Motif ID: RXR{A,B,G}.p2

Z-value: 1.926


Transcription factors associated with RXR{A,B,G}.p2:

Gene SymbolEntrez IDGene Name
RXRA 6256 retinoid X receptor, alpha
RXRB 6257 retinoid X receptor, beta
RXRG 6258 retinoid X receptor, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RXRAchr9_+_1363581450.582.3e-02Click!
RXRGchr1_-_163680941-0.175.4e-01Click!
RXRBchr6_-_332764160.117.0e-01Click!


Activity profile for motif RXR{A,B,G}.p2.

activity profile for motif RXR{A,B,G}.p2


Sorted Z-values histogram for motif RXR{A,B,G}.p2

Sorted Z-values for motif RXR{A,B,G}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RXR{A,B,G}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_18081968 1.936 NM_002688
SEPT5
septin 5
chr12_+_52105131 1.279 AMHR2
anti-Mullerian hormone receptor, type II
chr22_+_18085891 1.158 SEPT5
septin 5
chr22_+_18085990 1.132 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr1_-_38285033 1.048 NM_002699
POU3F1
POU class 3 homeobox 1
chr12_+_56290229 0.975 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr11_-_62136778 0.955 NM_153265
EML3
echinoderm microtubule associated protein like 3
chr12_-_107775400 0.939 SSH1
slingshot homolog 1 (Drosophila)
chr17_+_78286687 0.906 NM_022158
FN3K
fructosamine 3 kinase
chr6_-_167289659 0.866


chr11_-_75595098 0.829 NM_004626
WNT11
wingless-type MMTV integration site family, member 11
chr21_-_32879617 0.829 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr19_-_54350457 0.819 NM_002152
HRC
histidine rich calcium binding protein
chr16_-_69277355 0.787 NM_138383
MTSS1L
metastasis suppressor 1-like
chr11_-_65187003 0.781 NM_001145138
NM_021975
RELA

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

chr19_-_17349096 0.779 NM_031310
PLVAP
plasmalemma vesicle associated protein
chr16_-_87244896 0.762 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr7_-_150283794 0.752 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_-_1840564 0.748 NM_178545
TMEM52
transmembrane protein 52
chr15_-_73818013 0.721


chr11_-_65186790 0.718 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr9_-_130006309 0.715 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr14_+_23937766 0.708 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr20_-_34925483 0.698 NM_080627
KIAA0889
KIAA0889
chr9_+_34643911 0.692 NM_004512
NM_147162
IL11RA

interleukin 11 receptor, alpha

chr9_-_139128777 0.692 DPP7
dipeptidyl-peptidase 7
chr4_+_134292630 0.692 PCDH10
protocadherin 10
chr20_-_43972949 0.689 PLTP
phospholipid transfer protein
chr22_+_48966394 0.683 TRABD
TraB domain containing
chr11_+_62136788 0.669 NM_000327
ROM1
retinal outer segment membrane protein 1
chr7_+_128219307 0.668 NM_022742
CCDC136
coiled-coil domain containing 136
chr8_+_145692916 0.651 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr17_+_76988134 0.650 NM_001080519
BAHCC1
BAH domain and coiled-coil containing 1
chr5_+_149845503 0.648 NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr16_+_620932 0.644 NM_053284
WFIKKN1
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr20_+_62158882 0.640 NM_198723
TCEA2
transcription elongation factor A (SII), 2
chr11_+_66643311 0.636 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr11_+_65162114 0.627 NM_006747
SIPA1
signal-induced proliferation-associated 1
chr2_+_113709553 0.625 LOC654433
hypothetical LOC654433
chr19_+_13066956 0.619 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_-_47468029 0.619 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr2_+_241586927 0.614 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr1_-_99242765 0.608 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr9_+_102275310 0.608 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr20_-_23014828 0.608 NM_012072
CD93
CD93 molecule
chr11_+_43920385 0.604 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr13_+_57105859 0.595 PCDH17
protocadherin 17
chr3_-_46710137 0.588 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr4_+_134293171 0.587 PCDH10
protocadherin 10
chr14_-_103058568 0.581 CKB
creatine kinase, brain
chr6_-_2916280 0.578 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr12_+_12829807 0.572 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr20_+_56659693 0.552 NM_001001433
NM_001134772
NM_001134773
NM_003763
STX16



