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• Activity deltas table
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Motif ID: RREB1.p2

Z-value: 3.743

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_96924582	8.505	NM_001172667	FAM178B	family with sequence similarity 178, member B
chr1_-_30977931	6.778		LAPTM5	lysosomal protein transmembrane 5
chr14_+_104244998	5.104		INF2	inverted formin, FH2 and WH2 domain containing
chrX_+_17665483	3.635	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr4_-_809879	3.398	NM_006651	CPLX1	complexin 1
chr19_-_55914837	3.340
chr19_+_540849	2.851	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_-_1731273	2.788
chr10_-_135000464	2.600	NM_015722	CALY	calcyon neuron-specific vesicular protein
chr17_+_1580504	2.507		WDR81	WD repeat domain 81
chr10_-_135000358	2.398		CALY	calcyon neuron-specific vesicular protein
chr2_+_85515428	2.329	NM_198482	SH2D6	SH2 domain containing 6
chr17_+_39741306	2.260	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr10_-_75085754	2.208	NM_001114133	SYNPO2L	synaptopodin 2-like
chr19_-_13910167	2.189	NM_024825	PODNL1	podocan-like 1
chr19_-_16868674	2.165		CPAMD8	C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr3_-_48607596	2.134	NM_000094	COL7A1	collagen, type VII, alpha 1
chr20_-_61574259	2.118	NM_004518 NM_172106 NM_172107 NM_172108 NM_172109	KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2
chr1_-_202647526	2.100	NM_032833	PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr6_-_31668476	2.062	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr19_-_60557875	1.937	NM_144613	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr2_+_170742900	1.930	NM_001083615 NM_001171642 NM_138995	MYO3B	myosin IIIB
chr20_+_55359551	1.746	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr7_+_150390566	1.715		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr17_+_72982919	1.672	NM_001113495	SEPT9	septin 9
chr4_+_191226073	1.671	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr16_-_3225070	1.645	NM_001145447 NM_003454	ZNF200	zinc finger protein 200
chr1_-_154484341	1.641	NM_198406 NM_024897	PAQR6	progestin and adipoQ receptor family member VI
chr1_-_226670928	1.626		TRIM17	tripartite motif containing 17
chr1_-_1525309	1.611		LOC643988	hypothetical LOC643988
chr2_+_219453487	1.603	NM_025216	WNT10A	wingless-type MMTV integration site family, member 10A
chr11_+_61479182	1.594		BEST1	bestrophin 1
chr1_-_1283770	1.571	NM_032348	MXRA8	matrix-remodelling associated 8
chr8_+_144706699	1.551	NM_001166237	GSDMD	gasdermin D
chr8_-_73150371	1.526	NM_007332	TRPA1	transient receptor potential cation channel, subfamily A, member 1
chr11_+_66499323	1.519	NM_001136485	C11orf86	chromosome 11 open reading frame 86
chr20_+_55359706	1.519		RAE1	RAE1 RNA export 1 homolog (S. pombe)
chr1_+_3378030	1.491		ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr19_+_60487578	1.489		BRSK1	BR serine/threonine kinase 1
chr16_-_65516919	1.485	NM_001128850 NM_004165	RRAD	Ras-related associated with diabetes
chr1_-_154318412	1.485	NM_001093725	MEX3A	mex-3 homolog A (C. elegans)
chr5_-_142045770	1.461	NM_000800	FGF1	fibroblast growth factor 1 (acidic)
chr4_+_191239247	1.450	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr12_+_56135353	1.445	NM_031479	INHBE	inhibin, beta E
chr4_+_191235959	1.431	NM_001177376	DUX4L4	double homeobox 4 like 4
chr8_-_145119627	1.388	NM_201378	PLEC	plectin
chr2_+_72998111	1.383	NM_004097	EMX1	empty spiracles homeobox 1
chr19_-_7896974	1.362	NM_206833	CTXN1	cortexin 1
chr8_-_41624030	1.353	NM_152568	NKX6-3	NK6 homeobox 3
