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• Mean activities

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• Activity deltas table
• Regulatory interactions
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Motif ID: TFAP2{A,C}.p2

Z-value: 3.041

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_-_39964001	2.818		CHADL	chondroadherin-like
chr11_-_60819110	2.565		VWCE	von Willebrand factor C and EGF domains
chr2_+_176695658	2.435	NM_014213	HOXD9	homeobox D9
chr15_+_39573363	2.348	NM_002220	ITPKA	inositol 1,4,5-trisphosphate 3-kinase A
chr5_+_176170041	2.194	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr19_+_39664706	1.996	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr22_-_45311730	1.826	NM_014246	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr11_-_60819273	1.790	NM_152718	VWCE	von Willebrand factor C and EGF domains
chr2_+_120820140	1.722	NM_002193	INHBB	inhibin, beta B
chr2_-_47650973	1.708	NM_022055	KCNK12	potassium channel, subfamily K, member 12
chr2_-_45090025	1.686	NM_016932	SIX2	SIX homeobox 2
chr2_-_236741352	1.617	NM_001485	GBX2	gastrulation brain homeobox 2
chr5_+_129268352	1.518	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr10_-_28074752	1.515	NM_173576	MKX	mohawk homeobox
chr4_-_85638410	1.514	NM_006168	NKX6-1	NK6 homeobox 1
chr3_+_71885890	1.488	NM_018971	GPR27	G protein-coupled receptor 27
chr8_+_104582151	1.388	NM_001100117	RIMS2	regulating synaptic membrane exocytosis 2
chr16_+_66244314	1.386		RLTPR	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr17_+_29931880	1.349	NM_207313	TMEM132E	transmembrane protein 132E
chr17_+_45993338	1.346	NM_018896 NM_198376 NM_198377 NM_198378 NM_198379 NM_198380 NM_198382 NM_198383 NM_198384 NM_198385 NM_198386 NM_198387 NM_198388 NM_198396 NM_198397	CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit
chr9_+_94987032	1.340	NM_006648	WNK2	WNK lysine deficient protein kinase 2
chr11_+_62136788	1.334	NM_000327	ROM1	retinal outer segment membrane protein 1
chr5_+_170668892	1.327	NM_021025	TLX3	T-cell leukemia homeobox 3
chr5_-_94646033	1.327	NM_024717	MCTP1	multiple C2 domains, transmembrane 1
chr6_+_19945578	1.304	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr19_+_50004134	1.298	NM_001013257 NM_005581	BCAM	basal cell adhesion molecule (Lutheran blood group)
chr10_+_122206455	1.290	NM_001030059	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A
chr2_+_176702667	1.256	NM_019558	HOXD8	homeobox D8
chr6_+_41714171	1.253	NM_005586	MDFI	MyoD family inhibitor
chr15_+_49421004	1.249	NM_181789	GLDN	gliomedin
chr1_+_33494745	1.227	NM_152493	ZNF362	zinc finger protein 362
chr3_-_130807865	1.187	NM_015103	PLXND1	plexin D1
chr7_-_150495799	1.175	NM_001098834	GBX1	gastrulation brain homeobox 1
chr2_+_176680251	1.167	NM_021192	HOXD11	homeobox D11
chr7_-_123460722	1.162	NM_001136002	TMEM229A	transmembrane protein 229A
chr12_-_1573591	1.161	NM_152441	FBXL14	F-box and leucine-rich repeat protein 14
chr2_+_241586927	1.160	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr21_+_36993860	1.151	NM_005069 NM_009586	SIM2	single-minded homolog 2 (Drosophila)
chr4_-_123092358	1.150	NM_001130698	TRPC3	transient receptor potential cation channel, subfamily C, member 3
chr17_-_59131194	1.142		LIMD2	LIM domain containing 2
chr10_+_101079099	1.137		CNNM1	cyclin M1
chr7_+_140420500	1.132	NM_001195278	LOC100131199	transmembrane protein 178-like
chr20_-_55274497	1.125		BMP7	bone morphogenetic protein 7
chr19_+_38804694	1.122	NM_001127895 NM_001127896	CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
