• All motifs sorted by activity significance
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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP2B.p2

Z-value: 2.392

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_48951286	2.384	NM_001160300 NM_052839	PANX2	pannexin 2
chr20_-_61933012	2.231		ZBTB46	zinc finger and BTB domain containing 46
chr16_+_87047159	1.983		ZFPM1	zinc finger protein, multitype 1
chr3_-_130807865	1.735	NM_015103	PLXND1	plexin D1
chr20_+_20296744	1.679	NM_002196	INSM1	insulinoma-associated 1
chr8_-_144583718	1.592	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr15_-_62854749	1.548	NM_194272	RBPMS2	RNA binding protein with multiple splicing 2
chr17_-_34015631	1.524	NM_025248	SRCIN1	SRC kinase signaling inhibitor 1
chr9_+_123501186	1.487		DAB2IP	DAB2 interacting protein
chr16_+_88169612	1.481	NM_014427 NM_153636	CPNE7	copine VII
chr14_+_104338423	1.478		ZBTB42	zinc finger and BTB domain containing 42
chr20_-_60963390	1.414	NM_006602	TCFL5	transcription factor-like 5 (basic helix-loop-helix)
chr10_+_120779217	1.405	NM_199461	NANOS1	nanos homolog 1 (Drosophila)
chr1_+_39729885	1.398	NM_181809	BMP8A	bone morphogenetic protein 8a
chr9_+_137511448	1.398	NM_014811	KIAA0649	KIAA0649
chr4_+_2031036	1.385	NM_178557	NAT8L	N-acetyltransferase 8-like (GCN5-related, putative)
chr19_+_39664706	1.374	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr10_-_99175685	1.364
chr1_-_38285033	1.360	NM_002699	POU3F1	POU class 3 homeobox 1
chr7_-_150495799	1.350	NM_001098834	GBX1	gastrulation brain homeobox 1
chr22_+_38075703	1.307	NM_004711 NM_145731	SYNGR1	synaptogyrin 1
chr21_-_43671355	1.304	NM_173354	SIK1	salt-inducible kinase 1
chr16_-_87535106	1.271	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr12_+_119562737	1.255	NM_001033677	CABP1	calcium binding protein 1
chr1_+_22909916	1.251	NM_004442 NM_017449	EPHB2	EPH receptor B2
chr11_+_1367665	1.249	NM_003957	BRSK2	BR serine/threonine kinase 2
chr11_+_279113	1.220	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr5_+_176170041	1.203	NM_133369	UNC5A	unc-5 homolog A (C. elegans)
chr11_+_93917214	1.174		FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
chr4_-_1692574	1.123		TMEM129	transmembrane protein 129
chr4_+_1842833	1.120	NM_001042424	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr22_-_48607449	1.119		BRD1	bromodomain containing 1
chr22_-_37569962	1.106	NM_014293	NPTXR	neuronal pentraxin receptor
chr22_+_21742727	1.105		GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr4_+_1842947	1.084		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr4_-_809879	1.068	NM_006651	CPLX1	complexin 1
chr13_-_98536640	1.052	NM_001130049 NM_015296	DOCK9	dedicator of cytokinesis 9
chr2_+_241586927	1.051	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr4_-_1692776	1.051	NM_001127266 NM_138385	TMEM129	transmembrane protein 129
chr22_+_18081968	1.050	NM_002688	SEPT5	septin 5
chr2_+_101680594	1.048	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_13436802	1.031	NM_024923	NUP210	nucleoporin 210kDa
chr17_+_75849221	1.027	NM_020914 NM_020954	RNF213	ring finger protein 213
chr12_+_95112385	1.016		ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr1_+_52871603	1.010	NM_001042693	FAM159A	family with sequence similarity 159, member A
chr4_+_3264509	1.010		RGS12	regulator of G-protein signaling 12
chr1_-_229242567	1.000		FAM89A	family with sequence similarity 89, member A
chr17_+_8865547	0.982	NM_004822	NTN1	netrin 1
chr20_-_44370537	0.982		CDH22	cadherin 22, type 2
chr16_+_87047418	0.981	NM_153813	ZFPM1	zinc finger protein, multitype 1
