Motif ID: STAT1,3.p3

Z-value: 1.003


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT1chr2_-_191580567-0.572.8e-02Click!
STAT3chr17_-_377940170.534.2e-02Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_143706300 3.197 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_-_143706265 3.118 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706196 2.920 PDE4DIP
phosphodiesterase 4D interacting protein
chr5_+_149867866 2.526 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr1_-_151788341 1.616 NM_002960
S100A3
S100 calcium binding protein A3
chr3_-_52839727 1.448 NM_001166449
NM_002218
ITIH4

inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)

chr20_+_34019942 1.444 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr16_+_54072969 1.434 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr20_+_2743613 1.333 NM_080739
C20orf141
chromosome 20 open reading frame 141
chr11_-_64459910 1.288 NM_130769
GPHA2
glycoprotein hormone alpha 2
chr1_-_157313179 1.224 NM_004833
AIM2
absent in melanoma 2
chr14_+_99309688 1.211 EML1
echinoderm microtubule associated protein like 1
chr11_+_113672378 1.173 NNMT
nicotinamide N-methyltransferase
chr16_-_73012740 1.154 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr1_-_16411690 1.153 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr11_+_113672407 1.074 NNMT
nicotinamide N-methyltransferase
chr19_-_45022993 1.036 FBL
fibrillarin
chr1_-_6502655 1.015 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr16_+_68765428 1.011 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr9_+_135994734 0.988 NM_052821
WDR5
WD repeat domain 5
chrX_+_106030049 0.916 NM_001171092
CLDN2
claudin 2
chr2_-_70042900 0.896 NM_152792
ASPRV1
aspartic peptidase, retroviral-like 1
chr3_-_147696411 0.855 NM_020359
PLSCR2
phospholipid scramblase 2
chr11_-_62218759 0.760 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr11_+_46651090 0.759 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr16_+_88696172 0.729 FAM157C
family with sequence similarity 157, member C
chr22_+_19191875 0.728 MED15
mediator complex subunit 15
chr22_+_19191884 0.700 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr22_+_19191859 0.689 MED15
mediator complex subunit 15
chr19_-_4853878 0.689 NM_001080523
ARRDC5
arrestin domain containing 5
chr3_-_172109119 0.664 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr22_+_19191886 0.663 MED15
mediator complex subunit 15
chr11_-_121492010 0.657 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr19_-_60566419 0.642 NM_001145402
FAM71E2
family with sequence similarity 71, member E2
chr9_+_131937163 0.639 GPR107
G protein-coupled receptor 107
chr22_+_19191898 0.615 MED15
mediator complex subunit 15
chr16_-_3049336 0.596


chr9_-_129226312 0.593


chr4_-_185632610 0.577 NM_002199
IRF2
interferon regulatory factor 2
chr1_-_11841476 0.528 NM_002521
NPPB
natriuretic peptide B
chr1_-_159786150 0.521 FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr10_+_85994788 0.508 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr20_-_42713663 0.462 ADA
adenosine deaminase
chr9_+_129226535 0.440 ZNF79
zinc finger protein 79
chr2_+_165858586 0.433 NM_021007
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr3_-_172109075 0.429 EIF5A2
eukaryotic translation initiation factor 5A2
chr8_+_27238979 0.425 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr4_+_120029426 0.419 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr11_+_62380042 0.418 NM_001012662
NM_001012664
NM_002394
NM_001012661
NM_001012663
SLC3A2




solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2




chr19_-_61596681 0.404 NM_144690
ZNF582
zinc finger protein 582
chr6_-_27548438 0.391 NM_007149
ZNF184
zinc finger protein 184
chr9_+_129226473 0.391 NM_007135
ZNF79
zinc finger protein 79
chr19_-_56537189 0.390 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr20_-_5982617 0.388 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr1_-_52272020 0.375 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr1_-_201194083 0.372 NM_015999
ADIPOR1
adiponectin receptor 1
chr1_-_201422436 0.370 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_+_145807059 0.358 NM_001040006
NM_006706
TCERG1

