Motif ID: TBP.p2

Z-value: 2.416


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TBPchr6_+_170705345-0.486.8e-02Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_36469869 4.003 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr21_-_44795769 3.438 NM_198693
KRTAP10-2
keratin associated protein 10-2
chr1_+_151596953 3.396 NM_002965
S100A9
S100 calcium binding protein A9
chr10_+_88770025 3.309 NM_001146157
FAM25A
family with sequence similarity 25, member A
chr12_-_51173238 3.216 NM_005554
KRT6A
keratin 6A
chr9_+_129951552 3.094 NM_005564
LCN2
lipocalin 2
chr1_-_151630168 2.992 NM_002964
S100A8
S100 calcium binding protein A8
chr1_+_150997129 2.894 NM_001025231
KPRP
keratinocyte proline-rich protein
chr17_-_37034288 2.879 NM_000422
KRT17
keratin 17
chr12_-_51153788 2.809 NM_173086
KRT6C
keratin 6C
chr10_+_47867667 2.665 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr1_+_151147646 2.494 NM_005547
IVL
involucrin
chr8_-_6722848 2.454 NM_005218
DEFB1
defensin, beta 1
chr11_+_1064869 2.444 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr3_+_150675169 2.414 TM4SF4
transmembrane 4 L six family member 4
chr11_-_102219450 2.377 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr17_-_36436979 2.363 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr16_-_11277806 2.333 NM_002762
PRM2
protamine 2
chr1_-_151784889 2.332 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr10_-_46601687 2.207 NM_001137556
NM_001137549
NM_001137548
FAM25B
FAM25G
FAM25C
family with sequence similarity 25, member B
family with sequence similarity 25, member G
family with sequence similarity 25, member C
chr17_-_37022465 2.190 NM_005557
KRT16
keratin 16
chr11_+_18244383 2.063 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr17_+_24598000 2.055 NM_005208
CRYBA1
crystallin, beta A1
chr1_+_151270301 1.967 NM_003125
SPRR1B
small proline-rich protein 1B
chr10_-_71871444 1.961 NM_018055
NODAL
nodal homolog (mouse)
chr9_-_33437527 1.945 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr2_-_219566364 1.941 NM_005209
NM_057093
NM_057094
CRYBA2


crystallin, beta A2


chr2_-_208702760 1.921 NM_020989
CRYGC
crystallin, gamma C
chr9_-_135074364 1.910 NM_014581
OBP2B
OBP2A
odorant binding protein 2B
odorant binding protein 2A
chr7_-_16811131 1.860 NM_006408
AGR2
anterior gradient homolog 2 (Xenopus laevis)
chr21_+_44844924 1.845 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr18_+_27425727 1.831 NM_000371
TTR
transthyretin
chr8_-_24869945 1.826 NM_006158
NEFL
neurofilament, light polypeptide
chr21_+_44818033 1.777 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr4_+_155703581 1.734 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr1_-_150564302 1.697 NM_002016
FLG
filaggrin
chr10_-_71871364 1.644 NODAL
nodal homolog (mouse)
chr1_-_117554999 1.637 NM_024626
VTCN1
V-set domain containing T cell activation inhibitor 1
chr2_-_75280121 1.633 NM_001058
NM_015727
TACR1

tachykinin receptor 1

chr8_-_143692814 1.621 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr5_-_42847716 1.621 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr17_-_45901173 1.602 NM_001267
CHAD
chondroadherin
chr11_-_18226743 1.602 NM_001127380
NM_030754
SAA2

serum amyloid A2

chr2_-_227952249 1.558 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr17_-_36475652 1.551 NM_033184
KRTAP2-4
keratin associated protein 2-4
chrX_+_152699616 1.549 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr16_-_55259405 1.533 NM_005950
MT1G
metallothionein 1G
chr17_-_76064842 1.495 NM_002522
NPTX1
neuronal pentraxin I
chr18_+_55038369 1.486 NM_001012512
NM_001012513
NM_002091
GRP


gastrin-releasing peptide


chr17_-_36719030 1.436 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr16_+_69950138 1.426 CALB2
calbindin 2
chr17_-_37144408 1.423 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr17_-_10265991 1.421 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr1_-_150805852 1.411 NM_178435
LCE3E
late cornified envelope 3E
chr5_-_179712920 1.386 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr16_+_69950116 1.375 NM_001740
NM_007088
CALB2

