Motif ID: PAX6.p2

Z-value: 0.648


Transcription factors associated with PAX6.p2:

Gene SymbolEntrez IDGene Name
PAX6 5080 paired box 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX6chr11_-_31796061-0.283.2e-01Click!


Activity profile for motif PAX6.p2.

activity profile for motif PAX6.p2


Sorted Z-values histogram for motif PAX6.p2

Sorted Z-values for motif PAX6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 183 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_165564904 1.716 NM_001198783
 POU2F1
POU class 2 homeobox 1
chr1_+_165565006 1.681 POU2F1
POU class 2 homeobox 1
chr6_-_131333173 1.671 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr10_+_35934343 1.087 NM_153368
 GJD4
gap junction protein, delta 4, 40.1kDa
chr5_-_135259403 1.069 NM_000590
 IL9
interleukin 9
chr6_-_42270671 0.872 NM_002098
 GUCA1B
guanylate cyclase activator 1B (retina)
chr16_+_70646008 0.763 NM_001126102
NM_005143
 HP

haptoglobin

chr9_+_102380156 0.669 NM_001018116
 MURC
muscle-related coiled-coil protein
chr15_-_48192804 0.610 ATP8B4
ATPase, class I, type 8B, member 4
chr16_+_70654625 0.596 NM_020995
 HPR
haptoglobin-related protein
chr2_+_39000007 0.593 NM_001145451
 ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr15_+_49760841 0.526 NM_001165257
NM_013243
 SCG3

secretogranin III

chr1_-_31117948 0.506 SDC3
syndecan 3
chr5_-_142057692 0.472 NM_001144934
NM_001144935
 FGF1

fibroblast growth factor 1 (acidic)

chr8_+_39911630 0.448 NM_194294
 IDO2
indoleamine 2,3-dioxygenase 2
chr3_-_15538164 0.438 NM_005677
NM_080539
 COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr8_-_21827057 0.415 NM_003974
 DOK2
docking protein 2, 56kDa
chr2_+_170074457 0.395 NM_006063
 KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chrX_-_15242589 0.348 NM_001012428
 ASB11
ankyrin repeat and SOCS box containing 11
chr4_-_174557191 0.343 NM_007281
 SCRG1
stimulator of chondrogenesis 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
13.10 3.72e-03 GO:0032313 regulation of Rab GTPase activity
13.10 3.72e-03 GO:0032483 regulation of Rab protein signal transduction
6.94 1.24e-02 GO:0032318 regulation of Ras GTPase activity
5.99 3.56e-02 GO:0043087 regulation of GTPase activity
5.95 3.74e-02 GO:0033124 regulation of GTP catabolic process
5.65 8.54e-04 GO:0046578 regulation of Ras protein signal transduction
3.82 4.36e-02 GO:0051056 regulation of small GTPase mediated signal transduction

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
12.85 9.38e-04 GO:0005097 Rab GTPase activator activity