chr10_-_76829857	1.110		ZNF503	zinc finger protein 503
chr16_-_49742651	1.105	NM_002968	SALL1	sal-like 1 (Drosophila)
chr15_-_66511488	1.103	NM_001004439	ITGA11	integrin, alpha 11
chr10_+_42892506	1.094	NM_020630 NM_020975	RET	ret proto-oncogene
chr12_+_2032649	1.093	NM_000719 NM_001129827 NM_001129829 NM_001129830 NM_001129831 NM_001129832 NM_001129833 NM_001129834 NM_001129835 NM_001129836 NM_001129837 NM_001129838 NM_001129839 NM_001129840 NM_001129841 NM_001129842 NM_001129843 NM_001129844 NM_001129846 NM_001167623 NM_001167624 NM_001167625 NM_199460	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit
chr13_+_87122778	1.082	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr7_+_94374862	1.066	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr10_+_80672842	1.061		ZMIZ1	zinc finger, MIZ-type containing 1
chr10_-_131652364	1.055		EBF3	early B-cell factor 3
chr10_-_99780336	1.052		CRTAC1	cartilage acidic protein 1
chr11_-_407324	1.052	NM_001135053 NM_021805	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr22_+_29361672	1.046	NM_001001479	SLC35E4	solute carrier family 35, member E4
chr17_+_56831951	1.043	NM_005994	TBX2	T-box 2
chr6_+_5030718	1.042	NM_001145115	PPP1R3G	protein phosphatase 1, regulatory (inhibitor) subunit 3G
chr12_+_109956210	1.040	NM_015267	CUX2	cut-like homeobox 2
chr7_-_35260213	1.038	NM_001077653 NM_001166220	TBX20	T-box 20
chr1_-_6243621	1.037	NM_207370	GPR153	G protein-coupled receptor 153
chr10_+_120779217	1.030	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr5_-_172594691	1.027	NM_001166175 NM_001166176 NM_004387	NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)
chr18_+_18969724	1.026	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr6_+_1336077	1.011
chr3_+_148610516	1.005		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr20_+_60810610	0.998	NM_002531	NTSR1	neurotensin receptor 1 (high affinity)
chr2_-_219633481	0.998	NM_002181	IHH	Indian hedgehog
chr17_+_56832255	0.995		TBX2	T-box 2
chr11_+_7229976	0.991		SYT9	synaptotagmin IX
chr13_+_30378311	0.991	NM_032849	C13orf33	chromosome 13 open reading frame 33
chr3_-_124650081	0.990	NM_183357	ADCY5	adenylate cyclase 5
chr19_-_51081147	0.981	NM_015649	IRF2BP1	interferon regulatory factor 2 binding protein 1
chr2_-_135193011	0.977	NM_030923	TMEM163	transmembrane protein 163
chr22_-_22440054	0.968	NM_213720	CHCHD10	coiled-coil-helix-coiled-coil-helix domain containing 10
chr1_+_2975590	0.967	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr22_-_17891777	0.964		CLDN5	claudin 5
chr18_+_53253775	0.960	NM_004852	ONECUT2	one cut homeobox 2
chr1_-_99242765	0.952	NM_001010861 NM_001037317	LPPR5	lipid phosphate phosphatase-related protein type 5
chr10_-_123347493	0.947	NM_000141 NM_001144917 NM_001144918 NM_001144919 NM_022970	FGFR2	fibroblast growth factor receptor 2
chr20_-_43953036	0.942	NM_080749	NEURL2	neuralized homolog 2 (Drosophila)
chr6_-_117193505	0.941	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr10_-_88116181	0.938	NM_017551	GRID1	glutamate receptor, ionotropic, delta 1
chr3_+_50687675	0.936	NM_004947	DOCK3	dedicator of cytokinesis 3
chr2_-_39040981	0.936		LOC375196	hypothetical LOC375196
chr20_-_4177519	0.935	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr10_+_123912930	0.934		TACC2	transforming, acidic coiled-coil containing protein 2
chr1_+_153560351	0.932	NM_001105205	RUSC1	RUN and SH3 domain containing 1
chr1_-_6468108	0.931		PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr11_-_65082208	0.929	NM_001130144 NM_001164266 NM_021070	LTBP3	latent transforming growth factor beta binding protein 3
