Motif ID: RREB1.p2

Z-value: 3.743


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_70529850.534.4e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_96924582 8.505 NM_001172667
FAM178B
family with sequence similarity 178, member B
chr1_-_30977931 6.778 LAPTM5
lysosomal protein transmembrane 5
chr14_+_104244998 5.104 INF2
inverted formin, FH2 and WH2 domain containing
chrX_+_17665483 3.635 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr4_-_809879 3.398 NM_006651
CPLX1
complexin 1
chr19_-_55914837 3.340


chr19_+_540849 2.851 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_-_1731273 2.788


chr10_-_135000464 2.600 NM_015722
CALY
calcyon neuron-specific vesicular protein
chr17_+_1580504 2.507 WDR81
WD repeat domain 81
chr10_-_135000358 2.398 CALY
calcyon neuron-specific vesicular protein
chr2_+_85515428 2.329 NM_198482
SH2D6
SH2 domain containing 6
chr17_+_39741306 2.260 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr10_-_75085754 2.208 NM_001114133
SYNPO2L
synaptopodin 2-like
chr19_-_13910167 2.189 NM_024825
PODNL1
podocan-like 1
chr19_-_16868674 2.165 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr3_-_48607596 2.134 NM_000094
COL7A1
collagen, type VII, alpha 1
chr20_-_61574259 2.118 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr1_-_202647526 2.100 NM_032833
PPP1R15B
protein phosphatase 1, regulatory (inhibitor) subunit 15B
chr6_-_31668476 2.062 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 138 entries
enrichment   p-value GO term description
3.37 1.29e-03 GO:0071300 cellular response to retinoic acid
3.24 3.02e-03 GO:0071299 cellular response to vitamin A
2.79 3.19e-02 GO:0071295 cellular response to vitamin
2.70 2.10e-03 GO:0048663 neuron fate commitment
2.30 3.67e-03 GO:0050770 regulation of axonogenesis
2.28 5.46e-07 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.26 8.07e-07 GO:0022604 regulation of cell morphogenesis
2.23 8.02e-03 GO:0010721 negative regulation of cell development
2.04 2.16e-06 GO:0030900 forebrain development
2.02 3.05e-05 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.96 1.49e-04 GO:0006813 potassium ion transport
1.95 1.11e-02 GO:0050804 regulation of synaptic transmission
1.92 2.05e-05 GO:0032582 negative regulation of gene-specific transcription
1.92 1.14e-03 GO:0045165 cell fate commitment
1.92 6.54e-03 GO:0051969 regulation of transmission of nerve impulse
1.90 1.46e-02 GO:0010975 regulation of neuron projection development
1.85 2.75e-02 GO:0042692 muscle cell differentiation
1.82 1.17e-07 GO:0060284 regulation of cell development
1.82 5.17e-06 GO:0045596 negative regulation of cell differentiation
1.82 4.45e-03 GO:0006936 muscle contraction

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.05 2.95e-03 GO:0008076 voltage-gated potassium channel complex
2.05 2.95e-03 GO:0034705 potassium channel complex
1.95 1.51e-04 GO:0034703 cation channel complex
1.78 3.98e-03 GO:0045211 postsynaptic membrane
1.76 9.07e-05 GO:0034702 ion channel complex
1.66 4.61e-05 GO:0044456 synapse part
1.61 2.95e-06 GO:0045202 synapse
1.54 1.95e-03 GO:0005578 proteinaceous extracellular matrix
1.51 1.62e-06 GO:0030054 cell junction
1.51 1.10e-03 GO:0031012 extracellular matrix
1.48 3.91e-03 GO:0009986 cell surface
1.26 2.54e-07 GO:0044459 plasma membrane part
1.14 2.15e-04 GO:0005886 plasma membrane
1.14 5.10e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.10 1.77e-06 GO:0022843 voltage-gated cation channel activity
2.09 1.86e-05 GO:0005267 potassium channel activity
2.07 8.86e-04 GO:0005249 voltage-gated potassium channel activity
1.86 5.09e-08 GO:0005261 cation channel activity
1.86 3.66e-05 GO:0005244 voltage-gated ion channel activity
1.86 3.66e-05 GO:0022832 voltage-gated channel activity
1.83 9.38e-21 GO:0043565 sequence-specific DNA binding
1.82 4.29e-05 GO:0000975 regulatory region DNA binding
1.82 4.29e-05 GO:0001067 regulatory region nucleic acid binding
1.82 4.29e-05 GO:0044212 transcription regulatory region DNA binding
1.81 8.39e-05 GO:0010843 promoter binding
1.66 3.33e-05 GO:0022836 gated channel activity
1.65 6.84e-07 GO:0022838 substrate-specific channel activity
1.65 9.28e-07 GO:0005216 ion channel activity
1.62 3.00e-06 GO:0015267 channel activity
1.61 3.57e-06 GO:0022803 passive transmembrane transporter activity
1.55 1.60e-13 GO:0001071 nucleic acid binding transcription factor activity
1.55 1.60e-13 GO:0003700 sequence-specific DNA binding transcription factor activity
1.55 2.31e-03 GO:0016563 transcription activator activity
1.49 8.70e-11 GO:0030528 transcription regulator activity