Motif ID: PAX5.p2

Z-value: 1.755


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_370243580.401.4e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_61742111 2.437 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr1_-_233879617 2.072 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr16_-_66827449 1.198 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr3_+_133923758 1.192 NCRNA00119
non-protein coding RNA 119
chr10_+_135042684 1.144 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr15_-_50375143 1.021 NM_018728
MYO5C
myosin VC
chr19_+_8180179 0.924 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr20_-_38751289 0.883 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr17_-_59131194 0.878 LIMD2
LIM domain containing 2
chr16_-_265868 0.847 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr22_-_49317408 0.830 ODF3B
outer dense fiber of sperm tails 3B
chr13_+_43845977 0.799 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr10_+_88506320 0.793 NM_004329
BMPR1A
bone morphogenetic protein receptor, type IA
chr11_-_60819273 0.779 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr2_-_25328452 0.754 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_+_8059267 0.753 NM_177972
TUB
tubby homolog (mouse)
chr7_-_38637475 0.743 AMPH
amphiphysin
chr1_-_233880676 0.710 NM_001098721
NM_004485
GNG4

guanine nucleotide binding protein (G protein), gamma 4

chr5_+_17270474 0.707 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr2_-_128149112 0.705 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr11_+_22171150 0.692 NM_001142649
NM_213599
ANO5

anoctamin 5

chr2_+_238265617 0.670 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr3_-_133923992 0.669 NPHP3-ACAD11
NPHP3-ACAD11 read-through transcript
chr1_+_15957832 0.663 NM_017556
FBLIM1
filamin binding LIM protein 1
chr13_-_27572646 0.656 NM_004119
FLT3
fms-related tyrosine kinase 3
chr11_-_60819110 0.650 VWCE
von Willebrand factor C and EGF domains
chr7_-_38637513 0.641 NM_001635
NM_139316
AMPH

amphiphysin

chr1_-_6468600 0.632 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr5_+_175725050 0.618 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr7_+_45894480 0.599 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr8_-_144722141 0.596 C8orf73
chromosome 8 open reading frame 73
chr2_-_215382537 0.595 NM_000465
BARD1
BRCA1 associated RING domain 1
chr5_+_167889123 0.592


chr10_+_50488352 0.592 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr2_+_235525355 0.590 NM_014521
SH3BP4
SH3-domain binding protein 4
chr22_-_41913002 0.589 TTLL12
tubulin tyrosine ligase-like family, member 12
chr18_-_68685789 0.584 NM_138966
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr17_+_40192072 0.582 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr19_+_39664706 0.581 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr10_-_105604942 0.580 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr8_-_103320178 0.571 NM_001172477
NM_001172478
NM_015713
RRM2B


ribonucleotide reductase M2 B (TP53 inducible)


chr19_-_51168396 0.566 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr14_+_99329198 0.564 NM_001008707
NM_004434
EML1

echinoderm microtubule associated protein like 1

chr22_-_36153449 0.558 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr11_+_129190942 0.556 NM_138788
TMEM45B
transmembrane protein 45B
chr14_+_89597860 0.555 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr2_-_127694123 0.555 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr17_+_27617307 0.548 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr21_+_45888001 0.546 PCBP3
poly(rC) binding protein 3
chr2_+_70981233 0.545 VAX2
ventral anterior homeobox 2
chr12_+_13044604 0.543 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr2_+_70981223 0.542 NM_012476
VAX2
ventral anterior homeobox 2
chr7_-_19123787 0.539 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr4_+_72271218 0.539 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr4_-_42353640 0.536 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr2_+_238265519 0.534 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr12_-_13044448 0.534 HEBP1
heme binding protein 1
chr3_-_49289285 0.531 NM_198562
C3orf62
chromosome 3 open reading frame 62
chr21_-_43671355 0.527 NM_173354
SIK1
salt-inducible kinase 1
chr10_+_42892506 0.526 NM_020630
NM_020975
RET

ret proto-oncogene

chr2_-_20075889 0.519 MATN3
matrilin 3
chr13_+_87122778 0.518 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr13_+_110565587 0.517 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr2_-_45090025 0.512 NM_016932
SIX2
SIX homeobox 2
chr17_-_16336204 0.510 NM_001113567
NM_207387
C17orf76

