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Motif ID: SRF.p3

Z-value: 1.800

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_73973640	4.193		ACTG2	actin, gamma 2, smooth muscle, enteric
chr2_+_73973600	4.188	NM_001615	ACTG2	actin, gamma 2, smooth muscle, enteric
chr15_-_32875040	3.583	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr20_+_34603290	3.580	NM_006097 NM_181526	MYL9	myosin, light chain 9, regulatory
chr20_+_34603311	3.243		MYL9	myosin, light chain 9, regulatory
chr5_+_137829065	2.975		EGR1	early growth response 1
chr1_-_16217025	2.874		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr3_+_189413414	2.757	NM_005578	LPP	LIM domain containing preferred translocation partner in lipoma
chr18_-_3209846	2.755		MYOM1	myomesin 1, 185kDa
chr1_-_11830328	2.503	NM_006172	NPPA	natriuretic peptide A
chr2_+_218992053	2.378	NM_007127	VIL1	villin 1
chr19_-_50517971	2.229		CKM	creatine kinase, muscle
chr3_-_46879883	2.070	NM_000258	MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow
chr15_-_63147350	1.980	NM_016563	RASL12	RAS-like, family 12
chr16_-_11282595	1.907	NM_002761	PRM1	protamine 1
chr10_-_90702490	1.860	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr5_+_137829077	1.749	NM_001964	EGR1	early growth response 1
chr17_+_30498948	1.633	NM_001033576 NM_173167	UNC45B	unc-45 homolog B (C. elegans)
chr3_-_71376919	1.592		FOXP1	forkhead box P1
chr3_+_150675117	1.578	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr16_-_66535457	1.516	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr10_+_88418147	1.479	NM_001171610	LDB3	LIM domain binding 3
chr10_+_88418243	1.457	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr1_-_240228987	1.451	NM_001004343	MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma
chr6_-_109882116	1.441		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr11_-_16387001	1.402	NM_001145811	SOX6	SRY (sex determining region Y)-box 6
chr2_+_88148413	1.377	NM_198274	SMYD1	SET and MYND domain containing 1
chr18_-_3209986	1.377	NM_003803 NM_019856	MYOM1	myomesin 1, 185kDa
chr2_-_225086564	1.376		CUL3	cullin 3
chr3_-_124821868	1.285		MYLK	myosin light chain kinase
chr19_-_50518072	1.268	NM_001824	CKM	creatine kinase, muscle
chr3_-_187124290	1.229		TRA2B	transformer 2 beta homolog (Drosophila)
chrX_-_11194015	1.198	NM_013423	ARHGAP6	Rho GTPase activating protein 6
chr3_-_153470022	1.195		LOC401093	hypothetical LOC401093
chr2_+_42128521	1.175	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr19_+_50109416	1.153		APOC1	apolipoprotein C-I
chr1_-_227636462	1.103	NM_001100	ACTA1	actin, alpha 1, skeletal muscle
chr6_-_123999640	1.086	NM_006073	TRDN	triadin
chr17_+_3326045	1.079	NM_000049	ASPA	aspartoacylase
chr3_-_124822113	0.991	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr15_-_63147228	0.983		RASL12	RAS-like, family 12
chr4_+_24406182	0.967	NM_003102	SOD3	superoxide dismutase 3, extracellular
chr1_-_31618405	0.959	NM_004102	FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr2_+_100545827	0.957	NM_024065	PDCL3	phosducin-like 3
chr10_+_112247614	0.900	NM_004419	DUSP5	dual specificity phosphatase 5
chr19_+_2427122	0.876	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr19_+_59064795	0.874		MYADM	myeloid-associated differentiation marker
chr12_-_23995220	0.852		SOX5	SRY (sex determining region Y)-box 5
chr3_+_150675169	0.833		TM4SF4	transmembrane 4 L six family member 4
