Motif ID: SMAD1..7,9.p2

Z-value: 3.496


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMAD3chr15_+_65217412-0.611.6e-02Click!
SMAD5chr5_+_135496437-0.524.9e-02Click!
SMAD2chr18_-_43710917-0.468.7e-02Click!
SMAD9chr13_-_363923700.459.4e-02Click!
SMAD4chr18_+_46810481-0.411.3e-01Click!
SMAD7chr18_-_44730706-0.401.4e-01Click!
SMAD6chr15_+_647824680.253.7e-01Click!
SMAD1chr4_+_146622154-0.234.2e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_143864933 4.060 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr9_+_139239464 3.902 NM_199001
C9orf169
chromosome 9 open reading frame 169
chr1_-_26553168 3.746 NM_001039775
AIM1L
absent in melanoma 1-like
chr16_+_65579988 3.522 NM_173815
CES4A
carboxylesterase 4A
chr15_+_39918302 3.435 NM_001114633
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr6_-_30151526 3.420 NM_170769
NM_025236
RNF39

ring finger protein 39

chr17_-_19560470 3.391 NM_001099646
NM_152908
SLC47A2

solute carrier family 47, member 2

chr16_-_73830025 3.293 BCAR1
breast cancer anti-estrogen resistance 1
chr2_+_233112680 3.244 NM_005199
CHRNG
cholinergic receptor, nicotinic, gamma
chr1_+_199426575 3.234 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr7_+_54577512 3.176 NM_182546
VSTM2A
V-set and transmembrane domain containing 2A
chr1_+_15145001 3.166 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr1_+_15935395 3.156 NM_207348
SLC25A34
solute carrier family 25, member 34
chr15_-_64644758 3.082 NM_207338
LCTL
lactase-like
chr1_+_26220852 3.027 NM_004455
EXTL1
exostoses (multiple)-like 1
chr1_+_144439069 3.024 NM_002614
PDZK1
PDZ domain containing 1
chr17_-_36719030 3.012 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr19_-_56204615 2.913 NM_012315
KLK9
kallikrein-related peptidase 9
chr21_-_44911250 2.911 NM_181684
KRTAP12-2
keratin associated protein 12-2
chr19_-_53808505 2.851 NM_017708
FAM83E
family with sequence similarity 83, member E
chr22_+_23221114 2.688 NM_016327
UPB1
ureidopropionase, beta
chr1_+_26220895 2.601 EXTL1
exostoses (multiple)-like 1
chr7_-_1562272 2.600 NM_001097620
TMEM184A
transmembrane protein 184A
chr15_-_81037554 2.578 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr2_+_102169864 2.559 NM_003854
IL1RL2
interleukin 1 receptor-like 2
chr15_-_40236061 2.548 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr3_+_50279993 2.500 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr1_+_36409277 2.390 MAP7D1
MAP7 domain containing 1
chr14_-_49543987 2.384 NM_001012706
C14orf182
chromosome 14 open reading frame 182
chr16_+_82959626 2.338 NM_014861
ATP2C2
ATPase, Ca++ transporting, type 2C, member 2
chr7_+_75977680 2.334 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr11_+_125781157 2.311 ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr21_+_44844924 2.271 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr3_+_11171213 2.236 NM_001098212
HRH1
histamine receptor H1
chr15_+_31390454 2.211 NM_001036
RYR3
ryanodine receptor 3
chr11_-_18769703 2.192 NM_001039970
NM_006906
NM_032781
PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr1_-_16217871 2.176 NM_014424
HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr19_-_50977586 2.165 DMPK
dystrophia myotonica-protein kinase
chr3_-_52463070 2.155 NM_003280
TNNC1
troponin C type 1 (slow)
chr15_+_75074483 2.116 NM_003978
PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_+_15964045 2.104 NM_001024216
FBLIM1
filamin binding LIM protein 1
chr9_+_35663852 2.070 NM_001216
CA9
carbonic anhydrase IX
chr17_-_17421050 2.066 PEMT
phosphatidylethanolamine N-methyltransferase
chr20_-_57948653 2.039 NM_006242
PPP1R3D
protein phosphatase 1, regulatory (inhibitor) subunit 3D
chr18_-_45630154 2.038 MYO5B
myosin VB
chr19_-_56164628 2.034 NM_002774
KLK6
kallikrein-related peptidase 6
chr19_-_56221681 2.024 NM_001136032
KLK11
kallikrein-related peptidase 11
chr9_-_90456824 2.012 NM_001100111
LOC286238
hypothetical protein LOC286238
chr16_-_3246587 1.966 NM_000243
NM_001198536
MEFV

