Motif ID: SOX17.p2

Z-value: 0.837


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX17chr8_+_55533047-0.731.9e-03Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_24600661 0.885 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr11_-_16380967 0.837 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr7_+_128802719 0.709 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr19_+_11510578 0.695 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr19_+_63482118 0.680 NM_021089
ZNF8
zinc finger protein 8
chr17_-_69869552 0.669 NM_001080466
BTBD17
BTB (POZ) domain containing 17
chr16_-_45339605 0.656 NM_182493
MYLK3
myosin light chain kinase 3
chr2_+_232281491 0.622 PTMA
prothymosin, alpha
chr1_-_166149867 0.578 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr5_+_180726874 0.575 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr2_+_232281470 0.571 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr1_+_207668787 0.545 NM_001104548
LOC642587
NPC-A-5
chr8_-_107023 0.540 NM_001005504
OR4F21
olfactory receptor, family 4, subfamily F, member 21
chr19_-_56582997 0.526 NM_001161748
NM_030657
LIM2

lens intrinsic membrane protein 2, 19kDa

chr15_-_100280784 0.524 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr2_-_37752272 0.506 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr2_-_157890400 0.503 NM_020711
ERMN
ermin, ERM-like protein
chr19_-_54350457 0.502 NM_002152
HRC
histidine rich calcium binding protein
chr11_-_550706 0.496 NM_173573
C11orf35
chromosome 11 open reading frame 35
chr22_+_20316968 0.493 NM_152612
CCDC116
coiled-coil domain containing 116
chr6_+_25862905 0.465 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr1_-_51560469 0.463 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr7_-_111633428 0.457 DOCK4
dedicator of cytokinesis 4
chr17_-_59817722 0.439 NM_000442
PECAM1
platelet/endothelial cell adhesion molecule
chr17_-_59817654 0.424 PECAM1
platelet/endothelial cell adhesion molecule
chr13_-_107317460 0.416 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr17_-_59817575 0.397 PECAM1
platelet/endothelial cell adhesion molecule
chr1_+_58899 0.392 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr19_+_47040863 0.392 NM_001040283
DMRTC2
DMRT-like family C2
chr11_-_6418705 0.389 NM_000613
HPX
hemopexin
chr17_-_77092569 0.389 ACTG1
actin, gamma 1
chr1_-_59022275 0.386 NM_002228
JUN
jun proto-oncogene
chr6_+_114285209 0.386 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr16_-_79811475 0.377 NM_001076780
NM_052892
PKD1L2