chr12_+_93066370	0.928	NM_005761	PLXNC1	plexin C1
chr9_+_134027154	0.923	NM_032536	NTNG2	netrin G2
chr14_+_68796621	0.919		GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr12_-_56418295	0.918	NM_001122772	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chrX_+_68641802	0.911	NM_015686	FAM155B	family with sequence similarity 155, member B
chr1_-_1157284	0.903	NM_016176 NM_016547	SDF4	stromal cell derived factor 4
chr3_+_182912769	0.903		SOX2	SRY (sex determining region Y)-box 2
chr16_+_19087035	0.898	NM_016524	SYT17	synaptotagmin XVII
chr12_-_120389419	0.896		KDM2B	lysine (K)-specific demethylase 2B
chr1_+_112852892	0.894	NM_024494	WNT2B	wingless-type MMTV integration site family, member 2B
chr11_-_45643711	0.891	NM_003654	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr4_+_19864332	0.887	NM_004787	SLIT2	slit homolog 2 (Drosophila)
chr8_-_144583718	0.884	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr1_+_229365296	0.880	NM_001004342	TRIM67	tripartite motif containing 67
chr6_+_1335067	0.880	NM_001452	FOXF2	forkhead box F2
chr3_-_71886203	0.876	NM_001134649	EIF4E3	eukaryotic translation initiation factor 4E family member 3
chr13_-_94162249	0.875	NM_007084	SOX21	SRY (sex determining region Y)-box 21
chr11_+_63829616	0.873	NM_004451	ESRRA	estrogen-related receptor alpha
chr3_+_50217692	0.870	NM_006841	SLC38A3	solute carrier family 38, member 3
chr14_+_89597860	0.865	NM_022054	KCNK13	potassium channel, subfamily K, member 13
chr11_+_74629597	0.856	NM_001195528	LOC441617	hypothetical LOC441617
chr20_-_21326046	0.855	NM_033176	NKX2-4	NK2 homeobox 4
chr12_+_6363482	0.853	NM_002342	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)
chr20_+_254205	0.852	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr15_+_82113813	0.851	NM_207517	ADAMTSL3	ADAMTS-like 3
chr14_+_69021149	0.848	NM_001161498	UPF0639	UPF0639 protein
chr3_+_129690735	0.846
chr11_-_65082705	0.843		LTBP3	latent transforming growth factor beta binding protein 3
chr17_+_1906262	0.841	NM_001098202	HIC1	hypermethylated in cancer 1
chr1_-_94779727	0.838	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr14_-_100104014	0.828	NM_001159531	BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)
chr1_-_38285033	0.827	NM_002699	POU3F1	POU class 3 homeobox 1
chr14_-_64416307	0.825		SPTB	spectrin, beta, erythrocytic
chr1_+_226937732	0.824		RHOU	ras homolog gene family, member U
chr2_+_46623396	0.824		RHOQ	ras homolog gene family, member Q
chr17_+_52026058	0.823	NM_005450	NOG	noggin
chr16_+_52877009	0.823
chr1_-_25128951	0.822		RUNX3	runt-related transcription factor 3
chr4_+_185064799	0.821		STOX2	storkhead box 2
chr14_-_59001603	0.820		GPR135	G protein-coupled receptor 135
chr3_-_24511456	0.817		THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr21_-_27139143	0.816		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr10_-_134449467	0.815	NM_177400	NKX6-2	NK6 homeobox 2
chr1_+_22909916	0.815	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr9_-_139316523	0.808	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr17_+_62391216	0.806	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr13_+_95541093	0.804	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr9_+_136673534	0.802		COL5A1	collagen, type V, alpha 1
chr1_+_100777044	0.800		GPR88	G protein-coupled receptor 88
chr20_-_24986501	0.799		ACSS1	acyl-CoA synthetase short-chain family member 1
chr11_+_7229717	0.797	NM_175733	SYT9	synaptotagmin IX
