Motif ID: POU6F1.p2

Z-value: 1.730


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
POU6F1 5463 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU6F1chr12_-_498782160.243.9e-01Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_166516901 4.798 NM_005149
TBX19
T-box 19
chr22_+_38652555 4.512 GRAP2
GRB2-related adaptor protein 2
chr6_+_7524691 4.168 DSP
desmoplakin
chr4_-_145281237 3.892 NM_002099
GYPA
glycophorin A (MNS blood group)
chr15_-_100280784 3.430 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr1_+_158603480 3.390 NM_005598
NHLH1
nescient helix loop helix 1
chr4_-_145159889 3.296 NM_002100
GYPB
glycophorin B (MNS blood group)
chr1_+_165565006 3.291 POU2F1
POU class 2 homeobox 1
chr1_+_165564904 3.288 NM_001198783
POU2F1
POU class 2 homeobox 1
chr8_-_13018123 3.273 NM_001164271
DLC1
deleted in liver cancer 1
chr11_+_5466490 3.061 NM_001005163
OR52D1
olfactory receptor, family 52, subfamily D, member 1
chr1_+_58899 3.016 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr19_-_54350457 2.997 NM_002152
HRC
histidine rich calcium binding protein
chr3_+_129682434 2.806


chr10_+_94584449 2.799 NM_001013848
EXOC6
exocyst complex component 6
chr17_-_36232366 2.776 NM_000421
KRT10
keratin 10
chrX_-_55074125 2.640 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr19_+_61624 2.621 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr11_+_19328846 2.552 NM_001111018
NAV2
neuron navigator 2
chr7_-_92693716 2.448 NM_001039372
HEPACAM2
HEPACAM family member 2
chrX_+_65299157 2.389 NM_138737
HEPH
hephaestin
chr4_+_71806538 2.371 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr6_-_49942147 2.303 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr3_-_13032130 2.275


chr11_-_123758448 2.187 NM_001005468
OR8B2
olfactory receptor, family 8, subfamily B, member 2
chr3_+_46894239 2.051 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr16_+_33112480 1.929 NM_016212
TP53TG3
TP53 target 3
chr1_-_229071957 1.920 NM_001136494
C1orf198
chromosome 1 open reading frame 198
chr22_+_21116283 1.813


chr9_-_94206648 1.806 NM_014057
NM_033014
OGN

osteoglycin

chr7_-_107667728 1.770 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr3_+_153074118 1.721 NM_033050
SUCNR1
succinate receptor 1
chr16_+_33169015 1.710 NM_016212
TP53TG3
TP53 target 3
chr16_-_32595553 1.616 NM_016212
TP53TG3
TP53 target 3
chr9_+_19280748 1.607 NM_017925
DENND4C
DENN/MADD domain containing 4C
chr6_+_105511615 1.600 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr1_-_158815895 1.581 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr6_-_123999640 1.570 NM_006073
TRDN
triadin
chr20_+_56919233 1.564 GNAS
GNAS complex locus
chr7_+_91762227 1.547


chr5_-_75954807 1.469 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr6_-_138231006 1.465


chr17_-_10362583 1.438 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr19_-_38052481 1.407 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr1_+_109057078 1.393 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr13_+_108079570 1.379 NM_001198950
MYO16
myosin XVI
chr22_+_21065134 1.370 LOC100290481
immunoglobulin lambda light chain-like
chr4_-_44348414 1.368 NM_182592
YIPF7
Yip1 domain family, member 7
chr2_+_128009782 1.364 NM_001080527
MYO7B
myosin VIIB
chr2_-_169596078 1.355 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr1_+_46151845 1.306 MAST2
microtubule associated serine/threonine kinase 2
chr11_-_57173823 1.286 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr22_+_21065202 1.247


