Motif ID: POU5F1.p2

Z-value: 2.112


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_312425930.649.6e-03Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_8756524 5.044 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr7_-_76667045 4.600 NM_006682
FGL2
fibrinogen-like 2
chr14_-_93512818 3.949 ASB2
ankyrin repeat and SOCS box containing 2
chr5_+_140871107 3.734


chr2_+_17861266 3.732 NM_001105569
MSGN1
mesogenin 1
chr2_+_68815416 3.629 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr1_-_181889070 3.439 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr17_-_33179118 3.299 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr1_-_153098811 3.216 NM_170782
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr14_-_93512647 3.182 ASB2
ankyrin repeat and SOCS box containing 2
chr10_-_98021144 3.101 NM_001114094
NM_013314
BLNK

B-cell linker

chr2_+_170742900 3.030 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr4_-_164754106 2.923 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr17_-_33178987 2.803 HNF1B
HNF1 homeobox B
chr3_+_48239865 2.663 NM_004345
CAMP
cathelicidin antimicrobial peptide
chr3_+_46370228 2.588 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr22_+_21359175 2.537 IGLV3-25
immunoglobulin lambda variable 3-25
chr15_-_40537002 2.499 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr6_+_167456230 2.487 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr17_+_24394281 2.482 PIPOX
pipecolic acid oxidase
chr3_+_46370578 2.384 CCR2
chemokine (C-C motif) receptor 2
chr14_-_106249999 2.318 IGHA1
immunoglobulin heavy constant alpha 1
chr5_-_140875591 2.256 DIAPH1
diaphanous homolog 1 (Drosophila)
chrX_-_77801480 2.215 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr9_+_124836666 2.192 NM_005294
GPR21
G protein-coupled receptor 21
chr10_-_97190885 2.190 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr9_-_35608300 2.179 NM_001782
CD72
CD72 molecule
chr12_+_91620749 2.175 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr5_-_66528330 2.166 NM_005582
CD180
CD180 molecule
chr14_-_106240998 2.148 IGHV1-69
IGHG1
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_-_108252200 2.139 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr3_-_52235218 2.138 NM_017442
TLR9
toll-like receptor 9
chr14_-_106241445 2.098 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr1_-_205012348 2.059 NM_000572
IL10
interleukin 10
chr5_+_140870881 2.052


chr6_+_53043729 2.040 NM_012347
FBXO9
F-box protein 9
chr16_+_10878539 1.994 NM_000246
CIITA
class II, major histocompatibility complex, transactivator
chr7_+_18501876 1.934 NM_014707
NM_178423
HDAC9

histone deacetylase 9

chr2_+_173794692 1.922 ZAK
sterile alpha motif and leucine zipper containing kinase AZK
chr3_-_64186151 1.899 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr3_-_58175437 1.891 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr14_-_106064887 1.833 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr10_+_68355797 1.808 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr12_+_6819635 1.798 NM_002075
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr12_-_16649211 1.768 LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_-_22426551 1.755 NM_013378
VPREB3
pre-B lymphocyte 3
chr13_+_110637173 1.724 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr2_+_108751033 1.713 RANBP2
RAN binding protein 2
chr1_-_215329569 1.711 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr10_+_91488704 1.700 KIF20B
kinesin family member 20B
chr15_-_86600658 1.696 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr14_+_63752424 1.691 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr14_-_106154332 1.659 LOC100126583
IGHG1
hypothetical LOC100126583
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106119742 1.656 IGLJ3
IGHG1
immunoglobulin lambda joining 3
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_105804211 1.656 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_5610060 1.644 NM_130390
TRIM34
tripartite motif containing 34
chr18_+_59726183 1.641 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr17_-_39094787 1.632 NM_001040002
MEOX1
mesenchyme homeobox 1
chrX_-_109570113 1.623 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr5_-_124108672 1.611 NM_020747
ZNF608
zinc finger protein 608
chr18_-_54447168 1.611 NM_052947
ALPK2
alpha-kinase 2
chr2_+_88966170 1.605


chr3_+_42107711 1.596 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chrX_-_77469635 1.580 NM_006639
CYSLTR1
cysteinyl leukotriene receptor 1
chr1_-_28376041 1.577 NM_000952
PTAFR
platelet-activating factor receptor
chr11_-_10630408 1.566 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr14_-_106352471 1.537


