Motif ID: PPARG.p2

Z-value: 0.913


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_12304332-0.283.2e-01Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_54361216 3.986 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr8_+_145692916 2.396 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr2_+_218992053 2.388 NM_007127
VIL1
villin 1
chr19_-_60432443 2.238 NM_173804
TMEM86B
transmembrane protein 86B
chr19_-_55708936 1.424 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr1_+_201541241 1.264 BTG2
BTG family, member 2
chr8_-_145613058 1.147 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr8_-_145613034 1.059 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr1_+_201541269 0.909 NM_006763
BTG2
BTG family, member 2
chr19_+_54352809 0.871 NM_001195227
NM_017636
TRPM4

transient receptor potential cation channel, subfamily M, member 4

chr15_-_38908197 0.856 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr10_-_72032519 0.842 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr22_-_21814208 0.835 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr19_-_5821546 0.829 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr17_-_59451662 0.811 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr15_-_88148177 0.808 ANPEP
alanyl (membrane) aminopeptidase
chr1_-_150029529 0.777 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr6_-_31736488 0.738 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr19_+_54352843 0.737 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr7_-_92057597 0.686 NM_001040057
NM_152789
FAM133B

family with sequence similarity 133, member B

chr7_-_92057561 0.595 FAM133B
family with sequence similarity 133, member B
chr22_+_21006814 0.535


chr14_+_23855291 0.531 LTB4R
leukotriene B4 receptor
chr9_-_129564517 0.521 NM_001142532
NM_001142531
SH2D3C

SH2 domain containing 3C

chr8_-_145672525 0.518 NM_003923
FOXH1
forkhead box H1
chr1_-_37991160 0.510 EPHA10
EPH receptor A10
chr7_-_99365178 0.508 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr1_-_94359266 0.503 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_-_28999388 0.481 TRIM27
tripartite motif containing 27
chr10_+_114125927 0.460 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr22_+_21042091 0.455 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr19_+_18312365 0.451 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr16_-_3567354 0.440 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr10_+_114125955 0.430 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114126004 0.425 ACSL5
acyl-CoA synthetase long-chain family member 5
chr11_+_60366004 0.423 NM_024098
CCDC86
coiled-coil domain containing 86
chr19_-_5790702 0.423 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr6_-_52549774 0.400 NM_012288
TRAM2
translocation associated membrane protein 2
chr17_-_37590910 0.396 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr10_-_99042419 0.388 ARHGAP19
Rho GTPase activating protein 19
chr7_-_128330615 0.386 KCP
kielin/chordin-like protein
chr19_-_13074669 0.385 LYL1
lymphoblastic leukemia derived sequence 1
chr10_-_116408046 0.381 NM_002313
ABLIM1
actin binding LIM protein 1
chr6_+_7053863 0.378 RREB1
ras responsive element binding protein 1
chr15_-_74390861 0.374 NM_000126
NM_001127716
ETFA

electron-transfer-flavoprotein, alpha polypeptide

chr22_+_25347927 0.374 NM_001886
CRYBA4
crystallin, beta A4
chr1_-_3806564 0.373 C1orf174
chromosome 1 open reading frame 174
chr19_-_4491024 0.363 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr22_+_20880159 0.359 IGLV6-57
immunoglobulin lambda variable 6-57
chr17_-_59327602 0.337 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr19_-_54618410 0.333 NM_178449
PTH2
parathyroid hormone 2
chr17_-_41658493 0.328 NM_001193465
KIAA1267
KIAA1267
chrX_+_70360184 0.327 GJB1
gap junction protein, beta 1, 32kDa
chr1_-_149955870 0.319 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr19_-_4491078 0.309 LRG1
leucine-rich alpha-2-glycoprotein 1
chr17_+_39603599 0.306 NM_080863
ASB16
ankyrin repeat and SOCS box containing 16
chr19_-_7604569 0.306 NM_174895
PCP2
Purkinje cell protein 2
chr14_+_104117100 0.304 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr9_-_130006309 0.300 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr1_-_152431175 0.298 NM_152263
TPM3
tropomyosin 3
chr12_-_54409710 0.296 CD63
CD63 molecule
chr11_+_46697335 0.288 F2
coagulation factor II (thrombin)
chr10_-_99042381 0.285 NM_032900
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 read-through transcript
Rho GTPase activating protein 19
chr11_+_46697312 0.284 NM_000506
F2
coagulation factor II (thrombin)
chr22_+_20880112 0.279


chr7_+_128367961 0.276 NM_001098627
IRF5
interferon regulatory factor 5
chr7_+_142270634 0.270 EPHB6
EPH receptor B6
chr3_-_129777618 0.268 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr19_+_56337368 0.265 NM_014385
NM_016543
SIGLEC7