chr19_-_51168396	0.796	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr16_+_65591916	0.794	NM_001190201 NM_001190202	CES4A	carboxylesterase 4A
chr8_-_97242119	0.794	NM_001001557	GDF6	growth differentiation factor 6
chr18_-_22383066	0.792	NM_001136205	KCTD1	potassium channel tetramerisation domain containing 1
chrX_-_53367246	0.789	NM_001111125	IQSEC2	IQ motif and Sec7 domain 2
chr17_+_72376022	0.789	NM_144677	MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B
chr22_-_49315341	0.788	NM_001113755 NM_001953	TYMP	thymidine phosphorylase
chr22_-_30071565	0.783		PATZ1	POZ (BTB) and AT hook containing zinc finger 1
chr10_+_50488352	0.780	NM_003055	SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3
chr7_-_27206249	0.775	NM_000522	HOXA13	homeobox A13
chr2_-_236740710	0.774
chr15_-_38362078	0.773	NM_001190479	LOC100131244	hypothetical protein LOC100131244
chr19_+_45389356	0.772	NM_002446	MAP3K10	mitogen-activated protein kinase kinase kinase 10
chr18_-_53621277	0.768	NM_005603	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr16_-_76026431	0.763	NM_199355	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr11_+_93917214	0.761		FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr8_-_53640520	0.760	NM_207413	FAM150A	family with sequence similarity 150, member A
chr20_+_30019465	0.760	NM_001011718	XKR7	XK, Kell blood group complex subunit-related family, member 7
chr17_-_6400470	0.759	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr10_-_118491971	0.758	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr20_+_56659693	0.757	NM_001001433 NM_001134772 NM_001134773 NM_003763	STX16	syntaxin 16
chr15_+_97462675	0.755	NM_015286 NM_145728	SYNM	synemin, intermediate filament protein
chr9_+_128128913	0.753	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr13_+_77170470	0.751	NM_001040153	SLAIN1	SLAIN motif family, member 1
chr1_-_202387767	0.751	NM_018208	ETNK2	ethanolamine kinase 2
chr21_+_36993302	0.750
chr3_+_50167851	0.749	NM_004186	SEMA3F	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_26924466	0.748	NM_020134	DPYSL5	dihydropyrimidinase-like 5
chr14_-_76677711	0.746		ZDHHC22	zinc finger, DHHC-type containing 22
chr22_+_48740432	0.744		PIM3	pim-3 oncogene
chr5_+_140326473	0.744	NM_031883	PCDHAC2	protocadherin alpha subfamily C, 2
chr20_+_41976831	0.743	NM_001098797	TOX2	TOX high mobility group box family member 2
chr17_+_40655060	0.738	NM_005892	FMNL1	formin-like 1
chr3_+_161425946	0.737	NM_001168214	LOC401097	hypothetical protein LOC401097
chr7_-_103417198	0.737	NM_005045 NM_173054	RELN	reelin
chr16_-_626293	0.736	NM_001040160 NM_001040161 NM_001040162 NM_001040165 NM_032366	C16orf13	chromosome 16 open reading frame 13
chr22_+_30072739	0.734		FLJ20464	hypothetical protein FLJ20464
chr9_+_128416542	0.734	NM_001174146 NM_001174147 NM_002316	LMX1B	LIM homeobox transcription factor 1, beta
chr18_-_22382497	0.734	NM_001142730	KCTD1	potassium channel tetramerisation domain containing 1
chr14_-_102045849	0.733	NM_152326	ANKRD9	ankyrin repeat domain 9
chr10_+_123913094	0.732	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr2_+_26768894	0.732	NM_002246	KCNK3	potassium channel, subfamily K, member 3
chr1_-_11674264	0.732	NM_001127325	MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)
chr7_+_154943466	0.728	NM_001427	EN2	engrailed homeobox 2
chr2_+_171280944	0.726		SP5	Sp5 transcription factor
chr14_-_94306104	0.721	NM_173849	GSC	goosecoid homeobox
chr9_-_119217147	0.718		ASTN2	astrotactin 2
chr7_-_100325209	0.717	NM_001015072	UFSP1	UFM1-specific peptidase 1 (non-functional)