chr1_+_41022066	0.980	NM_004700 NM_172163	KCNQ4	potassium voltage-gated channel, KQT-like subfamily, member 4
chr22_+_20101661	0.975	NM_015094	HIC2	hypermethylated in cancer 2
chr1_-_111019051	0.973
chr13_-_109236897	0.973	NM_003749	IRS2	insulin receptor substrate 2
chr7_-_5427367	0.963
chr19_-_14177980	0.958	NM_001008701 NM_014921	LPHN1	latrophilin 1
chr17_+_27838041	0.958	NM_003885	CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr16_-_3870714	0.958		CREBBP	CREB binding protein
chr5_+_1061900	0.956	NM_033120	NKD2	naked cuticle homolog 2 (Drosophila)
chr8_-_41873401	0.950	NM_001142446	ANK1	ankyrin 1, erythrocytic
chr22_+_21742364	0.947	NM_002073	GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide
chr7_-_100331417	0.941	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr4_-_957269	0.936		DGKQ	diacylglycerol kinase, theta 110kDa
chr14_-_104333123	0.932	NM_001014431 NM_001014432	AKT1	v-akt murine thymoma viral oncogene homolog 1
chr22_+_21852911	0.932		BCR	breakpoint cluster region
chr1_-_229242594	0.931	NM_198552	FAM89A	family with sequence similarity 89, member A
chr16_-_87378872	0.931	NM_001142864	FAM38A	family with sequence similarity 38, member A
chr16_-_8964751	0.926	NM_003470	USP7	ubiquitin specific peptidase 7 (herpes virus-associated)
chr11_-_64268841	0.923	NM_001098670	RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr14_+_102313566	0.917	NM_003300 NM_145725 NM_145726	TRAF3	TNF receptor-associated factor 3
chr4_-_41848874	0.916		BEND4	BEN domain containing 4
chr16_+_11669736	0.914	NM_003498	SNN	stannin
chr17_+_75366524	0.912	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr2_-_235070431	0.911	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr10_+_134060681	0.909	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr19_+_18391211	0.903	NM_001009998 NM_032627	SSBP4	single stranded DNA binding protein 4
chr2_+_170298487	0.893
chr1_+_39319675	0.890	NM_012090	MACF1	microtubule-actin crosslinking factor 1
chr20_+_2621193	0.886	NM_001110514	EBF4	early B-cell factor 4
chr4_+_2764609	0.886		SH3BP2	SH3-domain binding protein 2
chr16_+_49139694	0.878	NM_033119	NKD1	naked cuticle homolog 1 (Drosophila)
chr16_-_1404635	0.866	NM_001037125 NM_001193388	UNKL	unkempt homolog (Drosophila)-like
chr9_+_95378492	0.859	NM_005392	PHF2	PHD finger protein 2
chr16_+_2461500	0.857	NM_006181	NTN3	netrin 3
chr8_-_145122884	0.853	NM_000445	PLEC	plectin
chr7_+_882704	0.851	NM_015949	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr19_+_18391423	0.851
chr6_+_1556543	0.841		FOXC1	forkhead box C1
chr4_-_41849333	0.838		BEND4	BEN domain containing 4
chr22_-_40652724	0.836	NM_052945	TNFRSF13C	tumor necrosis factor receptor superfamily, member 13C
chr22_+_27931685	0.833	NM_133455	EMID1	EMI domain containing 1
chr22_-_37180958	0.827	NM_152868	KCNJ4	potassium inwardly-rectifying channel, subfamily J, member 4
chr10_+_72826656	0.825	NM_001171930 NM_001171931 NM_001171932 NM_022124 NM_052836	CDH23	cadherin-related 23
chr22_-_37569679	0.824
chr19_-_44503328	0.823
chr14_-_104333060	0.822		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr21_+_45888001	0.816		PCBP3	poly(rC) binding protein 3
chr19_-_1518875	0.805	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr7_-_150576660	0.805	NM_001003801	SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr16_-_3870686	0.804		CREBBP	CREB binding protein
chr5_-_72779585	0.802		FOXD1	forkhead box D1
chr1_-_6243621	0.793	NM_207370	GPR153	G protein-coupled receptor 153
chr22_-_49042065	0.792	NM_002969	MAPK12	mitogen-activated protein kinase 12
chr17_+_24944605	0.788	NM_152345	ANKRD13B	ankyrin repeat domain 13B
