Motif ID: POU2F1..3.p2

Z-value: 2.169


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1655650060.777.4e-04Click!
POU2F2chr19_-_47328399-0.361.9e-01Click!
POU2F3chr11_+_1196161120.029.5e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_106064887 7.870 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr1_-_153098811 5.855 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr7_+_50318801 5.585 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr22_+_20715340 4.744


chr1_+_202000906 4.489 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr1_+_165565006 4.191 POU2F1
POU class 2 homeobox 1
chr1_+_165564904 4.060 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_+_154386358 4.025 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr22_+_21340757 3.987


chr1_-_181889070 3.961 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr22_-_22426551 3.912 NM_013378
VPREB3
pre-B lymphocyte 3
chr22_+_21495273 3.640


chr22_+_21370394 3.585 IGL@
immunoglobulin lambda locus
chr22_+_20880159 3.545 IGLV6-57
immunoglobulin lambda variable 6-57
chr14_-_106119742 3.521 IGLJ3
IGHG1
immunoglobulin lambda joining 3
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_11887265 3.466 NM_001143948
NM_032744
C6orf105

chromosome 6 open reading frame 105

chr19_-_18369407 3.440 NM_145256
LRRC25
leucine rich repeat containing 25
chr14_-_106282128 3.437 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_-_40212670 3.304 NM_019027
RBM47
RNA binding motif protein 47
chr14_-_105785639 3.283



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.61 4.11e-02 GO:0045087 innate immune response
2.56 9.76e-06 GO:0006955 immune response
2.13 2.28e-05 GO:0002376 immune system process
2.11 9.69e-03 GO:0006952 defense response
1.53 1.32e-02 GO:0048518 positive regulation of biological process
1.32 2.41e-03 GO:0050896 response to stimulus

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
11.77 5.46e-08 GO:0003823 antigen binding
1.97 1.88e-03 GO:0001071 nucleic acid binding transcription factor activity
1.97 1.88e-03 GO:0003700 sequence-specific DNA binding transcription factor activity