDC136
coiled-coil domain containing 136
chr1_-_1283770 1.038 NM_032348
MXRA8
matrix-remodelling associated 8
chr8_-_145671947 1.031 FOXH1
forkhead box H1
chr10_-_75304225 1.029 NM_001222
NM_172169
NM_172171
NM_172173
NM_172170
CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr22_+_18085990 1.027 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr19_-_55834895 1.025 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr7_-_129379947 1.021 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr16_+_2503915 1.021 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_-_38243747 1.018 NM_004468
FHL3
four and a half LIM domains 3
chr8_+_144706699 1.013 NM_001166237
GSDMD
gasdermin D
chr19_-_51983434 1.009 NM_005628
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr11_-_118739838 1.006 USP2
ubiquitin specific peptidase 2
chr1_-_32574185 1.000 NM_023009
MARCKSL1
MARCKS-like 1
chr14_-_21064182 0.995 SALL2
sal-like 2 (Drosophila)
chr2_+_170298700 0.993 KLHL23
kelch-like 23 (Drosophila)
chr8_-_144887876 0.989 NM_198488
FAM83H
family with sequence similarity 83, member H
chr7_-_102044419 0.986 NM_001079877
NM_006989
RASA4

RAS p21 protein activator 4

chr2_+_220087135 0.986 NM_018674
NM_182847
ACCN4

amiloride-sensitive cation channel 4, pituitary

chr19_+_12805747 0.975 MAST1
microtubule associated serine/threonine kinase 1
chr17_+_26446067 0.972 NM_000267
NM_001042492
NM_001128147
NF1


neurofibromin 1


chr12_+_109046522 0.968 NM_001143779
NM_014055
NM_031473
IFT81


intraflagellar transport 81 homolog (Chlamydomonas)


chr16_+_2461500 0.949 NM_006181
NTN3
netrin 3
chr5_-_1348103 0.948 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chrX_-_153632990 0.943 GAB3
GRB2-associated binding protein 3
chr18_+_3439972 0.935 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr22_-_18384251 0.933 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr22_+_18085891 0.931 SEPT5
septin 5
chr11_+_56984702 0.925 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr20_-_31737815 0.923 NM_005225
E2F1
E2F transcription factor 1
chr1_-_36721010 0.923 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr7_-_44152232 0.917 GCK
glucokinase (hexokinase 4)
chr19_+_10404110 0.916 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr1_+_945472 0.915 AGRN
agrin
chr19_-_2653662 0.914 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr15_-_100082134 0.913 NM_152334
TARSL2
threonyl-tRNA synthetase-like 2
chr15_-_19221463 0.910


chr1_-_21375891 0.905 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr11_-_64268841 0.897 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr6_-_42527760 0.895 NM_033502
TRERF1
transcriptional regulating factor 1
chr3_-_13436802 0.894 NM_024923
NUP210
nucleoporin 210kDa
chr19_+_4255590 0.893 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr4_+_154606900 0.892 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr1_-_21375939 0.890 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr5_-_176833197 0.887 DBN1
drebrin 1
chr6_-_33393471 0.887 NM_005453
ZBTB22
zinc finger and BTB domain containing 22
chr7_-_44152252 0.884 GCK
glucokinase (hexokinase 4)
chr10_+_49184658 0.879 MAPK8
mitogen-activated protein kinase 8
chr19_-_1966628 0.878 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr19_+_659766 0.877 NM_001040134
NM_002579
PALM

paralemmin

chr16_-_87280380 0.865 NM_178310
SNAI3
snail homolog 3 (Drosophila)
chr16_+_1979959 0.860 NM_004209
SYNGR3
synaptogyrin 3
chr7_-_106088565 0.854 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr12_+_54700955 0.852 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr1_+_26728846 0.852 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr1_-_223907283 0.850 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr20_+_44083667 0.846 NM_001134771
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr19_-_52667056 0.845 NM_015063
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr3_-_13436725 0.845 NUP210
nucleoporin 210kDa
chr16_+_2503978 0.843 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr16_+_2503994 0.843 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr11_-_72170533 0.839 STARD10
StAR-related lipid transfer (START) domain containing 10
chr4_+_48180033 0.837 NM_152679
SLC10A4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr9_-_134986108 0.836 NM_006266
RALGDS
ral guanine nucleotide dissociation stimulator
chr19_-_2653738 0.834 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr1_+_3679168 0.834 NM_001163724
LOC388588
hypothetical protein LOC388588
chr2_-_25328452 0.825 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr22_-_17546296 0.824 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr21_-_43369492 0.823 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr19_+_60505205 0.823 BRSK1
BR serine/threonine kinase 1
chr19_+_40223249 0.809 NM_002151
NM_182983
HPN

hepsin

chr1_-_21868380 0.804 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr19_+_50041424 0.803 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr22_-_16637238 0.802 NM_001196
NM_197967
BID

