Motif ID: SOX5.p2

Z-value: 1.156


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX5chr12_-_236287740.477.6e-02Click!


Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_16380967 5.576 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr7_+_128802719 2.521 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr11_-_123353607 2.408 NM_001004474
OR10S1
olfactory receptor, family 10, subfamily S, member 1
chr8_-_38324809 2.099 WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr7_-_16471817 2.065 NM_015464
SOSTDC1
sclerostin domain containing 1
chr21_+_42492867 1.703 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr1_+_207668787 1.423 NM_001104548
LOC642587
NPC-A-5
chr11_+_20005704 1.420 NAV2
neuron navigator 2
chr6_-_29752909 1.294 NM_001109809
ZFP57
zinc finger protein 57 homolog (mouse)
chr17_+_63252704 1.283 BPTF
bromodomain PHD finger transcription factor
chr19_-_56164628 1.281 NM_002774
KLK6
kallikrein-related peptidase 6
chr6_-_49712483 1.242 NM_000324
RHAG
Rh-associated glycoprotein
chr1_+_116727514 1.236 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr10_-_32707549 1.230 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr2_+_169631777 1.229 NM_199204
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_-_191422346 1.204 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_-_198643885 1.197 ZNF281
zinc finger protein 281
chr17_-_71285992 1.197 H3F3B
H3 histone, family 3B (H3.3B)
chr2_-_160181206 1.163 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr10_+_5976354 1.126 NM_032807
FBXO18
F-box protein, helicase, 18
chr13_-_83354425 1.076 SLITRK1
SLIT and NTRK-like family, member 1
chr9_+_126460511 1.073


chr9_+_134884627 1.069 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr2_-_157890400 1.063 NM_020711
ERMN
ermin, ERM-like protein
chr12_+_68028397 1.056 NM_000239
LYZ
lysozyme
chr4_-_76817635 1.050 NM_203504
NM_203505
G3BP2

GTPase activating protein (SH3 domain) binding protein 2

chr5_-_147266257 1.045 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr1_-_31117948 1.037 SDC3
syndecan 3
chr3_+_46591048 1.036 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr12_+_68028407 1.028 LYZ
lysozyme
chr17_-_36996611 1.027 NM_000526
KRT14
keratin 14
chr13_-_83354474 1.003 NM_052910
SLITRK1
SLIT and NTRK-like family, member 1
chr6_+_29902734 1.002 NM_002127
HLA-G
major histocompatibility complex, class I, G
chrX_-_151370325 0.978 NM_000808
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr6_+_12398514 0.931 NM_001168319
NM_001955
EDN1

endothelin 1

chr17_+_63252668 0.921 BPTF
bromodomain PHD finger transcription factor
chr1_+_151270301 0.913 NM_003125
SPRR1B
small proline-rich protein 1B
chr3_+_138159396 0.912 NM_144717
IL20RB
interleukin 20 receptor beta
chr1_-_150564302 0.896 NM_002016
FLG
filaggrin
chr3_-_57209319 0.868 NM_003865
HESX1
HESX homeobox 1
chr7_-_26198673 0.865 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr20_-_60435983 0.851 NM_080833
C20orf151
chromosome 20 open reading frame 151
chr5_-_148738980 0.843 NM_014443
IL17B
interleukin 17B
chr4_-_40211324 0.842 RBM47
RNA binding motif protein 47
chr11_+_56224436 0.838 NM_001005213
NM_001013358
OR9G1
OR9G9
olfactory receptor, family 9, subfamily G, member 1
olfactory receptor, family 9, subfamily G, member 9
chr1_-_198644111 0.828 ZNF281
zinc finger protein 281
chr1_-_26070330 0.819 NM_178422
PAQR7
progestin and adipoQ receptor family member VII
chr10_+_63331018 0.811 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chrX_+_70419766 0.806 NM_001145408
NM_001145409
NM_001145410
NM_007363
NONO



non-POU domain containing, octamer-binding



chr1_-_108032645 0.784 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr1_-_166149867 0.775 NM_001167749
NM_018417
ADCY10

adenylate cyclase 10 (soluble)

chr17_-_53847937 0.773 RNF43
ring finger protein 43
chr9_-_85773899 0.771 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr9_-_129752687 0.770 NM_203305
FAM102A
family with sequence similarity 102, member A
chr7_-_16811131 0.761 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr1_+_148603208 0.734 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr10_+_63331401 0.730 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_-_21375891 0.704 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_-_16411690 0.702 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr1_+_166516901 0.701 NM_005149
TBX19
T-box 19
chr1_+_183281173 0.700 NM_007212
RNF2
ring finger protein 2
chr20_+_31613800 0.696 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr3_-_150993299 0.690 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr1_+_165565006 0.689 POU2F1
POU class 2 homeobox 1
chr7_+_156128431 0.685 NM_001184997
RNF32
ring finger protein 32
chrX_-_116991728 0.683 NM_033495
NM_001168300
KLHL13