chromosome 17 open reading frame 76

chr12_-_13044467 0.510 NM_015987
HEBP1
heme binding protein 1
chr8_-_26427304 0.501 NM_007257
PNMA2
paraneoplastic antigen MA2
chr7_-_1465633 0.500 NM_182924
MICALL2
MICAL-like 2
chr8_+_1909437 0.490 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr1_-_6468108 0.489 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr11_-_133786935 0.489 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr7_-_19123765 0.488 TWIST1
twist homolog 1 (Drosophila)
chr2_-_20075929 0.485 NM_002381
MATN3
matrilin 3
chr20_-_61933012 0.481 ZBTB46
zinc finger and BTB domain containing 46
chr5_+_43228083 0.480 NM_153361
MGC42105
serine/threonine-protein kinase NIM1
chr5_+_17270781 0.477 BASP1
brain abundant, membrane attached signal protein 1
chr7_-_117300763 0.477 NM_033427
CTTNBP2
cortactin binding protein 2
chr10_-_7491204 0.475 NM_001018039
SFMBT2
Scm-like with four mbt domains 2
chr8_+_26427378 0.475 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr6_+_17389752 0.471 NM_001143942
RBM24
RNA binding motif protein 24
chr1_-_3517918 0.470 NM_001409
MEGF6
multiple EGF-like-domains 6
chr11_+_66643311 0.470 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr3_+_32255158 0.469 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr16_+_65018316 0.464 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr22_+_42751487 0.464 NM_013327
PARVB
parvin, beta
chr3_-_127558747 0.463 NM_014079
KLF15
Kruppel-like factor 15
chr17_+_41217391 0.461 NM_001145146
NM_001145147
NM_001145148
NM_004382
CRHR1



corticotropin releasing hormone receptor 1



chr5_-_114533448 0.461 TRIM36
tripartite motif containing 36
chr11_-_65443015 0.461 NM_001135635
NM_031450
C11orf68

chromosome 11 open reading frame 68

chr17_-_16335809 0.459 C17orf76
chromosome 17 open reading frame 76
chr8_+_31616809 0.458 NM_013962
NRG1
neuregulin 1
chr1_-_2333863 0.457 NM_002617
NM_153818
PEX10

peroxisomal biogenesis factor 10

chr5_-_16232896 0.456 NM_001102562
MARCH11
membrane-associated ring finger (C3HC4) 11
chr1_-_2333800 0.455 PEX10
peroxisomal biogenesis factor 10
chr3_-_171786468 0.454 NM_020949
SLC7A14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr19_-_47619992 0.453 LIPE
lipase, hormone-sensitive
chr22_-_41913076 0.452 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr6_+_19945578 0.451 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr16_+_87047418 0.451 NM_153813
ZFPM1
zinc finger protein, multitype 1
chr15_+_99237527 0.448 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr7_-_123460722 0.443 NM_001136002
TMEM229A
transmembrane protein 229A
chr22_+_48966394 0.441 TRABD
TraB domain containing
chr12_-_13044314 0.440 HEBP1
heme binding protein 1
chrX_-_99873152 0.440 NM_001174068
NM_080737
SYTL4

synaptotagmin-like 4

chr17_-_74433048 0.439 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_7891884 0.438 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr15_-_20637731 0.435 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr19_+_60543032 0.435 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr8_+_145221973 0.432 CYC1
cytochrome c-1
chr17_-_1341599 0.431 NM_033375
MYO1C
myosin IC
chr22_-_41913075 0.430 TTLL12
tubulin tyrosine ligase-like family, member 12
chr22_-_39964001 0.428 CHADL
chondroadherin-like
chr13_+_34414390 0.427 NM_015678
NBEA
neurobeachin
chr6_+_36206239 0.427 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr13_-_43351825 0.426 NM_144974
CCDC122
coiled-coil domain containing 122
chr1_+_30964199 0.424 LOC100129196
hypothetical LOC100129196
chr9_+_139892049 0.422 NM_000718
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr12_+_50686990 0.417 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr10_-_30064600 0.415 NM_003174
SVIL
supervillin
chr15_-_20638283 0.414 NM_001142275
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr8_-_41774296 0.414 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr3_+_53170254 0.413 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr19_+_50004134 0.411 NM_001013257
NM_005581
BCAM