chr10_-_88271466	0.716		WAPAL	wings apart-like homolog (Drosophila)
chr1_-_152741148	0.713	NM_001010846	SHE	Src homology 2 domain containing E
chr22_-_32646325	0.711	NM_004737 NM_133642	LARGE	like-glycosyltransferase
chr17_-_45582872	0.711	NM_032595	PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B
chr4_-_5945596	0.710	NM_001014809	CRMP1	collapsin response mediator protein 1
chr1_-_50661716	0.709	NM_032110	DMRTA2	DMRT-like family A2
chr7_-_131911808	0.708	NM_001105543 NM_020911	PLXNA4	plexin A4
chr15_+_64782468	0.706		SMAD6	SMAD family member 6
chr6_+_137285071	0.705	NM_001008783	SLC35D3	solute carrier family 35, member D3
chr16_-_11257539	0.705	NM_003745	SOCS1	suppressor of cytokine signaling 1
chr9_-_138150200	0.704		C9orf69	chromosome 9 open reading frame 69

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.07	5.22e-23	GO:0009987	cellular process
1.10	6.23e-17	GO:0065007	biological regulation
1.10	5.85e-16	GO:0050789	regulation of biological process
1.10	3.71e-15	GO:0050794	regulation of cellular process
1.14	4.03e-14	GO:0044260	cellular macromolecule metabolic process
1.11	2.04e-13	GO:0044237	cellular metabolic process
1.09	6.03e-12	GO:0008152	metabolic process
1.12	2.83e-11	GO:0043170	macromolecule metabolic process
1.10	1.20e-10	GO:0044238	primary metabolic process
1.17	7.25e-10	GO:0048522	positive regulation of cellular process
1.16	2.21e-09	GO:0071842	cellular component organization at cellular level
1.16	2.57e-09	GO:0071841	cellular component organization or biogenesis at cellular level
1.15	1.75e-08	GO:0048518	positive regulation of biological process
1.28	3.05e-08	GO:0048699	generation of neurons
1.13	4.95e-08	GO:0016043	cellular component organization
1.12	5.19e-08	GO:0019222	regulation of metabolic process
1.27	5.43e-08	GO:0022008	neurogenesis
1.13	8.14e-08	GO:0071840	cellular component organization or biogenesis
1.20	8.69e-08	GO:0007399	nervous system development
1.12	1.28e-07	GO:0031323	regulation of cellular metabolic process
1.20	1.36e-07	GO:0009653	anatomical structure morphogenesis
1.29	3.46e-07	GO:0030182	neuron differentiation
1.18	9.86e-07	GO:0023051	regulation of signaling
1.16	1.00e-06	GO:0048523	negative regulation of cellular process
1.25	1.13e-06	GO:0048468	cell development
1.12	1.28e-06	GO:0080090	regulation of primary metabolic process
1.15	2.80e-06	GO:0048519	negative regulation of biological process
1.29	3.17e-06	GO:0032989	cellular component morphogenesis
1.12	3.56e-06	GO:0060255	regulation of macromolecule metabolic process
1.13	9.77e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	1.22e-05	GO:0009966	regulation of signal transduction
1.11	3.58e-05	GO:0006807	nitrogen compound metabolic process
1.31	3.88e-05	GO:0000904	cell morphogenesis involved in differentiation
1.26	4.25e-05	GO:0009790	embryo development
1.22	4.69e-05	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.10	5.39e-05	GO:0032502	developmental process
1.15	5.98e-05	GO:0006464	protein modification process
1.28	6.22e-05	GO:0048666	neuron development
1.16	6.35e-05	GO:0006996	organelle organization
1.11	6.91e-05	GO:0051179	localization
1.27	7.59e-05	GO:0000902	cell morphogenesis
1.14	8.76e-05	GO:0090304	nucleic acid metabolic process
1.30	8.88e-05	GO:0031175	neuron projection development
1.15	9.10e-05	GO:0043412	macromolecule modification
1.26	1.08e-04	GO:0030030	cell projection organization
1.11	1.13e-04	GO:0034641	cellular nitrogen compound metabolic process
1.12	1.21e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12	1.73e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.14	2.29e-04	GO:0048869	cellular developmental process