polycystic kidney disease 1-like 2

chr1_-_611896 0.373 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr16_-_11282595 0.371 NM_002761
PRM1
protamine 1
chr1_+_165564904 0.369 NM_001198783
POU2F1
POU class 2 homeobox 1
chr8_-_145713959 0.368 NM_004260
RECQL4
RecQ protein-like 4
chr16_-_28425632 0.367 NM_145659
IL27
interleukin 27
chr3_-_187309442 0.367 NM_004454
ETV5
ets variant 5
chr9_+_136358145 0.365 RXRA
retinoid X receptor, alpha
chr14_-_99842519 0.362 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr9_-_130980302 0.361 IER5L
immediate early response 5-like
chr12_-_61283474 0.359 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr1_+_170017430 0.358 METTL13
methyltransferase like 13
chr1_+_357502 0.357 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr9_-_130980359 0.351 NM_203434
IER5L
immediate early response 5-like
chr19_-_12807221 0.351 NM_031429
RTBDN
retbindin
chr19_+_61624 0.350 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr7_-_44547382 0.347 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr12_-_23995220 0.343 SOX5
SRY (sex determining region Y)-box 5
chr16_-_78192111 0.341 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr9_+_134843918 0.341 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr1_+_170017452 0.340 METTL13
methyltransferase like 13
chr6_+_20510019 0.339 NM_001949
E2F3
E2F transcription factor 3
chr9_-_138778780 0.337 NM_203347
LCN15
lipocalin 15
chr1_+_165565006 0.334 POU2F1
POU class 2 homeobox 1
chr14_-_22974707 0.334 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr6_+_33047952 0.333 BRD2
bromodomain containing 2
chr5_+_139761656 0.326 ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr16_-_2201011 0.324 NM_182563
C16orf79
chromosome 16 open reading frame 79
chr5_+_76047536 0.324 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr5_+_148766632 0.322 LOC728264
hypothetical LOC728264
chr17_-_59817456 0.320 PECAM1
platelet/endothelial cell adhesion molecule
chr17_-_77092831 0.318 ACTG1
actin, gamma 1
chr4_-_185963859 0.315 ACSL1
acyl-CoA synthetase long-chain family member 1
chr11_-_64368616 0.313 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr1_+_149299490 0.311 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr10_-_75080784 0.311 NM_024875
SYNPO2L
synaptopodin 2-like
chr22_-_25344037 0.309 CRYBB1
crystallin, beta B1
chr9_+_136358134 0.309 NM_002957
RXRA
retinoid X receptor, alpha
chr19_+_50137334 0.304 NM_001646
APOC4-APOC2
APOC4
APOC4-APOC2 read-through transcript
apolipoprotein C-IV
chr17_-_36347197 0.303 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr5_+_139761579 0.301 NM_020690
NM_001197030
NM_017747
NM_017978
NM_024668
ANKHD1-EIF4EBP3
ANKHD1



ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1



chr1_-_202730135 0.293 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr14_-_23623657 0.293 NM_006177
NRL
neural retina leucine zipper
chr5_+_132037271 0.293 NM_000589
NM_172348
IL4

interleukin 4

chr5_+_139761608 0.293 ANKHD1
ankyrin repeat and KH domain containing 1
chr11_-_60880799 0.288 NM_001161452
CYBASC3
cytochrome b, ascorbate dependent 3
chr9_+_132990760 0.283 NM_005085
NUP214
nucleoporin 214kDa
chr1_-_219982016 0.282 DUSP10
dual specificity phosphatase 10
chrX_+_70359780 0.281 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr1_+_158603480 0.281 NM_005598
NHLH1
nescient helix loop helix 1
chr9_+_138810610 0.280 NM_001039374
KIAA1984
KIAA1984
chr17_+_72883759 0.279 NM_001113494
SEPT9
septin 9
chr12_-_23995109 0.279 SOX5
SRY (sex determining region Y)-box 5
chr9_-_132759045 0.279 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr2_+_74914742 0.279 HK2
hexokinase 2
chr6_+_30797393 0.278 TUBB
tubulin, beta
chr19_-_6230927 0.276 NM_005934
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr5_+_102493155 0.274 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr6_-_91063181 0.273 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr2_+_12775814 0.269


chr9_+_132990834 0.268 NUP214
nucleoporin 214kDa
chr11_+_61943082 0.268 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr19_+_56990222 0.268 NM_002030
FPR3
formyl peptide receptor 3
chr22_+_22703107 0.267 NM_001144931
LOC391322
D-dopachrome tautomerase-like
chr9_-_98220360 0.267 ZNF367
zinc finger protein 367
chr12_+_52680143 0.265 NM_006897
HOXC9
homeobox C9
chr17_-_77093603 0.263 ACTG1
actin, gamma 1
chr4_-_40211324 0.263 RBM47
RNA binding motif protein 47
chr22_-_25343959 0.262 NM_001887
CRYBB1
crystallin, beta B1
chr1_+_183281173 0.260 NM_007212
RNF2
ring finger protein 2
chr11_-_57173823 0.260 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr12_+_62524778 0.260 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr1_-_219982049 0.260 DUSP10
dual specificity phosphatase 10
chr1_+_54880014 0.258 NM_001039464
HEATR8-TTC4
HEATR8
HEATR8-TTC4 read-through transcript
HEAT repeat containing 8
chr1_+_149299504 0.258 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr11_+_4564596 0.257 NM_001005170
OR52I2
olfactory receptor, family 52, subfamily I, member 2
chr1_+_110683586 0.257 RBM15
RNA binding motif protein 15
chr9_+_102275310 0.255 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_50596238 0.255 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr8_+_26491507 0.255 DPYSL2
dihydropyrimidinase-like 2
chr10_+_70418482 0.254 NM_015634
KIAA1279
KIAA1279
chr1_+_179164195 0.254