calbindin 2

chr14_+_30413393 1.366 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr1_+_45822246 1.362 NM_001195193
NM_002482
NM_152298
NASP


nuclear autoantigenic sperm protein (histone-binding)


chr2_-_238813284 1.359 HES6
hairy and enhancer of split 6 (Drosophila)
chr12_-_51132129 1.328 NM_005555
KRT6B
keratin 6B
chr9_-_103237851 1.312 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr5_-_153837975 1.308 HAND1
heart and neural crest derivatives expressed 1
chr10_+_118370441 1.302 NM_005396
PNLIPRP2
pancreatic lipase-related protein 2
chr6_-_3172775 1.297 NM_178012
TUBB2B
tubulin, beta 2B
chr1_-_148079357 1.297 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr16_+_70654625 1.288 NM_020995
HPR
haptoglobin-related protein
chr1_-_199732323 1.268 NM_001193572
CSRP1
cysteine and glycine-rich protein 1
chr7_+_127668566 1.264 NM_000230
LEP
leptin
chr1_-_2451543 1.262 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr2_-_238813365 1.248 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr1_-_154941861 1.239 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr16_+_155972 1.239 NM_001003938
HBM
hemoglobin, mu
chr20_-_38751289 1.234 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr21_+_44881700 1.233 NM_181688
KRTAP10-10
keratin associated protein 10-10
chr11_-_111287657 1.217 NM_001885
CRYAB
crystallin, alpha B
chr21_-_44911250 1.178 NM_181684
KRTAP12-2
keratin associated protein 12-2
chr1_-_150599105 1.157 NM_001014342
FLG2
filaggrin family member 2
chr11_-_102331643 1.155 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr1_-_151296611 1.152 NM_005988
SPRR2A
small proline-rich protein 2A
chr6_+_32021831 1.151 CFB
complement factor B
chr5_+_132237253 1.143 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr1_-_151280201 1.134 NM_006945
SPRR2D
small proline-rich protein 2D
chr6_-_3102690 1.111 NM_001069
TUBB2A
tubulin, beta 2A
chr2_-_240728745 1.099 NM_148961
OTOS
otospiralin
chr12_+_8866416 1.098 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr6_-_169395847 1.097 THBS2
thrombospondin 2
chr17_-_36792161 1.089 NM_021013
KRT34
keratin 34
chr1_+_148090804 1.088 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr19_+_40465249 1.077 NM_021175
HAMP
hepcidin antimicrobial peptide
chr12_-_49708279 1.073 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr11_+_70915960 1.062 NM_001012503
KRTAP5-7
keratin associated protein 5-7
chr19_+_38485583 1.051 LOC80054
hypothetical LOC80054
chr19_+_17979921 1.048 NM_015683
ARRDC2
arrestin domain containing 2
chr17_-_36807322 1.046 NM_002277
KRT31
keratin 31
chr17_-_36928604 1.044 NM_002275
KRT15
keratin 15
chr4_-_175680157 1.037 HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr16_+_55963899 1.037 NM_002996
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr11_-_93774223 1.035 NM_016540
GPR83
G protein-coupled receptor 83
chr11_-_6418705 1.008 NM_000613
HPX
hemopexin
chr9_-_116920232 1.008 NM_002160
TNC
tenascin C
chr6_-_30692995 1.001 NM_002714
PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr12_-_46405477 1.000 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr20_-_1922701 0.999 NM_001190899
NM_001190898
NM_024411
PDYN


prodynorphin


chr3_-_152529999 0.984 NM_176894
P2RY13
purinergic receptor P2Y, G-protein coupled, 13
chr11_-_116199145 0.977 NM_000482
APOA4
apolipoprotein A-IV
chr8_+_22075112 0.973 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr22_+_36412277 0.968 NM_024313
NOL12
nucleolar protein 12
chr1_+_17448179 0.961 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr11_-_102001259 0.933 NM_004771
MMP20
matrix metallopeptidase 20
chr17_-_36915329 0.932 NM_002274
NM_153490
KRT13

