Motif ID: RFX1..5_RFXANK_RFXAP.p2

Z-value: 2.734


Transcription factors associated with RFX1..5_RFXANK_RFXAP.p2:

Gene SymbolEntrez IDGene Name
RFX1 5989 regulatory factor X, 1 (influences HLA class II expression)
RFX2 5990 regulatory factor X, 2 (influences HLA class II expression)
RFX3 5991 regulatory factor X, 3 (influences HLA class II expression)
RFX4 5992 regulatory factor X, 4 (influences HLA class II expression)
RFX5 5993 regulatory factor X, 5 (influences HLA class II expression)
RFXANK 8625 regulatory factor X-associated ankyrin-containing protein
RFXAP 5994 regulatory factor X-associated protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RFX4chr12_+_1055008140.751.3e-03Click!
RFXAPchr13_+_362913060.675.9e-03Click!
RFXANKchr19_+_191640070.381.6e-01Click!
RFX1chr19_-_13977875-0.342.2e-01Click!
RFX3chr9_-_35157210.312.6e-01Click!
RFX5chr1_-_1495862980.253.7e-01Click!
RFX2chr19_-_60614910.087.9e-01Click!


Activity profile for motif RFX1..5_RFXANK_RFXAP.p2.

activity profile for motif RFX1..5_RFXANK_RFXAP.p2


Sorted Z-values histogram for motif RFX1..5_RFXANK_RFXAP.p2

Sorted Z-values for motif RFX1..5_RFXANK_RFXAP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RFX1..5_RFXANK_RFXAP.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_42701460 4.918 CCDC30
coiled-coil domain containing 30
chr2_-_187422141 4.621 NM_182521
ZSWIM2
zinc finger, SWIM-type containing 2
chr18_+_30544193 4.287 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr12_+_120840829 3.530 NM_001178003
NM_144668
WDR66

WD repeat domain 66

chr8_+_13468722 2.971 NM_001007090
C8orf48
chromosome 8 open reading frame 48
chr5_-_157031022 2.939 SOX30
SRY (sex determining region Y)-box 30
chr2_+_228444570 2.893 NM_178821
WDR69
WD repeat domain 69
chr8_+_120497732 2.695 NM_002514
NOV
nephroblastoma overexpressed gene
chr3_-_58538110 2.576 FAM107A
family with sequence similarity 107, member A
chr3_-_114643008 2.572 NM_001164496
NM_018338
WDR52

WD repeat domain 52

chr19_-_63643400 2.570 NM_003433
ZNF132
zinc finger protein 132
chr7_+_48041632 2.428 NM_001100159
C7orf57
chromosome 7 open reading frame 57
chr3_+_120904555 2.412 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr3_-_139315011 2.382 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr5_+_157031138 2.302 NM_001145132
C5orf52
chromosome 5 open reading frame 52
chr12_+_79362256 2.294 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chrX_+_135079120 2.285 NM_001159704
FHL1
four and a half LIM domains 1
chr5_-_142045770 2.280 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chrX_+_135079461 2.256 NM_001167819
FHL1
four and a half LIM domains 1
chr2_+_213857347 2.249 NM_001025436
NM_024532
SPAG16

sperm associated antigen 16


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
13.37 1.87e-02 GO:0035082 axoneme assembly
6.54 7.84e-04 GO:0042384 cilium assembly
4.61 3.26e-02 GO:0060271 cilium morphogenesis
4.58 1.13e-03 GO:0010927 cellular component assembly involved in morphogenesis
4.43 1.56e-04 GO:0030031 cell projection assembly
2.83 4.54e-02 GO:0000226 microtubule cytoskeleton organization
2.69 6.83e-04 GO:0007017 microtubule-based process

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
7.78 1.95e-08 GO:0035085 cilium axoneme
6.66 7.24e-09 GO:0005930 axoneme
6.32 2.19e-05 GO:0005932 microtubule basal body
6.07 4.51e-08 GO:0044441 cilium part
3.97 1.45e-08 GO:0005929 cilium
2.49 5.18e-04 GO:0005874 microtubule
2.22 4.48e-03 GO:0005815 microtubule organizing center
2.09 1.00e-05 GO:0015630 microtubule cytoskeleton
2.07 6.98e-03 GO:0044463 cell projection part
1.67 1.55e-02 GO:0042995 cell projection
1.60 1.54e-02 GO:0044430 cytoskeletal part
1.54 2.60e-03 GO:0005856 cytoskeleton
1.33 2.85e-02 GO:0043228 non-membrane-bounded organelle
1.33 2.85e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.21 1.27e-05 GO:0005737 cytoplasm
1.10 3.09e-02 GO:0005622 intracellular

Nothing significant found in function category.