chr21_-_45173061	1.342	NM_001127491	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr15_-_86600658	1.335	NM_001007156 NM_001012338 NM_002530	NTRK3	neurotrophic tyrosine kinase, receptor, type 3
chr1_-_226671205	1.330	NM_001024940 NM_001134855 NM_016102	TRIM17	tripartite motif containing 17
chr6_-_32184975	1.326	NM_019105	TNXB	tenascin XB
chr12_+_6807831	1.312	NM_014262	LEPREL2	leprecan-like 2
chr11_+_10433241	1.308	NM_001025389	AMPD3	adenosine monophosphate deaminase 3
chr22_-_49363711	1.307	NM_004377 NM_152246 NM_001145134 NM_001145135 NM_001145136 NM_152245	CPT1B	carnitine palmitoyltransferase 1B (muscle)
chr12_-_47679176	1.307	NM_015086	DDN	dendrin
chr15_-_81037554	1.306	NM_001079533 NM_001079534 NM_001079535	CPEB1	cytoplasmic polyadenylation element binding protein 1
chr1_+_945331	1.306	NM_198576	AGRN	agrin
chr12_-_53071285	1.301	NM_001130967 NM_001130968	ZNF385A	zinc finger protein 385A
chr2_+_149349643	1.292
chr19_-_5291700	1.278	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr11_+_15093059	1.277	NM_001042536	INSC	inscuteable homolog (Drosophila)
chr7_+_100111689	1.246		GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr22_-_37969897	1.236		PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
chr19_-_60352369	1.223	NM_001126132 NM_001126133 NM_003283	TNNT1	troponin T type 1 (skeletal, slow)
chr19_-_60350122	1.220		TNNT1	troponin T type 1 (skeletal, slow)
chr22_+_36286350	1.196	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr2_-_219881937	1.192		PTPRN	protein tyrosine phosphatase, receptor type, N
chr10_-_76538859	1.189	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr20_-_47238310	1.185	NM_001037328 NM_004602 NM_017452 NM_017453 NM_017454	STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)
chr13_-_40138607	1.173	NM_002015	FOXO1	forkhead box O1
chr1_+_221633337	1.165	NM_152610	C1orf65	chromosome 1 open reading frame 65
chr11_-_66961709	1.160	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr1_-_200879203	1.131	NM_001136504	SYT2	synaptotagmin II
chr8_-_125252884	1.129		C8orf78	chromosome 8 open reading frame 78
chr2_-_85490984	1.129		CAPG	capping protein (actin filament), gelsolin-like
chr11_+_122936145	1.126		GRAMD1B	GRAM domain containing 1B
chr19_+_60487345	1.124	NM_032430	BRSK1	BR serine/threonine kinase 1
chr2_+_42649105	1.121	NM_020744	MTA3	metastasis associated 1 family, member 3
chr19_+_10642648	1.114		ILF3	interleukin enhancer binding factor 3, 90kDa
chr12_+_52665196	1.112	NM_017409	HOXC10	homeobox C10
chr19_+_38979502	1.088	NM_001129994 NM_001129995 NM_024076	KCTD15	potassium channel tetramerisation domain containing 15
chr21_+_44560779	1.085		PFKL	phosphofructokinase, liver
chr21_+_42946719	1.083	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr16_-_31347151	1.075	NM_005205	COX6A2	cytochrome c oxidase subunit VIa polypeptide 2
chr11_+_63876924	1.074		CCDC88B	coiled-coil domain containing 88B
chr8_+_99508425	1.067	NM_020697	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr1_-_46853380	1.052	NM_145279	MOBKL2C	MOB1, Mps One Binder kinase activator-like 2C (yeast)
chr2_+_241213334	1.051	NM_005301	GPR35	G protein-coupled receptor 35
chr19_+_811615	1.049		CFD	complement factor D (adipsin)
chr22_-_16127520	1.046		CECR3	cat eye syndrome chromosome region, candidate 3
chr4_-_5941043	1.039		CRMP1	collapsin response mediator protein 1
chr2_-_119322228	1.014	NM_001426	EN1	engrailed homeobox 1
chr17_+_75507750	1.006
chr6_+_34541827	1.002	NM_020804	PACSIN1	protein kinase C and casein kinase substrate in neurons 1
