Motif ID: PRRX1,2.p2

Z-value: 4.047


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX1chr1_+_1688988980.761.1e-03Click!
PRRX2chr9_+_131467740-0.253.6e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_17599438 8.906 NM_020749
 MTUS1
microtubule associated tumor suppressor 1
chr20_+_5935897 7.201 NM_001127458
 CRLS1
cardiolipin synthase 1
chr12_-_15706340 7.139 EPS8
epidermal growth factor receptor pathway substrate 8
chr5_+_147775652 7.031 FBXO38
F-box protein 38
chr8_-_82557956 7.009 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr9_+_124835608 6.831 RABGAP1
GPR21
RAB GTPase activating protein 1
G protein-coupled receptor 21
chr5_-_88155360 6.768 NM_001193348
NM_001193349
 MEF2C

myocyte enhancer factor 2C

chr4_+_160408447 6.466 NM_014247
 RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_133145539 6.396 NM_001077427
 LYPD1
LY6/PLAUR domain containing 1
chr9_+_674193 6.173


chr2_-_175170674 5.880 WIPF1
WAS/WASL interacting protein family, member 1
chr10_+_126620681 5.867 NM_017580
 ZRANB1
zinc finger, RAN-binding domain containing 1
chr4_-_152366970 5.832 NM_001009555
NM_001128923
 SH3D19

SH3 domain containing 19

chr3_+_69895310 5.829 NM_001184967
 MITF
microphthalmia-associated transcription factor
chr10_+_69539255 5.750 NM_032578
 MYPN
myopalladin
chr9_-_15240113 5.709 NM_001168342
 TTC39B
tetratricopeptide repeat domain 39B
chr6_-_87861492 5.658 NM_000735
 CGA
glycoprotein hormones, alpha polypeptide
chr8_+_42671718 5.645 NM_000749
 CHRNB3
cholinergic receptor, nicotinic, beta 3
chr4_+_146820805 5.623 NM_001080531
 C4orf51
chromosome 4 open reading frame 51
chr11_-_128399218 5.587 NM_014715
 ARHGAP32
Rho GTPase activating protein 32

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.82 1.14e-03 GO:0007517 muscle organ development
1.59 2.57e-02 GO:0061061 muscle structure development
1.30 4.01e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.19 1.79e-03 GO:0048731 system development
1.18 9.95e-04 GO:0048856 anatomical structure development
1.15 1.32e-02 GO:0007275 multicellular organismal development
1.14 2.00e-02 GO:0032502 developmental process

Nothing significant found in compartment category.

Nothing significant found in function category.