Motif ID: POU5F1.p2

Z-value: 2.112


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.649.6e-03Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_8756524 5.044 NM_014308
 PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr7_-_76667045 4.600 NM_006682
 FGL2
fibrinogen-like 2
chr14_-_93512818 3.949 ASB2
ankyrin repeat and SOCS box containing 2
chr5_+_140871107 3.734


chr2_+_17861266 3.732 NM_001105569
 MSGN1
mesogenin 1
chr2_+_68815416 3.629 NM_001007231
NM_001166277
 ARHGAP25

Rho GTPase activating protein 25

chr1_-_181889070 3.439 NM_203454
 APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr17_-_33179118 3.299 NM_000458
NM_001165923
 HNF1B

HNF1 homeobox B

chr1_-_153098811 3.216 NM_170782
 KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr14_-_93512647 3.182 ASB2
ankyrin repeat and SOCS box containing 2
chr10_-_98021144 3.101 NM_001114094
NM_013314
 BLNK

B-cell linker

chr2_+_170742900 3.030 NM_001083615
NM_001171642
NM_138995
 MYO3B


myosin IIIB


chr4_-_164754106 2.923 NM_017923
 MARCH1
membrane-associated ring finger (C3HC4) 1
chr17_-_33178987 2.803 HNF1B
HNF1 homeobox B
chr3_+_48239865 2.663 NM_004345
 CAMP
cathelicidin antimicrobial peptide
chr3_+_46370228 2.588 NM_001123041
NM_001123396
 CCR2

chemokine (C-C motif) receptor 2

chr22_+_21359175 2.537 IGLV3-25
immunoglobulin lambda variable 3-25
chr15_-_40537002 2.499 NM_022473
 ZFP106
zinc finger protein 106 homolog (mouse)
chr6_+_167456230 2.487 NM_031409
 CCR6
chemokine (C-C motif) receptor 6
chr17_+_24394281 2.482 PIPOX
pipecolic acid oxidase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 104 entries
enrichment   p-value GO term description
3.12 4.47e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
2.78 3.41e-02 GO:0048706 embryonic skeletal system development
2.36 1.03e-02 GO:0045165 cell fate commitment
2.24 2.30e-02 GO:0009952 anterior/posterior pattern formation
2.23 2.66e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
2.18 3.27e-03 GO:0043193 positive regulation of gene-specific transcription
2.16 4.10e-02 GO:0030900 forebrain development
2.12 2.88e-03 GO:0003002 regionalization
1.99 1.10e-05 GO:0032583 regulation of gene-specific transcription
1.97 1.95e-02 GO:0045596 negative regulation of cell differentiation
1.96 4.30e-02 GO:0045321 leukocyte activation
1.91 3.63e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.90 1.65e-03 GO:0048598 embryonic morphogenesis
1.88 1.20e-02 GO:0051093 negative regulation of developmental process
1.86 5.14e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.84 7.63e-03 GO:0043009 chordate embryonic development
1.82 9.48e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.82 1.12e-02 GO:0009792 embryo development ending in birth or egg hatching
1.82 1.70e-02 GO:0007420 brain development
1.82 2.74e-02 GO:0007389 pattern specification process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.72 6.16e-03 GO:0043005 neuron projection
1.30 1.46e-03 GO:0044459 plasma membrane part
1.25 9.47e-06 GO:0005886 plasma membrane
1.23 3.28e-05 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
5.02 5.86e-04 GO:0001608 nucleotide receptor activity, G-protein coupled
5.02 5.86e-04 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
3.92 1.35e-02 GO:0001614 purinergic nucleotide receptor activity
3.92 1.35e-02 GO:0016502 nucleotide receptor activity
3.49 1.77e-03 GO:0003707 steroid hormone receptor activity
3.29 4.28e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.13 1.21e-14 GO:0043565 sequence-specific DNA binding
1.97 2.47e-02 GO:0000975 regulatory region DNA binding
1.97 2.47e-02 GO:0001067 regulatory region nucleic acid binding
1.97 2.47e-02 GO:0044212 transcription regulatory region DNA binding
1.92 6.96e-04 GO:0016563 transcription activator activity
1.86 7.11e-13 GO:0001071 nucleic acid binding transcription factor activity
1.86 7.11e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.85 9.22e-13 GO:0030528 transcription regulator activity
1.40 2.60e-07 GO:0003677 DNA binding
1.35 2.73e-03 GO:0004872 receptor activity
1.30 6.17e-03 GO:0004871 signal transducer activity
1.30 6.17e-03 GO:0060089 molecular transducer activity
1.25 7.12e-04 GO:0003676 nucleic acid binding