kelch-like 13 (Drosophila)

chrX_+_135441970 0.680 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr5_-_121842680 0.662


chr6_-_116973465 0.660 NM_001139444
BET3L
BET3 like (S. cerevisiae)
chr1_-_21375939 0.658 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr10_-_105835609 0.655 NM_000494
COL17A1
collagen, type XVII, alpha 1
chr11_-_4555625 0.648 NM_144663
C11orf40
chromosome 11 open reading frame 40
chr18_+_59405513 0.640 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr2_-_99238001 0.637 NM_175735
LYG2
lysozyme G-like 2
chr6_-_135312899 0.636 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr1_+_165564904 0.633 NM_001198783
POU2F1
POU class 2 homeobox 1
chr22_+_38652555 0.630 GRAP2
GRB2-related adaptor protein 2
chr2_+_62787534 0.618 NM_001142614
EHBP1
EH domain binding protein 1
chr19_+_12810258 0.614 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr2_-_225073357 0.612 CUL3
cullin 3
chr6_-_41276901 0.600 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chrX_+_105823723 0.596 NM_024539
RNF128
ring finger protein 128
chr20_+_58004811 0.583 NM_021810
CDH26
cadherin 26
chrX_+_15435351 0.578 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr8_-_11742668 0.575


chr12_-_23995220 0.574 SOX5
SRY (sex determining region Y)-box 5
chr11_+_5925152 0.565 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr11_+_65026382 0.555


chr10_+_49279647 0.550 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr11_+_64950074 0.540 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr3_+_182900081 0.538 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr10_+_49184658 0.538 MAPK8
mitogen-activated protein kinase 8
chr17_-_36113502 0.538 NM_019016
KRT24
keratin 24
chr2_+_102401580 0.536 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr10_-_105835525 0.535 COL17A1
collagen, type XVII, alpha 1
chr4_+_35959638 0.532 NM_001136536
DTHD1
death domain containing 1
chr1_+_87569889 0.530


chr2_+_27573206 0.524 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr19_+_54776398 0.522 NM_000951
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr12_-_69434650 0.520 PTPRR
protein tyrosine phosphatase, receptor type, R
chr3_+_186529376 0.516 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr17_-_59817456 0.514 PECAM1
platelet/endothelial cell adhesion molecule
chr3_-_143230124 0.511 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr5_+_147562531 0.510 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr4_-_76817587 0.510 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr7_+_123036312 0.509 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr17_-_36074812 0.505 NM_152349
KRT222
keratin 222
chr14_-_72563497 0.503 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr14_+_19761708 0.502 NM_001004480
OR11H6
olfactory receptor, family 11, subfamily H, member 6
chr16_+_54158084 0.499 NM_032330
CAPNS2
calpain, small subunit 2
chr1_+_61319976 0.498 NM_001145512
NFIA
nuclear factor I/A
chr1_+_559129 0.491


chr6_-_136889302 0.483 MAP7
microtubule-associated protein 7
chr12_-_10453409 0.480 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 read-through transcript
killer cell lectin-like receptor subfamily C, member 4
chr3_+_157877146 0.476 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr7_-_100077072 0.476 NM_003227
TFR2
transferrin receptor 2
chr4_-_122304925 0.464 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr1_+_173111306 0.463 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr12_-_69434598 0.463 NM_130846
PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_137701122 0.462 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr2_+_203207912 0.460 FAM117B
family with sequence similarity 117, member B
chr12_-_23995109 0.459 SOX5
SRY (sex determining region Y)-box 5
chr4_-_76817582 0.456 G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr9_+_95886558 0.451 NM_152422
PTPDC1
protein tyrosine phosphatase domain containing 1
chr12_-_120725210 0.451 LOC338799
hypothetical LOC338799
chr6_-_138862273 0.449


chr1_+_61697209 0.446 NFIA
nuclear factor I/A
chr13_-_98428244 0.446 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr3_-_15814678 0.446 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr7_-_96471544 0.445 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr8_-_110724594 0.444 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr10_-_116241572 0.443


chr6_-_130578110 0.436 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr8_+_102573837 0.436 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr1_+_8928508 0.433 NM_001215
CA6
carbonic anhydrase VI
chr1_+_87569959 0.433 LMO4
LIM domain only 4
chr22_+_38213174 0.433 NM_001098270
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr2_+_108604111 0.431 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr21_+_38550739 0.427 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_150805852 0.422 NM_178435
LCE3E
late cornified envelope 3E
chr15_-_91078307 0.421 FAM174B
family with sequence similarity 174, member B
chr7_-_83662152 0.421 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr12_-_49708279 0.420 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr4_-_68678181 0.420 NM_207407
TMPRSS11F
transmembrane protease, serine 11F
chr16_-_3870121 0.414 NM_001079846
NM_004380
CREBBP

