Motif ID: PAX5.p2

Z-value: 1.755


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_370243580.401.4e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_61742111 2.437 NM_020828
 ZFP28
zinc finger protein 28 homolog (mouse)
chr1_-_233879617 2.072 NM_001098722
 GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr16_-_66827449 1.198 NM_024939
 ESRP2
epithelial splicing regulatory protein 2
chr3_+_133923758 1.192 NCRNA00119
non-protein coding RNA 119
chr10_+_135042684 1.144 NM_152911
NM_207127
NM_207128
 PAOX


polyamine oxidase (exo-N4-amino)


chr15_-_50375143 1.021 NM_018728
 MYO5C
myosin VC
chr19_+_8180179 0.924 NM_024552
 LASS4
LAG1 homolog, ceramide synthase 4
chr20_-_38751289 0.883 NM_005461
 MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr17_-_59131194 0.878 LIMD2
LIM domain containing 2
chr16_-_265868 0.847 NM_003834
NM_183337
 RGS11

regulator of G-protein signaling 11

chr22_-_49317408 0.830 ODF3B
outer dense fiber of sperm tails 3B
chr13_+_43845977 0.799 NM_001010897
 SERP2
stress-associated endoplasmic reticulum protein family member 2
chr10_+_88506320 0.793 NM_004329
 BMPR1A
bone morphogenetic protein receptor, type IA
chr11_-_60819273 0.779 NM_152718
 VWCE
von Willebrand factor C and EGF domains
chr2_-_25328452 0.754 NM_153759
 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_+_8059267 0.753 NM_177972
 TUB
tubby homolog (mouse)
chr7_-_38637475 0.743 AMPH
amphiphysin
chr1_-_233880676 0.710 NM_001098721
NM_004485
 GNG4

guanine nucleotide binding protein (G protein), gamma 4

chr5_+_17270474 0.707 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1
chr2_-_128149112 0.705 NM_001136037
NM_001161403
 LIMS2

LIM and senescent cell antigen-like domains 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 74 entries
enrichment   p-value GO term description
1.74 1.35e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.64 3.74e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.45 2.49e-04 GO:0060284 regulation of cell development
1.44 9.19e-06 GO:0009968 negative regulation of signal transduction
1.40 1.08e-04 GO:0010648 negative regulation of cell communication
1.39 1.52e-04 GO:0023057 negative regulation of signaling
1.38 1.07e-03 GO:0007409 axonogenesis
1.37 1.91e-02 GO:0007411 axon guidance
1.36 1.41e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.36 3.15e-04 GO:0000904 cell morphogenesis involved in differentiation
1.36 1.42e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.36 2.10e-03 GO:0048812 neuron projection morphogenesis
1.35 5.68e-04 GO:0032990 cell part morphogenesis
1.35 7.13e-04 GO:0048858 cell projection morphogenesis
1.33 1.90e-03 GO:0006753 nucleoside phosphate metabolic process
1.33 1.90e-03 GO:0009117 nucleotide metabolic process
1.32 6.30e-07 GO:0022008 neurogenesis
1.32 3.86e-04 GO:0032989 cellular component morphogenesis
1.32 7.68e-04 GO:0000902 cell morphogenesis
1.32 3.04e-03 GO:0051253 negative regulation of RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.63 9.95e-03 GO:0005925 focal adhesion
1.58 2.12e-02 GO:0030055 cell-substrate junction
1.58 2.70e-02 GO:0005924 cell-substrate adherens junction
1.55 2.64e-03 GO:0005912 adherens junction
1.50 4.46e-03 GO:0070161 anchoring junction
1.38 4.16e-03 GO:0015629 actin cytoskeleton
1.32 1.23e-03 GO:0000139 Golgi membrane
1.29 5.64e-04 GO:0044431 Golgi apparatus part
1.22 7.92e-04 GO:0005794 Golgi apparatus
1.20 9.71e-06 GO:0012505 endomembrane system
1.19 5.35e-07 GO:0005829 cytosol
1.14 1.93e-03 GO:0031090 organelle membrane
1.12 9.12e-23 GO:0005737 cytoplasm
1.12 1.58e-12 GO:0044444 cytoplasmic part
1.10 7.30e-07 GO:0005634 nucleus
1.08 2.08e-21 GO:0005622 intracellular
1.08 8.15e-20 GO:0044424 intracellular part
1.08 9.80e-11 GO:0043227 membrane-bounded organelle
1.08 2.01e-10 GO:0043231 intracellular membrane-bounded organelle
1.08 2.92e-04 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.34 8.20e-04 GO:0019904 protein domain specific binding
1.31 3.14e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.31 3.76e-03 GO:0030695 GTPase regulator activity
1.29 2.47e-04 GO:0043565 sequence-specific DNA binding
1.24 4.24e-04 GO:0030234 enzyme regulator activity
1.21 6.11e-03 GO:0030528 transcription regulator activity
1.11 1.72e-12 GO:0005515 protein binding
1.05 5.41e-09 GO:0005488 binding