keratin 13

chr9_+_116125123 0.925 NM_000607
ORM1
orosomucoid 1
chrX_-_52843112 0.920 NM_001009616
SPANXN5
SPANX family, member N5
chr17_-_36456949 0.918 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr9_+_91409746 0.911 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr8_+_1980564 0.906 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr11_-_102100833 0.905 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chrX_+_153279764 0.905 NM_006013
RPL10
ribosomal protein L10
chr17_-_36451189 0.901 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr15_+_78858763 0.895 NM_018689
KIAA1199
KIAA1199
chr12_-_91063441 0.870 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr9_+_116131889 0.869 NM_000608
ORM2
orosomucoid 2
chr11_-_102250876 0.867 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr11_-_116213511 0.866 NM_000039
APOA1
apolipoprotein A-I
chr17_-_1478859 0.853 NM_152346
SLC43A2
solute carrier family 43, member 2
chr1_-_111771877 0.842 NM_002557
OVGP1
oviductal glycoprotein 1, 120kDa
chr12_+_53534565 0.839 NM_058173
MUCL1
mucin-like 1
chr17_+_36493927 0.818 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr21_-_44836811 0.798 NM_198688
KRTAP10-6
keratin associated protein 10-6
chr9_+_33785558 0.797 NM_002771
PRSS3
protease, serine, 3
chr12_+_100512877 0.791 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr15_+_43193810 0.761 NM_207581
DUOXA2
dual oxidase maturation factor 2
chr6_-_130224108 0.750 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr2_+_10779191 0.748 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr1_+_42391678 0.733 NM_007102
GUCA2B
guanylate cyclase activator 2B (uroguanylin)
chr1_-_228916486 0.732 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr4_-_46086218 0.718 GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr7_+_24290331 0.702 NM_000905
NPY
neuropeptide Y
chr16_-_2970474 0.690 NM_004203
NM_182687
PKMYT1

protein kinase, membrane associated tyrosine/threonine 1

chr19_-_60610792 0.689 UBE2S
ubiquitin-conjugating enzyme E2S
chr6_-_53517856 0.684 NM_001197115
NM_001498
GCLC

glutamate-cysteine ligase, catalytic subunit

chr1_-_224143389 0.681 NM_020997
LEFTY1
left-right determination factor 1
chr1_+_148089251 0.678 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr6_-_30188845 0.678 NM_007028
TRIM31
tripartite motif containing 31
chr1_-_228916470 0.671 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr19_-_18763077 0.665 NM_000095
COMP
cartilage oligomeric matrix protein
chr10_+_124310170 0.662 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr8_-_124622434 0.661 NM_058229
FBXO32
F-box protein 32
chr19_-_14490235 0.658 DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr8_+_23157094 0.657 NM_152272
CHMP7
CHMP family, member 7
chr11_+_66939720 0.652 NM_001166222
NM_020811
CARNS1

carnosine synthase 1

chr22_+_28206180 0.651 NM_021076
NEFH
neurofilament, heavy polypeptide
chr17_-_36165050 0.651 NM_181534
KRT25
keratin 25
chr14_-_80757018 0.649 NM_015859
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr6_-_30693003 0.646 PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr21_+_43024936 0.645 PDE9A
phosphodiesterase 9A
chr2_-_121759237 0.642 NM_014553
TFCP2L1
transcription factor CP2-like 1
chr6_+_19945578 0.641 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr6_-_2848460 0.633 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr8_+_24827181 0.627 NEFM
neurofilament, medium polypeptide
chr11_+_60886407 0.621 TMEM138
transmembrane protein 138
chr2_+_107969410 0.620 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chr3_+_42702014 0.619 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr17_-_36418869 0.618 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr14_+_92459244 0.615 CHGA
chromogranin A (parathyroid secretory protein 1)
chr1_-_150463292 0.611 NM_001009931
HRNR
hornerin
chr16_-_87378872 0.605 NM_001142864
FAM38A
family with sequence similarity 38, member A
chr9_-_138742420 0.596 SNORA43
SNHG7
small nucleolar RNA, H/ACA box 43
small nucleolar RNA host gene 7 (non-protein coding)
chrX_+_17303458 0.588 NM_198270
NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_+_111544469 0.586