sialic acid binding Ig-like lectin 7

chr16_-_28425632 0.265 NM_145659
IL27
interleukin 27
chr1_-_154665807 0.263 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr20_-_62081434 0.263 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr15_-_88148538 0.260 ANPEP
alanyl (membrane) aminopeptidase
chr11_+_46697345 0.260 F2
coagulation factor II (thrombin)
chr6_+_132901119 0.258 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr11_-_67528103 0.258 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr19_-_14085979 0.251 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr14_+_99601498 0.247 NM_016337
EVL
Enah/Vasp-like
chr8_-_107851593 0.240 NM_139166
ABRA
actin-binding Rho activating protein
chr1_+_26389638 0.239 NM_198137
CATSPER4
cation channel, sperm associated 4
chr1_+_68070573 0.239


chr1_+_221955876 0.238 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr16_+_82782223 0.238 NM_001145400
NM_139174
ADAD2

adenosine deaminase domain containing 2

chr17_+_42641712 0.236 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr5_-_179040580 0.235 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr3_+_33815064 0.231 NM_001162429
NM_013374
PDCD6IP

programmed cell death 6 interacting protein

chr10_-_72032447 0.231 PRF1
perforin 1 (pore forming protein)
chr11_-_5212168 0.228 NM_000519
HBD
hemoglobin, delta
chr9_+_139245029 0.227 NM_001177316
NM_001177317
SLC34A3

solute carrier family 34 (sodium phosphate), member 3

chr21_-_42644138 0.227 NM_005423
TFF2
trefoil factor 2
chr17_-_31231421 0.223 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr1_-_158521491 0.222 PEX19
peroxisomal biogenesis factor 19
chr8_-_27392647 0.221 NM_000742
CHRNA2
cholinergic receptor, nicotinic, alpha 2 (neuronal)
chr19_-_54636425 0.220 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr3_+_33815127 0.216 PDCD6IP
programmed cell death 6 interacting protein
chr1_-_158521547 0.215 NM_001193644
NM_002857
PEX19

peroxisomal biogenesis factor 19

chr11_+_384199 0.215 NM_007183
PKP3
plakophilin 3
chr16_+_2901995 0.215 FLYWCH1
FLYWCH-type zinc finger 1
chr11_+_64079665 0.214 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr9_+_101024379 0.213 NM_006808
SEC61B
Sec61 beta subunit
chr19_-_13074973 0.210 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr1_+_19796044 0.209 NM_001032363
C1orf15-NBL1
C1orf151
C1ORF15-NBL1 read-through transcript
chromosome 1 open reading frame 151
chr11_+_268569 0.206 NM_138329
NLRP6
NLR family, pyrin domain containing 6
chr22_+_18388602 0.204 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr1_-_41259973 0.204 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr7_+_30917939 0.203 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr1_+_559618 0.203


chr6_-_52549673 0.199 TRAM2
translocation associated membrane protein 2
chr9_+_130428519 0.199 SPTAN1
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr15_+_72687765 0.194 NM_003992
CLK3
CDC-like kinase 3
chr3_-_110319598 0.194 NM_014429
MORC1
MORC family CW-type zinc finger 1
chr11_-_310775 0.192 NM_021034
IFITM3
interferon induced transmembrane protein 3 (1-8U)
chr1_-_149955415 0.192 NM_001172648
NM_001172649
CELF3

CUGBP, Elav-like family member 3

chr3_+_33815097 0.191 PDCD6IP
programmed cell death 6 interacting protein
chr1_+_19796119 0.191


chr17_+_7474177 0.191 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr15_-_74390846 0.186 ETFA
electron-transfer-flavoprotein, alpha polypeptide
chr1_+_199884072 0.185 NM_020443
NAV1
neuron navigator 1
chr14_+_23700261 0.184 NM_006084
IRF9
interferon regulatory factor 9
chr11_-_73700257 0.182 NM_182904
P4HA3
prolyl 4-hydroxylase, alpha polypeptide III
chr1_-_51757490 0.182 EPS15
epidermal growth factor receptor pathway substrate 15
chr19_-_61396232 0.179 NM_001080456
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr7_-_38341697 0.179 TRGV7
T cell receptor gamma variable 7 pseudogene
chr1_-_6448737 0.177 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr7_-_150561233 0.176


chr11_+_66927976 0.176 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr19_-_44060729 0.173 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr1_-_239869826 0.173 NM_014322
OPN3
opsin 3
chr6_+_31891509 0.169 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr19_+_16860807 0.166 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr16_+_19375272 0.162 NM_024780
TMC5
transmembrane channel-like 5
chr12_-_55791202 0.162 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr10_-_45410197 0.161 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8