chr10_+_114033403 0.251 NM_058222
TECTB
tectorin beta
chr11_-_6773589 0.251 NM_003696
OR6A2
olfactory receptor, family 6, subfamily A, member 2
chr2_+_178893216 0.251 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr2_+_73864823 0.250 NM_001080474
C2orf78
chromosome 2 open reading frame 78
chr1_-_16033866 0.249


chr10_-_97311084 0.248 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr21_-_36870736 0.247 NM_001146077
CLDN14
claudin 14
chr17_-_77093468 0.244 ACTG1
actin, gamma 1
chr5_+_139761634 0.243 ANKHD1-EIF4EBP3
ANKHD1
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr17_-_70690688 0.241 NM_001005849
NM_006937
SUMO2

SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)

chr6_+_50789215 0.241 NM_172238
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr1_+_6767968 0.239 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr15_-_38188333 0.239 NM_001003940
BMF
Bcl2 modifying factor
chr9_-_129752687 0.239 NM_203305
FAM102A
family with sequence similarity 102, member A
chr17_+_43374021 0.237 PNPO
pyridoxamine 5'-phosphate oxidase
chr1_-_143708467 0.237 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr19_+_60580015 0.235 NM_139172
TMEM190
transmembrane protein 190
chr6_+_37511383 0.234


chr7_+_73341640 0.233 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr1_-_112083387 0.233 NM_019099
C1orf183
chromosome 1 open reading frame 183
chr17_+_42641426 0.233 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr1_-_232810443 0.232


chr17_-_45280377 0.231 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr9_-_125070675 0.231 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr4_-_80466177 0.229 NM_032693
NAA11
N(alpha)-acetyltransferase 11, NatA catalytic subunit
chr16_-_57221240 0.229 NM_016284
NM_206999
CNOT1

CCR4-NOT transcription complex, subunit 1

chr20_+_41519947 0.229 SRSF6
serine/arginine-rich splicing factor 6
chr20_+_57027703 0.227 NM_030773
TUBB1
tubulin, beta 1
chr14_+_38714111 0.225 NM_002687
PNN
pinin, desmosome associated protein
chr16_-_57221235 0.225 CNOT1
CCR4-NOT transcription complex, subunit 1
chr5_-_95323180 0.225 ELL2
elongation factor, RNA polymerase II, 2
chr6_-_66473790 0.224 NM_001142800
NM_001142801
EYS

eyes shut homolog (Drosophila)

chr3_+_9748769 0.224 BRPF1
bromodomain and PHD finger containing, 1
chr19_-_53832381 0.222 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr7_-_111633620 0.222 NM_014705
DOCK4
dedicator of cytokinesis 4
chr15_+_82945223 0.221 NM_001007072
NM_017894
NM_181877
ZSCAN2


zinc finger and SCAN domain containing 2


chr7_+_156128431 0.221 NM_001184997
RNF32
ring finger protein 32
chr6_-_30763057 0.221 NM_001134870
KIAA1949
KIAA1949
chr16_-_57221228 0.221 CNOT1
CCR4-NOT transcription complex, subunit 1
chr1_+_158636987 0.221 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr9_+_94766379 0.220 FGD3
FYVE, RhoGEF and PH domain containing 3
chr17_-_37590910 0.220 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr11_-_66482366 0.220 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr3_-_47180417 0.219 NM_014159
SETD2
SET domain containing 2
chr21_+_40161216 0.219 NM_006198
PCP4
Purkinje cell protein 4
chr17_-_34607257 0.218 NM_000723
NM_199247
NM_199248
CACNB1


