Motif ID: SPI1.p2

Z-value: 3.251


Transcription factors associated with SPI1.p2:

Gene SymbolEntrez IDGene Name
SPI1 6688 spleen focus forming virus (SFFV) proviral integration oncogene spi1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPI1chr11_-_473566500.543.7e-02Click!


Activity profile for motif SPI1.p2.

activity profile for motif SPI1.p2


Sorted Z-values histogram for motif SPI1.p2

Sorted Z-values for motif SPI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPI1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_35586950 5.684 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chrX_-_47374187 4.842 NM_001145252
CFP
complement factor properdin
chr1_+_159899528 4.539 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr12_+_48443232 4.203 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr16_-_87570716 3.690 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chrX_-_47374647 3.319 NM_002621
CFP
complement factor properdin
chr1_+_159817752 3.119 NM_201563
FCGR2C
Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr10_+_49562866 3.005 WDFY4
WDFY family member 4
chr6_+_31690957 2.999 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr11_+_65164767 2.956 SIPA1
signal-induced proliferation-associated 1
chr6_+_31661934 2.927 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr6_+_31662454 2.809 NM_205837
LST1
leukocyte specific transcript 1
chr2_+_108604111 2.778 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr19_-_10311262 2.636 NM_002162
ICAM3
intercellular adhesion molecule 3
chr17_+_53625084 2.591 NM_000502
EPX
eosinophil peroxidase
chr11_+_63864263 2.547 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr14_+_20319049 2.536 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr19_-_46504831 2.520


chr7_+_106292932 2.495 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr16_+_28413421 2.424 NM_018690
APOBR
apolipoprotein B receptor
chr16_-_29664765 2.363 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr12_+_50592379 2.337 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr7_+_106292975 2.316 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr9_-_129707392 2.258 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_56134077 2.241 NM_153837
GPR114
G protein-coupled receptor 114
chr17_-_40843530 2.197 ARHGAP27
Rho GTPase activating protein 27
chr16_+_56134037 2.180 GPR114
G protein-coupled receptor 114
chr19_-_55104875 2.147 NUP62
nucleoporin 62kDa
chr19_-_7672978 2.138 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr17_+_31455332 2.092 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr3_-_180467483 1.987 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr6_+_31648071 1.919 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr12_+_55018925 1.891 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr19_-_43608641 1.885 NM_001146202
NM_001146203
NM_001146204
NM_001146205
NM_001146206
NM_001146207
NM_170604
RASGRP4






RAS guanyl releasing protein 4






chr12_+_53241365 1.834 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr9_+_263025 1.828 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr19_-_13074973 1.788 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr19_+_59866217 1.773 LILRB4
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
chr22_-_16080265 1.747 CECR1
cat eye syndrome chromosome region, candidate 1
chr17_-_43288137 1.742 NM_199262
SP6
Sp6 transcription factor
chr1_-_21375939 1.712 NM_001198801
NM_001198802
EIF4G3

eukaryotic translation initiation factor 4 gamma, 3

chr1_-_156078115 1.660 NM_005894
CD5L
CD5 molecule-like
chr6_+_31647854 1.643 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr7_+_101715110 1.643 NM_020979
SH2B2
SH2B adaptor protein 2
chr19_+_14412080 1.641 NM_213560
PKN1
protein kinase N1
chr19_+_14412052 1.638 PKN1
protein kinase N1
chr8_+_145158432 1.635 NM_001134374
NM_198572
SPATC1