syntaxin 16



chr15_-_38362078 0.552 NM_001190479
LOC100131244
hypothetical protein LOC100131244
chr18_-_44729700 0.550 NM_001190822
SMAD7
SMAD family member 7
chr9_+_35782405 0.550 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr3_+_161425946 0.549 NM_001168214
LOC401097
hypothetical protein LOC401097
chr19_+_4255590 0.549 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr19_+_18391423 0.547


chr1_-_92724181 0.546 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr20_+_48032918 0.541 NM_005985
SNAI1
snail homolog 1 (Drosophila)
chr5_+_80564894 0.536 NM_001099735
NM_001099736
NM_001825
CKMT2


creatine kinase, mitochondrial 2 (sarcomeric)


chr19_-_14089560 0.532 PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr19_+_18391211 0.532 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr17_+_40192072 0.531 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr22_+_21742364 0.526 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr16_-_86460529 0.520 NM_003486
SLC7A5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr3_-_124650081 0.519 NM_183357
ADCY5
adenylate cyclase 5
chr16_+_68765428 0.517 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr19_+_16860807 0.516 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr10_+_80569464 0.512 ZMIZ1
zinc finger, MIZ-type containing 1
chr17_+_7125702 0.510 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr4_-_2336328 0.501 NM_001172659
NM_001172660
ZFYVE28

zinc finger, FYVE domain containing 28

chr2_-_128155829 0.495 NM_001161404
LIMS2
LIM and senescent cell antigen-like domains 2
chr19_-_4509471 0.492 NM_032108
SEMA6B
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr22_+_48966480 0.487 NM_025204
TRABD
TraB domain containing
chr5_-_132141368 0.486 NM_001098813
SEPT8
septin 8
chr2_+_27155197 0.486 EMILIN1
elastin microfibril interfacer 1
chr20_-_61933012 0.482 ZBTB46
zinc finger and BTB domain containing 46
chr15_+_39008822 0.480 NM_019074
DLL4
delta-like 4 (Drosophila)
chr12_+_50587468 0.479 NM_000020
ACVRL1
activin A receptor type II-like 1
chr16_+_68542310 0.473 NM_182619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr4_+_658250 0.471 MYL5
myosin, light chain 5, regulatory
chr6_+_43846372 0.470 VEGFA
vascular endothelial growth factor A
chr11_+_817584 0.470 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr6_+_24602995 0.469 ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr6_+_108988797 0.466 FOXO3
forkhead box O3
chr19_-_15421761 0.465 NM_021241
WIZ
widely interspaced zinc finger motifs
chr11_-_63440891 0.462 NM_173587
RCOR2
REST corepressor 2
chr3_+_161426322 0.462 LOC401097
hypothetical protein LOC401097
chr7_+_100156358 0.450 NM_000799
EPO
erythropoietin
chr6_-_32247134 0.450 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr16_+_29734785 0.449 C16orf53
chromosome 16 open reading frame 53
chr19_-_55834895 0.445 NM_001160328
NM_001160329
SYT3

synaptotagmin III

chr3_-_38666122 0.443 NM_000335
NM_001099404
NM_001099405
NM_198056
NM_001160160
NM_001160161
SCN5A





sodium channel, voltage-gated, type V, alpha subunit





chr14_+_100270222 0.443 DLK1
delta-like 1 homolog (Drosophila)
chr17_-_42411587 0.441 NM_203400
RPRML
reprimo-like
chr11_-_69228286 0.438 NM_005117
FGF19
fibroblast growth factor 19
chr17_+_63799228 0.438 ARSG
arylsulfatase G
chr7_+_30927439 0.432 NM_001185060
NM_001185061
NM_001185062
AQP1


aquaporin 1 (Colton blood group)


chr19_-_15436333 0.427 NM_022904
RASAL3
RAS protein activator like 3
chr10_+_13182061 0.422 NM_001008211
NM_001008212
NM_001008213
NM_021980
OPTN