calcium channel, voltage-dependent, beta 1 subunit


chr6_+_30212488 0.218 NM_138700
TRIM40
tripartite motif containing 40
chrX_+_70360184 0.217 GJB1
gap junction protein, beta 1, 32kDa
chr9_-_98220482 0.217 NM_153695
ZNF367
zinc finger protein 367
chr10_+_31650069 0.215 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr19_+_62434188 0.215 NM_001015879
NM_003160
NM_001015878
AURKC


aurora kinase C


chr2_+_169631777 0.214 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr11_-_66898223 0.212 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr5_-_179040580 0.212 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr17_-_70690664 0.212 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr2_-_71307705 0.211 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr20_+_60130963 0.210 LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr12_-_46499834 0.210 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr7_+_26158257 0.209 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr9_+_129951552 0.209 NM_005564
LCN2
lipocalin 2
chr1_-_219982081 0.209 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr4_-_68793928 0.209 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr2_-_208736533 0.208 NM_014617
CRYGA
crystallin, gamma A
chr11_+_62893836 0.205 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr17_-_78249750 0.205 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr12_-_98072602 0.205 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr15_-_38185865 0.205 NM_033503
BMF
Bcl2 modifying factor
chr7_-_44854222 0.205 NM_012412
NM_138635
NM_201436
NM_201516
NM_201517
H2AFV




H2A histone family, member V




chr14_-_21064182 0.204 SALL2
sal-like 2 (Drosophila)
chr17_+_37373195 0.203


chr22_+_38652555 0.203 GRAP2
GRB2-related adaptor protein 2
chr20_-_60415729 0.203 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr17_+_70495318 0.202 NM_014603
CDR2L
cerebellar degeneration-related protein 2-like
chr7_-_27171673 0.202 NM_152739
HOXA9
homeobox A9
chrX_+_49013424 0.202 PPP1R3F
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr11_-_58255944 0.201 NM_005838
NM_201648
GLYAT

glycine-N-acyltransferase

chr1_+_43888382 0.201 NM_014663
KDM4A
lysine (K)-specific demethylase 4A
chr16_-_73366200 0.200 NM_024306
FA2H
fatty acid 2-hydroxylase
chr6_-_139737042 0.199 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr18_-_21186107 0.198 NM_015461
ZNF521
zinc finger protein 521
chr19_-_10352212 0.198 NM_003331
TYK2
tyrosine kinase 2
chr16_+_28869628 0.197 NM_032815
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr13_+_92677012 0.195 NM_005708
GPC6
glypican 6
chr14_+_19365447 0.195 NM_001004723
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr19_-_17275083 0.195 NM_024527
ABHD8
abhydrolase domain containing 8

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.79 1.25e-05 GO:0007606 sensory perception of chemical stimulus
1.81 2.85e-05 GO:0007608 sensory perception of smell
1.18 5.38e-05 GO:0032501 multicellular organismal process
1.51 5.82e-04 GO:0007600 sensory perception
1.26 1.22e-03 GO:0010468 regulation of gene expression
1.24 2.33e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.12 2.73e-02 GO:0050896 response to stimulus
1.23 3.18e-02 GO:0010556 regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 1.87e-06 GO:0005634 nucleus
1.32 6.06e-03 GO:0005654 nucleoplasm
1.23 8.53e-03 GO:0044428 nuclear part
1.24 3.65e-02 GO:0031981 nuclear lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.88 1.33e-06 GO:0004984 olfactory receptor activity
1.49 1.06e-05 GO:0030528 transcription regulator activity
1.45 1.47e-04 GO:0001071 nucleic acid binding transcription factor activity
1.45 1.47e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.26 5.13e-04 GO:0003677 DNA binding
1.21 6.26e-04 GO:0003676 nucleic acid binding
1.38 3.03e-02 GO:0004930 G-protein coupled receptor activity