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• Activity deltas table
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Motif ID: POU2F1..3.p2

Z-value: 2.169

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr14_-_106064887	7.870		LOC100126583 IGHV3-48 IGHA1 IGHM	hypothetical LOC100126583 immunoglobulin heavy variable 3-48 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chr1_-_153098811	5.855	NM_170782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801	5.585		IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr22_+_20715340	4.744
chr1_+_202000906	4.489	NM_001136190 NM_017773	LAX1	lymphocyte transmembrane adaptor 1
chr1_+_165565006	4.191		POU2F1	POU class 2 homeobox 1
chr1_+_165564904	4.060	NM_001198783	POU2F1	POU class 2 homeobox 1
chr1_+_154386358	4.025	NM_001193301	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr22_+_21340757	3.987
chr1_-_181889070	3.961	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr22_-_22426551	3.912	NM_013378	VPREB3	pre-B lymphocyte 3
chr22_+_21495273	3.640
chr22_+_21370394	3.585		IGL@	immunoglobulin lambda locus
chr22_+_20880159	3.545		IGLV6-57	immunoglobulin lambda variable 6-57
chr14_-_106119742	3.521		IGLJ3 IGHG1	immunoglobulin lambda joining 3 immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_11887265	3.466	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr19_-_18369407	3.440	NM_145256	LRRC25	leucine rich repeat containing 25
chr14_-_106282128	3.437		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_-_40212670	3.304	NM_019027	RBM47	RNA binding motif protein 47
chr14_-_105785639	3.283
chr6_+_53043729	3.195	NM_012347	FBXO9	F-box protein 9
chr17_-_16816113	3.190	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr14_-_106241445	3.131		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr22_+_20316968	3.033	NM_152612	CCDC116	coiled-coil domain containing 116
chr19_-_16111695	2.999
chr17_-_33179118	2.994	NM_000458 NM_001165923	HNF1B	HNF1 homeobox B
chr14_-_106202262	2.950		IGLJ3 IGHA1	immunoglobulin lambda joining 3 immunoglobulin heavy constant alpha 1
chr19_-_19142090	2.947	NM_001145785	MEF2B	myocyte enhancer factor 2B
chr4_-_186970366	2.910	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr22_+_20880112	2.889
chr19_-_19142053	2.799		MEF2B	myocyte enhancer factor 2B
chrX_+_71280758	2.757	NM_207422	FLJ44635	TPT1-like protein
chr14_-_105845570	2.754		IGHA1	immunoglobulin heavy constant alpha 1
chr19_-_16111594	2.743
chr12_+_91620749	2.705	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr5_-_66528330	2.702	NM_005582	CD180	CD180 molecule
chr17_-_59363352	2.636	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr1_+_200246370	2.626		ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr14_-_105589467	2.620		LOC100126583 IGHA1 IGHG1 IGHG2 IGHM	hypothetical LOC100126583 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant mu
chr14_-_105997732	2.563		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_35764588	2.479		FKBP5	FK506 binding protein 5
chr3_-_46043982	2.478	NM_001024644 NM_005283	XCR1	chemokine (C motif) receptor 1
chr12_-_8656705	2.447	NM_020661	AICDA	activation-induced cytidine deaminase
chr17_-_33178987	2.372		HNF1B	HNF1 homeobox B
chr6_-_35764655	2.346	NM_001145776 NM_001145777 NM_004117	FKBP5	FK506 binding protein 5
chrX_-_55037235	2.338	NM_002625	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_+_200246312	2.335	NM_001114309 NM_004433	ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr9_+_94766379	2.314		FGD3	FYVE, RhoGEF and PH domain containing 3
chr22_+_21407066	2.285
chr4_+_184257337	2.270	NM_024949	WWC2	WW and C2 domain containing 2
chr14_-_105796268	2.210		ZCWPW2 IGHV3-23 IGKV3-20	zinc finger, CW type with PWWP domain 2 immunoglobulin heavy variable 3-23 immunoglobulin kappa variable 3-20
