Motif ID: PATZ1.p2

Z-value: 1.699


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_30072217-0.401.4e-01Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_150305933 3.151 NM_000238
NM_172056
 KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr11_+_65049102 2.310 NM_001048218
NM_020680
 SCYL1

SCY1-like 1 (S. cerevisiae)

chr9_+_132961723 2.155 AIF1L
allograft inflammatory factor 1-like
chr22_+_18081968 2.071 NM_002688
 SEPT5
septin 5
chr22_-_21231421 2.005 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
 PRAME




preferentially expressed antigen in melanoma




chr11_+_65049152 1.913 SCYL1
SCY1-like 1 (S. cerevisiae)
chr19_-_53950458 1.910 NM_000148
 FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr5_+_172193826 1.862 NM_001031711
 ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr6_+_33495824 1.848 NM_006772
 SYNGAP1
synaptic Ras GTPase activating protein 1
chr7_-_150306169 1.844 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr9_+_132961683 1.642 NM_001185095
NM_001185096
NM_031426
 AIF1L


allograft inflammatory factor 1-like


chr19_+_45728207 1.635 NM_025213
 SPTBN4
spectrin, beta, non-erythrocytic 4
chr21_+_43267703 1.598 NM_004571
 PKNOX1
PBX/knotted 1 homeobox 1
chr21_+_43267760 1.559 PKNOX1
PBX/knotted 1 homeobox 1
chr19_+_53951155 1.500 NM_019113
 FGF21
fibroblast growth factor 21
chr22_-_17489912 1.487 NM_001173533
NM_001173534
NM_001184781
NM_005137
 DGCR2



DiGeorge syndrome critical region gene 2



chr16_+_2503676 1.474 NM_001198569
NM_001694
 ATP6V0C

ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c

chr22_-_17489718 1.441 DGCR2
DiGeorge syndrome critical region gene 2
chr1_+_111963920 1.426 NM_001010935
NM_002884
 RAP1A

RAP1A, member of RAS oncogene family

chr20_+_30813851 1.398 NM_006892
NM_175848
NM_175849
 DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 103 entries
enrichment   p-value GO term description
1.68 9.84e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.65 1.83e-02 GO:0000209 protein polyubiquitination
1.51 1.24e-04 GO:0016569 covalent chromatin modification
1.51 1.85e-04 GO:0016570 histone modification
1.47 6.73e-05 GO:0048011 nerve growth factor receptor signaling pathway
1.45 3.18e-05 GO:0016567 protein ubiquitination
1.41 1.29e-04 GO:0032446 protein modification by small protein conjugation
1.41 1.96e-03 GO:0051129 negative regulation of cellular component organization
1.41 4.25e-03 GO:0045786 negative regulation of cell cycle
1.41 1.98e-02 GO:0007517 muscle organ development
1.39 1.29e-05 GO:0016568 chromatin modification
1.38 8.77e-05 GO:0070647 protein modification by small protein conjugation or removal
1.38 1.96e-03 GO:0061061 muscle structure development
1.38 6.77e-03 GO:0000165 MAPKKK cascade
1.36 6.55e-07 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.33 3.24e-02 GO:0006366 transcription from RNA polymerase II promoter
1.31 1.57e-03 GO:0007243 intracellular protein kinase cascade
1.31 1.57e-03 GO:0023014 signal transduction via phosphorylation event
1.29 2.53e-05 GO:0007167 enzyme linked receptor protein signaling pathway
1.28 4.19e-03 GO:0006325 chromatin organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 48 entries
enrichment   p-value GO term description
1.64 1.27e-03 GO:0000790 nuclear chromatin
1.57 7.39e-03 GO:0042470 melanosome
1.57 7.39e-03 GO:0048770 pigment granule
1.56 3.49e-03 GO:0005925 focal adhesion
1.52 6.31e-03 GO:0030055 cell-substrate junction
1.51 1.45e-02 GO:0005924 cell-substrate adherens junction
1.43 2.23e-02 GO:0000151 ubiquitin ligase complex
1.40 1.28e-02 GO:0044454 nuclear chromosome part
1.37 3.12e-02 GO:0031252 cell leading edge
1.34 2.85e-02 GO:0000228 nuclear chromosome
1.32 5.35e-03 GO:0015629 actin cytoskeleton
1.25 5.63e-11 GO:0005654 nucleoplasm
1.25 4.30e-04 GO:0044431 Golgi apparatus part
1.24 9.95e-05 GO:0044451 nucleoplasm part
1.24 1.12e-04 GO:0031988 membrane-bounded vesicle
1.24 1.47e-02 GO:0000139 Golgi membrane
1.23 4.63e-16 GO:0005829 cytosol
1.23 1.75e-04 GO:0016023 cytoplasmic membrane-bounded vesicle
1.22 3.18e-04 GO:0031410 cytoplasmic vesicle
1.22 9.10e-03 GO:0030054 cell junction

Gene overrepresentation in function category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
1.73 1.09e-04 GO:0031625 ubiquitin protein ligase binding
1.46 1.38e-04 GO:0019901 protein kinase binding
1.44 4.24e-05 GO:0019900 kinase binding
1.42 4.02e-04 GO:0004842 ubiquitin-protein ligase activity
1.40 5.26e-04 GO:0019787 small conjugating protein ligase activity
1.40 3.75e-02 GO:0000287 magnesium ion binding
1.39 3.52e-08 GO:0004674 protein serine/threonine kinase activity
1.37 8.21e-03 GO:0003713 transcription coactivator activity
1.34 7.16e-04 GO:0003779 actin binding
1.34 2.48e-03 GO:0008134 transcription factor binding
1.33 3.32e-10 GO:0019899 enzyme binding
1.33 7.36e-08 GO:0004672 protein kinase activity
1.32 2.94e-06 GO:0008092 cytoskeletal protein binding
1.32 4.53e-04 GO:0000988 protein binding transcription factor activity
1.32 4.53e-04 GO:0000989 transcription factor binding transcription factor activity
1.32 6.05e-04 GO:0003712 transcription cofactor activity
1.31 1.06e-09 GO:0016301 kinase activity
1.31 7.31e-09 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.31 1.11e-04 GO:0019904 protein domain specific binding
1.31 4.49e-02 GO:0016881 acid-amino acid ligase activity