spermatogenesis and centriole associated 1

chr22_+_35639564 1.625 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr12_-_12310969 1.604 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr19_+_40895669 1.600 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr1_+_26517032 1.568 CD52
CD52 molecule
chr1_+_154351200 1.549 LMNA
lamin A/C
chr12_-_56422120 1.505 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr5_+_148711419 1.478 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr22_-_35970230 1.475 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr8_+_21956335 1.463 NM_003867
FGF17
fibroblast growth factor 17
chr17_+_31562577 1.459 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr3_+_108724472 1.454 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr19_+_14412087 1.437 PKN1
protein kinase N1
chr12_-_50004102 1.432 BIN2
bridging integrator 2
chr7_+_101715137 1.432 SH2B2
SH2B adaptor protein 2
chr12_+_48443588 1.425 TMBIM6
transmembrane BAX inhibitor motif containing 6
chr15_-_76313896 1.419 NM_015162
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr11_-_18226743 1.398 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr1_+_36462625 1.397 THRAP3
thyroid hormone receptor associated protein 3
chr11_+_47386707 1.395 SLC39A13
solute carrier family 39 (zinc transporter), member 13
chr20_-_44612619 1.394 NM_080721
C20orf123
chromosome 20 open reading frame 123
chrX_+_41191630 1.367 NM_022567
NYX
nyctalopin
chr11_+_47386621 1.354 NM_001128225
NM_152264
SLC39A13

solute carrier family 39 (zinc transporter), member 13

chr1_+_26517045 1.353 CD52
CD52 molecule
chr19_+_60109319 1.352 NM_001145457
NM_001145458
NM_004829
NCR1


natural cytotoxicity triggering receptor 1


chr12_-_50004208 1.352 BIN2
bridging integrator 2
chr16_-_87297525 1.349 NM_001171816
RNF166
ring finger protein 166
chr1_-_205186330 1.334 NM_002644
PIGR
polymeric immunoglobulin receptor
chr3_-_113334657 1.332 NM_001190259
NM_001190260
NM_152785
GCET2


germinal center expressed transcript 2


chr4_+_71986927 1.330 NM_173468
MOBKL1A
MOB1, Mps One Binder kinase activator-like 1A (yeast)
chr12_-_50004172 1.322 NM_016293
BIN2
bridging integrator 2
chr12_-_56159631 1.319 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr12_-_53071285 1.319 NM_001130967
NM_001130968
ZNF385A

zinc finger protein 385A

chr6_-_32299757 1.313 NM_004557
NOTCH4
notch 4
chr9_-_99740243 1.306 NM_197978
HEMGN
hemogen
chr19_-_60611136 1.289 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr22_-_35970133 1.284 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr9_-_73573121 1.275 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr19_+_59776293 1.267 LILRA2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
chr19_-_13074669 1.266 LYL1
lymphoblastic leukemia derived sequence 1
chr12_-_53664722 1.258 NM_001136030
KIAA0748
KIAA0748
chr1_+_207995999 1.251 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr6_+_31691745 1.236 NM_032955
AIF1
allograft inflammatory factor 1
chr17_+_31664143 1.235 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr11_+_72658586 1.230 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr4_+_91035025 1.211 NM_007351
MMRN1
multimerin 1
chr5_-_176869943 1.207 NM_001144875
NM_001144876
DOK3

docking protein 3

chr5_-_176258920 1.207 NM_002115
HK3
hexokinase 3 (white cell)
chr12_-_56159895 1.200 NM_032496
ARHGAP9
Rho GTPase activating protein 9
chr1_-_145712107 1.197 NM_005266
GJA5
gap junction protein, alpha 5, 40kDa
chr7_+_149895390 1.195 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr22_+_42900168 1.194 NM_001137605
PARVG
parvin, gamma
chrX_-_44945025 1.193 NM_024689
NM_176819
CXorf36