chr1_+_204797079	2.209	NM_182665	RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr14_-_106184988	2.190		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_120799411	2.181	NM_015900	PLA1A	phospholipase A1 member A
chr19_+_40541327	2.150	NM_005304	FFAR3	free fatty acid receptor 3
chr22_+_21384862	2.095		IGLV3-21 IGLJ3 IGLC1	immunoglobulin lambda variable 3-21 immunoglobulin lambda joining 3 immunoglobulin lambda constant 1 (Mcg marker)
chr18_+_75967902	2.083	NM_014913	ADNP2	ADNP homeobox 2
chr6_-_31668476	2.062	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr5_-_88155360	2.040	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr3_+_99733432	2.037	NM_005290	GPR15	G protein-coupled receptor 15
chr19_+_14554895	2.031	NM_207390	CLEC17A	C-type lectin domain family 17, member A
chr14_-_23623657	1.964	NM_006177	NRL	neural retina leucine zipper
chr5_-_131907071	1.955	NM_000879	IL5	interleukin 5 (colony-stimulating factor, eosinophil)
chr14_-_105796665	1.939		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr19_-_60611136	1.880	NM_014501	UBE2S	ubiquitin-conjugating enzyme E2S
chr1_+_205736095	1.846	NM_000573 NM_000651	CR1	complement component (3b/4b) receptor 1 (Knops blood group)
chr8_+_86287161	1.818	NM_001083589	E2F5	E2F transcription factor 5, p130-binding
chr3_+_153074118	1.808	NM_033050	SUCNR1	succinate receptor 1
chr3_+_122794859	1.793	NM_016298	FBXO40	F-box protein 40
chr17_+_70495318	1.761	NM_014603	CDR2L	cerebellar degeneration-related protein 2-like
chr14_-_105644300	1.761		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr9_-_139316523	1.754	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr12_-_120270035	1.721		ANAPC5	anaphase promoting complex subunit 5
chr14_-_106330781	1.718		IGHV5-78	immunoglobulin heavy variable 5-78 pseudogene
chr10_+_124897627	1.704	NM_005519	HMX2	H6 family homeobox 2
chrX_+_69591639	1.696	NM_001166278	DLG3	discs, large homolog 3 (Drosophila)
chr14_-_105763152	1.688		IGHV4-31 IGHA1 IGHD IGHG1 IGHG3	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_105862080	1.670		IGHV4-31 IGHA1 IGHD IGHG1 IGHG2 IGHG3 IGHM SCFV	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu single-chain Fv fragment
chr13_-_45640679	1.668		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr5_-_176868483	1.651		DOK3	docking protein 3
chr22_+_21094094	1.638
chr5_-_145875868	1.625	NM_194251	GPR151	G protein-coupled receptor 151
chr17_-_53849888	1.585		RNF43	ring finger protein 43
chr17_+_24394281	1.568		PIPOX	pipecolic acid oxidase
chr14_-_105762742	1.565
chr20_-_60415729	1.556	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr22_+_21065202	1.554
chr1_+_156526182	1.517	NM_001765	CD1C	CD1c molecule
chr22_+_20899155	1.516
chr17_+_77910411	1.516	NM_207459	TEX19	testis expressed 19
chrX_-_24575146	1.514		PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr1_+_18680010	1.492	NM_152375	KLHDC7A	kelch domain containing 7A
chrX_+_117410693	1.487		WDR44	WD repeat domain 44
chr16_-_73365975	1.476		FA2H	fatty acid 2-hydroxylase
chr14_-_105657378	1.473		IGHV4-31	immunoglobulin heavy variable 4-31
chr11_+_117680504	1.440	NM_000733	CD3E	CD3e molecule, epsilon (CD3-TCR complex)
chr22_+_21065134	1.422		LOC100290481	immunoglobulin lambda light chain-like
chr22_+_21006814	1.396
chr3_-_3127057	1.394	NM_000564 NM_175724 NM_175725 NM_175726 NM_175727 NM_175728	IL5RA	interleukin 5 receptor, alpha
chr17_-_34575939	1.394	NM_001143968	ARL5C	ADP-ribosylation factor-like 5C
chr17_-_53849929	1.393	NM_017763	RNF43	ring finger protein 43
chr22_+_21042091	1.389		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr14_-_105542441	1.378		IGLJ3 IGHA1 IGHG1 IGHM	immunoglobulin lambda joining 3 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr16_-_73366200	1.378	NM_024306	FA2H	fatty acid 2-hydroxylase
