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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: SP1.p2

Z-value: 2.564

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_659766	3.004	NM_001040134 NM_002579	PALM	paralemmin
chr7_-_158073121	2.224	NM_002847 NM_130842 NM_130843	PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2
chr9_-_122679387	2.113	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr17_-_76622967	2.083		FLJ90757	hypothetical LOC440465
chr20_-_62151216	1.957	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr19_-_55524445	1.894	NM_004977	KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3
chr22_+_18081968	1.855	NM_002688	SEPT5	septin 5
chr1_+_16247870	1.767	NM_001165945	CLCNKB	chloride channel Kb
chr9_+_132961723	1.716		AIF1L	allograft inflammatory factor 1-like
chr3_+_37878647	1.712	NM_001008392 NM_005808	CTDSPL	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr16_-_960982	1.663	NM_022773	LMF1	lipase maturation factor 1
chr9_+_131974506	1.618	NM_014286	NCS1	neuronal calcium sensor 1
chr2_+_42128521	1.597	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr19_+_57492236	1.595	NM_144684	ZNF480	zinc finger protein 480
chr6_+_44295219	1.570	NM_001078174 NM_004955	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr2_+_238265791	1.566		LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr22_+_48951286	1.516	NM_001160300 NM_052839	PANX2	pannexin 2
chr19_+_59064795	1.504		MYADM	myeloid-associated differentiation marker
chr5_-_140875591	1.483		DIAPH1	diaphanous homolog 1 (Drosophila)
chr22_-_21231421	1.475	NM_206955 NM_206956 NM_006115 NM_206953 NM_206954	PRAME	preferentially expressed antigen in melanoma
chr21_+_43267760	1.437		PKNOX1	PBX/knotted 1 homeobox 1
chr7_-_150305933	1.422	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_+_34965436	1.414	NM_001012339 NM_194283	DNAJC21	DnaJ (Hsp40) homolog, subfamily C, member 21
chr16_-_960796	1.411		LMF1	lipase maturation factor 1
chr1_-_38243747	1.405	NM_004468	FHL3	four and a half LIM domains 3
chr17_-_46298671	1.395		TOB1	transducer of ERBB2, 1
chr1_+_15123165	1.382	NM_001018000	KAZN	kazrin, periplakin interacting protein
chr14_+_23937766	1.372	NM_025081	NYNRIN	NYN domain and retroviral integrase containing
chr22_+_21742364	1.370	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr19_+_11327173	1.360		LPPR2	lipid phosphate phosphatase-related protein type 2
chr19_-_2979901	1.350	NM_003260	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr12_+_6292077	1.346	NM_001144857	PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr6_-_30762957	1.308		KIAA1949	KIAA1949
chr17_-_75427644	1.298	NM_003655	CBX4	chromobox homolog 4
chr22_-_17489912	1.288	NM_001173533 NM_001173534 NM_001184781 NM_005137	DGCR2	DiGeorge syndrome critical region gene 2
chr7_-_150847529	1.286		RHEB	Ras homolog enriched in brain
chr1_-_11674264	1.254	NM_001127325	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)
chr16_-_3225360	1.254	NM_001145448 NM_198088 NM_001145446 NM_198087	ZNF200	zinc finger protein 200
chr22_-_17489718	1.252		DGCR2	DiGeorge syndrome critical region gene 2
chr12_+_88627601	1.247		LOC338758	hypothetical LOC338758
chr3_+_47004457	1.240		NBEAL2	neurobeachin-like 2
chr6_+_4721825	1.221		CDYL	chromodomain protein, Y-like
chr7_-_44152232	1.218		GCK	glucokinase (hexokinase 4)
chr3_-_112796855	1.212	NM_024508	ZBED2	zinc finger, BED-type containing 2
chr2_-_179024002	1.201	NM_003690	PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_+_71033339	1.198	NM_001015002 NM_001031803 NM_004524	LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr1_+_205137410	1.196	NM_001185156 NM_001185157 NM_001185158 NM_006850	IL24	interleukin 24
