Motif ID: SOX2.p2

Z-value: 1.069


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_182912405-0.342.1e-01Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_39484073 1.714 NM_182935
 MOBP
myelin-associated oligodendrocyte basic protein
chr11_-_16380967 1.703 NM_001145819
NM_017508
 SOX6

SRY (sex determining region Y)-box 6

chr1_-_51660328 1.633 NM_001159969
 EPS15
epidermal growth factor receptor pathway substrate 15
chr2_+_169631777 1.526 NM_199204
 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_-_7923464 1.331 NM_001561
 TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr7_+_128802719 1.327 NM_001130722
 AHCYL2
adenosylhomocysteinase-like 2
chr1_+_181028016 1.195 NM_030769
 NPL
N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
chr8_-_38324809 1.160 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr7_+_106292932 1.157 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr22_-_25344037 1.155 CRYBB1
crystallin, beta B1
chr3_-_3127057 1.143 NM_000564
NM_175724
NM_175725
NM_175726
NM_175727
NM_175728
 IL5RA





interleukin 5 receptor, alpha





chr15_-_48198697 1.095 NM_024837
 ATP8B4
ATPase, class I, type 8B, member 4
chr1_-_41398126 1.066 NM_001172222
 SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr7_+_106292975 1.057 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr4_+_71806538 1.027 NM_001037442
NM_014961
 RUFY3

RUN and FYVE domain containing 3

chr21_+_34112456 1.017 ITSN1
intersectin 1 (SH3 domain protein)
chr7_-_112515068 1.006 NM_001146265
NM_018970
 GPR85

G protein-coupled receptor 85

chr10_-_61570665 0.992 NM_001149
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr22_-_25343959 0.990 NM_001887
 CRYBB1
crystallin, beta B1
chr7_-_112515035 0.989 GPR85
G protein-coupled receptor 85

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.20 7.91e-03 GO:0010638 positive regulation of organelle organization
1.69 1.31e-02 GO:0033043 regulation of organelle organization
1.16 8.12e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.43 2.77e-03 GO:0000932 cytoplasmic mRNA processing body
3.07 1.11e-04 GO:0035770 RNA granule
1.31 4.95e-04 GO:0005856 cytoskeleton
1.22 6.67e-04 GO:0043228 non-membrane-bounded organelle
1.22 6.67e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.14 2.19e-04 GO:0005634 nucleus
1.03 1.13e-02 GO:0044464 cell part
1.03 1.17e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.33 1.58e-02 GO:0031625 ubiquitin protein ligase binding
1.59 9.63e-03 GO:0003712 transcription cofactor activity
1.58 1.07e-02 GO:0000988 protein binding transcription factor activity
1.58 1.07e-02 GO:0000989 transcription factor binding transcription factor activity
1.43 3.93e-03 GO:0019899 enzyme binding
1.17 2.43e-02 GO:0003676 nucleic acid binding
1.09 4.11e-02 GO:0005515 protein binding