basal cell adhesion molecule (Lutheran blood group)

chr2_+_112612429 0.409 NM_001128165
NM_153214
FBLN7

fibulin 7

chr3_-_127677400 0.409 ZXDC
ZXD family zinc finger C
chr10_+_129595349 0.405 PTPRE
protein tyrosine phosphatase, receptor type, E
chr3_+_49211936 0.404 NM_001135197
CCDC36
coiled-coil domain containing 36
chr19_-_53516962 0.403 CCDC114
coiled-coil domain containing 114
chr20_-_36322587 0.403 NM_001029864
KIAA1755
KIAA1755
chr9_-_6635564 0.402 NM_000170
GLDC
glycine dehydrogenase (decarboxylating)
chr10_-_82106479 0.401 NM_138812
DYDC1
DPY30 domain containing 1
chr5_-_179712920 0.401 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr1_-_1465602 0.400 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr10_-_71575953 0.400 TYSND1
trypsin domain containing 1
chr11_+_7997366 0.398 TUB
tubby homolog (mouse)
chr10_-_131652364 0.398 EBF3
early B-cell factor 3
chr3_-_135231417 0.396 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr22_+_48966480 0.394 NM_025204
TRABD
TraB domain containing
chr7_-_1465487 0.393 MICALL2
MICAL-like 2
chr6_-_165996031 0.391 LOC100132188
LP7097
chr8_-_71478560 0.389 NM_006540
NCOA2
nuclear receptor coactivator 2
chr21_+_46473494 0.389 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr15_-_58477407 0.388 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr22_-_28041474 0.387 RASL10A
RAS-like, family 10, member A
chr17_-_60986905 0.387 AXIN2
axin 2
chr16_+_66244314 0.386 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr17_+_77582774 0.384 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr21_+_36993302 0.383


chr3_+_120904555 0.381 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr4_-_5945596 0.379 NM_001014809
CRMP1
collapsin response mediator protein 1
chr5_-_168660293 0.378 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr3_-_53054999 0.376 SFMBT1
Scm-like with four mbt domains 1
chr2_+_27163114 0.375 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr16_+_65790514 0.373 NM_024712
ELMO3
engulfment and cell motility 3
chr19_-_16599986 0.372 NM_004831
MED26
mediator complex subunit 26
chr5_-_58370693 0.372 NM_001197221
NM_001197222
PDE4D

phosphodiesterase 4D, cAMP-specific

chr2_+_9532087 0.371 NM_001039613
IAH1
isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae)
chr9_-_91302707 0.371 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr9_-_90983195 0.369 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr10_-_88116181 0.369 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr17_-_24068759 0.369 NM_001144942
NM_031934
RAB34

RAB34, member RAS oncogene family

chr16_-_1761504 0.368 NME3
non-metastatic cells 3, protein expressed in
chr22_-_28041650 0.368 NM_001007279
NM_006477
RASL10A

RAS-like, family 10, member A

chr11_-_45643711 0.367 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr18_+_17076166 0.367 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr8_-_145661545 0.366 NM_032687
NM_001129888
CYHR1

cysteine/histidine-rich 1

chr22_+_48951286 0.364 NM_001160300
NM_052839
PANX2

pannexin 2

chr1_+_6407403 0.364 NM_031475
ESPN
espin
chr1_-_48235148 0.363 NM_001194986
LOC388630
UPF0632 protein A
chrX_+_68641802 0.361 NM_015686
FAM155B
family with sequence similarity 155, member B
chr6_-_89884324 0.361 NM_080743
SRSF12
serine/arginine-rich splicing factor 12
chr17_-_6887965 0.360 NM_153357
SLC16A11
solute carrier family 16, member 11 (monocarboxylic acid transporter 11)
chr19_+_34994701 0.360 NM_001238
CCNE1
cyclin E1
chr20_-_43974092 0.358 NM_006227
NM_182676
PLTP