chr15_-_76313896 1.495 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr5_+_132037271 1.485 NM_000589
NM_172348
IL4

interleukin 4

chr17_-_45617899 1.461 COL1A1
collagen, type I, alpha 1
chr17_+_24394043 1.460 NM_016518
PIPOX
pipecolic acid oxidase
chr22_+_20715340 1.460


chr22_+_21495273 1.451


chr6_+_158654464 1.441 TULP4
tubby like protein 4
chr6_-_130224108 1.433 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr17_+_45617676 1.428


chr2_-_113310796 1.419 NM_000576
IL1B
interleukin 1, beta
chr20_+_19863716 1.415 RIN2
Ras and Rab interactor 2
chr22_+_21340757 1.414


chr3_+_88270951 1.410 NM_018293
ZNF654
zinc finger protein 654
chr3_+_52212969 1.408 ALAS1
aminolevulinate, delta-, synthase 1
chr12_-_14024187 1.401 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr12_-_8656705 1.391 NM_020661
AICDA
activation-induced cytidine deaminase
chr22_-_44828636 1.387 NM_018280
C22orf26
chromosome 22 open reading frame 26
chr3_+_179736917 1.368 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr6_-_32892705 1.347 NM_002120
HLA-DOB
major histocompatibility complex, class II, DO beta
chr1_+_190552744 1.334 NM_001039152
RGS21
regulator of G-protein signaling 21
chr6_+_26291936 1.333 NM_003523
HIST1H2BE
histone cluster 1, H2be
chr19_+_14554895 1.331 NM_207390
CLEC17A
C-type lectin domain family 17, member A
chr1_-_42156957 1.330 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr6_+_158654890 1.325


chr3_-_152478843 1.319 NM_014879
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr6_+_52159143 1.304 NM_002190
IL17A
interleukin 17A
chrX_+_16051344 1.288 NM_005314
GRPR
gastrin-releasing peptide receptor
chr2_+_65517316 1.287 FLJ16124
FLJ16124 protein
chr1_+_208008517 1.284 TRAF3IP3
TRAF3 interacting protein 3
chr6_-_133120587 1.280 NM_004665
VNN2
vanin 2
chr1_+_156526182 1.276 NM_001765
CD1C
CD1c molecule
chr12_-_121767272 1.275 NM_006018
GPR109B
G protein-coupled receptor 109B
chr10_-_116276651 1.264 NM_006720
ABLIM1
actin binding LIM protein 1
chr1_+_27541049 1.256 NM_001193308
NM_032872
SYTL1

synaptotagmin-like 1

chr1_-_156013487 1.243 NM_030764
FCRL2
Fc receptor-like 2
chr5_-_176869943 1.237 NM_001144875
NM_001144876
DOK3

docking protein 3

chr22_+_21094094 1.228


chr16_+_31274020 1.226 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr12_-_103846186 1.223 NM_032148
SLC41A2
solute carrier family 41, member 2
chr1_+_27541086 1.215 SYTL1
synaptotagmin-like 1
chr12_-_121753795 1.214 NM_177551
GPR109A
G protein-coupled receptor 109A
chr2_-_191580567 1.210 STAT1
signal transducer and activator of transcription 1, 91kDa
chr15_+_62578671 1.204 NM_015042
ZNF609
zinc finger protein 609
chr4_+_76700281 1.197 NM_178497
C4orf26
chromosome 4 open reading frame 26
chr11_-_114880275 1.196 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr21_+_38566298 1.192 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr17_-_16816113 1.188 NM_012452
TNFRSF13B
tumor necrosis factor receptor superfamily, member 13B
chr1_-_197173159 1.180 LOC100131234
familial acute myelogenous leukemia related factor
chr14_-_106202262 1.180 IGLJ3
IGHA1
immunoglobulin lambda joining 3
immunoglobulin heavy constant alpha 1
chr14_-_105524207 1.175 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_-_186970366 1.175 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr5_-_36337756 1.175 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chrX_-_106846924 1.174 NM_004089
TSC22D3
TSC22 domain family, member 3
chr1_+_116455898 1.173 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr9_-_34681135 1.161 NM_006274
CCL19
chemokine (C-C motif) ligand 19
chr1_-_180908639 1.160 NM_001102450
NM_033345
RGS8