chr10_+_104145421	1.193	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_226404037	1.187	NM_020435	GJC2	gap junction protein, gamma 2, 47kDa
chr17_-_78199384	1.187	NM_019613	WDR45L	WDR45-like
chr6_+_44203335	1.186	NM_018426	TMEM63B	transmembrane protein 63B
chr9_+_132961683	1.183	NM_001185095 NM_001185096 NM_031426	AIF1L	allograft inflammatory factor 1-like
chr19_+_59064471	1.180	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr19_-_11169184	1.173	NM_001136191	KANK2	KN motif and ankyrin repeat domains 2
chr1_-_199259133	1.162		KIF21B	kinesin family member 21B
chr5_+_176446425	1.160	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr11_+_63829616	1.158	NM_004451	ESRRA	estrogen-related receptor alpha
chr21_+_46226072	1.156	NM_001848	COL6A1	collagen, type VI, alpha 1
chr21_+_43267703	1.142	NM_004571	PKNOX1	PBX/knotted 1 homeobox 1
chr19_+_59062982	1.137		MYADM	myeloid-associated differentiation marker
chr9_+_138341752	1.136	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr1_+_32979930	1.136	NM_020888	KIAA1522	KIAA1522
chr20_-_62181231	1.134	NM_005873	RGS19	regulator of G-protein signaling 19
chr1_-_38243716	1.131		FHL3	four and a half LIM domains 3
chr17_+_18320822	1.130	NM_001040078	LGALS9B LGALS9C	lectin, galactoside-binding, soluble, 9B lectin, galactoside-binding, soluble, 9C
chr5_-_141973875	1.115	NM_033137	FGF1	fibroblast growth factor 1 (acidic)
chr6_+_35528093	1.111	NM_021922	FANCE	Fanconi anemia, complementation group E
chr9_+_102275310	1.108	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr5_-_10814344	1.102	NM_004394	DAP	death-associated protein
chr16_+_70117523	1.101	NM_005769 NM_001166395	CHST4	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
chr9_+_130142746	1.098		SLC27A4	solute carrier family 27 (fatty acid transporter), member 4
chr20_-_62071584	1.098	NM_020713	ZNF512B	zinc finger protein 512B
chr22_+_21742727	1.097		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr15_-_31147376	1.096	NM_001103184	FMN1	formin 1
chr8_+_146248593	1.096	NM_023080	C8orf33	chromosome 8 open reading frame 33
chrX_-_153397566	1.088	NM_001171132 NM_001171133 NM_001171134 NM_021806	FAM3A	family with sequence similarity 3, member A
chr22_+_19649417	1.086	NM_001018060 NM_144704	AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr19_+_11327061	1.085	NM_001170635 NM_022737	LPPR2	lipid phosphate phosphatase-related protein type 2
chr12_-_54408391	1.076		CD63	CD63 molecule
chr17_+_34114924	1.072		MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr15_-_100082134	1.072	NM_152334	TARSL2	threonyl-tRNA synthetase-like 2
chr6_-_41810712	1.069	NM_007162	TFEB	transcription factor EB
chr19_-_60360768	1.068	NM_000363	TNNI3	troponin I type 3 (cardiac)
chr9_-_122679283	1.067		PHF19	PHD finger protein 19
chr20_+_34523231	1.065	NM_001042486	DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr7_-_143230096	1.065	NM_014719	FAM115A	family with sequence similarity 115, member A
chr19_-_4016467	1.056		ZBTB7A	zinc finger and BTB domain containing 7A
chr6_-_15356865	1.054
chr19_+_59062962	1.045		MYADM	myeloid-associated differentiation marker
chr22_-_20419975	1.044	NM_013313	YPEL1	yippee-like 1 (Drosophila)
chr6_-_30763057	1.043	NM_001134870	KIAA1949	KIAA1949
chr12_+_56291484	1.043	NM_182947	ARHGEF25	Rho guanine nucleotide exchange factor (GEF) 25
chr19_+_14405216	1.034		PKN1	protein kinase N1
chr22_+_21852743	1.034		BCR	breakpoint cluster region
chr22_+_20101661	1.029	NM_015094	HIC2	hypermethylated in cancer 2
chr19_+_53951155	1.012	NM_019113	FGF21	fibroblast growth factor 21
chr17_+_72789086	1.009	NM_001113491	SEPT9	septin 9
chr6_+_35528127	1.008		FANCE	Fanconi anemia, complementation group E
chr19_+_60691733	1.007		SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr11_+_44543716	1.006	NM_001024844 NM_002231	CD82	CD82 molecule