chr11_+_69176391 1.238 CCND1
cyclin D1
chr4_-_145046109 1.230 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr1_+_61642287 1.218 NFIA
nuclear factor I/A
chr2_-_180135559 1.217 NM_001113398
ZNF385B
zinc finger protein 385B
chr2_-_157890400 1.215 NM_020711
ERMN
ermin, ERM-like protein
chr2_-_225073357 1.209 CUL3
cullin 3
chr4_+_39874921 1.200 NM_004310
RHOH
ras homolog gene family, member H
chr19_+_44591589 1.188


chr2_+_233099113 1.183 NM_000751
CHRND
cholinergic receptor, nicotinic, delta
chr13_+_112746908 1.178 MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_-_88573949 1.150 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr1_+_559618 1.142


chr13_-_43908937 1.133 TSC22D1
TSC22 domain family, member 1
chr1_-_56750235 1.044 PPAP2B
phosphatidic acid phosphatase type 2B
chr6_+_163904564 1.023 QKI
quaking homolog, KH domain RNA binding (mouse)
chr3_-_57209319 1.022 NM_003865
HESX1
HESX homeobox 1
chr7_-_135263737 1.013 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr20_+_62266217 1.003 MYT1
myelin transcription factor 1
chr7_+_138469029 0.984 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr18_+_45342398 0.968 NM_006033
LIPG
lipase, endothelial
chr5_-_39238818 0.966 FYB
FYN binding protein
chr1_-_41399632 0.952 NM_001031694
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr5_+_140583098 0.947 NM_018934
PCDHB14
protocadherin beta 14
chr5_-_145232723 0.936 NM_001080516
GRXCR2
glutaredoxin, cysteine rich 2
chr6_-_2696152 0.893 NM_001012418
MYLK4
myosin light chain kinase family, member 4
chrX_+_65299352 0.888 HEPH
hephaestin
chr10_+_63331401 0.885 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr12_+_108310906 0.879 NM_001101421
MYO1H
myosin IH
chr3_-_153470022 0.877 LOC401093
hypothetical LOC401093
chr11_-_123772456 0.872 NM_001005467
OR8B3
olfactory receptor, family 8, subfamily B, member 3
chr6_-_127822227 0.870 NM_014702
KIAA0408
KIAA0408
chr12_-_16652202 0.867 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_+_120490054 0.861 C7orf58
chromosome 7 open reading frame 58
chr5_-_86739683 0.850 CCNH
cyclin H
chr18_+_606671 0.839 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr22_-_21193504 0.829 NM_080764
ZNF280B
zinc finger protein 280B
chr5_+_176449156 0.824 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr1_-_161380562 0.821 RGS5
regulator of G-protein signaling 5
chr20_+_62266270 0.818 NM_004535
MYT1
myelin transcription factor 1
chr22_+_21065207 0.816 IGLJ3
immunoglobulin lambda joining 3
chr17_-_36276987 0.807 NM_000223
KRT12
keratin 12
chr1_-_93030538 0.802 NM_005665
EVI5
ecotropic viral integration site 5
chr6_+_53991672 0.796 NM_138569
C6orf142
chromosome 6 open reading frame 142
chr2_+_178893216 0.794 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr13_-_43908991 0.787 TSC22D1
TSC22 domain family, member 1
chr7_+_72034735 0.783 POM121
POM121 membrane glycoprotein
chr13_-_43908985 0.775 TSC22D1
TSC22 domain family, member 1
chr13_-_43908995 0.772 TSC22D1
TSC22 domain family, member 1
chr13_-_43908994 0.771 TSC22D1
TSC22 domain family, member 1
chr5_+_139869819 0.767


chr1_+_224079597 0.755 NM_000120
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr6_+_31604717 0.752 NM_001011700
MCCD1
mitochondrial coiled-coil domain 1
chr16_+_2672527 0.747 KCTD5
potassium channel tetramerisation domain containing 5
chr15_-_48626193 0.741 NM_203494
USP50
ubiquitin specific peptidase 50
chr7_-_50596238 0.726 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr1_+_556968 0.723