transcription elongation regulator 1

chr2_+_170074457 0.355 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr11_-_4902144 0.346 NM_001005237
OR51G1
olfactory receptor, family 51, subfamily G, member 1
chr1_-_201422450 0.336 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_43606276 0.334 NM_022821
ELOVL1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr12_-_73889481 0.331 KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr1_-_201194062 0.330 ADIPOR1
adiponectin receptor 1
chr6_+_152168500 0.322 NM_001122741
ESR1
estrogen receptor 1
chr8_+_25372653 0.319 CDCA2
cell division cycle associated 2
chr15_-_41409979 0.316 NM_014793
LCMT2
leucine carboxyl methyltransferase 2
chr13_+_24844084 0.314 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr11_-_62379788 0.299 SNHG1
small nucleolar RNA host gene 1 (non-protein coding)
chr4_+_3413457 0.297 HGFAC
HGF activator
chr4_-_145281237 0.290 NM_002099
GYPA
glycophorin A (MNS blood group)
chr3_+_23962518 0.290 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr1_-_201422533 0.289 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr9_+_138997265 0.286 NM_207510
LCNL1
lipocalin-like 1
chr1_+_205328834 0.281 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr16_-_30705707 0.279 NM_001080417
ZNF629
zinc finger protein 629
chr19_-_63775901 0.273 MZF1
myeloid zinc finger 1
chr12_+_48792015 0.258 NM_032901
C12orf62
chromosome 12 open reading frame 62
chr9_-_106705867 0.258 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr18_-_50777634 0.257 NM_025214
CCDC68
coiled-coil domain containing 68
chr1_-_56750235 0.252 PPAP2B
phosphatidic acid phosphatase type 2B
chr19_-_13910167 0.250 NM_024825
PODNL1
podocan-like 1
chr8_+_25372631 0.250 CDCA2
cell division cycle associated 2
chr6_-_31007905 0.249 NM_205854
SFTA2
surfactant associated 2
chr1_+_58899 0.249 NM_001005484
OR4F4
OR4F5
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 5
chr6_+_36754433 0.248 NM_000389
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_-_201422368 0.244 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr5_-_39110235 0.240 RICTOR
RPTOR independent companion of MTOR, complex 2
chr1_-_201422490 0.236 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr11_+_61204392 0.236 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr7_-_149631001 0.234 NM_001164459
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr4_-_129429433 0.231 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr8_-_134184491 0.229 NM_001045556
NM_001045557
SLA

Src-like-adaptor

chr9_+_107496638 0.228 NM_018112
TMEM38B
transmembrane protein 38B
chr8_-_143856640 0.228 NM_023946
NM_177457
LYNX1

Ly6/neurotoxin 1

chr5_+_73145098 0.227 RGNEF
190 kDa guanine nucleotide exchange factor
chr17_-_73694669 0.224 NM_003258
TK1
thymidine kinase 1, soluble
chr1_-_159786441 0.220 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr4_+_3413489 0.220 NM_001528
HGFAC
HGF activator
chr5_-_39110251 0.216 NM_152756
RICTOR
RPTOR independent companion of MTOR, complex 2
chr5_-_16561936 0.215 NM_019000
FAM134B
family with sequence similarity 134, member B
chr22_+_19191964 0.207 MED15
mediator complex subunit 15
chr6_+_36754467 0.204 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr22_+_34374421 0.203 APOL6
apolipoprotein L, 6
chr19_-_844215 0.202 NM_005481
MED16
mediator complex subunit 16
chr12_-_6355165 0.202 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr19_-_844184 0.202 MED16
mediator complex subunit 16
chr5_-_133734616 0.199 CDKL3
cyclin-dependent kinase-like 3
chr14_+_73027361 0.198 NM_024644
C14orf169
chromosome 14 open reading frame 169
chr2_+_171494026 0.195 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr3_+_137224266 0.191 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr4_+_41235077 0.189 LIMCH1
LIM and calponin homology domains 1
chr17_-_39333490 0.189 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr12_+_108035424 0.183


chr12_-_49689255 0.181 SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr8_-_18710575 0.175 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr1_-_6376360 0.174 NM_007274
ACOT7
acyl-CoA thioesterase 7
chr3_+_134978615 0.174 TF
transferrin
chr6_-_25834733 0.171 NM_170745
HIST1H2AA
histone cluster 1, H2aa
chr2_-_19964873 0.169


chr1_+_205329206 0.168 NM_000716
NM_001017364
NM_001017367
C4BPB


complement component 4 binding protein, beta


chr5_+_133734768 0.164 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr9_-_87546620 0.164 NM_015239
AGTPBP1
ATP/GTP binding protein 1
chr19_+_45194782 0.163 NM_178544
ZNF546
zinc finger protein 546
chr17_+_5264195 0.161 RPAIN
RPA interacting protein
chr16_-_3707450 0.160 NM_016292
TRAP1
TNF receptor-associated protein 1
chr17_+_18796202 0.153 NM_001042450
NM_152351
SLC5A10

solute carrier family 5 (sodium/glucose cotransporter), member 10

chr22_+_34374358 0.153 NM_030641
APOL6
apolipoprotein L, 6
chr11_+_36572615 0.153 NM_138787
C11orf74
chromosome 11 open reading frame 74
chr10_+_91142301 0.153 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr19_+_49248003 0.151 NM_013361
ZNF223
zinc finger protein 223
chr8_-_143856179 0.150 LYNX1
Ly6/neurotoxin 1
chr2_+_30523586 0.149 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr15_-_73719546 0.147 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr17_-_45901173 0.145 NM_001267
CHAD
chondroadherin
chr10_-_38186984 0.144 ZNF248
zinc finger protein 248
chr12_+_11694172 0.144 ETV6
ets variant 6
chr7_-_87774130 0.142 NM_024636
STEAP4
STEAP family member 4
chr21_-_36774257 0.139 NM_001146079
NM_144492
CLDN14