BH3 interacting domain death agonist

chr22_+_38183480 0.802 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr19_+_13066956 0.801 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chrX_+_9392980 0.799 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr17_-_78199384 0.799 NM_019613
WDR45L
WDR45-like
chr1_-_152797820 0.798 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr1_-_154318412 0.797 NM_001093725
MEX3A
mex-3 homolog A (C. elegans)
chr19_-_14177980 0.794 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr19_+_11327173 0.790 LPPR2
lipid phosphate phosphatase-related protein type 2
chr16_+_80036275 0.788 NM_198390
CMIP
c-Maf-inducing protein
chr3_+_184898234 0.787 NM_018023
YEATS2
YEATS domain containing 2
chr1_+_41022066 0.786 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr1_-_199259133 0.786 KIF21B
kinesin family member 21B
chr6_-_31977747 0.784 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr9_+_130491340 0.782 SET
SET nuclear oncogene
chr20_-_55533544 0.781 NM_080618
CTCFL
CCCTC-binding factor (zinc finger protein)-like
chr1_-_159787004 0.781 NM_001127593
NM_001127595
NM_001127596
FCGR3A


Fc fragment of IgG, low affinity IIIa, receptor (CD16a)


chr16_+_87741416 0.776


chr20_-_62181588 0.775 NM_001039467
RGS19
regulator of G-protein signaling 19
chr7_+_150414704 0.774 NM_001042535
NM_031946
AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

chr6_+_4081241 0.769 LOC100507506
hypothetical LOC100507506
chr19_-_2979901 0.768 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr7_+_149042960 0.765 NM_032534
KRBA1
KRAB-A domain containing 1
chr6_+_43151922 0.763 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr7_-_127837242 0.760 NM_000883
NM_001102605
NM_001142576
NM_183243
IMPDH1



IMP (inosine 5'-monophosphate) dehydrogenase 1



chr5_+_176446425 0.759 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr16_+_65756179 0.758 HSF4
heat shock transcription factor 4
chr19_+_11327061 0.757 NM_001170635
NM_022737
LPPR2

lipid phosphate phosphatase-related protein type 2

chr9_+_130491291 0.755 NM_003011
SET
SET nuclear oncogene
chr5_-_176833259 0.754 NM_004395
DBN1
drebrin 1
chr12_+_54910767 0.754 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr16_+_2504001 0.753 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr7_-_100331417 0.751 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr19_-_1518875 0.736 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr19_+_60487345 0.735 NM_032430
BRSK1
BR serine/threonine kinase 1
chr20_+_34523231 0.735 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr4_+_1764802 0.732 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr16_+_28413421 0.729 NM_018690
APOBR
apolipoprotein B receptor
chr19_-_6453224 0.728 NM_006087
TUBB4
tubulin, beta 4
chr11_-_65070625 0.727 LTBP3
latent transforming growth factor beta binding protein 3
chr1_-_149698272 0.726 POGZ
pogo transposable element with ZNF domain
chr6_+_44203335 0.726 NM_018426
TMEM63B
transmembrane protein 63B
chr7_+_101860958 0.723 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr12_+_56206692 0.722 MBD6
methyl-CpG binding domain protein 6
chr17_+_71097147 0.721 MYO15B
myosin XVB pseudogene
chr12_+_56230110 0.719 NM_004984
KIF5A
kinesin family member 5A
chr9_+_130223046 0.717 CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_7607852 0.710


chr6_-_159159186 0.708 EZR
ezrin
chr17_+_74582597 0.707 NM_001042573
ENGASE
endo-beta-N-acetylglucosaminidase
chr6_-_159159257 0.707 NM_003379
EZR
ezrin
chr2_+_42128521 0.706 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_+_15609009 0.704 EFHD2
EF-hand domain family, member D2
chr10_+_86078136 0.704 NM_018999
FAM190B
family with sequence similarity 190, member B
chr19_+_40224457 0.702 HPN
hepsin
chr22_-_17546234 0.701 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr15_+_63948823 0.701 NM_004663
RAB11A
RAB11A, member RAS oncogene family
chr19_+_40900965 0.700 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr17_-_34607257 0.699 NM_000723
NM_199247
NM_199248
CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr17_-_34015631 0.697 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr17_+_26060617 0.696