chr2_-_142605739 0.585 NM_018557
LRP1B
low density lipoprotein receptor-related protein 1B
chr2_+_228386800 0.584 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr19_+_2427122 0.581 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr1_-_150398327 0.580 NM_001122965
RPTN
repetin
chr5_-_141981083 0.578 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr11_-_1026654 0.577 NM_005961
MUC6
mucin 6, oligomeric mucus/gel-forming
chr17_-_36760581 0.570 NM_004138
KRT33A
keratin 33A
chr16_+_84202515 0.569 NM_001134473
KIAA0182
KIAA0182
chr4_+_71330797 0.568 NM_001145006
MUC7
mucin 7, secreted
chr5_-_153838013 0.566 NM_004821
HAND1
heart and neural crest derivatives expressed 1
chr1_-_148080888 0.566 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr2_-_73373956 0.563 NM_001965
EGR4
early growth response 4
chr11_-_1576057 0.562 NM_001004325
KRTAP5-2
keratin associated protein 5-2
chr17_-_77386212 0.561 NM_001007533
DYSFIP1
dysferlin interacting protein 1
chr2_-_25245062 0.552 NM_000939
NM_001035256
POMC

proopiomelanocortin

chr12_-_50971516 0.548 NM_002281
KRT81
keratin 81
chr17_-_36113502 0.547 NM_019016
KRT24
keratin 24
chr11_-_62213577 0.546 LRRN4CL
LRRN4 C-terminal like
chr17_-_36877002 0.541 NM_002278
KRT32
keratin 32
chr12_+_10973100 0.539 NM_005042
NM_001110213
PRH2

proline-rich protein HaeIII subfamily 2

chr4_-_46086150 0.538 NM_001114175
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr1_+_159495140 0.534 NM_001102566
PCP4L1
Purkinje cell protein 4 like 1
chr5_+_53787187 0.532 NM_006308
HSPB3
heat shock 27kDa protein 3
chr1_-_150653351 0.529 NM_016190
CRNN
cornulin
chr6_-_27968906 0.525 NM_003514
HIST1H2AM
histone cluster 1, H2am
chr17_-_36192311 0.524 NM_181537
KRT27
keratin 27
chr8_+_24827173 0.523 NM_005382
NEFM
neurofilament, medium polypeptide
chr2_-_43307241 0.516 NM_006887
ZFP36L2
zinc finger protein 36, C3H type-like 2
chr20_+_3000265 0.516 NM_000915
OXT
oxytocin, prepropeptide
chr1_-_151310707 0.514 NM_001017418
SPRR2B
small proline-rich protein 2B
chr17_+_7494964 0.510 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.49 9.02e-10 GO:0032501 multicellular organismal process
1.99 9.61e-10 GO:0048513 organ development
2.55 5.22e-09 GO:0009888 tissue development
1.68 6.50e-09 GO:0048856 anatomical structure development
4.56 2.46e-08 GO:0008544 epidermis development
1.70 3.72e-08 GO:0048731 system development
6.00 1.35e-07 GO:0034728 nucleosome organization
6.31 1.60e-07 GO:0006334 nucleosome assembly
5.99 4.14e-07 GO:0031497 chromatin assembly
9.57 6.08e-07 GO:0031424 keratinization
1.57 7.61e-07 GO:0007275 multicellular organismal development
1.53 1.10e-06 GO:0032502 developmental process
5.07 1.21e-06 GO:0006323 DNA packaging
5.49 1.99e-06 GO:0065004 protein-DNA complex assembly
5.20 5.17e-06 GO:0071824 protein-DNA complex subunit organization
6.26 1.73e-05 GO:0009913 epidermal cell differentiation
4.36 2.04e-05 GO:0071103 DNA conformation change
3.34 3.29e-05 GO:0010035 response to inorganic substance
4.29 1.32e-04 GO:0006333 chromatin assembly or disassembly
6.28 1.64e-04 GO:0030216 keratinocyte differentiation
4.80 2.89e-04 GO:0008217 regulation of blood pressure
2.81 3.17e-04 GO:0034622 cellular macromolecular complex assembly
3.23 3.62e-04 GO:0009617 response to bacterium
2.47 5.79e-04 GO:0009607 response to biotic stimulus
1.61 7.27e-04 GO:0065008 regulation of biological quality
2.46 9.10e-04 GO:0034621 cellular macromolecular complex subunit organization
1.56 9.32e-04 GO:0006950 response to stress
2.02 1.03e-03 GO:0051704 multi-organism process
3.47 1.06e-03 GO:0003013 circulatory system process
3.47 1.06e-03 GO:0008015 blood circulation
3.53 1.49e-03 GO:0030855 epithelial cell differentiation
4.26 1.53e-03 GO:0042742 defense response to bacterium
2.03 1.94e-03 GO:0043933 macromolecular complex subunit organization
10.82 3.14e-03 GO:0045103 intermediate filament-based process
1.55 3.92e-03 GO:0042221 response to chemical stimulus
3.68 5.74e-03 GO:0042445 hormone metabolic process
9.83 6.54e-03 GO:0034367 macromolecular complex remodeling
9.83 6.54e-03 GO:0034368 protein-lipid complex remodeling
9.83 6.54e-03 GO:0034369 plasma lipoprotein particle remodeling
1.57 6.79e-03 GO:0030154 cell differentiation
2.44 9.35e-03 GO:0051707 response to other organism
3.25 9.95e-03 GO:0006979 response to oxidative stress
6.62 1.01e-02 GO:0034614 cellular response to reactive oxygen species
1.96 1.15e-02 GO:0006952 defense response
2.50 1.28e-02 GO:0060429 epithelium development
10.91 1.69e-02 GO:0045104 intermediate filament cytoskeleton organization
1.88 1.69e-02 GO:0050793 regulation of developmental process
3.12 1.73e-02 GO:0010817 regulation of hormone levels
1.53 2.13e-02 GO:0048869 cellular developmental process
2.11 2.21e-02 GO:0009887 organ morphogenesis
8.32 2.26e-02 GO:0071825 protein-lipid complex subunit organization
8.32 2.26e-02 GO:0071827 plasma lipoprotein particle organization
6.87 2.52e-02 GO:0044236 multicellular organismal metabolic process
8.01 2.97e-02 GO:0044243 multicellular organismal catabolic process
1.99 3.16e-02 GO:0065003 macromolecular complex assembly
5.15 3.25e-02 GO:0034599 cellular response to oxidative stress
7.73 3.85e-02 GO:0032963 collagen metabolic process
7.73 3.85e-02 GO:0070301 cellular response to hydrogen peroxide
4.17 4.51e-02 GO:0000302 response to reactive oxygen species