claudin 14

chr11_-_128567302 0.138 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr3_-_42719322 0.138 NM_020707
HHATL
hedgehog acyltransferase-like
chr15_+_41410163 0.136 NM_001012969
NM_001159280
ADAL

adenosine deaminase-like

chr7_-_99411573 0.135 NM_001185
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr6_-_26038817 0.135 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr16_-_29817841 0.134 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr3_-_15875932 0.125 NM_015199
ANKRD28
ankyrin repeat domain 28
chr19_-_13909877 0.121 PODNL1
podocan-like 1
chr17_-_24491521 0.118 MYO18A
myosin XVIIIA
chr1_+_194887630 0.117 NM_000186
NM_001014975
CFH

complement factor H

chr14_-_91483757 0.114 NM_006329
FBLN5
fibulin 5
chr9_-_130078017 0.113 NM_004486
GOLGA2
golgin A2
chr20_+_24397834 0.112 NM_024893
TMEM90B
transmembrane protein 90B
chr2_-_85948287 0.111 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr10_+_64894943 0.111 LOC84989
hypothetical LOC84989
chr19_-_62759536 0.111 NM_001039654
ZNF550
zinc finger protein 550
chr11_+_73981274 0.110 NM_006591
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chrX_+_134693879 0.110 NM_001017436
NM_152582
CT45A3
CT45A4
CT45A2
cancer/testis antigen family 45, member A3
cancer/testis antigen family 45, member A4
cancer/testis antigen family 45, member A2
chr9_-_74757735 0.109 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr12_-_52975777 0.108 NM_006163
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr6_+_54819527 0.107 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr1_+_54291847 0.107 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr5_-_111340421 0.107 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr15_+_89300973 0.105 RCCD1
RCC1 domain containing 1
chr2_+_17798860 0.103 NM_001130009
LOC284952
GEN1
hypothetical protein LOC284952
Gen homolog 1, endonuclease (Drosophila)
chr22_-_18222337 0.101 C22orf29
chromosome 22 open reading frame 29
chr19_+_49408523 0.100 NM_182490
ZNF227
zinc finger protein 227
chr1_-_29381223 0.099 NM_005626
SRSF4
serine/arginine-rich splicing factor 4
chr16_-_55111461 0.098 NM_031885
BBS2
Bardet-Biedl syndrome 2
chr1_-_165112093 0.097 TADA1
transcriptional adaptor 1
chr17_+_71586857 0.096 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr1_+_45926433 0.095 NM_016486
TMEM69
transmembrane protein 69
chrX_-_106033202 0.093 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr19_+_49221333 0.092 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr1_-_54291634 0.091 NM_004872
TMEM59
transmembrane protein 59
chr6_+_32021831 0.091 CFB
complement factor B
chr17_+_68740952 0.088 C17orf80
chromosome 17 open reading frame 80
chr8_-_58068977 0.087 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr16_+_4546491 0.087 NM_001145011
LOC342346
hypothetical protein LOC342346
chr14_+_73027410 0.086 C14orf169
chromosome 14 open reading frame 169
chr6_-_32259974 0.086 NM_001136
NM_172197
AGER

advanced glycosylation end product-specific receptor

chr1_-_161380562 0.086 RGS5
regulator of G-protein signaling 5
chr12_+_2938703 0.083 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr15_+_24799174 0.083 NM_033223
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr16_+_4614959 0.082 MGRN1
mahogunin, ring finger 1
chr22_-_18222328 0.080 GNB1L
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
chr14_-_20128721 0.079 NM_001024822
RNASE12
ribonuclease, RNase A family, 12 (non-active)
chr1_-_20122638 0.078 NM_014589
PLA2G2E
phospholipase A2, group IIE
chrX_+_134803450 0.078 NM_018666
SAGE1
sarcoma antigen 1
chr17_+_29670171 0.077 NM_005623
CCL8
chemokine (C-C motif) ligand 8
chr15_+_89300995 0.077 RCCD1
RCC1 domain containing 1
chr5_+_178300799 0.077 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr7_-_100009205 0.075 NM_001168682
SAP25
sin3A-binding protein 25
chr22_-_49041786 0.074 MAPK12
mitogen-activated protein kinase 12
chr19_-_5790702 0.073 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr14_-_93988838 0.072 NM_001080451
SERPINA11
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr6_+_30238961 0.072 NM_033229
TRIM15
tripartite motif containing 15
chr7_-_44147436 0.071 NM_021223
MYL7
myosin, light chain 7, regulatory
chr3_+_37259684 0.071 NM_001172713
NM_002078
GOLGA4

golgin A4

chr12_+_120548831 0.069 NM_032790
ORAI1
ORAI calcium release-activated calcium modulator 1
chr1_-_25431544 0.069 NM_015484
NM_207170
SYF2

SYF2 homolog, RNA splicing factor (S. cerevisiae)


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.