chr8_+_7789608	1.346	NM_004942	DEFB4A	defensin, beta 4A
chr1_+_204797120	1.345		RASSF5	Ras association (RalGDS/AF-6) domain family member 5
chr12_+_14409875	1.343	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr16_+_23754772	1.339	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chrX_-_24575375	1.337	NM_001163265 NM_004845	PCYT1B	phosphate cytidylyltransferase 1, choline, beta
chr19_-_3922089	1.321		DAPK3	death-associated protein kinase 3
chr22_+_21065207	1.312		IGLJ3	immunoglobulin lambda joining 3
chr6_+_135558572	1.303
chr5_-_75044001	1.285	NM_152408	POC5	POC5 centriolar protein homolog (Chlamydomonas)
chr16_+_23754822	1.284		PRKCB	protein kinase C, beta
chr14_+_22422270	1.275	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr11_+_527521	1.221	NM_198075	LRRC56	leucine rich repeat containing 56
chr6_+_27323458	1.217	NM_005865	PRSS16	protease, serine, 16 (thymus)
chr21_-_35182842	1.205	NM_001001890 NM_001122607	RUNX1	runt-related transcription factor 1
chr17_-_8004671	1.190		VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)
chr7_+_26404711	1.183		LOC441204	hypothetical locus LOC441204
chr3_+_187917791	1.183	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chr7_-_36730525	1.182	NM_001177506 NM_001177507 NM_001637	AOAH	acyloxyacyl hydrolase (neutrophil)
chr7_-_100021658	1.179		LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4
chr21_-_35182873	1.179		RUNX1	runt-related transcription factor 1
chr14_-_105623358	1.164		IGHA1 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_12903145	1.149	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr22_+_21116283	1.119
chr6_+_43247179	1.105		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr12_-_55730125	1.097	NM_005379	MYO1A	myosin IA
chr6_+_43247168	1.094		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr17_+_54997667	1.094	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr14_-_106289751	1.083		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr16_+_23754860	1.079		PRKCB	protein kinase C, beta
chr16_+_28850760	1.076	NM_001178098 NM_001770	CD19	CD19 molecule
chr7_+_94130673	1.075		PEG10	paternally expressed 10
chr6_-_33016561	1.045	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr14_-_105524207	1.040		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_113310796	1.039	NM_000576	IL1B	interleukin 1, beta
chr17_+_60563963	1.032		RGS9	regulator of G-protein signaling 9
chr10_-_97311084	1.031	NM_015385 NM_024991	SORBS1	sorbin and SH3 domain containing 1
chr4_-_74307637	1.025		ANKRD17	ankyrin repeat domain 17
chr17_+_70244553	1.013	NM_001163989	RAB37	RAB37, member RAS oncogene family
chr15_-_38953628	0.995	NM_133639	RHOV	ras homolog gene family, member V
chr17_+_19999784	0.994	NM_001033554 NM_001033555	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1
chrX_-_131375217	0.991	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr22_+_44059491	0.985	NM_001167574 NM_006953	UPK3A	uroplakin 3A
chrX_-_106846924	0.978	NM_004089	TSC22D3	TSC22 domain family, member 3
chr16_+_23754997	0.973		PRKCB	protein kinase C, beta
chr14_-_106270497	0.964		IGHG3	immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106240998	0.952		IGHV1-69 IGHG1	immunoglobulin heavy variable 1-69 immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_-_83071084	0.947	NM_001142702	DLG2	discs, large homolog 2 (Drosophila)
chr5_+_60663842	0.939	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr17_+_60563917	0.934	NM_001081955 NM_001165933 NM_003835	RGS9	regulator of G-protein signaling 9
chr10_-_21847126	0.928
chr6_-_170441493	0.926	NM_005618	DLL1	delta-like 1 (Drosophila)
chr17_-_44249379	0.904	NM_001130918	TTLL6	tubulin tyrosine ligase-like family, member 6