chr19_+_3317589	1.001		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr7_+_134567270	0.996	NM_182489	STRA8	stimulated by retinoic acid gene 8 homolog (mouse)
chr22_-_43986896	0.991		KIAA0930	KIAA0930
chr12_-_51887266	0.987	NM_000889	ITGB7	integrin, beta 7
chrX_-_137621060	0.986		FGF13	fibroblast growth factor 13
chr3_+_50629872	0.982		MAPKAPK3	mitogen-activated protein kinase-activated protein kinase 3
chr4_+_995395	0.978		FGFRL1	fibroblast growth factor receptor-like 1
chr21_+_46367216	0.975		COL6A2	collagen, type VI, alpha 2
chr9_+_132002692	0.974	NM_001128826	NCS1	neuronal calcium sensor 1
chr19_-_14748623	0.973		EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr1_-_240754620	0.959	NM_152666	PLD5	phospholipase D family, member 5
chr15_-_73792234	0.957	NM_001897	CSPG4	chondroitin sulfate proteoglycan 4
chr17_-_34607257	0.957	NM_000723 NM_199247 NM_199248	CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr14_-_91372365	0.957	NM_001128595 NM_152332	TC2N	tandem C2 domains, nuclear
chr1_-_151780720	0.948	NM_002962	S100A5	S100 calcium binding protein A5
chr11_-_57173823	0.941	NM_145008	YPEL4	yippee-like 4 (Drosophila)
chr5_+_78944151	0.940		PAPD4	PAP associated domain containing 4
chr7_+_44110470	0.938	NM_001129	AEBP1	AE binding protein 1
chrX_-_137621492	0.926	NM_004114	FGF13	fibroblast growth factor 13
chr11_+_65311104	0.924	NM_004561	OVOL1	ovo-like 1(Drosophila)
chr10_+_135343649	0.916	NM_012147	DUX2	double homeobox 2
chr19_+_13111072	0.914		NACC1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr12_+_1608672	0.910	NM_032642	WNT5B	wingless-type MMTV integration site family, member 5B
chr2_-_219882302	0.910	NM_002846	PTPRN	protein tyrosine phosphatase, receptor type, N
chr18_+_42168180	0.910	NM_152470	C18orf23 RNF165	chromosome 18 open reading frame 23 ring finger protein 165
chr6_-_10527772	0.908	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_69998064	0.906	NM_198177	MITF	microphthalmia-associated transcription factor
chr17_-_77474597	0.895	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr12_+_52634950	0.891	NM_173860	HOXC12	homeobox C12
chr3_-_13089547	0.884	NM_001134382	IQSEC1	IQ motif and Sec7 domain 1
chr19_+_3317536	0.883	NM_005597	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr8_+_41804946	0.876
chr12_+_52689062	0.872	NM_022658	HOXC8	homeobox C8
chr5_+_169863601	0.867	NM_001034837 NM_014592	KCNIP1	Kv channel interacting protein 1
chrX_-_1532648	0.866	NM_001173473	ASMTL	acetylserotonin O-methyltransferase-like
chr6_-_139654807	0.859	NM_153235	TXLNB	taxilin beta
chr16_+_665680	0.857		RHBDL1	rhomboid, veinlet-like 1 (Drosophila)
chr5_+_78944052	0.857		PAPD4	PAP associated domain containing 4
chr7_+_128219307	0.857	NM_022742	CCDC136	coiled-coil domain containing 136
chr15_+_72209973	0.856		ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chrX_-_153500584	0.855	NM_001327 NM_139250	CTAG1B CTAG1A	cancer/testis antigen 1B cancer/testis antigen 1A
chr13_+_113574925	0.855	NM_001143945	GAS6	growth arrest-specific 6
chr9_-_129729518	0.853	NM_173492	PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase-like 1
chr16_+_670115	0.852	NM_005861	STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr19_-_50977592	0.851	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr3_+_8750485	0.851	NM_033337 NM_001234	CAV3	caveolin 3
chr12_-_46438447	0.851	NM_001098532 NM_006105	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr2_+_238432925	0.848	NM_005855	RAMP1	receptor (G protein-coupled) activity modifying protein 1
chr9_-_139068269	0.846	NM_001246 NM_203468	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr7_+_44110527	0.846		AEBP1	AE binding protein 1