chr12_+_56135353 0.161 NM_031479
INHBE
inhibin, beta E
chr20_-_34807882 0.160 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr17_+_71586857 0.159 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr3_-_12680329 0.158 RAF1
v-raf-1 murine leukemia viral oncogene homolog 1
chr19_+_53650577 0.158 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr2_+_231569082 0.157 NM_139073
SPATA3
spermatogenesis associated 3
chr14_+_99601517 0.156 EVL
Enah/Vasp-like
chr11_+_66499323 0.155 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr14_-_74458897 0.154 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr17_+_42686217 0.154 ITGB3
integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
chr22_+_18388633 0.151 C22orf25
chromosome 22 open reading frame 25
chr6_+_31903374 0.148 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr7_-_100262971 0.148 NM_004444
EPHB4
EPH receptor B4
chr22_+_21484240 0.147


chr17_+_16259573 0.146 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr19_+_951295 0.145 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr11_+_66927955 0.144 TBC1D10C
TBC1 domain family, member 10C
chr1_-_3806683 0.144 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr19_-_16875407 0.142 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr3_+_33815081 0.140 PDCD6IP
programmed cell death 6 interacting protein
chr2_+_27200160 0.139 NM_032604
ABHD1
abhydrolase domain containing 1
chr10_-_99042348 0.139 ARHGAP19
Rho GTPase activating protein 19
chr20_+_36365965 0.137 NM_001725
BPI
bactericidal/permeability-increasing protein
chr2_+_119697859 0.134 STEAP3
STEAP family member 3
chr7_+_1543644 0.133 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr7_+_102502852 0.132 ARMC10
armadillo repeat containing 10
chr18_+_27925859 0.131 RNF138
ring finger protein 138
chr22_+_21559959 0.130 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr11_+_65049102 0.129 NM_001048218
NM_020680
SCYL1

SCY1-like 1 (S. cerevisiae)

chr17_+_75319476 0.129 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr11_-_310925 0.129 IFITM3
interferon induced transmembrane protein 3 (1-8U)
chr11_+_384238 0.128 PKP3
plakophilin 3
chr1_-_159435440 0.125 NM_005099
ADAMTS4
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr12_-_94914133 0.125 NM_002108
HAL
histidine ammonia-lyase
chr22_+_48698282 0.124 NM_001135101
NM_024324
CRELD2

cysteine-rich with EGF-like domains 2

chr11_+_5916033 0.122


chr19_+_1389397 0.122 RPS15
ribosomal protein S15
chr3_-_127258299 0.120 NM_001008487
SLC41A3
solute carrier family 41, member 3
chr1_-_21373816 0.117 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr20_+_43996717 0.117 NM_022104
PCIF1
PDX1 C-terminal inhibiting factor 1
chr1_-_31003260 0.117 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr9_-_135140450 0.116 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr2_-_202811459 0.114 NM_001005781
NM_001005782
NM_003352
SUMO1


SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)


chr22_+_21094094 0.113


chr18_+_27925815 0.111 NM_016271
RNF138
ring finger protein 138
chr4_+_110700764 0.111 NM_017918
CCDC109B
coiled-coil domain containing 109B
chr8_+_128875902 0.110 PVT1
Pvt1 oncogene (non-protein coding)
chr17_+_44263370 0.109 NM_005831
CALCOCO2
calcium binding and coiled-coil domain 2
chr9_-_137731139 0.109 NM_001012415
NM_001101677
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr19_-_50517971 0.109 CKM
creatine kinase, muscle
chr12_+_108149558 0.108 ACACB
acetyl-CoA carboxylase beta
chr17_-_39375327 0.107 NM_002722
PPY
pancreatic polypeptide
chr9_-_37582575 0.105 NM_001001790
NM_001134484
NM_001134485
TOMM5


translocase of outer mitochondrial membrane 5 homolog (yeast)


chr15_+_38462213 0.103 NM_001142761
NM_001142762
NM_033286
C15orf23


chromosome 15 open reading frame 23


chr12_+_6807831 0.102 NM_014262
LEPREL2
leprecan-like 2
chr8_-_97316933 0.102 NM_006294
UQCRB
ubiquinol-cytochrome c reductase binding protein
chr1_+_31655607 0.102 NM_001199037
SERINC2
serine incorporator 2
chr1_-_31003181 0.102 LAPTM5
lysosomal protein transmembrane 5
chr13_-_72253970 0.101 DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr19_-_55763091 0.101 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr1_+_178867787 0.099 XPR1
xenotropic and polytropic retrovirus receptor 1
chr9_-_135140425 0.098 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr19_+_54530512 0.097 CD37
CD37 molecule
chr17_-_71747867 0.094 NM_052916
RNF157
ring finger protein 157
chr1_+_201286933 0.090 NM_015053
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr19_-_60611136 0.087 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chrX_+_134895447 0.086 SLC9A6
solute carrier family 9 (sodium/hydrogen exchanger), member 6

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.73 5.96e-03 GO:0044459 plasma membrane part
1.99 1.12e-02 GO:0005887 integral to plasma membrane
1.95 1.64e-02 GO:0031226 intrinsic to plasma membrane
7.25 3.33e-02 GO:0005793 ER-Golgi intermediate compartment

Nothing significant found in function category.