regulator of G-protein signaling 8

chr16_+_31274030 1.157 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr3_-_113334657 1.149 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr4_+_154397975 1.145 TRIM2
tripartite motif containing 2
chr4_-_110443247 1.142 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr11_-_26700121 1.141 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr3_-_126325132 1.131 SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr12_+_52713098 1.128 NM_018953
HOXC5
homeobox C5
chr19_+_40511909 1.128 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule



chrX_+_69591639 1.125 NM_001166278
DLG3
discs, large homolog 3 (Drosophila)
chr8_+_11388918 1.124 NM_001715
BLK
B lymphoid tyrosine kinase
chr18_-_21184824 1.123


chr11_+_59920062 1.121 NM_001079692
NM_032597
MS4A14

membrane-spanning 4-domains, subfamily A, member 14

chr8_-_102872372 1.115 NCALD
neurocalcin delta
chr1_+_154386358 1.109 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr13_-_98708549 1.109 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr4_+_81325447 1.102 NM_020226
PRDM8
PR domain containing 8
chr5_+_49997489 1.101 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr1_-_42157077 1.084 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr4_-_47534815 1.082 NM_006587
CORIN
corin, serine peptidase
chr6_+_37245860 1.082 NM_002648
PIM1
pim-1 oncogene
chr22_+_28806452 1.076 NM_152510
HORMAD2
HORMA domain containing 2
chr8_-_95289945 1.069 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr6_-_32665409 1.062 NM_002124
HLA-DRB1
HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1
major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr16_+_31273969 1.056 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr10_+_95507555 1.044 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr12_-_13139848 1.038 NM_031289
NM_153823
GSG1

germ cell associated 1

chr12_+_14409875 1.034 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr1_+_61315378 1.033


chr7_+_28418668 1.028 NM_182898
CREB5
cAMP responsive element binding protein 5
chr22_+_21053972 1.024


chr5_-_156468614 1.022 NM_032782
HAVCR2
hepatitis A virus cellular receptor 2
chrX_+_21960841 1.020 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chr6_-_31668476 1.018 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr9_+_131123115 1.018 NM_001012715
C9orf106
chromosome 9 open reading frame 106
chr14_-_105589467 1.013 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr6_-_41276901 1.007 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chrX_-_76700873 1.006 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr5_-_160211623 0.999 NM_025153
ATP10B
ATPase, class V, type 10B
chr1_+_190811479 0.995 NM_002922
RGS1
regulator of G-protein signaling 1
chr7_+_50318801 0.986 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr1_+_117345894 0.980 NM_004258
CD101
CD101 molecule
chr17_-_74231240 0.971 CYTH1
cytohesin 1
chr10_-_103593529 0.962 NM_014591
NM_173191
NM_173192
NM_173193
NM_173195
NM_173197
KCNIP2





Kv channel interacting protein 2





chr10_+_95838801 0.961 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr14_-_106184988 0.958 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_36991189 0.958 NM_001039459
ELMO1
engulfment and cell motility 1
chr7_+_128795178 0.958 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr2_-_215605054 0.958 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr2_-_191723951 0.956 STAT4
signal transducer and activator of transcription 4
chr12_-_16652202 0.952 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr11_-_123130435 0.951 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr6_+_131613196 0.950 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr1_+_200246370 0.944 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_+_129057152 0.939 NM_001040110
NRF1
nuclear respiratory factor 1
chr7_+_128795280 0.935 AHCYL2
adenosylhomocysteinase-like 2
chr4_+_124540114 0.930 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr22_+_21370394 0.926 IGL@
immunoglobulin lambda locus
chr11_+_119616112 0.923 NM_014352
POU2F3
POU class 2 homeobox 3
chr20_+_34937928 0.923 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr4_-_153523113 0.920 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr12_-_101398451 0.917 IGF1
insulin-like growth factor 1 (somatomedin C)
chr1_+_61315516 0.912 NM_001145511
NFIA
nuclear factor I/A
chr8_-_17599438 0.910 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr12_-_10498481 0.905 NM_213657
NM_213658
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr22_-_34886727 0.905 NM_145640
APOL3
apolipoprotein L, 3
chr2_-_191723978 0.898 STAT4
signal transducer and activator of transcription 4
chr10_+_86121526 0.891 FAM190B
family with sequence similarity 190, member B
chr11_-_114593838 0.889 CADM1
cell adhesion molecule 1
chr16_+_68284252 0.887 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr14_-_106038122 0.887 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr15_-_41879426 0.887 NM_001033517
SERINC4
serine incorporator 4
chrX_+_65152004 0.884