chr7_-_100325209	1.003	NM_001015072	UFSP1	UFM1-specific peptidase 1 (non-functional)
chr10_-_62431203	1.002		RHOBTB1	Rho-related BTB domain containing 1
chr1_+_165330710	1.002	NM_001080426	DUSP27	dual specificity phosphatase 27 (putative)
chr19_-_11169457	0.999		KANK2	KN motif and ankyrin repeat domains 2
chr21_+_36679533	0.992	NM_005441	CHAF1B	chromatin assembly factor 1, subunit B (p60)
chr16_+_10878539	0.989	NM_000246	CIITA	class II, major histocompatibility complex, transactivator
chr20_+_34523555	0.988	NM_183006	DLGAP4	discs, large (Drosophila) homolog-associated protein 4
chr6_-_150253729	0.983	NM_139165	RAET1E	retinoic acid early transcript 1E
chr10_+_99322187	0.975	NM_001129981 NM_020349	ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)
chr16_-_53520208	0.974		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr7_-_50828608	0.973	NM_001001555	GRB10	growth factor receptor-bound protein 10
chr10_-_43224604	0.972	NM_004966 NM_001098204	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr17_+_72648696	0.961		SEC14L1	SEC14-like 1 (S. cerevisiae)
chr1_-_151614681	0.958	NM_005621	S100A12	S100 calcium binding protein A12
chr19_-_44503328	0.957
chr5_-_142057692	0.957	NM_001144934 NM_001144935	FGF1	fibroblast growth factor 1 (acidic)
chr7_-_127833231	0.951	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr1_-_23683214	0.946		ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr22_-_18384251	0.938	NM_001670	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome
chr7_-_150306169	0.932		KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_200124412	0.931	NM_198149	SHISA4	shisa homolog 4 (Xenopus laevis)
chr2_-_175060001	0.924	NM_001033045 NM_152529	GPR155	G protein-coupled receptor 155
chr12_-_123023052	0.922	NM_025140	CCDC92	coiled-coil domain containing 92
chr17_+_75366524	0.922	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr11_+_1812115	0.920	NM_138567	SYT8	synaptotagmin VIII
chr1_-_23683308	0.919	NM_001143778 NM_017707	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr14_+_51025604	0.918	NM_001042481	FRMD6	FERM domain containing 6
chr7_-_104816487	0.917
chr10_+_76256305	0.916	NM_012330	MYST4	MYST histone acetyltransferase (monocytic leukemia) 4
chr9_+_102275455	0.915		TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr21_-_46472835	0.915		LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr16_+_2016807	0.914	NM_001130012 NM_004785	SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr3_+_43303005	0.912	NM_001100594 NM_017719	SNRK	SNF related kinase
chr6_+_138230045	0.909	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr5_+_139008667	0.907		CXXC5	CXXC finger protein 5
chr7_-_44152252	0.906		GCK	glucokinase (hexokinase 4)
chr4_+_106693225	0.903	NM_017700	ARHGEF38	Rho guanine nucleotide exchange factor (GEF) 38
chr15_+_64481270	0.902		MAP2K1	mitogen-activated protein kinase kinase 1
chr19_-_51168396	0.901	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr20_+_62181878	0.895	NM_000913 NM_182647	OPRL1	opiate receptor-like 1
chr11_-_119504726	0.895		TRIM29	tripartite motif containing 29
chr20_+_30813851	0.888	NM_006892 NM_175848 NM_175849	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta
chr11_+_15093059	0.887	NM_001042536	INSC	inscuteable homolog (Drosophila)
chr1_-_9892852	0.885	NM_001012329 NM_020248	CTNNBIP1	catenin, beta interacting protein 1
chr11_+_44543788	0.885		CD82	CD82 molecule
chr19_-_242168	0.884	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr1_+_66570363	0.884	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chr16_-_87244896	0.878	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr1_-_20684858	0.877		CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr6_+_3204133	0.874	NM_001128591 NM_001128592 NM_001135750	PSMG4	proteasome (prosome, macropain) assembly chaperone 4
