Motif ID: SMAD1..7,9.p2

Z-value: 3.496


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMAD3chr15_+_65217412-0.611.6e-02Click!
SMAD5chr5_+_135496437-0.524.9e-02Click!
SMAD2chr18_-_43710917-0.468.7e-02Click!
SMAD9chr13_-_363923700.459.4e-02Click!
SMAD4chr18_+_46810481-0.411.3e-01Click!
SMAD7chr18_-_44730706-0.401.4e-01Click!
SMAD6chr15_+_647824680.253.7e-01Click!
SMAD1chr4_+_146622154-0.234.2e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_143864933 4.060 NM_003695
 LY6D
lymphocyte antigen 6 complex, locus D
chr9_+_139239464 3.902 NM_199001
 C9orf169
chromosome 9 open reading frame 169
chr1_-_26553168 3.746 NM_001039775
 AIM1L
absent in melanoma 1-like
chr16_+_65579988 3.522 NM_173815
 CES4A
carboxylesterase 4A
chr15_+_39918302 3.435 NM_001114633
 PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr6_-_30151526 3.420 NM_170769
NM_025236
 RNF39

ring finger protein 39

chr17_-_19560470 3.391 NM_001099646
NM_152908
 SLC47A2

solute carrier family 47, member 2

chr16_-_73830025 3.293 BCAR1
breast cancer anti-estrogen resistance 1
chr2_+_233112680 3.244 NM_005199
 CHRNG
cholinergic receptor, nicotinic, gamma
chr1_+_199426575 3.234 NM_001164586
 IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr7_+_54577512 3.176 NM_182546
 VSTM2A
V-set and transmembrane domain containing 2A
chr1_+_15145001 3.166 NM_001017999
 KAZN
kazrin, periplakin interacting protein
chr1_+_15935395 3.156 NM_207348
 SLC25A34
solute carrier family 25, member 34
chr15_-_64644758 3.082 NM_207338
 LCTL
lactase-like
chr1_+_26220852 3.027 NM_004455
 EXTL1
exostoses (multiple)-like 1
chr1_+_144439069 3.024 NM_002614
 PDZK1
PDZ domain containing 1
chr17_-_36719030 3.012 NM_001146182
 KRTAP16-1
keratin associated protein 16-1
chr19_-_56204615 2.913 NM_012315
 KLK9
kallikrein-related peptidase 9
chr21_-_44911250 2.911 NM_181684
 KRTAP12-2
keratin associated protein 12-2
chr19_-_53808505 2.851 NM_017708
 FAM83E
family with sequence similarity 83, member E

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 38 entries
enrichment   p-value GO term description
1.89 2.28e-02 GO:0072507 divalent inorganic cation homeostasis
1.88 4.00e-02 GO:0055074 calcium ion homeostasis
1.83 3.49e-04 GO:0044057 regulation of system process
1.77 4.35e-03 GO:0007610 behavior
1.70 2.95e-02 GO:0060284 regulation of cell development
1.60 2.04e-02 GO:0048812 neuron projection morphogenesis
1.58 1.23e-02 GO:0031175 neuron projection development
1.55 3.57e-03 GO:0009887 organ morphogenesis
1.53 3.60e-03 GO:0030030 cell projection organization
1.52 2.47e-03 GO:0030182 neuron differentiation
1.52 2.04e-02 GO:0048666 neuron development
1.50 1.58e-04 GO:0022008 neurogenesis
1.50 3.10e-04 GO:0048699 generation of neurons
1.45 5.50e-07 GO:0007399 nervous system development
1.45 1.50e-03 GO:0048468 cell development
1.43 1.25e-02 GO:0009888 tissue development
1.43 4.40e-02 GO:0007267 cell-cell signaling
1.40 2.82e-05 GO:0009653 anatomical structure morphogenesis
1.40 7.32e-03 GO:0007154 cell communication
1.40 9.83e-03 GO:0009605 response to external stimulus

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.78 2.28e-04 GO:0005578 proteinaceous extracellular matrix
1.73 1.17e-04 GO:0031012 extracellular matrix
1.69 5.91e-03 GO:0015629 actin cytoskeleton
1.53 3.21e-02 GO:0043005 neuron projection
1.45 1.40e-02 GO:0030054 cell junction
1.36 4.74e-03 GO:0044421 extracellular region part
1.30 1.86e-05 GO:0044459 plasma membrane part
1.30 2.35e-02 GO:0005887 integral to plasma membrane
1.29 3.70e-02 GO:0031226 intrinsic to plasma membrane
1.22 4.13e-02 GO:0005576 extracellular region
1.19 6.95e-05 GO:0005886 plasma membrane
1.19 6.97e-05 GO:0071944 cell periphery
1.13 3.19e-05 GO:0016020 membrane
1.11 9.75e-03 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
7.45 3.82e-02 GO:0050542 icosanoid binding
7.45 3.82e-02 GO:0050543 icosatetraenoic acid binding
2.19 6.37e-03 GO:0008201 heparin binding
2.11 1.16e-03 GO:0005539 glycosaminoglycan binding
2.05 1.67e-03 GO:0001871 pattern binding
2.05 1.67e-03 GO:0030247 polysaccharide binding
1.51 6.88e-03 GO:0008092 cytoskeletal protein binding