chr11_-_74740298	0.843	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr12_-_131816604	0.841		ANKLE2	ankyrin repeat and LEM domain containing 2
chr5_+_172193826	0.840	NM_001031711	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr2_-_74455161	0.834	NM_001135041 NM_023019	DCTN1	dynactin 1
chr6_-_48144344	0.834	NM_001013732 NM_207499	C6orf138	chromosome 6 open reading frame 138
chr19_+_4442610	0.830		HDGFRP2	hepatoma-derived growth factor-related protein 2
chr12_-_51887318	0.829		ITGB7	integrin, beta 7
chr17_-_19231049	0.828	NM_001198695 NM_002404	MFAP4	microfibrillar-associated protein 4
chr8_-_145122884	0.828	NM_000445	PLEC	plectin
chr6_-_6265896	0.824	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr22_-_42589543	0.822	NM_014351	SULT4A1	sulfotransferase family 4A, member 1
chr1_-_6162669	0.818	NM_015557	CHD5	chromodomain helicase DNA binding protein 5
chr16_+_750765	0.816	NM_005823 NM_001177355	MSLN	mesothelin
chr4_-_2336328	0.816	NM_001172659 NM_001172660	ZFYVE28	zinc finger, FYVE domain containing 28
chr7_-_150305933	0.814	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr16_-_3246587	0.814	NM_000243 NM_001198536	MEFV	Mediterranean fever
chr5_+_140871107	0.814
chr7_+_149657810	0.814	NM_138434	C7orf29	chromosome 7 open reading frame 29
chr8_-_145725289	0.813		C8orf82	chromosome 8 open reading frame 82
chr6_-_33822659	0.810	NM_001142883 NM_054111	IP6K3	inositol hexakisphosphate kinase 3
chr21_-_43369492	0.808	NM_001178008 NM_001178009	CBS	cystathionine-beta-synthase
chr3_-_130323295	0.803	NM_198490	RAB43	RAB43, member RAS oncogene family
chr1_-_2447848	0.802	NM_018216	PANK4	pantothenate kinase 4
chr1_-_148155986	0.799	NM_014849	SV2A	synaptic vesicle glycoprotein 2A
chr1_+_110012166	0.798	NM_000848 NM_001142368	GSTM2	glutathione S-transferase mu 2 (muscle)
chr20_-_21326046	0.796	NM_033176	NKX2-4	NK2 homeobox 4
chr16_+_620932	0.795	NM_053284	WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr11_+_122936246	0.794		GRAMD1B	GRAM domain containing 1B
chr4_-_1097313	0.794	NM_001131034 NM_001193318 NM_194439	RNF212	ring finger protein 212
chr11_-_17454995	0.792	NM_000352	ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr4_-_46086528	0.791	NM_000807	GABRA2	gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr5_-_180163495	0.788	NM_001114619 NM_001114620	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr2_-_227737009	0.788		COL4A4	collagen, type IV, alpha 4
chr5_+_180583315	0.788		TRIM41	tripartite motif containing 41
chr5_-_138746917	0.786	NM_005847 NM_152685	SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr16_-_1215254	0.786	NM_012467	TPSG1	tryptase gamma 1
chr20_-_56523251	0.775	NM_153360	APCDD1L	adenomatosis polyposis coli down-regulated 1-like
chr21_+_43985728	0.773		PDXK	pyridoxal (pyridoxine, vitamin B6) kinase
chr15_-_73792150	0.769		CSPG4	chondroitin sulfate proteoglycan 4
chr12_-_56157898	0.767	NM_001080156	ARHGAP9	Rho GTPase activating protein 9
chr11_-_1725662	0.767		LOC402778	CD225 family protein FLJ76511
chr10_-_103525646	0.766	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr11_-_128280801	0.766	NM_145013	C11orf45	chromosome 11 open reading frame 45
chr11_-_69228286	0.762	NM_005117	FGF19	fibroblast growth factor 19
chr18_+_55038369	0.762	NM_001012512 NM_001012513 NM_002091	GRP	gastrin-releasing peptide
chr22_+_49333327	0.759	NM_138433	KLHDC7B	kelch domain containing 7B
chr4_-_5941167	0.758	NM_001313	CRMP1	collapsin response mediator protein 1
chr7_+_73341640	0.757	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr11_+_66939720	0.755	NM_001166222 NM_020811	CARNS1	carnosine synthase 1