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
10.55 6.18e-41 GO:0005882 intermediate filament
9.13 5.79e-37 GO:0045111 intermediate filament cytoskeleton
13.91 1.92e-30 GO:0045095 keratin filament
2.31 4.67e-21 GO:0005576 extracellular region
2.95 1.58e-19 GO:0044421 extracellular region part
3.24 8.78e-19 GO:0005615 extracellular space
9.97 4.93e-13 GO:0000786 nucleosome
2.49 1.89e-12 GO:0044430 cytoskeletal part
2.15 7.47e-12 GO:0005856 cytoskeleton
1.72 1.29e-09 GO:0043228 non-membrane-bounded organelle
1.72 1.29e-09 GO:0043232 intracellular non-membrane-bounded organelle
6.37 5.15e-09 GO:0032993 protein-DNA complex
13.24 1.46e-06 GO:0001533 cornified envelope
12.02 1.65e-04 GO:0032982 myosin filament
1.41 2.84e-04 GO:0032991 macromolecular complex
3.05 3.71e-04 GO:0000785 chromatin
2.57 4.01e-04 GO:0031012 extracellular matrix
2.53 3.65e-03 GO:0005578 proteinaceous extracellular matrix
3.73 4.27e-03 GO:0030016 myofibril
5.35 7.55e-03 GO:0031983 vesicle lumen
3.52 8.31e-03 GO:0043292 contractile fiber
3.56 1.40e-02 GO:0044449 contractile fiber part
8.58 4.27e-02 GO:0005859 muscle myosin complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.57 1.14e-17 GO:0005198 structural molecule activity
7.18 1.72e-11 GO:0005179 hormone activity
2.29 9.26e-09 GO:0005102 receptor binding
6.47 2.39e-03 GO:0008307 structural constituent of muscle
4.79 4.96e-03 GO:0005200 structural constituent of cytoskeleton