chr11_-_16454493 0.719 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr3_-_139960874 0.715 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr13_-_43908972 0.709 NM_006022
TSC22D1
TSC22 domain family, member 1
chr3_-_197726587 0.695 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr7_+_143043871 0.684 NM_001130026
FAM115C
family with sequence similarity 115, member C
chr1_-_158815850 0.683 CD84
CD84 molecule
chr11_+_4965996 0.677 NM_021801
MMP26
matrix metallopeptidase 26
chr3_+_142175329 0.674 SLC25A36
solute carrier family 25, member 36
chr8_-_101384633 0.672 NM_015435
RNF19A
ring finger protein 19A
chr15_+_47502666 0.670 NM_002009
FGF7
fibroblast growth factor 7
chr7_+_129771865 0.670 NM_001127441
NM_001127442
NM_080385
CPA5


carboxypeptidase A5


chr21_+_37714470 0.661 NM_130438
NM_001396
DYRK1A

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A

chr17_+_46176105 0.659 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr3_+_162697289 0.636 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr17_-_10265991 0.629 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr6_-_27988152 0.619 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr10_+_70172257 0.618 CCAR1
cell division cycle and apoptosis regulator 1
chr4_-_164614335 0.617 NM_032136
TKTL2
transketolase-like 2
chr1_-_120189301 0.608 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr2_-_105421661 0.587 NM_201557
FHL2
four and a half LIM domains 2
chr17_-_38087366 0.586 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr7_+_142539291 0.585 NM_002652
PIP
prolactin-induced protein
chr17_-_64462976 0.585 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr1_-_201321711 0.585 MYOG
myogenin (myogenic factor 4)
chr18_-_3209846 0.583 MYOM1
myomesin 1, 185kDa
chr7_+_128136347 0.582 FAM71F1
family with sequence similarity 71, member F1
chr14_-_60022487 0.581 NM_174978
C14orf39
chromosome 14 open reading frame 39
chr1_-_178100204 0.572


chr5_+_140509803 0.568 NM_018939
PCDHB6
protocadherin beta 6
chr17_-_53847937 0.566 RNF43
ring finger protein 43
chr11_+_61943082 0.557 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr2_+_169367345 0.552 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chrX_-_153698930 0.552 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr11_+_71605466 0.551 NM_000803
NM_001113534
NM_001113535
NM_001113536
FOLR2



folate receptor 2 (fetal)



chr4_+_42590038 0.551 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr3_-_198784590 0.544 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr6_-_29163027 0.543 NM_001005226
OR2B3
olfactory receptor, family 2, subfamily B, member 3
chr12_-_69434330 0.536 PTPRR
protein tyrosine phosphatase, receptor type, R
chr17_+_55269974 0.532


chr7_+_106897737 0.531 NM_005295
GPR22
G protein-coupled receptor 22
chr1_-_159543847 0.529 MPZ
myelin protein zero
chr14_-_20128721 0.518 NM_001024822
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr7_+_18296569 0.518 HDAC9
histone deacetylase 9
chr5_+_86712376 0.510


chr12_-_7739591 0.503 NM_020634
GDF3
growth differentiation factor 3
chr11_+_86710076 0.500 TMEM135
transmembrane protein 135
chr7_+_38984133 0.499 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr13_+_108046500 0.493 NM_015011
MYO16
myosin XVI
chr12_-_110410730 0.485 ATXN2
ataxin 2
chr11_+_59564323 0.482 NM_173801
PLAC1L
placenta-specific 1-like
chr16_-_32596378 0.478 NM_001099687
TP53TG3B
TP53 target 3B
chrX_+_123062143 0.471 STAG2
stromal antigen 2
chr8_+_17440664 0.470 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr17_+_20712337 0.469