phospholipid transfer protein

chr22_-_49292886 0.358 LMF2
lipase maturation factor 2
chr3_+_32255215 0.358 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr22_+_29938145 0.356 LIMK2
LIM domain kinase 2
chr17_-_1029758 0.356 NM_021962
ABR
active BCR-related gene
chr20_+_1154763 0.356 NM_001136566
RAD21L1
RAD21-like 1 (S. pombe)
chr14_-_37134050 0.354 FOXA1
forkhead box A1
chr8_-_143692814 0.352 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr13_-_109236897 0.352 NM_003749
IRS2
insulin receptor substrate 2
chr7_-_158073121 0.349 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr9_-_139437534 0.349 NM_017820
EXD3
exonuclease 3'-5' domain containing 3
chr20_+_52525538 0.348 NM_018431
DOK5
docking protein 5
chr13_+_43351968 0.348 NM_153218
C13orf31
chromosome 13 open reading frame 31
chr7_+_5289079 0.347 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr17_-_45562112 0.345 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr7_-_107883929 0.344 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr4_-_177950658 0.341 NM_005429
VEGFC
vascular endothelial growth factor C
chr11_+_1367665 0.340 NM_003957
BRSK2
BR serine/threonine kinase 2
chr9_+_138497767 0.340 NM_152571
C9orf163
chromosome 9 open reading frame 163
chr16_-_76026431 0.340 NM_199355
ADAMTS18
ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr6_+_137285071 0.338 NM_001008783
SLC35D3
solute carrier family 35, member D3
chr1_+_243200251 0.337 NM_001143943
EFCAB2
EF-hand calcium binding domain 2
chr8_+_38950824 0.336 NM_153692
HTRA4
HtrA serine peptidase 4
chr11_-_112851051 0.336 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr14_-_29466562 0.334 NM_002742
PRKD1
protein kinase D1
chr8_-_144583718 0.334 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr5_+_68824143 0.333 OCLN
occludin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 8.93e-15 GO:0009987 cellular process
1.11 8.92e-13 GO:0065007 biological regulation
1.12 2.15e-12 GO:0050794 regulation of cellular process
1.11 8.75e-12 GO:0050789 regulation of biological process
1.21 1.67e-08 GO:0048523 negative regulation of cellular process
1.24 1.80e-07 GO:0023051 regulation of signaling
1.25 4.79e-07 GO:0007399 nervous system development
1.32 6.30e-07 GO:0022008 neurogenesis
1.20 7.48e-07 GO:0048869 cellular developmental process
1.18 1.29e-06 GO:0048519 negative regulation of biological process
1.28 2.21e-06 GO:0010646 regulation of cell communication
1.20 2.82e-06 GO:0030154 cell differentiation
1.44 9.19e-06 GO:0009968 negative regulation of signal transduction
1.30 1.03e-05 GO:0048699 generation of neurons
1.16 1.72e-05 GO:0048518 positive regulation of biological process
1.12 2.03e-05 GO:0051716 cellular response to stimulus
1.17 2.41e-05 GO:0048522 positive regulation of cellular process
1.13 2.50e-05 GO:0023052 signaling
1.13 3.50e-05 GO:0032502 developmental process
1.22 3.96e-05 GO:0009966 regulation of signal transduction
1.08 4.45e-05 GO:0008152 metabolic process
1.09 4.81e-05 GO:0044237 cellular metabolic process
1.13 6.57e-05 GO:0016043 cellular component organization
1.28 6.61e-05 GO:0048468 cell development
1.40 1.08e-04 GO:0010648 negative regulation of cell communication
1.26 1.26e-04 GO:0032879 regulation of localization
1.29 1.36e-04 GO:0051128 regulation of cellular component organization
1.36 1.41e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.39 1.52e-04 GO:0023057 negative regulation of signaling
1.13 2.39e-04 GO:0007275 multicellular organismal development
1.45 2.49e-04 GO:0060284 regulation of cell development
1.31 3.10e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.36 3.15e-04 GO:0000904 cell morphogenesis involved in differentiation
1.13 3.28e-04 GO:0007165 signal transduction
1.08 3.69e-04 GO:0044238 primary metabolic process
