Motif ID: TEAD1.p2

Z-value: 3.411


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_129173690.659.1e-03Click!
TEAD3chr6_-_35572694-0.563.1e-02Click!
TEAD4chr12_+_29387030.543.6e-02Click!
TEAD2chr19_-_545574500.029.3e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_90702490 13.130 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr6_-_132314004 8.375 NM_001901
CTGF
connective tissue growth factor
chr3_+_50281582 7.767 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_+_39664706 7.124 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr5_-_148422799 6.735 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr3_+_50281309 6.659 SEMA3B
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr22_+_40286957 6.075 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr11_+_1812115 5.377 NM_138567
SYT8
synaptotagmin VIII
chr19_-_13909877 5.042 PODNL1
podocan-like 1
chr6_-_42218692 4.807 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr4_-_152368492 4.774 SH3D19
SH3 domain containing 19
chr16_-_30983909 4.508 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr3_+_191588354 4.368 NM_006580
CLDN16
claudin 16
chr11_-_85108030 4.243 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr8_+_70541412 4.202 NM_001128204
NM_015170
SULF1

sulfatase 1

chr11_-_47427263 4.167 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr11_+_93394025 4.165 NM_001098672
HEPHL1
hephaestin-like 1
chr1_-_27604656 4.112 WASF2
WAS protein family, member 2
chr8_-_13018123 4.081 NM_001164271
DLC1
deleted in liver cancer 1
chr12_-_45506001 4.071 NM_001143824
NM_018018
SLC38A4

solute carrier family 38, member 4

chr12_-_15706340 4.009 EPS8
epidermal growth factor receptor pathway substrate 8
chr9_+_112470871 3.987 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr7_+_72883128 3.944 NM_001305
CLDN4
claudin 4
chr8_-_38505331 3.894 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr5_-_138822475 3.849 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr3_-_52844274 3.811 NM_205853
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr15_+_73728402 3.781 NM_153271
SNX33
sorting nexin 33
chr11_-_8789457 3.770 NM_139157
ST5
suppression of tumorigenicity 5
chr4_-_40326603 3.656 NM_001098634
RBM47
RNA binding motif protein 47
chr9_+_88953378 3.649 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr6_+_116956868 3.637 NM_153036
FAM26D
family with sequence similarity 26, member D
chr19_-_56204615 3.609 NM_012315
KLK9
kallikrein-related peptidase 9
chr7_+_134114701 3.561 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr5_+_152850276 3.490 NM_000827
NM_001114183
GRIA1

glutamate receptor, ionotropic, AMPA 1

chr1_-_199613406 3.453 TNNT2
troponin T type 2 (cardiac)
chr3_-_150533948 3.392 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr18_+_19947314 3.331 TTC39C
tetratricopeptide repeat domain 39C
chr1_-_54392030 3.273 NM_201546
CDCP2
CUB domain containing protein 2
chr14_-_22516271 3.247 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr18_+_30427279 3.219 NM_001128175
NM_001198938
NM_001198939
NM_001198940
DTNA



dystrobrevin, alpha



chr1_-_199613427 3.196 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr14_-_22515725 3.168 JUB
jub, ajuba homolog (Xenopus laevis)
chr6_+_152168500 3.111 NM_001122741
ESR1
estrogen receptor 1
chr11_-_85107569 3.105 NM_206929
SYTL2
synaptotagmin-like 2
chrX_-_13307425 3.081


chr15_+_61121806 3.075 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr2_+_95303947 3.045 PROM2
prominin 2
chr5_-_20024050 3.034 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr2_+_102169864 3.026 NM_003854
IL1RL2
interleukin 1 receptor-like 2
chr8_-_37847095 3.021 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr8_-_42184194 2.962 PLAT
plasminogen activator, tissue
chr11_-_2127368 2.960 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr10_-_116382089 2.898 ABLIM1
actin binding LIM protein 1
chr16_+_751050 2.895 NM_013404
MSLN
mesothelin
chr17_+_46267603 2.854 NM_175575
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr1_-_24311212 2.841 NM_152372
MYOM3
myomesin family, member 3
chr11_+_46651090 2.797 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr9_+_117955890 2.788 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr19_-_13910167 2.767 NM_024825
PODNL1
podocan-like 1
chr10_+_24538094 2.767 KIAA1217
KIAA1217
chrX_-_31436335 2.765 NM_004014
DMD
dystrophin
chr4_+_158361185 2.749 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr5_-_38631263 2.741 NM_002310
LIFR
leukemia inhibitory factor receptor alpha
chr7_-_100667750 2.701 NM_014343
CLDN15
claudin 15
chr1_-_201411533 2.623 NM_004997
MYBPH
myosin binding protein H
chr7_+_134114912 2.619 CALD1
caldesmon 1
chr2_+_95303922 2.600 NM_001165977
NM_001165978
NM_144707
PROM2