1.15	2.44e-04	GO:0048583	regulation of response to stimulus
1.30	2.66e-04	GO:0048646	anatomical structure formation involved in morphogenesis
1.14	2.96e-04	GO:0030154	cell differentiation
1.10	3.00e-04	GO:0007275	multicellular organismal development
1.12	3.04e-04	GO:0044267	cellular protein metabolic process
1.11	3.07e-04	GO:0048731	system development
1.21	4.51e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.10	4.76e-04	GO:0023052	signaling
1.12	5.13e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.20	6.66e-04	GO:0009892	negative regulation of metabolic process
1.19	7.14e-04	GO:0043067	regulation of programmed cell death
1.21	8.58e-04	GO:0016265	death
1.36	9.38e-04	GO:0001944	vasculature development
1.28	9.91e-04	GO:0072358	cardiovascular system development
1.28	9.91e-04	GO:0072359	circulatory system development
1.29	1.04e-03	GO:0048667	cell morphogenesis involved in neuron differentiation
1.30	1.05e-03	GO:0007409	axonogenesis
1.19	1.06e-03	GO:0010941	regulation of cell death
1.37	1.09e-03	GO:0001568	blood vessel development
1.17	1.11e-03	GO:0009893	positive regulation of metabolic process
1.18	1.22e-03	GO:0031325	positive regulation of cellular metabolic process
1.12	1.24e-03	GO:0010556	regulation of macromolecule biosynthetic process
1.24	1.30e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.29	1.34e-03	GO:0048812	neuron projection morphogenesis
1.10	1.50e-03	GO:0048856	anatomical structure development
1.18	1.51e-03	GO:0010646	regulation of cell communication
1.27	1.51e-03	GO:0032990	cell part morphogenesis
1.27	1.53e-03	GO:0048858	cell projection morphogenesis
1.20	1.54e-03	GO:0031324	negative regulation of cellular metabolic process
1.33	1.63e-03	GO:0007411	axon guidance
1.20	1.90e-03	GO:0008219	cell death
1.17	1.92e-03	GO:0010604	positive regulation of macromolecule metabolic process
1.18	2.20e-03	GO:0042981	regulation of apoptosis
1.11	2.27e-03	GO:0009889	regulation of biosynthetic process
1.18	2.33e-03	GO:0007049	cell cycle
1.23	2.47e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.24	2.91e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.10	3.03e-03	GO:0019538	protein metabolic process
1.23	3.26e-03	GO:0010628	positive regulation of gene expression
1.11	3.31e-03	GO:0031326	regulation of cellular biosynthetic process
1.26	3.86e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.38	4.01e-03	GO:0002009	morphogenesis of an epithelium
1.11	4.04e-03	GO:0010468	regulation of gene expression
1.22	4.40e-03	GO:0009890	negative regulation of biosynthetic process
1.09	4.58e-03	GO:0007165	signal transduction
1.38	5.47e-03	GO:0048011	nerve growth factor receptor signaling pathway
1.15	5.73e-03	GO:0035556	intracellular signal transduction
1.08	6.87e-03	GO:0051716	cellular response to stimulus
1.12	6.98e-03	GO:0006355	regulation of transcription, DNA-dependent
1.10	7.15e-03	GO:0051234	establishment of localization
1.15	7.44e-03	GO:0065009	regulation of molecular function
1.11	8.49e-03	GO:0051252	regulation of RNA metabolic process
1.24	8.96e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.41	9.23e-03	GO:0035239	tube morphogenesis
1.20	1.11e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
1.32	1.18e-02	GO:0048729	tissue morphogenesis
1.22	1.27e-02	GO:0045893	positive regulation of transcription, DNA-dependent
1.21	1.32e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.47	1.40e-02	GO:0030111	regulation of Wnt receptor signaling pathway