chr1_-_239865724 0.880 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr17_+_69781980 0.876 NM_001172810
NM_023036
DNAI2

dynein, axonemal, intermediate chain 2

chr9_+_115382990 0.876 RGS3
regulator of G-protein signaling 3
chr8_+_23157094 0.875 NM_152272
CHMP7
CHMP family, member 7
chr19_+_12995782 0.875 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 1.43e-12 GO:0048731 system development
1.31 5.46e-12 GO:0032501 multicellular organismal process
1.40 1.93e-11 GO:0007275 multicellular organismal development
1.56 2.34e-11 GO:0030154 cell differentiation
1.67 3.20e-11 GO:0007399 nervous system development
1.38 3.60e-11 GO:0032502 developmental process
1.42 4.26e-11 GO:0048856 anatomical structure development
1.53 1.35e-10 GO:0048869 cellular developmental process
1.20 2.32e-09 GO:0065007 biological regulation
1.22 4.87e-09 GO:0050794 regulation of cellular process
1.24 5.70e-09 GO:0050896 response to stimulus
1.51 1.99e-08 GO:0048513 organ development
1.77 3.23e-08 GO:0022008 neurogenesis
1.20 3.79e-08 GO:0050789 regulation of biological process
1.70 3.64e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.44 5.15e-07 GO:0006355 regulation of transcription, DNA-dependent
1.74 5.47e-07 GO:0048699 generation of neurons
1.42 1.05e-06 GO:0051252 regulation of RNA metabolic process
1.39 2.98e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.80 4.84e-06 GO:0010628 positive regulation of gene expression
1.29 5.89e-06 GO:0023052 signaling
1.78 6.05e-06 GO:0030182 neuron differentiation
1.35 7.79e-06 GO:0048518 positive regulation of biological process
1.37 8.38e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.82 9.48e-06 GO:0045893 positive regulation of transcription, DNA-dependent
1.36 1.01e-05 GO:0010468 regulation of gene expression
1.99 1.10e-05 GO:0032583 regulation of gene-specific transcription
1.30 1.59e-05 GO:0060255 regulation of macromolecule metabolic process
1.29 1.68e-05 GO:0080090 regulation of primary metabolic process
1.53 3.27e-05 GO:0002376 immune system process
1.30 3.32e-05 GO:0007165 signal transduction
1.34 3.44e-05 GO:0031326 regulation of cellular biosynthetic process
1.91 3.63e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.33 7.37e-05 GO:0009889 regulation of biosynthetic process
1.61 8.73e-05 GO:0048468 cell development
1.68 1.41e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
1.46 1.42e-04 GO:0009653 anatomical structure morphogenesis
1.27 1.81e-04 GO:0031323 regulation of cellular metabolic process
1.72 1.82e-04 GO:0051254 positive regulation of RNA metabolic process
1.32 2.43e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66 2.60e-04 GO:0006955 immune response
1.73 4.08e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.75 4.26e-04 GO:0048666 neuron development
1.60 4.62e-04 GO:0040011 locomotion
1.36 4.94e-04 GO:0048523 negative regulation of cellular process
1.78 5.63e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.33 6.22e-04 GO:0048522 positive regulation of cellular process
1.76 6.84e-04 GO:0051253 negative regulation of RNA metabolic process
1.30 6.92e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.68 1.09e-03 GO:0030030 cell projection organization
1.62 1.19e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.62 1.30e-03 GO:2000026 regulation of multicellular organismal development
1.66 1.34e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.77 1.41e-03 GO:0007417 central nervous system development
1.38 1.48e-03 GO:0007166 cell surface receptor linked signaling pathway
1.69 1.64e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.60 1.64e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.90 1.65e-03 GO:0048598 embryonic morphogenesis
1.56 1.72e-03 GO:0006351 transcription, DNA-dependent
1.52 1.90e-03 GO:0009605 response to external stimulus