chr2_+_112529270 0.695 NM_032824
TMEM87B
transmembrane protein 87B
chr11_+_67984758 0.693 NM_001164160
NM_001164161
NM_001164162
NM_001164163
NM_001164164
NM_018312
PPP6R3





protein phosphatase 6, regulatory subunit 3





chr16_-_87280289 0.691 SNAI3
snail homolog 3 (Drosophila)
chr1_-_221383212 0.691 NM_003268
TLR5
toll-like receptor 5
chr1_+_153317887 0.690 NM_004952
EFNA3
ephrin-A3
chr6_-_30762957 0.690 KIAA1949
KIAA1949
chr1_-_239869826 0.687 NM_014322
OPN3
opsin 3
chr19_-_6718417 0.687 NM_005490
SH2D3A
SH2 domain containing 3A
chr1_+_199259664 0.686


chr19_-_51829778 0.686 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr19_-_44503328 0.685


chr19_-_2672337 0.684 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr18_+_75256931 0.683 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr9_+_130491370 0.682 SET
SET nuclear oncogene
chr1_-_27802688 0.682 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr20_-_60963390 0.682 NM_006602
TCFL5
transcription factor-like 5 (basic helix-loop-helix)
chr22_-_17659183 0.681 NM_001835
NM_007098
CLTCL1