chr22_+_21370394 0.468 IGL@
immunoglobulin lambda locus
chr11_+_5329313 0.467 NM_001004750
OR51B6
olfactory receptor, family 51, subfamily B, member 6
chr17_-_57023322 0.467 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr6_+_45404031 0.467 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr12_-_49897743 0.464 POU6F1
POU class 6 homeobox 1
chr22_+_21042091 0.461 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr2_-_215953818 0.457 FN1
fibronectin 1
chr14_+_19473606 0.456 NM_001004063
OR4K1
olfactory receptor, family 4, subfamily K, member 1
chr7_-_25234582 0.448 NM_022150
NPVF
neuropeptide VF precursor
chr4_-_153493133 0.445 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr7_+_94130673 0.445 PEG10
paternally expressed 10
chr10_-_13584950 0.442 NM_001100912
NM_152751
BEND7

BEN domain containing 7

chr3_-_114047479 0.442 NM_001008784
CD200R1L
CD200 receptor 1-like
chr16_+_2593351 0.442 LOC652276
hypothetical LOC652276
chr9_+_80134302 0.441 PSAT1
phosphoserine aminotransferase 1
chr2_-_158439868 0.439 NM_001105
ACVR1
activin A receptor, type I
chr11_+_77452550 0.437 NM_003251
THRSP
thyroid hormone responsive
chr12_+_54611212 0.435 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr1_+_74473672 0.432 NM_015978
TNNI3K
TNNI3 interacting kinase
chr7_+_104468614 0.425 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr3_-_121117647 0.424 GSK3B
glycogen synthase kinase 3 beta
chr17_-_37794017 0.422 NM_003150
NM_139276
STAT3

signal transducer and activator of transcription 3 (acute-phase response factor)

chr17_-_52248248 0.420 NM_001085430
C17orf67
chromosome 17 open reading frame 67
chr7_-_112514990 0.419 GPR85
G protein-coupled receptor 85
chr6_+_42896771 0.417 NM_015349
KIAA0240
KIAA0240
chr13_-_45577144 0.416 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr19_-_59295882 0.414 NM_130771
NM_133168
NM_133169
NM_206818
OSCAR



osteoclast associated, immunoglobulin-like receptor



chr6_-_49862858 0.410 NM_138733
PGK2
phosphoglycerate kinase 2
chr1_+_196874839 0.408 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_+_144654565 0.408 NM_007124
UTRN
utrophin
chr1_-_149611768 0.406 NM_003944
SELENBP1
selenium binding protein 1
chr7_-_5533621 0.405 ACTB
actin, beta
chr17_-_10313600 0.404 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr22_+_19458378 0.401 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr5_+_150020595 0.401 NM_001122853
NM_133371
MYOZ3

myozenin 3

chr6_+_29187565 0.401 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr7_-_99864220 0.396 NM_017984
ZCWPW1
zinc finger, CW type with PWWP domain 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.47 5.20e-09 GO:0007606 sensory perception of chemical stimulus
3.40 1.92e-07 GO:0007608 sensory perception of smell
2.34 5.27e-05 GO:0007600 sensory perception
1.37 8.12e-04 GO:0032501 multicellular organismal process
1.76 1.97e-02 GO:0050877 neurological system process
1.65 3.01e-02 GO:0003008 system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.44 4.81e-05 GO:0071944 cell periphery
1.44 9.63e-05 GO:0005886 plasma membrane
3.60 4.92e-02 GO:0044449 contractile fiber part

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.58 2.94e-08 GO:0004930 G-protein coupled receptor activity
3.47 4.83e-08 GO:0004984 olfactory receptor activity
2.02 1.30e-05 GO:0004888 transmembrane receptor activity
1.84 1.89e-05 GO:0004872 receptor activity
1.70 9.74e-05 GO:0004871 signal transducer activity
1.70 9.74e-05 GO:0060089 molecular transducer activity
27.70 2.37e-02 GO:0047023 androsterone dehydrogenase activity
27.70 2.37e-02 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity