Motif ID: SPZ1.p2

Z-value: 1.269


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_796515450.273.2e-01Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_52980914 0.866 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr1_+_199130571 0.854 NM_001142569
 C1orf106
chromosome 1 open reading frame 106
chr17_-_36469869 0.797 NM_001165252
 LOC730755
keratin associated protein 2-4-like
chr19_+_45973139 0.745 NM_006533
 MIA
melanoma inhibitory activity
chr3_+_214668 0.738


chr16_+_29819647 0.724 NM_181718
 ASPHD1
aspartate beta-hydroxylase domain containing 1
chr10_-_105411339 0.716 SH3PXD2A
SH3 and PX domains 2A
chr17_-_74231266 0.673 CYTH1
cytohesin 1
chr17_-_24973940 0.662 CORO6
coronin 6
chr17_-_36475652 0.643 NM_033184
 KRTAP2-4
keratin associated protein 2-4
chr11_+_12987455 0.634 NM_001080521
 RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr6_-_41230003 0.608 NM_178174
 TREML1
triggering receptor expressed on myeloid cells-like 1
chr1_-_151855413 0.608 NM_020672
 S100A14
S100 calcium binding protein A14
chr6_-_119712596 0.590 NM_005907
 MAN1A1
mannosidase, alpha, class 1A, member 1
chr3_-_62835601 0.584


chr17_-_77824849 0.580 NM_001893
NM_139062
 CSNK1D

casein kinase 1, delta

chr11_-_110755366 0.565 NM_006235
 POU2AF1
POU class 2 associating factor 1
chr12_-_52980984 0.565 NM_001136023
 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr16_-_66535457 0.560 NM_000229
 LCAT
lecithin-cholesterol acyltransferase
chr17_+_33761234 0.558 NM_014598
 SOCS7
suppressor of cytokine signaling 7

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 94 entries
enrichment   p-value GO term description
2.50 8.84e-03 GO:0045995 regulation of embryonic development
2.21 2.46e-03 GO:2000027 regulation of organ morphogenesis
1.93 1.46e-04 GO:0045165 cell fate commitment
1.74 2.18e-03 GO:0048732 gland development
1.71 1.32e-02 GO:0030900 forebrain development
1.70 2.51e-02 GO:0030155 regulation of cell adhesion
1.66 2.04e-07 GO:0007409 axonogenesis
1.65 4.12e-09 GO:0000904 cell morphogenesis involved in differentiation
1.65 1.02e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
1.65 1.04e-07 GO:0048812 neuron projection morphogenesis
1.62 9.83e-03 GO:0003002 regionalization
1.59 4.01e-03 GO:0007423 sensory organ development
1.58 6.33e-07 GO:0048858 cell projection morphogenesis
1.58 7.35e-04 GO:0007411 axon guidance
1.57 4.71e-10 GO:0030182 neuron differentiation
1.57 1.33e-06 GO:0032990 cell part morphogenesis
1.57 1.67e-06 GO:0031175 neuron projection development
1.56 2.03e-08 GO:0032989 cellular component morphogenesis
1.56 2.26e-07 GO:0048666 neuron development
1.56 4.56e-02 GO:0050767 regulation of neurogenesis

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.88 1.43e-03 GO:0001725 stress fiber
2.86 2.60e-04 GO:0042641 actomyosin
2.69 5.89e-03 GO:0032432 actin filament bundle
1.71 1.67e-02 GO:0043235 receptor complex
1.48 1.04e-06 GO:0030054 cell junction
1.46 1.65e-02 GO:0005578 proteinaceous extracellular matrix
1.43 5.85e-03 GO:0045202 synapse
1.40 2.75e-02 GO:0031012 extracellular matrix
1.26 3.03e-08 GO:0044459 plasma membrane part
1.26 3.52e-02 GO:0042995 cell projection
1.17 2.56e-07 GO:0071944 cell periphery
1.17 3.17e-07 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.53 1.18e-03 GO:0016563 transcription activator activity
1.53 8.60e-03 GO:0005261 cation channel activity
1.39 1.43e-04 GO:0043565 sequence-specific DNA binding
1.38 4.07e-03 GO:0008324 cation transmembrane transporter activity
1.38 5.12e-03 GO:0008092 cytoskeletal protein binding
1.36 5.40e-06 GO:0001071 nucleic acid binding transcription factor activity
1.36 5.40e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.30 1.98e-02 GO:0015075 ion transmembrane transporter activity
1.29 1.43e-03 GO:0030528 transcription regulator activity
1.11 1.19e-06 GO:0005515 protein binding