1.64 2.67e-03 GO:0045595 regulation of cell differentiation
2.12 2.88e-03 GO:0003002 regionalization
1.56 3.10e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.22 3.21e-03 GO:0051716 cellular response to stimulus
2.18 3.27e-03 GO:0043193 positive regulation of gene-specific transcription
1.62 3.52e-03 GO:0009890 negative regulation of biosynthetic process
1.62 3.79e-03 GO:0009790 embryo development
1.31 3.86e-03 GO:0048519 negative regulation of biological process
1.55 4.18e-03 GO:0009891 positive regulation of biosynthetic process
1.53 4.51e-03 GO:0050793 regulation of developmental process
1.86 5.14e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.35 5.99e-03 GO:0048583 regulation of response to stimulus
1.65 6.29e-03 GO:0010629 negative regulation of gene expression
1.73 6.41e-03 GO:0031175 neuron projection development
1.84 7.63e-03 GO:0043009 chordate embryonic development
1.22 8.86e-03 GO:0019222 regulation of metabolic process
1.51 8.86e-03 GO:0009611 response to wounding
1.42 9.63e-03 GO:0051239 regulation of multicellular organismal process
1.64 9.99e-03 GO:0009887 organ morphogenesis
1.75 1.01e-02 GO:0048812 neuron projection morphogenesis
2.36 1.03e-02 GO:0045165 cell fate commitment
1.76 1.09e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.82 1.12e-02 GO:0009792 embryo development ending in birth or egg hatching
1.88 1.20e-02 GO:0051093 negative regulation of developmental process
1.77 1.26e-02 GO:0007409 axonogenesis
1.82 1.70e-02 GO:0007420 brain development
1.29 1.84e-02 GO:0042221 response to chemical stimulus
1.97 1.95e-02 GO:0045596 negative regulation of cell differentiation
2.24 2.30e-02 GO:0009952 anterior/posterior pattern formation
1.60 2.34e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.68 2.35e-02 GO:0001775 cell activation
1.47 2.36e-02 GO:0032774 RNA biosynthetic process
1.58 2.54e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.67 2.55e-02 GO:0048858 cell projection morphogenesis
2.23 2.66e-02 GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
1.82 2.74e-02 GO:0007389 pattern specification process
1.08 2.79e-02 GO:0009987 cellular process
2.78 3.41e-02 GO:0048706 embryonic skeletal system development
1.42 3.46e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.66 3.47e-02 GO:0032990 cell part morphogenesis
1.73 3.48e-02 GO:0016477 cell migration
2.16 4.10e-02 GO:0030900 forebrain development
1.96 4.30e-02 GO:0045321 leukocyte activation
3.12 4.47e-02 GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.25 9.47e-06 GO:0005886 plasma membrane
1.23 3.28e-05 GO:0071944 cell periphery
1.30 1.46e-03 GO:0044459 plasma membrane part
1.72 6.16e-03 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.13 1.21e-14 GO:0043565 sequence-specific DNA binding
1.86 7.11e-13 GO:0001071 nucleic acid binding transcription factor activity
1.86 7.11e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.85 9.22e-13 GO:0030528 transcription regulator activity
1.40 2.60e-07 GO:0003677 DNA binding
5.02 5.86e-04 GO:0001608 nucleotide receptor activity, G-protein coupled
5.02 5.86e-04 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
1.92 6.96e-04 GO:0016563 transcription activator activity
1.25 7.12e-04 GO:0003676 nucleic acid binding
3.49 1.77e-03 GO:0003707 steroid hormone receptor activity
1.35 2.73e-03 GO:0004872 receptor activity
3.29 4.28e-03 GO:0004879 ligand-dependent nuclear receptor activity
1.30 6.17e-03 GO:0004871 signal transducer activity
1.30 6.17e-03 GO:0060089 molecular transducer activity
3.92 1.35e-02 GO:0001614 purinergic nucleotide receptor activity
3.92 1.35e-02 GO:0016502 nucleotide receptor activity
1.97 2.47e-02 GO:0000975 regulatory region DNA binding
1.97 2.47e-02 GO:0001067 regulatory region nucleic acid binding
1.97 2.47e-02 GO:0044212 transcription regulatory region DNA binding