chr17_-_7434113	0.755	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chr10_-_64248932	0.754	NM_001136178	EGR2	early growth response 2
chr15_+_72209795	0.754	NM_020851	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr1_-_2115950	0.752	NM_182533	C1orf86	chromosome 1 open reading frame 86
chr19_-_13909877	0.747		PODNL1	podocan-like 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.56	3.09e-20	GO:0007399	nervous system development
1.35	9.46e-17	GO:0048731	system development
1.32	1.80e-16	GO:0048856	anatomical structure development
1.16	2.27e-16	GO:0065007	biological regulation
1.28	3.81e-16	GO:0032502	developmental process
1.30	1.15e-15	GO:0007275	multicellular organismal development
1.40	2.07e-13	GO:0048513	organ development
1.45	8.80e-13	GO:0009653	anatomical structure morphogenesis
1.15	1.65e-12	GO:0050789	regulation of biological process
1.60	2.80e-12	GO:0048699	generation of neurons
1.36	4.30e-12	GO:0030154	cell differentiation
1.16	6.07e-12	GO:0050794	regulation of cellular process
1.35	7.00e-12	GO:0048869	cellular developmental process
1.65	1.42e-11	GO:0030182	neuron differentiation
1.56	1.89e-11	GO:0022008	neurogenesis
1.68	8.45e-11	GO:0009887	organ morphogenesis
1.74	1.42e-10	GO:0007417	central nervous system development
1.62	3.09e-10	GO:0045595	regulation of cell differentiation
1.44	4.61e-10	GO:0051239	regulation of multicellular organismal process
1.52	9.03e-10	GO:0050793	regulation of developmental process
1.49	4.06e-09	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.49	9.31e-09	GO:0048468	cell development
1.36	1.41e-08	GO:0023051	regulation of signaling
1.29	2.13e-08	GO:0051252	regulation of RNA metabolic process
1.22	6.64e-08	GO:0080090	regulation of primary metabolic process
1.21	7.94e-08	GO:0023052	signaling
1.29	9.25e-08	GO:0048523	negative regulation of cellular process
1.77	1.16e-07	GO:0007420	brain development
1.82	1.17e-07	GO:0060284	regulation of cell development
1.25	1.24e-07	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.69	1.35e-07	GO:0007268	synaptic transmission
1.27	2.21e-07	GO:0048519	negative regulation of biological process
1.43	3.09e-07	GO:0007154	cell communication
1.51	3.82e-07	GO:2000026	regulation of multicellular organismal development
1.21	3.82e-07	GO:0031323	regulation of cellular metabolic process
1.28	4.18e-07	GO:0006355	regulation of transcription, DNA-dependent
1.24	4.74e-07	GO:0048518	positive regulation of biological process
1.50	5.03e-07	GO:0007267	cell-cell signaling
1.24	5.24e-07	GO:0051171	regulation of nitrogen compound metabolic process
2.28	5.46e-07	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.19	5.74e-07	GO:0019222	regulation of metabolic process
2.26	8.07e-07	GO:0022604	regulation of cell morphogenesis
1.69	1.25e-06	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.24	1.36e-06	GO:0031326	regulation of cellular biosynthetic process
1.30	1.48e-06	GO:0007166	cell surface receptor linked signaling pathway
1.40	1.60e-06	GO:0010646	regulation of cell communication
1.25	1.69e-06	GO:0048522	positive regulation of cellular process
1.61	2.04e-06	GO:0019226	transmission of nerve impulse
1.61	2.04e-06	GO:0035637	multicellular organismal signaling
2.04	2.16e-06	GO:0030900	forebrain development
1.24	2.36e-06	GO:0010468	regulation of gene expression
1.21	2.57e-06	GO:0060255	regulation of macromolecule metabolic process
1.23	3.61e-06	GO:0009889	regulation of biosynthetic process
1.50	4.20e-06	GO:0010628	positive regulation of gene expression