chromosome X open reading frame 36

chr2_+_66519949 1.188 MEIS1
Meis homeobox 1
chr17_-_31441390 1.183 NM_002983
CCL3
chemokine (C-C motif) ligand 3
chr12_-_53065758 1.182 ZNF385A
zinc finger protein 385A
chr6_+_31651319 1.180 NM_000594
TNF
tumor necrosis factor
chr6_-_88911708 1.176 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr19_-_6432765 1.169 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr19_-_17349096 1.167 NM_031310
PLVAP
plasmalemma vesicle associated protein
chr2_+_169637255 1.164 NM_001142270
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr7_-_100077072 1.158 NM_003227
TFR2
transferrin receptor 2
chr7_+_73826244 1.157 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr6_-_154719560 1.156 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr7_+_128367961 1.153 NM_001098627
IRF5
interferon regulatory factor 5
chr8_+_126511739 1.146 NM_025195
TRIB1
tribbles homolog 1 (Drosophila)
chr1_-_26517342 1.141 NM_145345
UBXN11
UBX domain protein 11
chrX_-_135577102 1.135 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_-_169657395 1.135 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_156526182 1.133 NM_001765
CD1C
CD1c molecule
chr11_-_64403712 1.132 EHD1
EH-domain containing 1
chrX_+_48427137 1.128 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr11_+_65164167 1.127 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr12_-_53661888 1.124 NM_001098815
KIAA0748
KIAA0748
chr11_+_2877486 1.120 NM_183233
SLC22A18
solute carrier family 22, member 18
chr7_-_132371208 1.115 EEF1G
eukaryotic translation elongation factor 1 gamma
chr6_-_31658044 1.109 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chrX_+_48427103 1.105 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr18_-_50004770 1.102 MBD2
methyl-CpG binding domain protein 2
chr15_+_36332258 1.100 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr17_+_44642587 1.097 NM_001135186
NM_016428
ABI3

ABI family, member 3

chr19_-_8548232 1.093 MYO1F
myosin IF
chr7_+_18296569 1.092 HDAC9
histone deacetylase 9
chrX_-_134883798 1.091 NM_173470
MMGT1
membrane magnesium transporter 1
chr8_-_116749382 1.091 TRPS1
trichorhinophalangeal syndrome I
chr11_+_66927955 1.087 TBC1D10C
TBC1 domain family, member 10C
chr16_+_48865521 1.087 ADCY7
adenylate cyclase 7
chr17_-_55824083 1.086 USP32
ubiquitin specific peptidase 32
chr10_+_17312654 1.079 VIM
vimentin
chr5_+_140871107 1.071


chr17_-_59363352 1.055 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr19_+_40465249 1.050 NM_021175
HAMP
hepcidin antimicrobial peptide
chr22_+_23333610 1.050 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr3_-_15349086 1.043 NM_004844
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr7_-_3049872 1.043 NM_032415
CARD11
caspase recruitment domain family, member 11
chr1_-_180908639 1.036 NM_001102450
NM_033345
RGS8

regulator of G-protein signaling 8

chr7_+_149779011 1.033 GIMAP8
GTPase, IMAP family member 8
chr1_+_154351162 1.028 LMNA
lamin A/C
chr16_+_31274020 1.027 ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr5_-_169657312 1.020 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169657360 1.018 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_+_46323575 1.012 DGKZ
diacylglycerol kinase, zeta
chr11_+_59902530 1.010 NM_021201
NM_206938
NM_206939
NM_206940
MS4A7



membrane-spanning 4-domains, subfamily A, member 7



chr7_+_106293112 1.010 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_122862447 1.009 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr22_+_23153529 1.007 NM_000675
ADORA2A
adenosine A2a receptor
chr19_+_54068373 0.997 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr11_+_118269310 0.996 NM_032966
CXCR5
chemokine (C-X-C motif) receptor 5
chr11_+_46323495 0.993 DGKZ
diacylglycerol kinase, zeta
chr6_+_144649142 0.991 UTRN
utrophin
chr20_-_1548589 0.987 NM_001083910
NM_001135844
NM_006065
SIRPB1


signal-regulatory protein beta 1


chr19_-_15436333 0.986 NM_022904
RASAL3
RAS protein activator like 3
chr12_-_8656705 0.982 NM_020661
AICDA
activation-induced cytidine deaminase
chr11_-_117640078 0.977


chr5_-_169657192 0.977 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr2_-_231498184 0.972 NM_005683
GPR55
G protein-coupled receptor 55
chr10_-_49483002 0.971 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr6_+_108988797 0.970 FOXO3
forkhead box O3
chr3_-_120861959 0.968 NM_022135
POPDC2
popeye domain containing 2
chr1_+_78126787 0.968 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr12_+_52103905 0.966 NM_001164690
NM_001164691
NM_020547
AMHR2


anti-Mullerian hormone receptor, type II


chr16_+_80086454 0.965 NM_030629
CMIP
c-Maf-inducing protein
chr1_+_36462583 0.964 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr3_-_122862391 0.960 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_+_51474558 0.958 RNF11
ring finger protein 11
chr19_-_56726704 0.952 NM_001177547
NM_001177548
NM_001177549
NM_001245
NM_198845
NM_198846
SIGLEC6





sialic acid binding Ig-like lectin 6





chr5_-_176869440 0.949 DOK3
docking protein 3
chr2_-_168812132 0.947 NM_013233
STK39
serine threonine kinase 39
chr19_+_59865935 0.944 NM_001081438
NM_006847
LILRB4