chr17_+_38256710	0.824	NM_003734	AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr14_-_93512818	0.823		ASB2	ankyrin repeat and SOCS box containing 2
chr4_+_14985272	0.784	NM_001135171	C1QTNF7	C1q and tumor necrosis factor related protein 7
chr6_+_151602787	0.738	NM_005100	AKAP12	A kinase (PRKA) anchor protein 12
chr1_+_15957832	0.728	NM_017556	FBLIM1	filamin binding LIM protein 1
chr1_-_20178680	0.717	NM_001161729	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)
chr17_+_29707583	0.709	NM_005408	CCL13	chemokine (C-C motif) ligand 13
chr10_+_123912930	0.698		TACC2	transforming, acidic coiled-coil containing protein 2
chr20_-_33783409	0.698		RBM39	RNA binding motif protein 39
chr2_-_105381855	0.697	NM_001039492 NM_001450 NM_201555	FHL2	four and a half LIM domains 2
chr20_-_33706532	0.696		RBM12	RNA binding motif protein 12
chr1_-_152431175	0.691	NM_152263	TPM3	tropomyosin 3
chr1_+_165865953	0.681	NM_052862	RCSD1	RCSD domain containing 1
chr6_+_144654565	0.669	NM_007124	UTRN	utrophin
chr2_-_105421661	0.661	NM_201557	FHL2	four and a half LIM domains 2
chr6_-_29635680	0.650	NM_006398	UBD	ubiquitin D
chr6_+_158322875	0.637	NM_003898	SYNJ2	synaptojanin 2
chr14_-_93512647	0.635		ASB2	ankyrin repeat and SOCS box containing 2
chr11_+_62189354	0.622	NM_001043229	METTL12	methyltransferase like 12
chr1_+_165866127	0.600		RCSD1	RCSD domain containing 1
chr11_+_116575249	0.585	NM_001001522 NM_003186	TAGLN	transgelin
chr8_-_22606653	0.578	NM_004430	EGR3	early growth response 3
chr19_+_50663089	0.570	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr6_+_44322764	0.555	NM_007355	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr2_+_46560207	0.553	NM_001145051	LOC388946	transmembrane protein ENSP00000343375
chr20_-_33198721	0.548	NM_001145025 NM_018217	EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr11_-_57038891	0.540	NM_001198810	SLC43A1	solute carrier family 43, member 1
chr12_-_23995109	0.537		SOX5	SRY (sex determining region Y)-box 5
chr12_+_50731457	0.536	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr17_-_69869552	0.533	NM_001080466	BTBD17	BTB (POZ) domain containing 17
chr2_-_73373956	0.531	NM_001965	EGR4	early growth response 4
chr17_-_38385511	0.525	NM_025267	AARSD1	alanyl-tRNA synthetase domain containing 1
chr11_+_59564323	0.503	NM_173801	PLAC1L	placenta-specific 1-like
chr6_-_16869579	0.501	NM_000332 NM_001128164	ATXN1	ataxin 1
chr18_-_42804291	0.496	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr17_+_29636799	0.472	NM_002986	CCL11	chemokine (C-C motif) ligand 11
chr16_+_30015899	0.468
chr11_-_75599433	0.467		WNT11	wingless-type MMTV integration site family, member 11
chr10_+_114033403	0.459	NM_058222	TECTB	tectorin beta
chr2_-_21120420	0.449	NM_000384	APOB	apolipoprotein B (including Ag(x) antigen)
chr20_-_61728866	0.446		GMEB2	glucocorticoid modulatory element binding protein 2
chr17_+_16259636	0.442		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr11_-_2118743	0.441		IGF2	insulin-like growth factor 2 (somatomedin A)
chr3_-_158704056	0.440	NM_001167915 NM_001167916	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr18_-_42804531	0.425	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr6_-_29635456	0.424		UBD	ubiquitin D
chr11_+_66070949	0.410	NM_001104	ACTN3	actinin, alpha 3
chr7_-_107430566	0.406	NM_002291	LAMB1	laminin, beta 1
chr5_-_178983241	0.401		HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)
chr19_-_40939756	0.399	NM_144617	HSPB6	heat shock protein, alpha-crystallin-related, B6
chr6_-_25834733	0.398	NM_170745	HIST1H2AA	histone cluster 1, H2aa
chr16_+_31105579	0.390
chr17_+_16259573	0.388	NM_016113	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr5_+_60663842	0.388	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr7_+_111908143	0.385	NM_001134468 NM_182597	C7orf53	chromosome 7 open reading frame 53
chr19_-_52666886	0.383		SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2
chr11_-_65424385	0.377		FOSL1	FOS-like antigen 1
chr12_+_48784057	0.376	NM_005276	GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)
chr20_-_21442663	0.375	NM_002509	NKX2-2	NK2 homeobox 2
chr17_-_36456949	0.366	NM_001123387	KRTAP2-1	keratin associated protein 2-1
chr14_-_54438913	0.358	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr12_-_90029672	0.357	NM_002345	LUM	lumican
chr19_+_59064471	0.357	NM_001020821 NM_001020818	MYADM	myeloid-associated differentiation marker
chr11_+_65945050	0.353	NM_178864	NPAS4	neuronal PAS domain protein 4
chr6_+_43247179	0.352		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr10_+_80777234	0.349		PPIF	peptidylprolyl isomerase F
chr6_+_158322904	0.344		SYNJ2	synaptojanin 2
chr5_+_88220846	0.332
chr17_-_34603577	0.326		CACNB1	calcium channel, voltage-dependent, beta 1 subunit
chr18_-_42810446	0.324	NM_145653	TCEB3C	transcription elongation factor B polypeptide 3C (elongin A3)
chr2_-_128149112	0.323	NM_001136037 NM_001161403	LIMS2	LIM and senescent cell antigen-like domains 2
chr7_-_5536783	0.315		ACTB	actin, beta
chr11_+_46339691	0.314	NM_001105540	DGKZ	diacylglycerol kinase, zeta
chr6_+_44322831	0.312		HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1
chr10_+_80777199	0.309	NM_005729	PPIF	peptidylprolyl isomerase F
chr17_-_77094426	0.308		ACTG1	actin, gamma 1
chr17_-_77094375	0.299	NM_001614	ACTG1	actin, gamma 1
chr22_+_24468110	0.292	NM_032608	MYO18B	myosin XVIIIB
chr17_+_16259812	0.290		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr17_-_77386156	0.288		DYSFIP1	dysferlin interacting protein 1
chr14_+_74815233	0.288	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr15_-_53369261	0.286	NM_183235	RAB27A	RAB27A, member RAS oncogene family
chr5_+_6799100	0.284	NM_001171806	PAPD7	PAP associated domain containing 7
chr4_-_88669625	0.282	NM_001128310 NM_004684	SPARCL1	SPARC-like 1 (hevin)
chr6_+_43246897	0.282	NM_003131	SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr17_-_23721351	0.280		VTN	vitronectin
chr17_-_23721420	0.275		VTN	vitronectin
chr20_+_4650499	0.271	NM_012409	PRND	prion protein 2 (dublet)
chr11_-_65424434	0.263		FOSL1	FOS-like antigen 1
chr6_+_43247168	0.256		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr2_+_107969410	0.252	NM_021815	SLC5A7	solute carrier family 5 (choline transporter), member 7
chr10_+_6226909	0.250		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr20_+_60558104	0.250	NM_178463	C20orf166	chromosome 20 open reading frame 166
chr14_+_104338423	0.248		ZBTB42	zinc finger and BTB domain containing 42
chr12_-_55730125	0.247	NM_005379	MYO1A	myosin IA
chr3_-_158695832	0.243	NM_001167917	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)
chr17_-_46296376	0.243	NM_005749	TOB1	transducer of ERBB2, 1
chr2_+_55312542	0.240	NM_001135592	RPS27A	ribosomal protein S27a
chr1_-_120737466	0.240	NM_001004340 NM_001017986	FCGR1A FCGR1B	Fc fragment of IgG, high affinity Ia, receptor (CD64) Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr17_-_77386212	0.235	NM_001007533	DYSFIP1	dysferlin interacting protein 1
chr9_+_96561750	0.234	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr1_+_11917330	0.233	NM_000302	PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1
chr22_+_28206180	0.225	NM_021076	NEFH	neurofilament, heavy polypeptide
chr2_-_21120398	0.224		APOB	apolipoprotein B (including Ag(x) antigen)
chr7_+_143378393	0.221	NM_012365	OR2A5	olfactory receptor, family 2, subfamily A, member 5
chr7_+_113842284	0.215	NM_001172766 NM_014491 NM_148898 NM_148900	FOXP2	forkhead box P2
chr16_+_55523526	0.211		HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr20_-_604443	0.210
chr18_-_42798364	0.209	NM_001100817	TCEB3C TCEB3CL	transcription elongation factor B polypeptide 3C (elongin A3) transcription elongation factor B polypeptide 3C-like
chr7_-_75280962	0.207	NM_002991	CCL24	chemokine (C-C motif) ligand 24
chr19_+_39402167	0.204		LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)
chr6_-_88468667	0.204		AKIRIN2	akirin 2
chr5_+_176955595	0.202
chr16_+_22011362	0.199	NM_173615	VWA3A	von Willebrand factor A domain containing 3A
chr18_+_9698299	0.197		RAB31	RAB31, member RAS oncogene family
chr6_+_151603201	0.195		AKAP12	A kinase (PRKA) anchor protein 12
chr19_-_50975603	0.195	NM_001081563	DMPK	dystrophia myotonica-protein kinase
chr17_-_36181927	0.192	NM_181539	KRT26	keratin 26
chr20_-_61728774	0.189	NM_012384	GMEB2	glucocorticoid modulatory element binding protein 2
chr20_-_18425811	0.187	NM_006606	RBBP9	retinoblastoma binding protein 9
chr4_+_156899575	0.185	NM_000857	GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr4_-_88669267	0.185		SPARCL1	SPARC-like 1 (hevin)
chr2_+_138975819	0.184	NM_001001664	SPOPL	speckle-type POZ protein-like
chr10_+_6226884	0.182		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_-_121731721	0.180	NM_001024613 NM_001160264	FEZF1	FEZ family zinc finger 1
chr15_+_38462213	0.178	NM_001142761 NM_001142762 NM_033286	C15orf23	chromosome 15 open reading frame 23
chr22_+_24468168	0.176		MYO18B	myosin XVIIIB
chr20_-_62151216	0.173	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr7_+_113842470	0.171		FOXP2	forkhead box P2
chr16_-_67943157	0.171	NM_144676	TMED6	transmembrane emp24 protein transport domain containing 6
chr6_-_88468591	0.169		AKIRIN2	akirin 2
chr17_-_36938111	0.169	NM_002276	KRT19	keratin 19
chr1_-_120737416	0.168		FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr19_+_3536541	0.167	NM_133261	GIPC3	GIPC PDZ domain containing family, member 3
chr11_-_19180092	0.167	NM_001127656 NM_003476	CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr1_-_148080888	0.166	NM_001040874 NM_003516	HIST2H2AA4 HIST2H2AA3	histone cluster 2, H2aa4 histone cluster 2, H2aa3
chr15_+_38430517	0.165	NM_001145643	PHGR1	proline/histidine/glycine-rich 1
chr15_-_68177280	0.163		TLE3	transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chr2_+_138975946	0.160
chr1_-_166373434	0.159		GPR161	G protein-coupled receptor 161
chr1_-_925215	0.157		HES4	hairy and enhancer of split 4 (Drosophila)
chr2_-_151052391	0.157	NM_005168	RND3	Rho family GTPase 3
chr6_+_158322916	0.156		SYNJ2	synaptojanin 2
chr15_-_99847395	0.155		PCSK6	proprotein convertase subtilisin/kexin type 6