prominin 2


chr2_-_42844705 2.561 NM_148962
OXER1
oxoeicosanoid (OXE) receptor 1
chr14_-_22974707 2.532 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr17_-_31104009 2.523 NM_139285
GAS2L2
growth arrest-specific 2 like 2
chr5_+_140848905 2.515 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr8_-_42184350 2.475 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr2_-_189752575 2.465 NM_000393
COL5A2
collagen, type V, alpha 2
chr6_+_41712907 2.461 MDFI
MyoD family inhibitor
chr6_-_31188310 2.434 NM_014070
C6orf15
chromosome 6 open reading frame 15
chr15_+_46271158 2.404 NM_001145668
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr2_-_192420168 2.387 NM_004657
SDPR
serum deprivation response
chr17_+_7199178 2.382 NM_198154
TMEM95
transmembrane protein 95
chr19_-_4468715 2.373 NM_001080400
PLIN4
perilipin 4
chrX_-_114703273 2.363


chr5_-_83052606 2.308 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr11_+_57123927 2.299 SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_+_24522116 2.288 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr9_+_136673534 2.277 COL5A1
collagen, type V, alpha 1
chr5_-_58918031 2.270 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_-_238164452 2.248 NM_022449
RAB17
RAB17, member RAS oncogene family
chr2_-_160972606 2.244 RBMS1
RNA binding motif, single stranded interacting protein 1
chr18_+_50646616 2.239 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr5_+_34723420 2.227 NM_001145523
RAI14
retinoic acid induced 14
chr12_-_8706637 2.191 NM_003480
MFAP5
microfibrillar associated protein 5
chr12_-_94708641 2.183 NM_021229
NTN4
netrin 4
chr15_-_97366313 2.157 NM_001102612
PGPEP1L
pyroglutamyl-peptidase I-like
chr10_+_99334069 2.148 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr12_-_7136147 2.140 NM_001733
C1R
complement component 1, r subcomponent
chr15_-_39973566 2.137 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr19_-_56163815 2.131 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chrX_-_53327473 2.112 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr12_-_8706746 2.108 MFAP5
microfibrillar associated protein 5
chr5_+_121493113 2.093 NM_207317
ZNF474
zinc finger protein 474
chr7_+_94377145 2.079 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr19_-_13478037 2.074 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr6_+_42896771 2.068 NM_015349
KIAA0240
KIAA0240
chr1_+_114323552 2.063 NM_020190
OLFML3
olfactomedin-like 3
chr2_+_45732416 2.057 NM_005400
PRKCE
protein kinase C, epsilon
chr4_-_151990061 2.052 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr7_+_134114957 2.039 CALD1
caldesmon 1
chr12_-_120725210 2.034 LOC338799
hypothetical LOC338799
chr1_-_16217025 2.031 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr3_-_129023850 2.030 NM_007283
MGLL
monoglyceride lipase
chr2_+_113546365 1.998 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr2_+_102125616 1.987 IL1R1
interleukin 1 receptor, type I
chr5_-_140875591 1.967 DIAPH1
diaphanous homolog 1 (Drosophila)
chr8_-_108579270 1.962 NM_001146
ANGPT1
angiopoietin 1
chr12_-_7136189 1.935 C1R
complement component 1, r subcomponent
chr2_+_151922350 1.932 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr10_+_123862430 1.925 TACC2
transforming, acidic coiled-coil containing protein 2
chr1_+_17817397 1.920 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_159229606 1.903 NM_001195032
C6orf99
chromosome 6 open reading frame 99
chr10_+_99334411 1.897 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr3_-_135575925 1.894 NM_016201
AMOTL2
angiomotin like 2
chr9_+_130719034 1.887 LRRC8A
leucine rich repeat containing 8 family, member A
chr17_-_36347197 1.842 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr7_+_989321 1.829 NM_017781
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr2_-_73170290 1.818 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr3_+_125586241 1.806 KALRN
kalirin, RhoGEF kinase
chr4_+_41235077 1.800 LIMCH1
LIM and calponin homology domains 1
chr11_-_8788765 1.772 NM_213618
ST5
suppression of tumorigenicity 5
chr2_-_238164042 1.758 RAB17
RAB17, member RAS oncogene family
chrX_-_74292800 1.737 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr15_-_93671314 1.724 LOC400456
hypothetical LOC400456
chr2_-_233349469 1.710 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr18_+_3237527 1.709 NM_006471
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr21_-_26345294 1.708


chr9_+_122923864 1.698 CEP110
centrosomal protein 110kDa
chr10_+_24537725 1.694 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr3_-_12561962 1.687 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr18_-_51219880 1.677 TCF4
transcription factor 4
chr1_-_115039614 1.670 NM_000036
NM_001172626
AMPD1