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4

chr5_+_159589014 0.940 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr17_+_35532994 0.939 MSL1
male-specific lethal 1 homolog (Drosophila)
chr10_-_71002998 0.932 NM_020999
NEUROG3
neurogenin 3
chr7_+_150065376 0.927 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr22_+_42908612 0.919 PARVG
parvin, gamma
chr6_+_37081387 0.917 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr1_-_27113018 0.915 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr16_+_31273969 0.912 NM_000887
ITGAX
integrin, alpha X (complement component 3 receptor 4 subunit)
chr7_-_81237162 0.910 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr1_+_111544469 0.908


chr11_-_76059435 0.908 NM_001128922
LRRC32
leucine rich repeat containing 32
chr5_-_157218555 0.908 NM_001195555
NM_001195556
NM_014666
CLINT1


clathrin interactor 1


chr1_-_158815895 0.907 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr1_+_156590109 0.901 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chr1_+_43539239 0.898 NM_005424
TIE1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_+_241213334 0.896 NM_005301
GPR35
G protein-coupled receptor 35
chr11_+_1818007 0.890 NM_001145841
TNNI2
troponin I type 2 (skeletal, fast)
chr3_-_187025501 0.889 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr1_-_205161821 0.889 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr10_+_99884370 0.888 NM_014472
C10orf28
chromosome 10 open reading frame 28
chr3_+_3056307 0.884 NM_175612
CNTN4
contactin 4
chr16_-_30301634 0.883 NM_052838
SEPT1
septin 1
chr17_-_35975227 0.882 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr1_+_157441824 0.879 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr1_+_51474502 0.876 RNF11
ring finger protein 11