chr19_+_10404110	0.873	NM_001111309	PDE4A	phosphodiesterase 4A, cAMP-specific
chr22_+_19649460	0.873		AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr12_-_13147839	0.872	NM_001080554 NM_001080555	GSG1	germ cell associated 1
chr20_+_36867708	0.871	NM_001172735 NM_015568	PPP1R16B	protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr1_+_115986096	0.870	NM_001172411 NM_138959	VANGL1	vang-like 1 (van gogh, Drosophila)
chr5_+_176170041	0.869	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr6_-_44203131	0.868		MRPL14	mitochondrial ribosomal protein L14
chr7_+_2524022	0.866	NM_002304	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_-_34635091	0.866
chr16_-_371823	0.866	NM_021259	TMEM8A	transmembrane protein 8A
chr17_-_3408038	0.864	NM_145068	TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr3_+_47397475	0.862	NM_015466	PTPN23	protein tyrosine phosphatase, non-receptor type 23
chr7_-_150847624	0.860		RHEB	Ras homolog enriched in brain
chr3_+_46386636	0.858	NM_000579 NM_001100168	CCR5	chemokine (C-C motif) receptor 5
chr12_-_122415327	0.857		SBNO1	strawberry notch homolog 1 (Drosophila)
chr16_+_80036275	0.856	NM_198390	CMIP	c-Maf-inducing protein
chr6_+_3204184	0.856		PSMG4	proteasome (prosome, macropain) assembly chaperone 4
chr17_+_72648580	0.855	NM_001039573 NM_001143998 NM_001143999 NM_003003	SEC14L1	SEC14-like 1 (S. cerevisiae)
chr1_+_183281173	0.854	NM_007212	RNF2	ring finger protein 2
chr1_-_1233109	0.854	NM_030649	ACAP3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr2_-_74915722	0.853
chr9_+_129962292	0.852	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr16_-_3008162	0.852	NM_021195	CLDN6	claudin 6
chr19_-_56585603	0.852	NM_001193623	LOC147646	hypothetical protein LOC147646
chr22_-_17545872	0.847		SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr16_+_87047159	0.844		ZFPM1	zinc finger protein, multitype 1
chr22_+_18090118	0.844		SEPT5-GP1BB	SEPT5-GP1BB read-through transcript
chr22_-_20551722	0.843		MAPK1	mitogen-activated protein kinase 1
chr5_+_150612805	0.843	NM_000405 NM_001167607	GM2A	GM2 ganglioside activator
chr22_-_41357380	0.842
chr5_+_140848905	0.842	NM_018929 NM_032407	PCDHGC5	protocadherin gamma subfamily C, 5
chr6_+_44299482	0.841		SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chr2_-_219558517	0.838	NM_017521	FEV	FEV (ETS oncogene family)
chr7_-_86526880	0.837	NM_001142749	KIAA1324L	KIAA1324-like
chr7_-_150847698	0.837		RHEB	Ras homolog enriched in brain
chr10_-_43224312	0.836	NM_001098205	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr22_+_35586950	0.835	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr10_+_13182061	0.834	NM_001008211 NM_001008212 NM_001008213 NM_021980	OPTN	optineurin
chr14_+_104267270	0.834	NM_199165	ADSSL1	adenylosuccinate synthase like 1
chr22_-_43040063	0.832	NM_001099294	KIAA1644	KIAA1644
chr8_-_145187553	0.829	NM_017570	OPLAH	5-oxoprolinase (ATP-hydrolysing)
chr8_-_41641881	0.828	NM_001142445 NM_020478 NM_020480	ANK1	ankyrin 1, erythrocytic
chr12_-_107775400	0.827		SSH1	slingshot homolog 1 (Drosophila)
chr21_-_45173061	0.827	NM_001127491	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_+_3045528	0.824		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr12_-_30798714	0.823	NM_001002259 NM_023925 NM_032156	CAPRIN2	caprin family member 2
chr2_+_112529371	0.820		TMEM87B	transmembrane protein 87B
chr3_-_197120276	0.818	NM_005781	TNK2	tyrosine kinase, non-receptor, 2
chr11_-_72057755	0.818	NM_001146209	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr2_+_46623396	0.818		RHOQ	ras homolog gene family, member Q

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	3.52e-33	GO:0009987	cellular process