Mediterranean fever

chr7_-_141293185 1.951 NM_013252
CLEC5A
C-type lectin domain family 5, member A
chr4_+_40032146 1.901 NM_017581
CHRNA9
cholinergic receptor, nicotinic, alpha 9
chr1_-_43523825 1.894 NM_182517
NM_001164829
C1orf210

chromosome 1 open reading frame 210

chr9_-_138772506 1.892 NM_178469
LCN8
lipocalin 8
chr17_-_36346240 1.887 KRT23
keratin 23 (histone deacetylase inducible)
chr7_+_72883128 1.877 NM_001305
CLDN4
claudin 4
chr17_+_7199178 1.866 NM_198154
TMEM95
transmembrane protein 95
chr9_-_138387903 1.854 CARD9
caspase recruitment domain family, member 9
chr8_-_6722848 1.852 NM_005218
DEFB1
defensin, beta 1
chr15_-_81744469 1.851 NM_001717
BNC1
basonuclin 1
chr9_+_139241838 1.833 NM_001190228
LOC643596
hypothetical LOC643596
chr22_+_29848923 1.822 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_+_154478574 1.809 NM_199173
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr11_+_93394025 1.805 NM_001098672
HEPHL1
hephaestin-like 1
chr20_-_62052922 1.804 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr16_-_772926 1.791 NM_001025190
MSLNL
mesothelin-like
chr11_+_1812115 1.783 NM_138567
SYT8
synaptotagmin VIII
chr17_+_72795567 1.772 NM_001113492
SEPT9
septin 9
chr8_+_22493928 1.758 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr19_-_54258935 1.712 NM_006179
NTF4
neurotrophin 4
chr21_+_44818033 1.709 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr10_-_102880892 1.700 NM_001085398
TLX1NB
TLX1 neighbor
chr2_-_218575922 1.653 TNS1
tensin 1
chr19_-_50977592 1.630 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr5_+_170779664 1.616 FGF18
fibroblast growth factor 18
chr19_-_17275083 1.603 NM_024527
ABHD8
abhydrolase domain containing 8
chr21_+_44881700 1.603 NM_181688
KRTAP10-10
keratin associated protein 10-10
chr3_+_89239363 1.595 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr9_-_138387926 1.593 NM_052813
NM_052814
CARD9

caspase recruitment domain family, member 9

chr1_+_20751518 1.590 NM_207334
FAM43B
family with sequence similarity 43, member B
chr17_-_19231049 1.588 NM_001198695
NM_002404
MFAP4

microfibrillar-associated protein 4

chr19_-_50977485 1.579 DMPK
dystrophia myotonica-protein kinase
chr20_-_35586366 1.561 NM_001167823
BLCAP
bladder cancer associated protein
chr8_-_144726064 1.560 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr16_+_2071631 1.548 TSC2
tuberous sclerosis 2
chr15_+_75074793 1.546 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr9_-_103289154 1.531 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr11_-_63014986 1.527 NM_001146728
NM_001146729
NM_054108
HRASLS5