adenosine monophosphate deaminase 1

chr5_+_118719591 1.663 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr9_+_111927601 1.661 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr22_+_22907417 1.637 SUSD2
sushi domain containing 2
chr22_-_43986896 1.634 KIAA0930
KIAA0930
chr12_-_119172339 1.625 NM_025157
PXN
paxillin
chr16_-_62573 1.608 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr17_+_45404677 1.587 DLX4
distal-less homeobox 4
chr14_+_94117483 1.587 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr9_+_129951552 1.586 NM_005564
LCN2
lipocalin 2
chr1_-_151788341 1.582 NM_002960
S100A3
S100 calcium binding protein A3
chr1_-_3437834 1.580 MEGF6
multiple EGF-like-domains 6
chr22_+_22907443 1.578 NM_019601
SUSD2
sushi domain containing 2
chr12_-_8706533 1.568 MFAP5
microfibrillar associated protein 5
chr10_-_99436889 1.563 NM_021732
AVPI1
arginine vasopressin-induced 1
chr19_-_56147971 1.561 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr12_+_51728999 1.560 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr6_+_31190505 1.548 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr1_+_176577228 1.548 NM_004841
RASAL2
RAS protein activator like 2
chr11_-_65082705 1.541 LTBP3
latent transforming growth factor beta binding protein 3
chr16_-_21344158 1.525 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr6_+_134251940 1.516 NM_198392
NM_003206
TCF21

transcription factor 21

chr20_+_30409649 1.504 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr14_+_20537253 1.496 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr10_-_123346148 1.491 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr18_-_44723116 1.484 NM_001190823
SMAD7
SMAD family member 7
chr1_+_238321794 1.484 NM_020066
FMN2
formin 2
chr3_+_25444753 1.478 NM_016152
RARB
retinoic acid receptor, beta
chr3_-_150569574 1.474 TM4SF1
transmembrane 4 L six family member 1
chr18_-_19496590 1.468 NM_173505
ANKRD29
ankyrin repeat domain 29
chr21_-_30614477 1.462 NM_203405
KRTAP26-1
keratin associated protein 26-1
chr6_+_134251957 1.458 TCF21
transcription factor 21
chr6_+_53991672 1.450 NM_138569
C6orf142
chromosome 6 open reading frame 142
chr7_-_155297576 1.437 NM_000193
SHH
sonic hedgehog
chr16_-_73012740 1.422 NM_001011880
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr9_+_130723507 1.417 PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr5_-_39461054 1.406 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr20_-_5982617 1.381 NM_152611
LRRN4
leucine rich repeat neuronal 4
chr12_-_61830882 1.369 AVPR1A
arginine vasopressin receptor 1A
chr3_+_148609841 1.368 NM_003412
ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr9_-_72673753 1.356 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr1_-_212791597 1.355 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr3_-_113842553 1.354 CCDC80
coiled-coil domain containing 80
chr11_-_124311106 1.348 HEPACAM
hepatic and glial cell adhesion molecule
chr12_+_26239755 1.348 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr6_+_30958672 1.347 DDR1
discoidin domain receptor tyrosine kinase 1
chr15_+_40353657 1.346 NM_198141
GANC
glucosidase, alpha; neutral C
chr20_-_3635774 1.326 NM_023068
SIGLEC1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr17_-_3445873 1.324 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr7_+_989472 1.322 CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr4_+_8322358 1.322 NM_053044
HTRA3
HtrA serine peptidase 3
chr11_+_113671744 1.319 NM_006169
NNMT
nicotinamide N-methyltransferase
chr11_-_126375895 1.315 NM_001161707
NM_032531
KIRREL3

kin of IRRE like 3 (Drosophila)

chr15_+_61122139 1.313 TPM1
tropomyosin 1 (alpha)
chr11_+_116580892 1.311 TAGLN
transgelin
chr5_-_58607673 1.301 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_26973804 1.292 ARID1A
AT rich interactive domain 1A (SWI-like)
chr7_+_143263191 1.284 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr11_+_58146721 1.282 NM_000614
CNTF
ciliary neurotrophic factor
chr5_-_37871685 1.271 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr1_-_151848039 1.249 S100A16
S100 calcium binding protein A16
chr1_+_150997129 1.244 NM_001025231
KPRP
keratinocyte proline-rich protein
chr11_+_19328846 1.232 NM_001111018
NAV2
neuron navigator 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.52 1.43e-05 GO:0005576 extracellular region
2.26 1.34e-04 GO:0031012 extracellular matrix
3.44 2.12e-04 GO:0044420 extracellular matrix part
2.31 4.86e-04 GO:0005578 proteinaceous extracellular matrix
15.42 9.25e-04 GO:0005587 collagen type IV
1.63 1.58e-03 GO:0044421 extracellular region part
13.22 3.09e-03 GO:0030935 sheet-forming collagen
5.14 5.03e-03 GO:0005581 collagen
3.70 6.61e-03 GO:0005604 basement membrane
12.34 4.12e-02 GO:0001527 microfibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.70 2.48e-03 GO:0005201 extracellular matrix structural constituent
1.90 2.91e-03 GO:0008092 cytoskeletal protein binding
1.80 3.11e-03 GO:0005509 calcium ion binding
2.11 1.01e-02 GO:0003779 actin binding
1.16 1.23e-02 GO:0005515 protein binding
7.40 4.16e-02 GO:0043236 laminin binding