1.13	4.94e-24	GO:0044237	cellular metabolic process
1.16	1.05e-23	GO:0044260	cellular macromolecule metabolic process
1.12	4.02e-20	GO:0044238	primary metabolic process
1.11	8.66e-20	GO:0050794	regulation of cellular process
1.10	2.68e-19	GO:0065007	biological regulation
1.10	5.27e-19	GO:0050789	regulation of biological process
1.10	2.28e-18	GO:0008152	metabolic process
1.15	1.73e-17	GO:0019222	regulation of metabolic process
1.16	2.25e-17	GO:0031323	regulation of cellular metabolic process
1.16	3.30e-17	GO:0080090	regulation of primary metabolic process
1.13	1.05e-16	GO:0043170	macromolecule metabolic process
1.16	6.45e-16	GO:0060255	regulation of macromolecule metabolic process
1.19	4.17e-15	GO:0044267	cellular protein metabolic process
1.21	4.57e-13	GO:0006464	protein modification process
1.19	4.98e-13	GO:0048523	negative regulation of cellular process
1.29	9.54e-13	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.18	1.28e-12	GO:0048522	positive regulation of cellular process
1.16	5.23e-12	GO:0048518	positive regulation of biological process
1.17	8.70e-12	GO:0048519	negative regulation of biological process
1.19	3.67e-11	GO:0043412	macromolecule modification
1.16	5.61e-11	GO:0010468	regulation of gene expression
1.21	7.41e-11	GO:0023051	regulation of signaling
1.16	1.16e-10	GO:0071842	cellular component organization at cellular level
1.16	1.44e-10	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.33	2.16e-10	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.15	1.00e-09	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	1.01e-09	GO:0071841	cellular component organization or biogenesis at cellular level
1.14	1.38e-09	GO:0019538	protein metabolic process
1.21	1.60e-09	GO:0009966	regulation of signal transduction
1.32	1.63e-09	GO:0010558	negative regulation of macromolecule biosynthetic process
1.19	3.70e-09	GO:0006996	organelle organization
1.15	4.46e-09	GO:0010556	regulation of macromolecule biosynthetic process
1.15	5.10e-09	GO:0031326	regulation of cellular biosynthetic process
1.11	8.36e-09	GO:0051716	cellular response to stimulus
1.13	8.86e-09	GO:0016043	cellular component organization
1.26	1.20e-08	GO:0031324	negative regulation of cellular metabolic process
1.29	1.32e-08	GO:0009890	negative regulation of biosynthetic process
1.30	1.34e-08	GO:0031327	negative regulation of cellular biosynthetic process
1.14	1.45e-08	GO:0051171	regulation of nitrogen compound metabolic process
1.14	1.50e-08	GO:0009889	regulation of biosynthetic process
1.14	1.78e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	1.90e-08	GO:0009058	biosynthetic process
1.25	2.29e-08	GO:0010605	negative regulation of macromolecule metabolic process
1.24	2.50e-08	GO:0009892	negative regulation of metabolic process
1.15	3.02e-08	GO:0051252	regulation of RNA metabolic process
1.23	3.95e-08	GO:0051246	regulation of protein metabolic process
1.23	5.68e-08	GO:0032268	regulation of cellular protein metabolic process
1.12	7.46e-08	GO:0006807	nitrogen compound metabolic process
1.15	8.00e-08	GO:0044249	cellular biosynthetic process
1.12	8.68e-08	GO:0071840	cellular component organization or biogenesis
1.12	1.04e-07	GO:0034641	cellular nitrogen compound metabolic process
1.11	1.26e-07	GO:0023052	signaling
1.12	2.07e-07	GO:0007165	signal transduction
1.25	2.40e-07	GO:0033554	cellular response to stress
1.32	3.08e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.15	7.29e-07	GO:0006355	regulation of transcription, DNA-dependent
1.29	7.60e-07	GO:0010629	negative regulation of gene expression
1.46	8.15e-07	GO:0048011	nerve growth factor receptor signaling pathway
1.30	1.56e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.14	1.57e-06	GO:0090304	nucleic acid metabolic process