clathrin, heavy chain-like 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 5.07e-23 GO:0009987 cellular process
1.17 3.68e-19 GO:0044260 cellular macromolecule metabolic process
1.13 4.20e-19 GO:0044237 cellular metabolic process
1.11 1.94e-14 GO:0050794 regulation of cellular process
1.24 4.96e-14 GO:0006464 protein modification process
1.09 1.58e-13 GO:0065007 biological regulation
1.10 1.09e-12 GO:0008152 metabolic process
1.23 1.13e-12 GO:0043412 macromolecule modification
1.09 1.91e-12 GO:0050789 regulation of biological process
1.13 2.70e-12 GO:0043170 macromolecule metabolic process
1.11 3.00e-12 GO:0044238 primary metabolic process
1.15 7.62e-10 GO:0060255 regulation of macromolecule metabolic process
1.18 1.24e-09 GO:0044267 cellular protein metabolic process
1.14 4.99e-09 GO:0016043 cellular component organization
1.14 5.83e-09 GO:0031323 regulation of cellular metabolic process
1.13 2.39e-08 GO:0080090 regulation of primary metabolic process
1.12 3.63e-08 GO:0019222 regulation of metabolic process
1.16 3.73e-08 GO:0048518 positive regulation of biological process
1.16 7.31e-08 GO:0048522 positive regulation of cellular process
1.13 1.90e-07 GO:0071840 cellular component organization or biogenesis
1.20 2.17e-07 GO:0006996 organelle organization
1.15 3.07e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 6.55e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.25 1.40e-06 GO:0006793 phosphorus metabolic process
1.25 1.40e-06 GO:0006796 phosphate metabolic process
1.14 2.63e-06 GO:0071842 cellular component organization at cellular level
1.26 8.35e-06 GO:0016310 phosphorylation
1.16 1.27e-05 GO:0048523 negative regulation of cellular process
1.39 1.29e-05 GO:0016568 chromatin modification
1.12 1.88e-05 GO:0006807 nitrogen compound metabolic process
1.14 2.43e-05 GO:0010468 regulation of gene expression
1.29 2.53e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.12 2.74e-05 GO:0034641 cellular nitrogen compound metabolic process
1.45 3.18e-05 GO:0016567 protein ubiquitination
1.15 3.93e-05 GO:0090304 nucleic acid metabolic process
1.13 4.56e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.14 6.06e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.47 6.73e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.26 6.83e-05 GO:0006468 protein phosphorylation
1.38 8.77e-05 GO:0070647 protein modification by small protein conjugation or removal
1.51 1.24e-04 GO:0016569 covalent chromatin modification
1.41 1.29e-04 GO:0032446 protein modification by small protein conjugation
1.13 1.37e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.14 1.41e-04 GO:0051252 regulation of RNA metabolic process
1.51 1.85e-04 GO:0016570 histone modification
1.23 2.55e-04 GO:0006351 transcription, DNA-dependent
1.24 2.76e-04 GO:0051128 regulation of cellular component organization
1.23 2.87e-04 GO:0033554 cellular response to stress
1.27 3.11e-04 GO:0051726 regulation of cell cycle
1.16 3.91e-04 GO:0023051 regulation of signaling
1.21 4.05e-04 GO:0032268 regulation of cellular protein metabolic process
1.12 4.20e-04 GO:0009889 regulation of biosynthetic process
1.17 4.28e-04 GO:0009966 regulation of signal transduction
1.12 4.60e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12 4.60e-04 GO:0031326 regulation of cellular biosynthetic process
1.13 5.26e-04 GO:0048519 negative regulation of biological process
1.11 5.86e-04 GO:0019538 protein metabolic process
1.20 8.25e-04 GO:0051246 regulation of protein metabolic process
1.24 8.45e-04 GO:0016192 vesicle-mediated transport
1.15 1.05e-03 GO:0010467 gene expression
1.31 1.57e-03 GO:0007243 intracellular protein kinase cascade
1.31 1.57e-03 GO:0023014 signal transduction via phosphorylation event
1.41 1.96e-03 GO:0051129 negative regulation of cellular component organization
1.38 1.96e-03 GO:0061061 muscle structure development
1.17 3.21e-03 GO:0035556 intracellular signal transduction
1.14 3.73e-03 GO:0016070 RNA metabolic process
1.11 3.94e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.28 4.19e-03 GO:0006325 chromatin organization
1.41 4.25e-03 GO:0045786 negative regulation of cell cycle
1.10 4.39e-03 GO:0051179 localization
1.19 4.85e-03 GO:0007049 cell cycle
1.18 5.14e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.15 5.96e-03 GO:0007399 nervous system development
1.16 6.73e-03 GO:0033036 macromolecule localization
1.38 6.77e-03 GO:0000165 MAPKKK cascade
1.12 8.13e-03 GO:0006355 regulation of transcription, DNA-dependent
1.10 8.75e-03 GO:0048856 anatomical structure development
1.68 9.84e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.27 1.09e-02 GO:0043549 regulation of kinase activity
1.20 1.26e-02 GO:0022402 cell cycle process
1.26 1.30e-02 GO:0051338 regulation of transferase activity
1.19 1.36e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.23 1.42e-02 GO:0051276 chromosome organization
1.17 1.45e-02 GO:0044248 cellular catabolic process
1.16 1.49e-02 GO:0009893 positive regulation of metabolic process
1.65 1.83e-02 GO:0000209 protein polyubiquitination
1.41 1.98e-02 GO:0007517 muscle organ development
1.10 2.21e-02 GO:0006810 transport
1.18 2.34e-02 GO:0009892 negative regulation of metabolic process
1.10 2.42e-02 GO:0051234 establishment of localization
1.20 2.42e-02 GO:0031399 regulation of protein modification process
1.15 2.47e-02 GO:0009056 catabolic process
1.16 2.92e-02 GO:0031325 positive regulation of cellular metabolic process
1.33 3.24e-02 GO:0006366 transcription from RNA polymerase II promoter
1.18 3.38e-02 GO:0050793 regulation of developmental process
1.18 3.50e-02 GO:0010605 negative regulation of macromolecule metabolic process
1.08 3.53e-02 GO:0051716 cellular response to stimulus
1.22 3.58e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.26 3.75e-02 GO:0045859 regulation of protein kinase activity
1.18 4.05e-02 GO:0048468 cell development
1.17 4.50e-02 GO:0022607 cellular component assembly
1.19 4.85e-02 GO:0008219 cell death
1.08 4.96e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 6.40e-50 GO:0044424 intracellular part
1.10 2.07e-49 GO:0005622 intracellular
1.13 3.00e-39 GO:0043227 membrane-bounded organelle
1.13 8.03e-39 GO:0043231 intracellular membrane-bounded organelle
1.11 2.66e-37 GO:0043226 organelle
1.11 5.06e-37 GO:0043229 intracellular organelle
1.13 6.37e-33 GO:0005737 cytoplasm
1.15 1.06e-24 GO:0005634 nucleus
1.13 1.79e-20 GO:0044444 cytoplasmic part
1.13 1.41e-16 GO:0044422 organelle part
1.13 1.51e-16 GO:0044446 intracellular organelle part
1.23 4.63e-16 GO:0005829 cytosol
1.21 1.39e-13 GO:0044428 nuclear part
1.21 1.50e-11 GO:0031981 nuclear lumen
1.25 5.63e-11 GO:0005654 nucleoplasm
1.03 2.43e-09 GO:0044464 cell part
1.03 2.75e-09 GO:0005623 cell
1.17 3.06e-09 GO:0070013 intracellular organelle lumen
1.17 4.90e-09 GO:0043233 organelle lumen
1.16 2.65e-08 GO:0031974 membrane-enclosed lumen
1.18 1.76e-06 GO:0012505 endomembrane system
1.12 1.88e-05 GO:0043234 protein complex
1.24 9.95e-05 GO:0044451 nucleoplasm part
1.24 1.12e-04 GO:0031988 membrane-bounded vesicle
1.13 1.14e-04 GO:0031090 organelle membrane
1.10 1.60e-04 GO:0032991 macromolecular complex
1.23 1.75e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.20 1.80e-04 GO:0005794 Golgi apparatus
1.22 3.18e-04 GO:0031410 cytoplasmic vesicle
1.25 4.30e-04 GO:0044431 Golgi apparatus part
1.21 9.24e-04 GO:0031982 vesicle
1.64 1.27e-03 GO:0000790 nuclear chromatin
1.10 2.18e-03 GO:0043228 non-membrane-bounded organelle
1.10 2.18e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.56 3.49e-03 GO:0005925 focal adhesion
1.32 5.35e-03 GO:0015629 actin cytoskeleton
1.52 6.31e-03 GO:0030055 cell-substrate junction
1.57 7.39e-03 GO:0042470 melanosome
1.57 7.39e-03 GO:0048770 pigment granule
1.20 8.03e-03 GO:0015630 microtubule cytoskeleton
1.22 9.10e-03 GO:0030054 cell junction
1.40 1.28e-02 GO:0044454 nuclear chromosome part
1.51 1.45e-02 GO:0005924 cell-substrate adherens junction
1.24 1.47e-02 GO:0000139 Golgi membrane
1.43 2.23e-02 GO:0000151 ubiquitin ligase complex
1.34 2.85e-02 GO:0000228 nuclear chromosome
1.37 3.12e-02 GO:0031252 cell leading edge
1.14 4.88e-02 GO:0005783 endoplasmic reticulum