1.44	1.52e-02	GO:0060562	epithelial tube morphogenesis
1.18	1.59e-02	GO:0006351	transcription, DNA-dependent
1.20	1.59e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	1.78e-02	GO:0010629	negative regulation of gene expression
1.23	2.03e-02	GO:0051253	negative regulation of RNA metabolic process
1.09	2.13e-02	GO:0006810	transport
1.44	2.21e-02	GO:0045165	cell fate commitment
1.21	2.34e-02	GO:0045595	regulation of cell differentiation
1.20	2.40e-02	GO:0012501	programmed cell death
1.15	2.43e-02	GO:0051641	cellular localization
1.18	3.28e-02	GO:0050793	regulation of developmental process
1.19	3.51e-02	GO:0031399	regulation of protein modification process
1.21	3.61e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.16	4.09e-02	GO:0032268	regulation of cellular protein metabolic process
1.22	4.44e-02	GO:0000278	mitotic cell cycle
1.21	4.63e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.12	4.96e-02	GO:0034645	cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	2.96e-26	GO:0044424	intracellular part
1.07	3.21e-25	GO:0005622	intracellular
1.09	3.94e-20	GO:0043227	membrane-bounded organelle
1.09	7.17e-20	GO:0005737	cytoplasm
1.09	1.36e-19	GO:0043231	intracellular membrane-bounded organelle
1.08	2.75e-19	GO:0043226	organelle
1.08	6.94e-19	GO:0043229	intracellular organelle
1.11	4.13e-13	GO:0044446	intracellular organelle part
1.11	5.04e-13	GO:0044422	organelle part
1.10	9.56e-12	GO:0044444	cytoplasmic part
1.10	1.49e-11	GO:0005634	nucleus
1.17	1.28e-09	GO:0044428	nuclear part
1.20	5.07e-09	GO:0012505	endomembrane system
1.15	3.55e-07	GO:0031090	organelle membrane
1.14	7.73e-07	GO:0070013	intracellular organelle lumen
1.16	1.35e-06	GO:0031981	nuclear lumen
1.14	2.06e-06	GO:0043233	organelle lumen
1.14	2.16e-06	GO:0031974	membrane-enclosed lumen
1.14	2.15e-05	GO:0005829	cytosol
1.30	1.17e-04	GO:0043005	neuron projection
1.19	1.70e-04	GO:0005794	Golgi apparatus
1.02	2.36e-04	GO:0005623	cell
1.02	2.71e-04	GO:0044464	cell part
1.24	3.54e-04	GO:0044431	Golgi apparatus part
1.45	1.16e-03	GO:0005912	adherens junction
1.15	1.79e-03	GO:0005654	nucleoplasm
1.25	2.38e-03	GO:0000139	Golgi membrane
1.09	2.85e-03	GO:0043234	protein complex
1.31	3.11e-03	GO:0015629	actin cytoskeleton
1.49	6.40e-03	GO:0030055	cell-substrate junction
1.42	1.30e-02	GO:0031301	integral to organelle membrane
1.48	1.34e-02	GO:0005924	cell-substrate adherens junction
1.48	1.75e-02	GO:0005925	focal adhesion
1.14	1.93e-02	GO:0005783	endoplasmic reticulum
1.36	2.86e-02	GO:0070161	anchoring junction
1.09	3.62e-02	GO:0043228	non-membrane-bounded organelle
1.09	3.62e-02	GO:0043232	intracellular non-membrane-bounded organelle
1.16	3.72e-02	GO:0042995	cell projection

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.13	8.45e-29	GO:0005515	protein binding
1.06	6.12e-18	GO:0005488	binding
1.26	4.56e-10	GO:0030528	transcription regulator activity
1.29	9.75e-08	GO:0043565	sequence-specific DNA binding
1.23	3.24e-07	GO:0001071	nucleic acid binding transcription factor activity
1.23	3.24e-07	GO:0003700	sequence-specific DNA binding transcription factor activity
1.30	1.01e-04	GO:0019904	protein domain specific binding
1.33	3.55e-04	GO:0016563	transcription activator activity
1.22	7.69e-03	GO:0008092	cytoskeletal protein binding
1.10	7.76e-03	GO:0003677	DNA binding
1.19	1.11e-02	GO:0019899	enzyme binding
1.19	1.27e-02	GO:0042802	identical protein binding
1.28	1.79e-02	GO:0016564	transcription repressor activity
1.10	2.74e-02	GO:0000166	nucleotide binding
1.06	3.73e-02	GO:0003824	catalytic activity
1.26	4.68e-02	GO:0003779	actin binding