chr11_+_43920385	0.154	NM_001145033	C11orf96	chromosome 11 open reading frame 96
chr16_+_29984611	0.154		ALDOA	aldolase A, fructose-bisphosphate
chr10_+_6226764	0.154	NM_001145443	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chrX_-_152592450	0.154		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr15_+_79276273	0.150	NM_001172128	IL16	interleukin 16 (lymphocyte chemoattractant factor)
chr21_+_34112456	0.147		ITSN1	intersectin 1 (SH3 domain protein)
chr11_-_47330797	0.145	NM_000256	MYBPC3	myosin binding protein C, cardiac

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
6.79	6.18e-07	GO:0003012	muscle system process
6.96	1.41e-06	GO:0006936	muscle contraction
16.26	3.09e-06	GO:0070252	actin-mediated cell contraction
1.61	7.26e-06	GO:0032501	multicellular organismal process
12.12	4.89e-05	GO:0030048	actin filament-based movement
14.85	5.21e-05	GO:0030049	muscle filament sliding
14.85	5.21e-05	GO:0033275	actin-myosin filament sliding
5.60	8.83e-05	GO:0007517	muscle organ development
4.51	2.80e-04	GO:0061061	muscle structure development
1.66	2.51e-03	GO:0007275	multicellular organismal development
4.06	2.57e-03	GO:0030029	actin filament-based process
1.62	3.22e-03	GO:0032502	developmental process
2.82	3.48e-03	GO:0010628	positive regulation of gene expression
1.95	5.20e-03	GO:0048513	organ development
3.18	5.98e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
2.81	9.26e-03	GO:0045893	positive regulation of transcription, DNA-dependent
2.17	9.68e-03	GO:0010033	response to organic substance
1.65	1.33e-02	GO:0048856	anatomical structure development
2.53	1.48e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
2.62	2.83e-02	GO:0051254	positive regulation of RNA metabolic process
2.12	3.97e-02	GO:0031325	positive regulation of cellular metabolic process
1.67	4.28e-02	GO:0048518	positive regulation of biological process
1.65	4.45e-02	GO:0048731	system development
2.36	4.84e-02	GO:0031328	positive regulation of cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
10.33	1.15e-10	GO:0044449	contractile fiber part
9.49	4.77e-10	GO:0043292	contractile fiber
10.51	2.11e-09	GO:0030017	sarcomere
9.47	2.21e-09	GO:0030016	myofibril
4.56	7.71e-06	GO:0015629	actin cytoskeleton
11.45	7.65e-05	GO:0031674	I band
2.09	4.12e-04	GO:0005856	cytoskeleton
19.07	8.59e-04	GO:0005859	muscle myosin complex
17.17	1.52e-03	GO:0016460	myosin II complex
21.13	5.27e-03	GO:0031672	A band
7.51	7.27e-03	GO:0016459	myosin complex
11.45	1.24e-02	GO:0032432	actin filament bundle
10.41	1.99e-02	GO:0042641	actomyosin
2.28	2.02e-02	GO:0005615	extracellular space
10.10	2.31e-02	GO:0005884	actin filament
1.21	3.07e-02	GO:0043229	intracellular organelle
1.21	3.44e-02	GO:0043226	organelle
9.04	3.97e-02	GO:0030018	Z disc

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
12.78	3.60e-05	GO:0008307	structural constituent of muscle
1.40	5.57e-05	GO:0005515	protein binding
2.31	1.89e-03	GO:0030528	transcription regulator activity
2.67	2.77e-03	GO:0046983	protein dimerization activity
1.18	2.88e-03	GO:0005488	binding
3.48	3.55e-03	GO:0003779	actin binding
13.73	5.64e-03	GO:0017022	myosin binding
2.61	8.98e-03	GO:0005198	structural molecule activity
6.11	1.07e-02	GO:0003704	specific RNA polymerase II transcription factor activity
2.66	1.55e-02	GO:0008092	cytoskeletal protein binding
4.91	4.99e-02	GO:0008201	heparin binding