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 4.26e-40 GO:0005515 protein binding
1.08 4.83e-33 GO:0005488 binding
1.33 3.32e-10 GO:0019899 enzyme binding
1.18 3.56e-10 GO:0000166 nucleotide binding
1.30 4.11e-10 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.31 1.06e-09 GO:0016301 kinase activity
1.31 7.31e-09 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.39 3.52e-08 GO:0004674 protein serine/threonine kinase activity
1.33 7.36e-08 GO:0004672 protein kinase activity
1.18 6.43e-07 GO:0016740 transferase activity
1.32 2.94e-06 GO:0008092 cytoskeletal protein binding
1.16 7.47e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.16 1.24e-05 GO:0032553 ribonucleotide binding
1.16 1.24e-05 GO:0032555 purine ribonucleotide binding
1.11 1.34e-05 GO:0003676 nucleic acid binding
1.16 1.38e-05 GO:0017076 purine nucleotide binding
1.17 1.74e-05 GO:0030554 adenyl nucleotide binding
1.17 2.02e-05 GO:0032559 adenyl ribonucleotide binding
1.17 2.22e-05 GO:0005524 ATP binding
1.44 4.24e-05 GO:0019900 kinase binding
1.73 1.09e-04 GO:0031625 ubiquitin protein ligase binding
1.31 1.11e-04 GO:0019904 protein domain specific binding
1.08 1.28e-04 GO:0003824 catalytic activity
1.46 1.38e-04 GO:0019901 protein kinase binding
1.12 3.62e-04 GO:0003677 DNA binding
1.42 4.02e-04 GO:0004842 ubiquitin-protein ligase activity
1.32 4.53e-04 GO:0000988 protein binding transcription factor activity
1.32 4.53e-04 GO:0000989 transcription factor binding transcription factor activity
1.40 5.26e-04 GO:0019787 small conjugating protein ligase activity
1.32 6.05e-04 GO:0003712 transcription cofactor activity
1.34 7.16e-04 GO:0003779 actin binding
1.19 1.47e-03 GO:0001071 nucleic acid binding transcription factor activity
1.19 1.47e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 2.48e-03 GO:0008134 transcription factor binding
1.18 2.83e-03 GO:0030528 transcription regulator activity
1.26 4.21e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.26 5.22e-03 GO:0030695 GTPase regulator activity
1.37 8.21e-03 GO:0003713 transcription coactivator activity
1.20 1.52e-02 GO:0043565 sequence-specific DNA binding
1.29 3.63e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.40 3.75e-02 GO:0000287 magnesium ion binding
1.31 4.49e-02 GO:0016881 acid-amino acid ligase activity