CREB binding protein

chr9_+_95886625 0.414 PTPDC1
protein tyrosine phosphatase domain containing 1
chr7_-_107558021 0.413 NM_007356
LAMB4
laminin, beta 4
chr1_-_57057956 0.413 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr11_-_26550243 0.411 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr17_-_1359745 0.409 INPP5K
inositol polyphosphate-5-phosphatase K
chr8_+_26206648 0.408 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr6_-_138862271 0.406 NM_001144060
NHSL1
NHS-like 1
chr11_+_93940121 0.405 NM_152431
PIWIL4
piwi-like 4 (Drosophila)
chr16_+_24459173 0.403 RBBP6
retinoblastoma binding protein 6
chr6_+_57019269 0.402 NM_020931
KIAA1586
KIAA1586
chr21_-_30510113 0.402 NM_199328
CLDN8
claudin 8
chr15_+_41265429 0.401 NM_037370
CCNDBP1
cyclin D-type binding-protein 1
chr1_+_29113589 0.401 NM_001166006
EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr16_-_69876262 0.400 FTSJD1
FtsJ methyltransferase domain containing 1
chr10_-_123346148 0.399 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr1_-_51660328 0.394 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr13_+_92677012 0.393 NM_005708
GPC6
glypican 6
chr9_+_96807107 0.392 C9orf3
chromosome 9 open reading frame 3
chr12_-_28016182 0.391 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr22_+_17498320 0.386 NM_053006
TSSK2
testis-specific serine kinase 2
chr22_+_21852551 0.386 NM_004327
NM_021574
BCR

breakpoint cluster region

chr2_+_233417348 0.383 GIGYF2
GRB10 interacting GYF protein 2
chrX_-_49852397 0.382 NM_003886
AKAP4
A kinase (PRKA) anchor protein 4
chr15_-_40089736 0.380 NM_001080490
PLA2G4E
phospholipase A2, group IVE
chr12_-_69317441 0.378 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_+_183970093 0.376 NM_031935
HMCN1
hemicentin 1
chr9_+_138810610 0.376 NM_001039374
KIAA1984
KIAA1984
chr19_-_14771947 0.376 NM_198944
OR7C1
olfactory receptor, family 7, subfamily C, member 1
chr8_+_22266256 0.375 PIWIL2
piwi-like 2 (Drosophila)
chr2_+_113452066 0.375 NM_019618
IL1F9
interleukin 1 family, member 9
chr12_-_49763405 0.375 CSRNP2
cysteine-serine-rich nuclear protein 2
chr1_-_199742589 0.374 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr3_+_142587973 0.374


chr9_+_102275310 0.372 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr4_+_77575276 0.370 NM_020859
SHROOM3
shroom family member 3
chr5_+_133735004 0.369 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr7_-_142369519 0.368 KEL
Kell blood group, metallo-endopeptidase
chr11_+_73037382 0.368 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr3_-_14963943 0.367


chr5_+_34723420 0.366 NM_001145523
RAI14
retinoic acid induced 14
chr14_-_54948290 0.365 NM_014924
ATG14
ATG14 autophagy related 14 homolog (S. cerevisiae)
chr9_+_102275455 0.364 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_13992351 0.363 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr3_-_129777618 0.363 NM_007354
C3orf27
chromosome 3 open reading frame 27
chr7_-_107667728 0.362 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr22_-_34566367 0.361 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr1_+_151051070 0.360 NM_178349
LCE1B
late cornified envelope 1B
chr15_+_83467295 0.358 PDE8A
phosphodiesterase 8A
chr9_-_40782062 0.357 NM_033160
ZNF658
zinc finger protein 658
chr6_+_47732181 0.357 NM_153839
GPR111
G protein-coupled receptor 111
chr20_+_58064360 0.355 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr6_-_150253729 0.353 NM_139165
RAET1E
retinoic acid early transcript 1E
chr2_+_74914742 0.351 HK2
hexokinase 2
chr12_-_69434330 0.351 PTPRR
protein tyrosine phosphatase, receptor type, R
chr1_+_198975227 0.350 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.74 7.36e-03 GO:0004984 olfactory receptor activity