optineurin



chr2_-_219826854 0.422 NM_006000
TUBA4A
tubulin, alpha 4a
chr22_+_21742727 0.421 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr19_+_3310138 0.420 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr22_+_36632242 0.417 NM_033386
MICALL1
MICAL-like 1
chr16_+_2954217 0.417 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr3_-_50335113 0.417 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr17_-_70430839 0.415 NM_173477
USH1G
Usher syndrome 1G (autosomal recessive)
chr2_-_192767494 0.414 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr6_-_3172775 0.412 NM_178012
TUBB2B
tubulin, beta 2B
chr1_-_26245031 0.412 NM_001004434
NM_032513
SLC30A2

solute carrier family 30 (zinc transporter), member 2

chr14_+_76298693 0.412 VASH1
vasohibin 1
chr16_-_71650034 0.411 NM_001164766
ZFHX3
zinc finger homeobox 3
chr17_+_44643067 0.410 ABI3
ABI family, member 3
chr18_+_75261231 0.408 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr22_-_20235372 0.407 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr1_-_152185764 0.407 NM_014856
DENND4B
DENN/MADD domain containing 4B
chr8_+_145662510 0.407 NM_145754
KIFC2
kinesin family member C2
chr3_-_50315983 0.406 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr5_-_172687798 0.403 STC2
stanniocalcin 2
chr16_-_4795160 0.402 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr1_+_1233834 0.402 NM_153339
PUSL1
pseudouridylate synthase-like 1
chr17_-_39796649 0.402 NM_198475
FAM171A2
family with sequence similarity 171, member A2
chr17_+_71097147 0.396 MYO15B
myosin XVB pseudogene
chr1_-_36562341 0.394 NM_018166
FAM176B
family with sequence similarity 176, member B
chr20_-_43972982 0.393 PLTP
phospholipid transfer protein
chr16_-_87280289 0.389 SNAI3
snail homolog 3 (Drosophila)
chr22_-_45037882 0.389 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr10_+_88708267 0.388 NM_003087
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr1_-_154665807 0.385 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr9_-_109290528 0.384 KLF4
Kruppel-like factor 4 (gut)
chr11_-_124137260 0.383 NM_138961
ESAM
endothelial cell adhesion molecule
chr11_+_47543463 0.383 NM_001143984
NM_175732
PTPMT1

protein tyrosine phosphatase, mitochondrial 1

chr10_+_76256305 0.383 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr1_+_22251706 0.382 NM_001039802
NM_001791
NM_044472
CDC42


cell division cycle 42 (GTP binding protein, 25kDa)


chr10_-_30388439 0.378 NM_020848
KIAA1462
KIAA1462
chr19_+_40322231 0.375 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr17_-_76985538 0.373


chr9_-_139473433 0.369 NELF
nasal embryonic LHRH factor
chr19_-_972122 0.369 NM_001033026
NM_033420
C19orf6

chromosome 19 open reading frame 6

chr19_-_971995 0.365 C19orf6
chromosome 19 open reading frame 6
chr19_-_18409788 0.362 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr19_+_53589943 0.360 NM_000836
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr19_+_59064795 0.359 MYADM
myeloid-associated differentiation marker
chr19_-_7896974 0.359 NM_206833
CTXN1
cortexin 1
chr12_+_118515646 0.357 NM_001136534
TMEM233
transmembrane protein 233
chr16_+_29734990 0.356 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr1_-_41259973 0.356 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr3_+_38182251 0.354 OXSR1
oxidative-stress responsive 1
chr5_-_172688024 0.353 STC2
stanniocalcin 2
chr19_-_4674791 0.353 DPP9
dipeptidyl-peptidase 9
chr17_+_40581704 0.353 HEXIM1
hexamethylene bis-acetamide inducible 1
chr14_+_103165244 0.351 NM_001130107
NM_005552
NM_182923
KLC1


kinesin light chain 1


chr19_+_40824486 0.350 NM_014209
ETV2
ets variant 2
chr9_-_124030770 0.349 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr4_-_5879488 0.348 CRMP1
collapsin response mediator protein 1
chr5_+_131621276 0.347 PDLIM4
PDZ and LIM domain 4
chr20_+_60558369 0.347 C20orf166
chromosome 20 open reading frame 166
chr15_-_50869379 0.347 NM_004498
ONECUT1
one cut homeobox 1
chr16_+_65756084 0.347 HSF4
heat shock transcription factor 4
chr19_-_17236522 0.347 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr19_-_425875 0.346 NM_182577
ODF3L2
outer dense fiber of sperm tails 3-like 2
chr5_-_134762814 0.344 NM_001040158
NM_138609
NM_138610
H2AFY