HRAS-like suppressor family, member 5


chr17_+_39741306 1.515 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr12_+_6292077 1.509 NM_001144857
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr2_+_69055208 1.504 NM_019617
GKN1
gastrokine 1
chr5_+_131437383 1.487 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr19_+_40299058 1.472 FXYD3
FXYD domain containing ion transport regulator 3
chr9_-_139010805 1.461 NM_004669
CLIC3
chloride intracellular channel 3
chr16_-_73858179 1.460 NM_001170716
BCAR1
breast cancer anti-estrogen resistance 1
chr7_+_129807467 1.458 NM_001868
CPA1
carboxypeptidase A1 (pancreatic)
chr19_+_702108 1.452 NM_173481
C19orf21
chromosome 19 open reading frame 21
chr9_-_34652629 1.450 NM_006664
CCL27
chemokine (C-C motif) ligand 27
chr1_-_24342158 1.435 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr21_-_41479035 1.429 NM_182832
PLAC4
placenta-specific 4
chr1_+_111571803 1.416 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr6_+_47732181 1.410 NM_153839
GPR111
G protein-coupled receptor 111
chr8_+_106400322 1.408 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr3_+_89239494 1.406 EPHA3
EPH receptor A3
chr16_+_70117523 1.391 NM_005769
NM_001166395
CHST4

carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4

chr10_-_76538859 1.385 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr11_+_116580892 1.380 TAGLN
transgelin
chr11_-_1725662 1.375 LOC402778
CD225 family protein FLJ76511
chr3_+_112934016 1.366 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr8_+_63323739 1.347 NKAIN3
Na+/K+ transporting ATPase interacting 3
chr15_+_75074743 1.346 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr1_-_159325709 1.340 PVRL4
poliovirus receptor-related 4
chr16_+_56219802 1.337 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr16_-_56389176 1.329 NM_001130099
KIFC3
kinesin family member C3
chr17_-_35911340 1.311 NM_032865
TNS4
tensin 4
chr3_-_46693902 1.307 NM_182775
ALS2CL
ALS2 C-terminal like
chr21_-_44803049 1.303 NM_198696
KRTAP10-3
keratin associated protein 10-3
chr20_-_32363268 1.298 NM_001161766
AHCY
adenosylhomocysteinase
chr10_-_98021144 1.292 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_-_49732062 1.286 NM_198722
AMIGO3
adhesion molecule with Ig-like domain 3
chr19_-_53912025 1.281 NM_182574
MAMSTR
MEF2 activating motif and SAP domain containing transcriptional regulator
chr14_-_94053933 1.281 NM_173850
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chr12_+_55896844 1.280 NM_007224
NXPH4
neurexophilin 4
chr2_-_108972100 1.276 NM_022336
EDAR
ectodysplasin A receptor
chr22_+_18330049 1.275 NM_007310
COMT
catechol-O-methyltransferase
chr19_-_40711034 1.268 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr2_-_219633481 1.242 NM_002181
IHH
Indian hedgehog
chr3_-_197549588 1.241 TM4SF19
transmembrane 4 L six family member 19
chr17_-_59403932 1.221 NM_000334
SCN4A
sodium channel, voltage-gated, type IV, alpha subunit
chrX_+_152682772 1.218 NM_001163257
NM_005393
PLXNB3

plexin B3

chr13_-_26232777 1.215 NM_005288
GPR12
G protein-coupled receptor 12
chr7_-_76667045 1.209 NM_006682
FGL2
fibrinogen-like 2
chr7_-_150283794 1.204 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr10_+_102881050 1.197 NM_001195517
NM_005521
TLX1

T-cell leukemia homeobox 1

chr1_+_1256585 1.191 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr12_+_56406296 1.188 LOC100130776
hypothetical LOC100130776
chr1_-_201321999 1.187 NM_002479
MYOG
myogenin (myogenic factor 4)
chr22_+_40093245 1.187 NM_001145398
TEF
thyrotrophic embryonic factor
chr12_-_47651812 1.186 NM_003394
WNT10B
wingless-type MMTV integration site family, member 10B
chr3_-_129689394 1.185 NM_001145662
GATA2
GATA binding protein 2
chr1_+_232416618 1.183 SLC35F3
solute carrier family 35, member F3
chr2_+_135312655 1.182 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr11_-_110888273 1.178 NM_017589
BTG4
B-cell translocation gene 4
chr22_+_43451600 1.165 PRR5
proline rich 5 (renal)
chr13_+_28900776 1.160 NM_015233
MTUS2
microtubule associated tumor suppressor candidate 2
chr19_-_56163815 1.157 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr1_-_201321711 1.150 MYOG
myogenin (myogenic factor 4)
chr1_+_226404037 1.143 NM_020435
GJC2
gap junction protein, gamma 2, 47kDa
chr22_-_41372920 1.135 NM_001129819
NM_001171661
NM_007326
CYB5R3