chr19_-_17236522	0.903	NM_031941	USHBP1	Usher syndrome 1C binding protein 1
chr10_-_98021144	0.899	NM_001114094 NM_013314	BLNK	B-cell linker
chr2_+_96790298	0.880	NM_020184	CNNM4	cyclin M4
chr14_-_106170414	0.874		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_-_138862273	0.868
chr10_+_106103503	0.864	NM_001008723	CCDC147	coiled-coil domain containing 147
chrX_-_106846684	0.862		TSC22D3	TSC22 domain family, member 3
chr21_-_10120690	0.852	NM_001187 NM_182484 NM_181704 NM_182481 NM_182482	BAGE BAGE5 BAGE4 BAGE3 BAGE2	B melanoma antigen B melanoma antigen family, member 5 B melanoma antigen family, member 4 B melanoma antigen family, member 3 B melanoma antigen family, member 2
chr6_-_10939095	0.838	NM_005906	MAK	male germ cell-associated kinase
chr6_+_7524691	0.832		DSP	desmoplakin
chr11_-_31789168	0.829		PAX6	paired box 6
chr14_+_63752424	0.828	NM_182910	SYNE2	spectrin repeat containing, nuclear envelope 2
chr17_-_71287417	0.827	NM_005324	H3F3B	H3 histone, family 3B (H3.3B)
chr11_+_22646229	0.807	NM_177553	GAS2	growth arrest-specific 2
chr1_-_2447848	0.805	NM_018216	PANK4	pantothenate kinase 4
chr7_+_77307382	0.801	NM_001127357 NM_001127359 NM_020432	PHTF2	putative homeodomain transcription factor 2
chr2_-_152393209	0.801	NM_001037174 NM_012097 NM_177985	ARL5A	ADP-ribosylation factor-like 5A
chr13_-_102517196	0.793	NM_000452	SLC10A2	solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr22_-_41340886	0.785	NM_032311 NM_178136	POLDIP3	polymerase (DNA-directed), delta interacting protein 3
chr6_+_37511383	0.783
chrX_+_108665665	0.764	NM_018698	NXT2	nuclear transport factor 2-like export factor 2
chr3_-_99236520	0.756	NM_001105580	GABRR3	gamma-aminobutyric acid (GABA) receptor, rho 3
chr14_-_106137250	0.755
chr6_-_25834733	0.752	NM_170745	HIST1H2AA	histone cluster 1, H2aa
chr2_-_157890400	0.752	NM_020711	ERMN	ermin, ERM-like protein
chr16_-_54466709	0.751	NM_001143685 NM_145024	CES5A	carboxylesterase 5A
chr16_-_31135895	0.750	NM_152901	PYDC1	PYD (pyrin domain) containing 1
chr19_-_50779924	0.749	NM_001017989 NM_025136	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr17_-_70639382	0.744	NM_014595	NT5C	5', 3'-nucleotidase, cytosolic
chr4_+_74505710	0.742
chr6_+_32515596	0.740	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr19_+_59820413	0.736	NM_006669	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr17_-_36209672	0.735	NM_181535	KRT28	keratin 28
chr5_-_39306465	0.731		FYB	FYN binding protein
chr6_+_170441715	0.724		FAM120B	family with sequence similarity 120B
chr12_-_47250069	0.717	NM_002289	LALBA	lactalbumin, alpha-
chr2_+_241776596	0.714	NM_001001666 NM_001001891	ANO7	anoctamin 7
chr2_-_152393128	0.714		ARL5A	ADP-ribosylation factor-like 5A
chr4_-_77163609	0.711	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chrX_+_123062143	0.702		STAG2	stromal antigen 2
chr12_+_6819635	0.702	NM_002075	GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3
chr2_-_2313894	0.700	NM_015025	MYT1L	myelin transcription factor 1-like
chr15_-_38387410	0.693	NM_004573	PLCB2	phospholipase C, beta 2
chr6_-_168219380	0.690	NM_001122841	FRMD1	FERM domain containing 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.56	9.76e-06	GO:0006955	immune response
2.13	2.28e-05	GO:0002376	immune system process
1.32	2.41e-03	GO:0050896	response to stimulus
2.11	9.69e-03	GO:0006952	defense response
1.53	1.32e-02	GO:0048518	positive regulation of biological process
2.61	4.11e-02	GO:0045087	innate immune response

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
11.77	5.46e-08	GO:0003823	antigen binding
1.97	1.88e-03	GO:0001071	nucleic acid binding transcription factor activity
1.97	1.88e-03	GO:0003700	sequence-specific DNA binding transcription factor activity