H2A histone family, member Y


chr11_-_118740069 0.343 NM_171997
USP2
ubiquitin specific peptidase 2
chr7_-_72676750 0.343 NM_032951
NM_032952
NM_032953
NM_032954
MLXIPL



MLX interacting protein-like



chr22_-_19685998 0.341 THAP7
THAP domain containing 7
chr19_+_2240996 0.340


chr17_-_1478293 0.339 SLC43A2
solute carrier family 43, member 2
chr17_-_74361620 0.339 TIMP2
TIMP metallopeptidase inhibitor 2
chr6_-_2916786 0.339 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr19_+_44591589 0.338


chr22_+_20068039 0.338 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr22_-_42589543 0.338 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr13_+_48692472 0.337 NM_001507
MLNR
motilin receptor
chr17_+_40581617 0.337 HEXIM1
hexamethylene bis-acetamide inducible 1
chr11_-_65187121 0.336


chr6_-_85529031 0.336 TBX18
T-box 18
chr19_+_18584666 0.333 NM_012109
TMEM59L
transmembrane protein 59-like
chr5_+_170779264 0.332 NM_003862
FGF18
fibroblast growth factor 18
chr19_+_18312365 0.332 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr11_-_129377929 0.332 NM_020228
NM_199437
PRDM10

PR domain containing 10

chr7_+_100025131 0.332 NM_001163499
NM_012172
FBXO24

F-box protein 24

chr19_-_5291700 0.329 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr19_+_16860871 0.329 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr17_-_63798851 0.329 NM_001174166
NM_004694
SLC16A6

solute carrier family 16, member 6 (monocarboxylic acid transporter 7)

chr7_+_29486010 0.328 NM_001039936
CHN2
chimerin (chimaerin) 2
chrX_+_117513899 0.328 NM_144658
DOCK11
dedicator of cytokinesis 11
chr7_+_115953582 0.326 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr16_+_162845 0.325 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr6_-_32265489 0.322 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr19_+_18543613 0.322 NM_001033930
NM_003333
UBA52

ubiquitin A-52 residue ribosomal protein fusion product 1

chr3_+_49566901 0.322 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr11_-_900834 0.320 NM_001142674
NM_001142676
NM_001142677
NM_023947
CHID1



chitinase domain containing 1



chr19_+_34995290 0.320 NM_057182
CCNE1
cyclin E1
chr3_-_137397344 0.319 NM_018133
MSL2
male-specific lethal 2 homolog (Drosophila)
chr2_+_176724358 0.319 NM_014621
HOXD4
homeobox D4
chr19_-_4674814 0.312 NM_139159
DPP9
dipeptidyl-peptidase 9
chr14_-_104706159 0.312 NM_002226
NM_145159
JAG2