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 6.15e-17 GO:0050794 regulation of cellular process
1.12 1.29e-15 GO:0065007 biological regulation
1.12 4.92e-15 GO:0050789 regulation of biological process
1.28 7.52e-13 GO:0048583 regulation of response to stimulus
1.21 7.83e-11 GO:0048518 positive regulation of biological process
1.32 4.04e-10 GO:0002376 immune system process
1.30 4.93e-10 GO:0009966 regulation of signal transduction
1.23 1.13e-09 GO:0048523 negative regulation of cellular process
1.22 2.46e-09 GO:0048519 negative regulation of biological process
1.15 2.56e-09 GO:0044260 cellular macromolecule metabolic process
1.21 2.69e-09 GO:0048522 positive regulation of cellular process
1.06 3.91e-09 GO:0009987 cellular process
1.16 3.86e-08 GO:0031323 regulation of cellular metabolic process
1.25 6.01e-08 GO:0023051 regulation of signaling
1.15 6.85e-08 GO:0019222 regulation of metabolic process
1.46 2.10e-07 GO:0001775 cell activation
1.64 4.66e-07 GO:0045321 leukocyte activation
1.14 6.78e-07 GO:0051716 cellular response to stimulus
1.22 7.12e-07 GO:0006464 protein modification process
1.16 7.36e-07 GO:0016043 cellular component organization
1.12 8.20e-07 GO:0043170 macromolecule metabolic process
1.15 1.05e-06 GO:0080090 regulation of primary metabolic process
1.15 2.62e-06 GO:0007165 signal transduction
1.15 3.60e-06 GO:0071840 cellular component organization or biogenesis
1.29 4.74e-06 GO:0043067 regulation of programmed cell death
1.15 1.09e-05 GO:0060255 regulation of macromolecule metabolic process
1.28 1.15e-05 GO:0042981 regulation of apoptosis
1.28 1.32e-05 GO:0010941 regulation of cell death
1.13 1.96e-05 GO:0023052 signaling
1.26 2.23e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.32 2.28e-05 GO:0046907 intracellular transport
1.17 3.23e-05 GO:0044267 cellular protein metabolic process
1.19 7.09e-05 GO:0043412 macromolecule modification
1.24 8.74e-05 GO:0009893 positive regulation of metabolic process
1.24 1.06e-04 GO:0031325 positive regulation of cellular metabolic process
1.21 1.16e-04 GO:0006996 organelle organization
1.44 1.17e-04 GO:0051056 regulation of small GTPase mediated signal transduction
1.15 1.48e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.40 2.16e-04 GO:0002684 positive regulation of immune system process
1.60 2.25e-04 GO:0046649 lymphocyte activation
1.31 2.45e-04 GO:0002682 regulation of immune system process
1.15 2.52e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.52 4.53e-04 GO:0030097 hemopoiesis
1.80 1.03e-03 GO:0030098 lymphocyte differentiation
2.14 1.10e-03 GO:0002263 cell activation involved in immune response
2.14 1.10e-03 GO:0002366 leukocyte activation involved in immune response
1.63 1.26e-03 GO:0050900 leukocyte migration
1.27 1.33e-03 GO:0009891 positive regulation of biosynthetic process
1.14 1.33e-03 GO:0071842 cellular component organization at cellular level
1.46 1.36e-03 GO:0002520 immune system development
1.24 1.47e-03 GO:0006793 phosphorus metabolic process
1.24 1.47e-03 GO:0006796 phosphate metabolic process
1.15 1.58e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.37 1.81e-03 GO:0050776 regulation of immune response
1.28 1.87e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.33 2.19e-03 GO:0006928 cellular component movement
1.31 2.45e-03 GO:0051726 regulation of cell cycle
1.23 2.47e-03 GO:0051649 establishment of localization in cell
1.28 2.62e-03 GO:0006955 immune response
1.46 2.90e-03 GO:0048534 hemopoietic or lymphoid organ development
1.19 3.09e-03 GO:0065009 regulation of molecular function
1.26 3.18e-03 GO:0040011 locomotion
1.88 3.58e-03 GO:0007173 epidermal growth factor receptor signaling pathway
1.18 3.83e-03 GO:0016070 RNA metabolic process
1.66 4.12e-03 GO:0032318 regulation of Ras GTPase activity
1.26 4.82e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.33 4.91e-03 GO:0007599 hemostasis
1.20 5.39e-03 GO:0035556 intracellular signal transduction
1.24 5.52e-03 GO:0042127 regulation of cell proliferation
1.14 5.61e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.13 6.01e-03 GO:0009889 regulation of biosynthetic process
1.20 6.75e-03 GO:0051641 cellular localization
1.33 7.51e-03 GO:0007596 blood coagulation
1.33 7.51e-03 GO:0050817 coagulation
1.13 7.73e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.26 7.89e-03 GO:0048584 positive regulation of response to stimulus
1.14 8.38e-03 GO:0006950 response to stress
1.08 8.50e-03 GO:0044237 cellular metabolic process
1.13 9.12e-03 GO:0031326 regulation of cellular biosynthetic process
1.08 1.01e-02 GO:0044238 primary metabolic process
1.30 1.03e-02 GO:0042060 wound healing
1.46 1.08e-02 GO:0002694 regulation of leukocyte activation
1.58 1.26e-02 GO:0043087 regulation of GTPase activity
1.13 1.36e-02 GO:0010468 regulation of gene expression
1.34 1.48e-02 GO:0043069 negative regulation of programmed cell death
1.35 1.49e-02 GO:0007243 intracellular protein kinase cascade
1.35 1.49e-02 GO:0023014 signal transduction via phosphorylation event
1.45 1.50e-02 GO:0050865 regulation of cell activation
1.39 1.53e-02 GO:0051098 regulation of binding
1.45 1.55e-02 GO:0046578 regulation of Ras protein signal transduction
1.57 1.74e-02 GO:0033124 regulation of GTP catabolic process
1.43 1.96e-02 GO:0051101 regulation of DNA binding
1.34 2.31e-02 GO:0016477 cell migration
2.24 2.39e-02 GO:0002285 lymphocyte activation involved in immune response
2.10 2.44e-02 GO:0045727 positive regulation of translation
1.93 2.94e-02 GO:0060326 cell chemotaxis
1.23 3.01e-02 GO:0009611 response to wounding
1.33 3.07e-02 GO:0043066 negative regulation of apoptosis
1.30 3.38e-02 GO:0043068 positive regulation of programmed cell death
1.46 3.42e-02 GO:0051249 regulation of lymphocyte activation
1.12 3.66e-02 GO:0019538 protein metabolic process
1.23 3.82e-02 GO:0051128 regulation of cellular component organization
1.25 4.54e-02 GO:0006468 protein phosphorylation
1.21 4.55e-02 GO:0009605 response to external stimulus
1.31 4.65e-02 GO:0048870 cell motility
1.31 4.65e-02 GO:0051674 localization of cell
1.21 4.79e-02 GO:0032268 regulation of cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.07 5.54e-16 GO:0005622 intracellular
1.07 1.52e-14 GO:0044424 intracellular part
1.13 1.13e-11 GO:0005634 nucleus
1.08 4.53e-11 GO:0043226 organelle
1.08 5.67e-11 GO:0043229 intracellular organelle
1.09 6.79e-11 GO:0043227 membrane-bounded organelle
1.09 1.14e-10 GO:0043231 intracellular membrane-bounded organelle
1.03 1.63e-09 GO:0005623 cell
1.03 2.09e-09 GO:0044464 cell part
1.08 8.87e-09 GO:0005737 cytoplasm
1.20 1.86e-07 GO:0005829 cytosol
1.19 4.15e-07 GO:0044428 nuclear part
1.24 4.09e-06 GO:0005654 nucleoplasm
1.10 6.41e-06 GO:0044422 organelle part
1.19 7.79e-06 GO:0031981 nuclear lumen
1.10 8.28e-06 GO:0044446 intracellular organelle part
1.09 7.27e-05 GO:0044444 cytoplasmic part
1.29 1.01e-04 GO:0044451 nucleoplasm part
1.13 3.05e-04 GO:0043234 protein complex
1.14 1.31e-03 GO:0043233 organelle lumen
1.11 2.49e-03 GO:0032991 macromolecular complex
1.14 2.57e-03 GO:0031974 membrane-enclosed lumen
1.14 4.88e-03 GO:0070013 intracellular organelle lumen
1.34 1.35e-02 GO:0048471 perinuclear region of cytoplasm