1.28	1.74e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.23	1.91e-06	GO:0008219	cell death
1.23	1.99e-06	GO:0016265	death
1.28	2.02e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	2.13e-06	GO:0035556	intracellular signal transduction
1.27	2.21e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.29	3.48e-06	GO:0051253	negative regulation of RNA metabolic process
1.19	9.81e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.18	1.00e-05	GO:0009893	positive regulation of metabolic process
1.25	1.98e-05	GO:0045595	regulation of cell differentiation
1.15	2.27e-05	GO:0009059	macromolecule biosynthetic process
1.17	2.38e-05	GO:0065009	regulation of molecular function
1.33	2.42e-05	GO:0016568	chromatin modification
1.18	2.91e-05	GO:0031325	positive regulation of cellular metabolic process
1.15	3.08e-05	GO:0034645	cellular macromolecule biosynthetic process
1.42	3.48e-05	GO:0032868	response to insulin stimulus
1.21	4.60e-05	GO:0022008	neurogenesis
1.53	4.69e-05	GO:0008286	insulin receptor signaling pathway
1.41	6.35e-05	GO:0071375	cellular response to peptide hormone stimulus
1.21	6.94e-05	GO:0006351	transcription, DNA-dependent
1.14	8.17e-05	GO:0048583	regulation of response to stimulus
1.31	8.96e-05	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.36	9.06e-05	GO:0051270	regulation of cellular component movement
1.45	1.05e-04	GO:0032869	cellular response to insulin stimulus
1.35	1.19e-04	GO:0032870	cellular response to hormone stimulus
1.25	1.35e-04	GO:0009725	response to hormone stimulus
1.24	1.58e-04	GO:0009719	response to endogenous stimulus
1.36	1.87e-04	GO:0010608	posttranscriptional regulation of gene expression
1.16	1.99e-04	GO:0009056	catabolic process
1.19	2.03e-04	GO:0042127	regulation of cell proliferation
1.23	2.05e-04	GO:0010628	positive regulation of gene expression
1.16	2.07e-04	GO:0007399	nervous system development
1.29	2.65e-04	GO:0032583	regulation of gene-specific transcription
1.17	2.99e-04	GO:0010033	response to organic substance
1.33	3.21e-04	GO:0071495	cellular response to endogenous stimulus
1.32	3.59e-04	GO:0043434	response to peptide hormone stimulus
1.31	3.84e-04	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.22	3.85e-04	GO:0019220	regulation of phosphate metabolic process
1.22	3.85e-04	GO:0051174	regulation of phosphorus metabolic process
1.21	4.19e-04	GO:0031399	regulation of protein modification process
1.18	4.34e-04	GO:0010646	regulation of cell communication
1.18	4.69e-04	GO:0007049	cell cycle
1.20	4.86e-04	GO:0048699	generation of neurons
1.42	5.32e-04	GO:0016569	covalent chromatin modification
1.33	5.76e-04	GO:0060284	regulation of cell development
1.26	6.75e-04	GO:0006974	response to DNA damage stimulus
1.42	6.80e-04	GO:0016570	histone modification
1.22	7.53e-04	GO:0051254	positive regulation of RNA metabolic process
1.34	9.67e-04	GO:0040012	regulation of locomotion
1.13	1.13e-03	GO:0016070	RNA metabolic process
1.18	1.30e-03	GO:0006793	phosphorus metabolic process
1.18	1.30e-03	GO:0006796	phosphate metabolic process
1.17	1.32e-03	GO:0044248	cellular catabolic process
1.25	1.43e-03	GO:0007010	cytoskeleton organization
1.23	1.57e-03	GO:0045893	positive regulation of transcription, DNA-dependent
1.13	1.83e-03	GO:0010467	gene expression
1.12	2.16e-03	GO:0065008	regulation of biological quality
1.34	2.29e-03	GO:0016567	protein ubiquitination
1.34	2.45e-03	GO:2000145	regulation of cell motility
1.20	2.58e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18	2.82e-03	GO:0050793	regulation of developmental process
1.21	2.89e-03	GO:0042325	regulation of phosphorylation
1.22	2.91e-03	GO:0009057	macromolecule catabolic process
1.20	3.03e-03	GO:2000026	regulation of multicellular organismal development
1.34	3.10e-03	GO:0030334	regulation of cell migration