1.82	5.17e-06	GO:0045596	negative regulation of cell differentiation
1.15	6.10e-06	GO:0032501	multicellular organismal process
1.60	8.53e-06	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.51	9.05e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.78	1.07e-05	GO:0051960	regulation of nervous system development
1.55	1.19e-05	GO:0051253	negative regulation of RNA metabolic process
1.55	1.60e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.49	1.76e-05	GO:0051254	positive regulation of RNA metabolic process
1.24	1.76e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.92	2.05e-05	GO:0032582	negative regulation of gene-specific transcription
1.57	2.06e-05	GO:0000904	cell morphogenesis involved in differentiation
1.45	2.72e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.44	2.85e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.42	3.00e-05	GO:0009888	tissue development
2.02	3.05e-05	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.69	5.26e-05	GO:0051093	negative regulation of developmental process
1.55	6.08e-05	GO:0031175	neuron projection development
1.24	6.19e-05	GO:0065008	regulation of biological quality
1.22	8.03e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.58	8.67e-05	GO:0048667	cell morphogenesis involved in neuron differentiation
1.63	8.81e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.50	9.55e-05	GO:0048666	neuron development
1.69	1.12e-04	GO:0022603	regulation of anatomical structure morphogenesis
1.56	1.43e-04	GO:0048812	neuron projection morphogenesis
1.96	1.49e-04	GO:0006813	potassium ion transport
1.30	2.07e-04	GO:0009966	regulation of signal transduction
1.44	2.09e-04	GO:0009790	embryo development
1.46	2.19e-04	GO:0030030	cell projection organization
1.75	2.96e-04	GO:0050767	regulation of neurogenesis
1.18	3.15e-04	GO:0007165	signal transduction
1.39	3.68e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.38	3.83e-04	GO:0009891	positive regulation of biosynthetic process
1.56	4.08e-04	GO:0007409	axonogenesis
1.51	4.27e-04	GO:0048858	cell projection morphogenesis
1.66	5.40e-04	GO:0048729	tissue morphogenesis
1.46	5.43e-04	GO:0010629	negative regulation of gene expression
1.46	5.49e-04	GO:0000902	cell morphogenesis
1.41	5.88e-04	GO:0010557	positive regulation of macromolecule biosynthetic process
1.45	6.74e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.62	6.86e-04	GO:0044057	regulation of system process
1.80	7.13e-04	GO:0045664	regulation of neuron differentiation
1.50	7.54e-04	GO:0032990	cell part morphogenesis
1.45	7.87e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42	7.89e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.06	8.49e-04	GO:0009987	cellular process
1.24	9.69e-04	GO:0048583	regulation of response to stimulus
1.60	9.92e-04	GO:0007389	pattern specification process
1.44	1.08e-03	GO:0032989	cellular component morphogenesis
1.67	1.11e-03	GO:0061061	muscle structure development
1.92	1.14e-03	GO:0045165	cell fate commitment
1.57	1.29e-03	GO:0048598	embryonic morphogenesis
3.37	1.29e-03	GO:0071300	cellular response to retinoic acid
1.41	1.37e-03	GO:0009890	negative regulation of biosynthetic process
1.43	1.85e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.70	2.10e-03	GO:0048663	neuron fate commitment
1.42	2.11e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.64	2.34e-03	GO:0007423	sensory organ development
3.24	3.02e-03	GO:0071299	cellular response to vitamin A
1.50	3.36e-03	GO:0032583	regulation of gene-specific transcription
2.30	3.67e-03	GO:0050770	regulation of axonogenesis
1.82	4.45e-03	GO:0006936	muscle contraction