jagged 2

chr22_+_17539198 0.311



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.15 7.47e-07 GO:0065007 biological regulation
1.32 4.07e-06 GO:0048522 positive regulation of cellular process
1.30 7.59e-06 GO:0048518 positive regulation of biological process
1.09 9.40e-06 GO:0009987 cellular process
1.15 1.25e-05 GO:0050794 regulation of cellular process
1.25 1.83e-05 GO:0060255 regulation of macromolecule metabolic process
1.40 3.79e-05 GO:0009653 anatomical structure morphogenesis
1.14 5.75e-05 GO:0050789 regulation of biological process
1.23 8.25e-05 GO:0031323 regulation of cellular metabolic process
1.23 1.02e-04 GO:0080090 regulation of primary metabolic process
1.63 1.70e-04 GO:0010629 negative regulation of gene expression
1.36 1.78e-04 GO:0023051 regulation of signaling
1.28 2.24e-04 GO:0010468 regulation of gene expression
1.29 2.26e-04 GO:0048519 negative regulation of biological process
1.47 3.42e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.24 3.61e-04 GO:0048856 anatomical structure development
1.28 3.70e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.38 3.86e-04 GO:0009966 regulation of signal transduction
1.29 4.59e-04 GO:0051252 regulation of RNA metabolic process
1.29 6.86e-04 GO:0048523 negative regulation of cellular process
1.56 7.64e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.21 8.86e-04 GO:0032502 developmental process
1.58 1.04e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.25 1.08e-03 GO:0031326 regulation of cellular biosynthetic process
1.24 1.16e-03 GO:0048731 system development
1.20 1.17e-03 GO:0019222 regulation of metabolic process
1.26 1.20e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.22 1.21e-03 GO:0016043 cellular component organization
1.56 1.25e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.61 1.36e-03 GO:0051253 negative regulation of RNA metabolic process
1.53 1.44e-03 GO:0009890 negative regulation of biosynthetic process
1.25 1.45e-03 GO:0009889 regulation of biosynthetic process
1.25 1.49e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.61 1.65e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.57 2.05e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 2.29e-03 GO:0009892 negative regulation of metabolic process
1.45 2.77e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.21 2.98e-03 GO:0007275 multicellular organismal development
1.55 3.95e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.23 4.49e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.75 4.92e-03 GO:0032535 regulation of cellular component size
1.38 5.66e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.26 6.33e-03 GO:0006355 regulation of transcription, DNA-dependent
1.20 7.04e-03 GO:0071840 cellular component organization or biogenesis
1.29 7.24e-03 GO:0048583 regulation of response to stimulus
1.94 1.01e-02 GO:0044087 regulation of cellular component biogenesis
1.36 1.18e-02 GO:0031325 positive regulation of cellular metabolic process
1.42 1.36e-02 GO:0031324 negative regulation of cellular metabolic process
1.32 1.49e-02 GO:0007399 nervous system development
1.35 1.52e-02 GO:0009893 positive regulation of metabolic process
1.26 1.69e-02 GO:0030154 cell differentiation
2.18 2.27e-02 GO:0043254 regulation of protein complex assembly
1.58 2.33e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.48 2.45e-02 GO:0010628 positive regulation of gene expression
1.45 2.54e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.25 2.81e-02 GO:0048869 cellular developmental process
1.22 3.26e-02 GO:0071842 cellular component organization at cellular level
1.68 3.86e-02 GO:0071495 cellular response to endogenous stimulus
1.68 4.23e-02 GO:0033043 regulation of organelle organization
1.63 4.30e-02 GO:0090066 regulation of anatomical structure size
1.37 4.83e-02 GO:0032268 regulation of cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 2.30e-05 GO:0044424 intracellular part
1.08 6.29e-05 GO:0005622 intracellular
1.11 8.23e-05 GO:0005737 cytoplasm
1.09 5.94e-03 GO:0043231 intracellular membrane-bounded organelle
1.09 6.18e-03 GO:0043227 membrane-bounded organelle
1.08 7.49e-03 GO:0043226 organelle
1.08 8.97e-03 GO:0043229 intracellular organelle
1.12 1.04e-02 GO:0044444 cytoplasmic part
1.67 1.51e-02 GO:0015629 actin cytoskeleton
1.56 2.08e-02 GO:0043005 neuron projection
1.23 2.19e-02 GO:0005829 cytosol
1.03 4.64e-02 GO:0044464 cell part
1.03 4.80e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.46 4.13e-05 GO:0030528 transcription regulator activity
1.13 8.07e-05 GO:0005515 protein binding
1.54 1.72e-04 GO:0043565 sequence-specific DNA binding
1.41 1.18e-03 GO:0001071 nucleic acid binding transcription factor activity
1.41 1.18e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.06 6.39e-03 GO:0005488 binding
1.23 6.53e-03 GO:0003677 DNA binding
1.68 7.19e-03 GO:0016563 transcription activator activity