1.32	3.96e-03	GO:0032446	protein modification by small protein conjugation
1.20	4.00e-03	GO:0012501	programmed cell death
1.17	4.04e-03	GO:0043067	regulation of programmed cell death
1.29	4.07e-03	GO:0070647	protein modification by small protein conjugation or removal
1.61	4.59e-03	GO:0007173	epidermal growth factor receptor signaling pathway
1.34	4.67e-03	GO:0030036	actin cytoskeleton organization
1.15	4.69e-03	GO:0051239	regulation of multicellular organismal process
1.17	4.88e-03	GO:0032879	regulation of localization
1.16	4.93e-03	GO:0010941	regulation of cell death
1.20	5.62e-03	GO:0006915	apoptosis
1.27	5.67e-03	GO:0007264	small GTPase mediated signal transduction
1.15	5.86e-03	GO:0050790	regulation of catalytic activity
1.18	5.93e-03	GO:0048468	cell development
1.23	6.71e-03	GO:0044265	cellular macromolecule catabolic process
1.19	7.62e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.16	7.74e-03	GO:0042981	regulation of apoptosis
1.24	7.83e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.40	8.42e-03	GO:0006417	regulation of translation
1.13	8.63e-03	GO:0009653	anatomical structure morphogenesis
1.11	8.66e-03	GO:0030154	cell differentiation
1.18	1.06e-02	GO:0044093	positive regulation of molecular function
1.23	1.10e-02	GO:0051338	regulation of transferase activity
1.62	1.33e-02	GO:0034138	toll-like receptor 3 signaling pathway
1.17	1.33e-02	GO:0032774	RNA biosynthetic process
1.23	1.47e-02	GO:0043549	regulation of kinase activity
1.54	1.57e-02	GO:0043543	protein acylation
1.24	1.57e-02	GO:0072358	cardiovascular system development
1.24	1.57e-02	GO:0072359	circulatory system development
1.20	1.75e-02	GO:0001932	regulation of protein phosphorylation
1.14	1.78e-02	GO:0051641	cellular localization
1.18	1.83e-02	GO:0051128	regulation of cellular component organization
1.20	1.86e-02	GO:0071310	cellular response to organic substance
1.23	1.92e-02	GO:0045859	regulation of protein kinase activity
1.25	1.93e-02	GO:0008285	negative regulation of cell proliferation
1.11	2.03e-02	GO:0048869	cellular developmental process
1.18	2.37e-02	GO:0046907	intracellular transport
1.76	2.42e-02	GO:0017148	negative regulation of translation
1.57	2.45e-02	GO:0006473	protein acetylation
1.20	2.55e-02	GO:0051726	regulation of cell cycle
1.17	3.03e-02	GO:0022402	cell cycle process
1.22	3.09e-02	GO:0000904	cell morphogenesis involved in differentiation
1.09	3.18e-02	GO:0048731	system development
1.08	3.31e-02	GO:0051179	localization
1.18	3.50e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
1.20	4.47e-02	GO:0051276	chromosome organization
1.51	4.56e-02	GO:0018205	peptidyl-lysine modification
1.24	4.78e-02	GO:0007243	intracellular protein kinase cascade
1.24	4.78e-02	GO:0023014	signal transduction via phosphorylation event

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	8.87e-64	GO:0005622	intracellular
1.11	5.67e-63	GO:0044424	intracellular part
1.12	4.30e-43	GO:0043227	membrane-bounded organelle
1.12	1.44e-42	GO:0043231	intracellular membrane-bounded organelle
1.13	2.58e-42	GO:0005737	cytoplasm
1.11	2.24e-41	GO:0043229	intracellular organelle
1.11	2.71e-41	GO:0043226	organelle
1.13	8.17e-25	GO:0044444	cytoplasmic part
1.14	2.24e-24	GO:0005634	nucleus
1.12	3.89e-20	GO:0044446	intracellular organelle part
1.12	8.79e-20	GO:0044422	organelle part
1.22	1.35e-18	GO:0005829	cytosol
1.22	2.14e-16	GO:0031981	nuclear lumen
1.20	1.05e-15	GO:0044428	nuclear part
1.19	2.17e-15	GO:0070013	intracellular organelle lumen
1.18	2.77e-14	GO:0043233	organelle lumen
1.25	4.75e-14	GO:0005654	nucleoplasm
1.18	5.45e-14	GO:0031974	membrane-enclosed lumen
1.03	1.44e-11	GO:0044464	cell part
1.03	1.68e-11	GO:0005623	cell
1.13	3.68e-09	GO:0043234	protein complex
1.27	2.16e-08	GO:0044451	nucleoplasm part