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 3.47e-33 GO:0005515 protein binding
1.06 1.29e-11 GO:0005488 binding
1.44 3.81e-07 GO:0060589 nucleoside-triphosphatase regulator activity
1.59 6.28e-07 GO:0005096 GTPase activator activity
1.43 8.74e-07 GO:0030695 GTPase regulator activity
1.42 3.09e-05 GO:0008047 enzyme activator activity
1.25 1.06e-04 GO:0030528 transcription regulator activity
1.36 7.39e-04 GO:0019904 protein domain specific binding
1.75 1.14e-03 GO:0005099 Ras GTPase activator activity
1.27 1.18e-03 GO:0019899 enzyme binding
1.23 1.32e-03 GO:0030234 enzyme regulator activity
1.41 1.53e-03 GO:0016564 transcription repressor activity
1.41 3.16e-03 GO:0005083 small GTPase regulator activity
1.76 3.87e-03 GO:0035257 nuclear hormone receptor binding
1.35 7.74e-03 GO:0003712 transcription cofactor activity
1.34 9.32e-03 GO:0000988 protein binding transcription factor activity
1.34 9.32e-03 GO:0000989 transcription factor binding transcription factor activity
1.67 1.19e-02 GO:0051427 hormone receptor binding
1.43 2.10e-02 GO:0003713 transcription coactivator activity
1.39 2.78e-02 GO:0032403 protein complex binding
1.40 3.33e-02 GO:0019900 kinase binding
1.49 3.82e-02 GO:0004721 phosphoprotein phosphatase activity