1.69	5.18e-03	GO:0002009	morphogenesis of an epithelium
1.92	6.54e-03	GO:0051969	regulation of transmission of nerve impulse
1.35	6.55e-03	GO:0051128	regulation of cellular component organization
1.56	6.71e-03	GO:0045597	positive regulation of cell differentiation
1.34	7.11e-03	GO:0006351	transcription, DNA-dependent
2.23	8.02e-03	GO:0010721	negative regulation of cell development
1.95	1.11e-02	GO:0050804	regulation of synaptic transmission
1.65	1.17e-02	GO:0003002	regionalization
1.90	1.46e-02	GO:0010975	regulation of neuron projection development
1.27	1.49e-02	GO:0009893	positive regulation of metabolic process
1.59	1.75e-02	GO:0035295	tube development
1.73	2.00e-02	GO:0003012	muscle system process
1.32	2.05e-02	GO:0031324	negative regulation of cellular metabolic process
1.30	2.11e-02	GO:0009605	response to external stimulus
1.43	2.26e-02	GO:0030001	metal ion transport
1.45	2.27e-02	GO:0051094	positive regulation of developmental process
1.27	2.73e-02	GO:0031325	positive regulation of cellular metabolic process
1.85	2.75e-02	GO:0042692	muscle cell differentiation
1.81	2.90e-02	GO:0031644	regulation of neurological system process
1.37	3.11e-02	GO:0007167	enzyme linked receptor protein signaling pathway
2.79	3.19e-02	GO:0071295	cellular response to vitamin
1.41	3.83e-02	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.77	4.98e-02	GO:0060562	epithelial tube morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	2.54e-07	GO:0044459	plasma membrane part
1.51	1.62e-06	GO:0030054	cell junction
1.61	2.95e-06	GO:0045202	synapse
1.66	4.61e-05	GO:0044456	synapse part
1.76	9.07e-05	GO:0034702	ion channel complex
1.95	1.51e-04	GO:0034703	cation channel complex
1.14	2.15e-04	GO:0005886	plasma membrane
1.14	5.10e-04	GO:0071944	cell periphery
1.51	1.10e-03	GO:0031012	extracellular matrix
1.54	1.95e-03	GO:0005578	proteinaceous extracellular matrix
2.05	2.95e-03	GO:0008076	voltage-gated potassium channel complex
2.05	2.95e-03	GO:0034705	potassium channel complex
1.48	3.91e-03	GO:0009986	cell surface
1.78	3.98e-03	GO:0045211	postsynaptic membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.83	9.38e-21	GO:0043565	sequence-specific DNA binding
1.55	1.60e-13	GO:0001071	nucleic acid binding transcription factor activity
1.55	1.60e-13	GO:0003700	sequence-specific DNA binding transcription factor activity
1.49	8.70e-11	GO:0030528	transcription regulator activity
1.12	4.05e-08	GO:0005515	protein binding
1.86	5.09e-08	GO:0005261	cation channel activity
1.65	6.84e-07	GO:0022838	substrate-specific channel activity
1.65	9.28e-07	GO:0005216	ion channel activity
2.10	1.77e-06	GO:0022843	voltage-gated cation channel activity
1.62	3.00e-06	GO:0015267	channel activity
1.61	3.57e-06	GO:0022803	passive transmembrane transporter activity
2.09	1.86e-05	GO:0005267	potassium channel activity
1.66	3.33e-05	GO:0022836	gated channel activity
1.86	3.66e-05	GO:0005244	voltage-gated ion channel activity
1.86	3.66e-05	GO:0022832	voltage-gated channel activity
1.82	4.29e-05	GO:0000975	regulatory region DNA binding
1.82	4.29e-05	GO:0001067	regulatory region nucleic acid binding
1.82	4.29e-05	GO:0044212	transcription regulatory region DNA binding
1.81	8.39e-05	GO:0010843	promoter binding
1.21	2.35e-04	GO:0003677	DNA binding
2.07	8.86e-04	GO:0005249	voltage-gated potassium channel activity
1.55	2.31e-03	GO:0016563	transcription activator activity
1.37	1.48e-02	GO:0008324	cation transmembrane transporter activity
1.05	1.92e-02	GO:0005488	binding
1.32	1.98e-02	GO:0015075	ion transmembrane transporter activity
1.49	3.30e-02	GO:0016564	transcription repressor activity