cytochrome b5 reductase 3


chr19_-_60573552 1.126 NM_000641
IL11
interleukin 11
chr2_+_85515428 1.120 NM_198482
SH2D6
SH2 domain containing 6
chr16_-_29373785 1.116 NM_001031827
NM_001039182
BOLA2
BOLA2B
bolA homolog 2 (E. coli)
bolA homolog 2B (E. coli)
chr10_-_82106479 1.114 NM_138812
DYDC1
DPY30 domain containing 1
chr16_-_17472238 1.107 NM_022166
XYLT1
xylosyltransferase I
chr12_-_51200347 1.107 NM_000424
KRT5
keratin 5
chr11_-_70350292 1.102 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr12_+_52689062 1.086 NM_022658
HOXC8
homeobox C8
chr16_+_65436341 1.082 NM_001014435
CA7
carbonic anhydrase VII
chr2_+_71016503 1.081 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr14_+_66725862 1.081 NM_173526
FAM71D
family with sequence similarity 71, member D
chr1_-_41722883 1.075 NM_001956
EDN2
endothelin 2
chr2_-_108972048 1.067 EDAR
ectodysplasin A receptor
chr9_+_132002692 1.064 NM_001128826
NCS1
neuronal calcium sensor 1
chr5_+_179153591 1.064 NM_145867
LTC4S
leukotriene C4 synthase
chr7_+_147667461 1.062 CNTNAP2
contactin associated protein-like 2
chr11_+_47564805 1.058 NM_001164379
FAM180B
family with sequence similarity 180, member B
chr17_-_36877002 1.051 NM_002278
KRT32
keratin 32
chr11_-_60819110 1.049 VWCE
von Willebrand factor C and EGF domains
chr2_+_176761552 1.045 NM_024501
HOXD1
homeobox D1
chr7_+_1543644 1.041 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr22_-_18841785 1.038 NM_015672
RIMBP3
RIMS binding protein 3
chr7_-_102070473 1.036 NM_001114403
UPK3BL
POLR2J2
uroplakin 3B-like
polymerase (RNA) II (DNA directed) polypeptide J2
chr3_+_44601457 1.035 NM_173658
ZNF660
zinc finger protein 660
chr5_-_146813343 1.034 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr19_+_45973139 1.028 NM_006533
MIA
melanoma inhibitory activity
chr2_+_101981888 1.026 NM_173343
IL1R2
interleukin 1 receptor, type II
chr2_+_96818048 1.020 CNNM4
cyclin M4
chr3_-_62835601 1.020


chr7_+_133862883 1.020 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr22_-_41372620 1.016 CYB5R3
cytochrome b5 reductase 3
chr15_-_50869379 1.016 NM_004498
ONECUT1
one cut homeobox 1
chr4_-_8211335 1.010 NM_001130083
NM_001130084
NM_001130085
NM_001130086
NM_001130087
NM_001130088
NM_032432
ABLIM2






actin binding LIM protein family, member 2






chr10_+_22765996 1.009 LOC100289455
hypothetical LOC100289455
chr1_-_28392966 0.998 NM_001164722
NM_001164721
PTAFR

platelet-activating factor receptor

chr1_-_31618405 0.995 NM_004102
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr9_+_138991835 0.993 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr1_-_39180036 0.985 NM_017821
RHBDL2
rhomboid, veinlet-like 2 (Drosophila)
chr17_+_1574782 0.983 NM_001163809
WDR81
WD repeat domain 81
chr1_+_44171578 0.983 NM_001136215
NM_057090
NM_057091
ARTN


artemin


chr19_+_3659358 0.978 TJP3
tight junction protein 3 (zona occludens 3)
chr3_-_127382051 0.975 ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr12_-_52980914 0.973 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr17_+_68672705 0.964 NM_001050
SSTR2
somatostatin receptor 2
chr20_-_3635774 0.957 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr17_+_72958330 0.955 SEPT9
septin 9
chr17_+_71582486 0.954 NM_003857
GALR2
galanin receptor 2
chr8_-_57395207 0.954 SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr16_+_65018316 0.954 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr12_-_51153788 0.953 NM_173086
KRT6C
keratin 6C
chr3_-_127382093 0.951 NM_012190
ALDH1L1
aldehyde dehydrogenase 1 family, member L1
chr3_-_197549640 0.949 NM_138461
TM4SF19
transmembrane 4 L six family member 19

