Motif ID: POU1F1.p2

Z-value: 1.697


Transcription factors associated with POU1F1.p2:

Gene SymbolEntrez IDGene Name
POU1F1 5449 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU1F1chr3_-_874083010.468.2e-02Click!


Activity profile for motif POU1F1.p2.

activity profile for motif POU1F1.p2


Sorted Z-values histogram for motif POU1F1.p2

Sorted Z-values for motif POU1F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU1F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_59564323 3.022 NM_173801
PLAC1L
placenta-specific 1-like
chr17_-_36232366 2.236 NM_000421
KRT10
keratin 10
chr1_+_149877955 1.956 SNX27
sorting nexin family member 27
chr6_-_52736231 1.841 NM_000846
GSTA2
glutathione S-transferase alpha 2
chr9_+_130056513 1.779


chr4_-_110942783 1.731 NM_000204
CFI
complement factor I
chr12_+_9925354 1.685 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr5_-_75954807 1.551 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr21_-_42659671 1.520 NM_003225
TFF1
trefoil factor 1
chr11_-_16387001 1.519 NM_001145811
SOX6
SRY (sex determining region Y)-box 6
chr7_+_137411717 1.459 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr3_-_139960874 1.424 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr6_+_167456230 1.413 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr4_-_100461530 1.410 NM_000668
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr3_+_153074118 1.383 NM_033050
SUCNR1
succinate receptor 1
chr2_-_77602843 1.348 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr2_+_102136833 1.330 NM_000877
IL1R1
interleukin 1 receptor, type I
chr5_+_141326620 1.317 NM_183399
RNF14
ring finger protein 14
chr18_+_52575442 1.204 WDR7
WD repeat domain 7
chr5_-_41249270 1.192 NM_000065
C6
complement component 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
4.35 2.63e-02 GO:0072376 protein activation cascade
4.11 2.26e-02 GO:0002449 lymphocyte mediated immunity
3.89 4.21e-02 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
3.37 3.27e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
3.11 9.04e-11 GO:0007608 sensory perception of smell
2.94 2.34e-10 GO:0007606 sensory perception of chemical stimulus
2.94 4.17e-02 GO:0002252 immune effector process
2.70 6.99e-03 GO:0002253 activation of immune response
2.37 2.68e-02 GO:0050778 positive regulation of immune response
2.12 1.01e-05 GO:0006955 immune response
2.09 1.99e-02 GO:0050776 regulation of immune response
1.89 8.65e-04 GO:0007600 sensory perception
1.79 1.55e-02 GO:0006952 defense response
1.77 1.20e-04 GO:0002376 immune system process
1.33 7.75e-08 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
9.48 4.88e-03 GO:0042613 MHC class II protein complex
1.38 4.04e-02 GO:0005576 extracellular region
1.37 5.21e-06 GO:0071944 cell periphery
1.36 9.04e-06 GO:0005886 plasma membrane
1.22 8.05e-03 GO:0031224 intrinsic to membrane
1.21 2.36e-02 GO:0016021 integral to membrane
1.19 1.53e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.98 2.51e-02 GO:0003823 antigen binding
3.20 1.14e-11 GO:0004984 olfactory receptor activity
2.25 2.74e-09 GO:0004930 G-protein coupled receptor activity
1.97 3.60e-09 GO:0004888 transmembrane receptor activity
1.72 4.97e-07 GO:0004872 receptor activity
1.57 1.07e-05 GO:0004871 signal transducer activity
1.57 1.07e-05 GO:0060089 molecular transducer activity