Motif ID: PBX1.p2

Z-value: 1.212


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_163084934-0.381.6e-01Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_96726415 2.801 MBNL2
muscleblind-like 2 (Drosophila)
chr13_+_96726197 2.604 MBNL2
muscleblind-like 2 (Drosophila)
chr7_-_27108826 1.823 NM_006735
 HOXA2
homeobox A2
chr6_+_26307691 1.720 NM_003522
 HIST1H2BF
histone cluster 1, H2bf
chr11_-_102174032 1.623 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr21_+_29439768 1.599 C21orf7
chromosome 21 open reading frame 7
chr11_-_102174102 1.546 NM_001145938
NM_002421
 MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr5_+_162797149 1.355 NM_004060
NM_199246
 CCNG1

cyclin G1

chr10_+_124310170 1.319 NM_004406
NM_007329
NM_017579
 DMBT1


deleted in malignant brain tumors 1


chr5_-_89741233 1.283 NM_004365
 CETN3
centrin, EF-hand protein, 3
chr13_-_47510033 1.264 SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr3_+_112934016 1.180 NM_001134437
 PHLDB2
pleckstrin homology-like domain, family B, member 2
chr2_-_189752575 1.157 NM_000393
 COL5A2
collagen, type V, alpha 2
chr6_+_26153590 1.130 NM_003531
 HIST1H3C
histone cluster 1, H3c
chr17_+_8132539 1.095 NM_001177801
NM_001177802
NM_016492
 RANGRF


RAN guanine nucleotide release factor


chr5_-_58607673 1.085 NM_001197220
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_26307418 1.056 NM_021065
NM_003530
 HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr3_-_53139457 1.045 NM_052859
 RFT1
RFT1 homolog (S. cerevisiae)
chr13_+_38159172 1.035 NM_207361
 FREM2
FRAS1 related extracellular matrix protein 2
chr10_+_63092724 1.030 NM_173554
 C10orf107
chromosome 10 open reading frame 107

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
6.85 1.50e-11 GO:0006334 nucleosome assembly
6.76 6.12e-12 GO:0031497 chromatin assembly
6.67 7.74e-13 GO:0065004 protein-DNA complex assembly
6.32 3.59e-12 GO:0071824 protein-DNA complex subunit organization
6.19 1.95e-10 GO:0034728 nucleosome organization
5.58 1.08e-10 GO:0006323 DNA packaging
5.40 9.49e-11 GO:0006333 chromatin assembly or disassembly
4.79 5.72e-09 GO:0071103 DNA conformation change
3.29 4.04e-09 GO:0034622 cellular macromolecular complex assembly
2.76 1.47e-07 GO:0034621 cellular macromolecular complex subunit organization
2.60 5.89e-03 GO:0000280 nuclear division
2.60 5.89e-03 GO:0007067 mitosis
2.52 1.02e-02 GO:0000087 M phase of mitotic cell cycle
2.51 1.09e-02 GO:0048285 organelle fission
2.40 8.03e-08 GO:0071844 cellular component assembly at cellular level
2.36 1.07e-05 GO:0051276 chromosome organization
2.36 6.41e-04 GO:0006325 chromatin organization
2.28 6.51e-06 GO:0065003 macromolecular complex assembly
2.23 1.24e-02 GO:0000279 M phase
2.08 4.40e-05 GO:0043933 macromolecular complex subunit organization

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
8.22 2.57e-11 GO:0000786 nucleosome
5.78 4.07e-09 GO:0032993 protein-DNA complex
2.95 1.14e-04 GO:0000785 chromatin
2.36 6.96e-05 GO:0044427 chromosomal part
2.22 7.47e-05 GO:0005694 chromosome
1.50 1.54e-05 GO:0043228 non-membrane-bounded organelle
1.50 1.54e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.50 2.10e-02 GO:0005856 cytoskeleton
1.28 1.19e-04 GO:0005634 nucleus
1.26 5.45e-04 GO:0044422 organelle part
1.26 7.82e-04 GO:0044446 intracellular organelle part
1.18 3.28e-06 GO:0043229 intracellular organelle
1.18 4.35e-06 GO:0043226 organelle
1.15 2.82e-03 GO:0043231 intracellular membrane-bounded organelle
1.15 3.20e-03 GO:0043227 membrane-bounded organelle
1.12 1.48e-04 GO:0044424 intracellular part
1.12 1.53e-04 GO:0005622 intracellular

Nothing significant found in function category.