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.34 4.53e-09 GO:0048731 system development
1.30 5.20e-08 GO:0048856 anatomical structure development
1.28 1.98e-07 GO:0007275 multicellular organismal development
1.45 5.50e-07 GO:0007399 nervous system development
1.25 4.06e-06 GO:0023052 signaling
1.24 8.97e-06 GO:0032502 developmental process
1.40 2.82e-05 GO:0009653 anatomical structure morphogenesis
1.24 3.71e-05 GO:0007165 signal transduction
1.50 1.58e-04 GO:0022008 neurogenesis
1.50 3.10e-04 GO:0048699 generation of neurons
1.83 3.49e-04 GO:0044057 regulation of system process
1.30 4.51e-04 GO:0030154 cell differentiation
1.16 8.88e-04 GO:0032501 multicellular organismal process
1.38 9.61e-04 GO:0051239 regulation of multicellular organismal process
1.45 1.50e-03 GO:0048468 cell development
1.28 1.76e-03 GO:0048869 cellular developmental process
1.52 2.47e-03 GO:0030182 neuron differentiation
1.11 2.84e-03 GO:0065007 biological regulation
1.18 3.13e-03 GO:0051716 cellular response to stimulus
1.35 3.31e-03 GO:0035556 intracellular signal transduction
1.55 3.57e-03 GO:0009887 organ morphogenesis
1.53 3.60e-03 GO:0030030 cell projection organization
1.29 3.99e-03 GO:0048513 organ development
1.77 4.35e-03 GO:0007610 behavior
1.40 7.32e-03 GO:0007154 cell communication
1.40 9.83e-03 GO:0009605 response to external stimulus
1.58 1.23e-02 GO:0031175 neuron projection development
1.43 1.25e-02 GO:0009888 tissue development
1.60 2.04e-02 GO:0048812 neuron projection morphogenesis
1.52 2.04e-02 GO:0048666 neuron development
1.89 2.28e-02 GO:0072507 divalent inorganic cation homeostasis
1.70 2.95e-02 GO:0060284 regulation of cell development
1.11 3.05e-02 GO:0050789 regulation of biological process
1.11 3.57e-02 GO:0050794 regulation of cellular process
1.88 4.00e-02 GO:0055074 calcium ion homeostasis
1.43 4.40e-02 GO:0007267 cell-cell signaling
1.24 4.82e-02 GO:0065008 regulation of biological quality
1.27 4.98e-02 GO:0007166 cell surface receptor linked signaling pathway

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.86e-05 GO:0044459 plasma membrane part
1.13 3.19e-05 GO:0016020 membrane
1.19 6.95e-05 GO:0005886 plasma membrane
1.19 6.97e-05 GO:0071944 cell periphery
1.73 1.17e-04 GO:0031012 extracellular matrix
1.78 2.28e-04 GO:0005578 proteinaceous extracellular matrix
1.36 4.74e-03 GO:0044421 extracellular region part
1.69 5.91e-03 GO:0015629 actin cytoskeleton
1.11 9.75e-03 GO:0044425 membrane part
1.45 1.40e-02 GO:0030054 cell junction
1.30 2.35e-02 GO:0005887 integral to plasma membrane
1.53 3.21e-02 GO:0043005 neuron projection
1.29 3.70e-02 GO:0031226 intrinsic to plasma membrane
1.22 4.13e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.11 1.16e-03 GO:0005539 glycosaminoglycan binding
2.05 1.67e-03 GO:0001871 pattern binding
2.05 1.67e-03 GO:0030247 polysaccharide binding
2.19 6.37e-03 GO:0008201 heparin binding
1.51 6.88e-03 GO:0008092 cytoskeletal protein binding
7.45 3.82e-02 GO:0050542 icosanoid binding
7.45 3.82e-02 GO:0050543 icosatetraenoic acid binding