1.11	3.95e-07	GO:0032991	macromolecular complex
1.14	1.00e-06	GO:0031090	organelle membrane
1.25	1.60e-06	GO:0015630	microtubule cytoskeleton
1.20	2.07e-06	GO:0005794	Golgi apparatus
1.16	2.30e-06	GO:0012505	endomembrane system
1.11	5.99e-06	GO:0043228	non-membrane-bounded organelle
1.11	5.99e-06	GO:0043232	intracellular non-membrane-bounded organelle
1.17	9.24e-05	GO:0005783	endoplasmic reticulum
1.22	5.17e-04	GO:0044431	Golgi apparatus part
1.27	1.86e-03	GO:0048471	perinuclear region of cytoplasm
1.23	1.88e-03	GO:0000139	Golgi membrane
1.66	3.24e-03	GO:0034708	methyltransferase complex
1.66	3.24e-03	GO:0035097	histone methyltransferase complex
1.36	4.38e-03	GO:0031252	cell leading edge
1.12	8.10e-03	GO:0005856	cytoskeleton
1.51	1.00e-02	GO:0000790	nuclear chromatin
1.48	1.11e-02	GO:0042470	melanosome
1.48	1.11e-02	GO:0048770	pigment granule
2.02	1.14e-02	GO:0031519	PcG protein complex
1.56	1.37e-02	GO:0000123	histone acetyltransferase complex
1.25	3.69e-02	GO:0015629	actin cytoskeleton

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	8.12e-49	GO:0005515	protein binding
1.07	1.19e-32	GO:0005488	binding
1.10	1.25e-10	GO:0003824	catalytic activity
1.28	1.57e-09	GO:0019899	enzyme binding
1.35	1.46e-05	GO:0016564	transcription repressor activity
1.31	3.90e-05	GO:0000988	protein binding transcription factor activity
1.31	3.90e-05	GO:0000989	transcription factor binding transcription factor activity
1.12	4.70e-05	GO:0000166	nucleotide binding
1.30	5.14e-05	GO:0003712	transcription cofactor activity
1.14	5.92e-05	GO:0016740	transferase activity
1.25	1.10e-04	GO:0008092	cytoskeletal protein binding
1.45	1.39e-04	GO:0004721	phosphoprotein phosphatase activity
1.20	1.45e-04	GO:0016301	kinase activity
1.18	1.83e-04	GO:0030528	transcription regulator activity
1.33	2.05e-04	GO:0008134	transcription factor binding
1.35	3.22e-04	GO:0016791	phosphatase activity
1.21	3.52e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.27	4.16e-04	GO:0004674	protein serine/threonine kinase activity
1.08	4.66e-04	GO:0043169	cation binding
1.08	4.98e-04	GO:0043167	ion binding
1.34	9.63e-04	GO:0019900	kinase binding
1.29	1.04e-03	GO:0042578	phosphoric ester hydrolase activity
1.18	1.14e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.12	1.17e-03	GO:0017076	purine nucleotide binding
1.12	1.18e-03	GO:0032553	ribonucleotide binding
1.12	1.18e-03	GO:0032555	purine ribonucleotide binding
1.08	1.50e-03	GO:0046872	metal ion binding
1.10	1.72e-03	GO:0003677	DNA binding
1.12	1.79e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.11	2.24e-03	GO:0008270	zinc ion binding
1.29	4.44e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.28	4.87e-03	GO:0016563	transcription activator activity
1.16	5.20e-03	GO:0001071	nucleic acid binding transcription factor activity
1.16	5.20e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.23	5.22e-03	GO:0016874	ligase activity
1.10	5.78e-03	GO:0046914	transition metal ion binding
1.18	7.07e-03	GO:0042802	identical protein binding
1.27	9.26e-03	GO:0003779	actin binding
1.31	1.58e-02	GO:0019787	small conjugating protein ligase activity
1.69	1.78e-02	GO:0004722	protein serine/threonine phosphatase activity
1.28	1.78e-02	GO:0016881	acid-amino acid ligase activity
1.08	1.83e-02	GO:0003676	nucleic acid binding
1.31	2.84e-02	GO:0004842	ubiquitin-protein ligase activity
1.17	3.50e-02	GO:0016788	hydrolase activity, acting on ester bonds
1.21	3.83e-02	GO:0030695	GTPase regulator activity
1.28	3.99e-02	GO:0003702	RNA polymerase II transcription factor activity
1.21	4.17e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.31	4.41e-02	GO:0019901	protein kinase binding
1.11	4.91e-02	GO:0030554	adenyl nucleotide binding
1.14	4.94e-02	GO:0030234	enzyme regulator activity