1.32 3.86e-04 GO:0032989 cellular component morphogenesis
1.30 4.29e-04 GO:0030182 neuron differentiation
1.35 5.68e-04 GO:0032990 cell part morphogenesis
1.35 7.13e-04 GO:0048858 cell projection morphogenesis
1.11 7.38e-04 GO:0019222 regulation of metabolic process
1.32 7.68e-04 GO:0000902 cell morphogenesis
1.20 8.47e-04 GO:0009653 anatomical structure morphogenesis
1.38 1.07e-03 GO:0007409 axonogenesis
1.26 1.22e-03 GO:0016265 death
1.36 1.42e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.26 1.49e-03 GO:0008219 cell death
1.12 1.61e-03 GO:0071840 cellular component organization or biogenesis
1.33 1.90e-03 GO:0006753 nucleoside phosphate metabolic process
1.33 1.90e-03 GO:0009117 nucleotide metabolic process
1.36 2.10e-03 GO:0048812 neuron projection morphogenesis
1.13 2.40e-03 GO:0048731 system development
1.12 2.83e-03 GO:0048856 anatomical structure development
1.11 2.93e-03 GO:0051179 localization
1.32 3.04e-03 GO:0051253 negative regulation of RNA metabolic process
1.11 3.09e-03 GO:0031323 regulation of cellular metabolic process
1.31 3.26e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.64 3.74e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.29 3.82e-03 GO:0030030 cell projection organization
1.32 5.19e-03 GO:0048585 negative regulation of response to stimulus
1.32 6.68e-03 GO:0031175 neuron projection development
1.30 7.46e-03 GO:0048666 neuron development
1.31 8.28e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.16 1.02e-02 GO:0048583 regulation of response to stimulus
1.13 1.03e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.74 1.35e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
1.11 1.44e-02 GO:0080090 regulation of primary metabolic process
1.13 1.71e-02 GO:0071842 cellular component organization at cellular level
1.37 1.91e-02 GO:0007411 axon guidance
1.11 2.18e-02 GO:0006807 nitrogen compound metabolic process
1.28 2.19e-02 GO:0010629 negative regulation of gene expression
1.11 2.37e-02 GO:0034641 cellular nitrogen compound metabolic process
1.32 2.52e-02 GO:0072521 purine-containing compound metabolic process
1.17 4.04e-02 GO:0009056 catabolic process
1.29 4.88e-02 GO:0007417 central nervous system development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.12 9.12e-23 GO:0005737 cytoplasm
1.08 2.08e-21 GO:0005622 intracellular
1.08 8.15e-20 GO:0044424 intracellular part
1.12 1.58e-12 GO:0044444 cytoplasmic part
1.08 9.80e-11 GO:0043227 membrane-bounded organelle
1.07 1.69e-10 GO:0043226 organelle
1.08 2.01e-10 GO:0043231 intracellular membrane-bounded organelle
1.07 3.22e-10 GO:0043229 intracellular organelle
1.19 5.35e-07 GO:0005829 cytosol
1.03 6.50e-07 GO:0005623 cell
1.10 7.30e-07 GO:0005634 nucleus
1.03 8.00e-07 GO:0044464 cell part
1.20 9.71e-06 GO:0012505 endomembrane system
1.08 2.92e-04 GO:0044422 organelle part
1.08 3.08e-04 GO:0044446 intracellular organelle part
1.29 5.64e-04 GO:0044431 Golgi apparatus part
1.22 7.92e-04 GO:0005794 Golgi apparatus
1.32 1.23e-03 GO:0000139 Golgi membrane
1.14 1.93e-03 GO:0031090 organelle membrane
1.55 2.64e-03 GO:0005912 adherens junction
1.38 4.16e-03 GO:0015629 actin cytoskeleton
1.50 4.46e-03 GO:0070161 anchoring junction
1.63 9.95e-03 GO:0005925 focal adhesion
1.58 2.12e-02 GO:0030055 cell-substrate junction
1.58 2.70e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.72e-12 GO:0005515 protein binding
1.05 5.41e-09 GO:0005488 binding
1.29 2.47e-04 GO:0043565 sequence-specific DNA binding
1.24 4.24e-04 GO:0030234 enzyme regulator activity
1.34 8.20e-04 GO:0019904 protein domain specific binding
1.31 3.14e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.31 3.76e-03 GO:0030695 GTPase regulator activity
1.21 6.11e-03 GO:0030528 transcription regulator activity