chr12_+_622374	0.788		LOC100049716	hypothetical LOC100049716
chr20_-_60375695	0.782	NM_005560	LAMA5	laminin, alpha 5
chr7_-_150576634	0.781		SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr6_-_119441045	0.780		FAM184A	family with sequence similarity 184, member A
chr19_-_17217022	0.777	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr7_+_3307445	0.774	NM_152744	SDK1	sidekick homolog 1, cell adhesion molecule (chicken)
chr13_-_112392051	0.762		LOC440149	hypothetical LOC440149
chr11_-_110087982	0.761		ARHGAP20	Rho GTPase activating protein 20
chr16_+_716936	0.757	NM_207112 NM_032304	HAGHL	hydroxyacylglutathione hydrolase-like
chr19_-_1188840	0.754	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr9_-_100510657	0.753	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chr22_+_18499354	0.751	NM_001185024 NM_013373	ZDHHC8	zinc finger, DHHC-type containing 8
chr6_+_167970334	0.750	NM_001040000	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr2_+_42128521	0.746	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr22_-_17517795	0.744	NM_005315	GSC2	goosecoid homeobox 2
chr17_+_1574782	0.737	NM_001163809	WDR81	WD repeat domain 81
chr16_-_4106186	0.737	NM_001116	ADCY9	adenylate cyclase 9
chr19_+_1397268	0.736		APC2	adenomatosis polyposis coli 2
chr17_-_77512346	0.735	NM_178493	NOTUM	notum pectinacetylesterase homolog (Drosophila)
chr9_-_139183675	0.735
chr5_-_1348103	0.733	NM_001193376 NM_198253	TERT	telomerase reverse transcriptase
chr3_-_53054999	0.732		SFMBT1	Scm-like with four mbt domains 1
chr20_+_61841553	0.731	NM_020062	SLC2A4RG	SLC2A4 regulator
chr5_+_10617431	0.730	NM_001164440	ANKRD33B	ankyrin repeat domain 33B
chr11_-_2863536	0.730	NM_000076 NM_001122630 NM_001122631	CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr13_+_95541093	0.720	NM_153456	HS6ST3	heparan sulfate 6-O-sulfotransferase 3
chr22_-_27405708	0.717	NM_001145418	TTC28	tetratricopeptide repeat domain 28
chr17_+_40192072	0.717	NM_002390	ADAM11	ADAM metallopeptidase domain 11
chr19_+_52215982	0.714	NM_002517	NPAS1	neuronal PAS domain protein 1
chr4_+_1764802	0.711	NM_000142 NM_001163213 NM_022965	FGFR3	fibroblast growth factor receptor 3
chr15_+_97009194	0.708		IGF1R	insulin-like growth factor 1 receptor
chr9_-_139068269	0.705	NM_001246 NM_203468	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr19_+_540849	0.702	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr1_-_29321599	0.702	NM_001171868	TMEM200B	transmembrane protein 200B
chr1_-_111018798	0.697		KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3
chr17_+_27617307	0.697	NM_138328	RHBDL3	rhomboid, veinlet-like 3 (Drosophila)
chr16_-_2186465	0.695	NM_020764	CASKIN1	CASK interacting protein 1
chr11_+_66643311	0.692	NM_012308	KDM2A	lysine (K)-specific demethylase 2A
chr9_+_138497767	0.691	NM_152571	C9orf163	chromosome 9 open reading frame 163
chr22_-_45311730	0.690	NM_014246	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr3_-_186353321	0.688		C3orf70	chromosome 3 open reading frame 70
chr14_-_102045849	0.688	NM_152326	ANKRD9	ankyrin repeat domain 9
chr22_+_36286350	0.684	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr20_-_61108831	0.684	NM_080606	BHLHE23	basic helix-loop-helix family, member e23
chr6_-_3401733	0.680	NM_015482	SLC22A23	solute carrier family 22, member 23
chr14_+_102313585	0.680		TRAF3	TNF receptor-associated factor 3
chr22_+_18085990	0.680		SEPT5-GP1BB SEPT5	SEPT5-GP1BB read-through transcript septin 5
chr9_-_93225780	0.679		NFIL3	nuclear factor, interleukin 3 regulated
chr17_+_78630793	0.678	NM_001004431	METRNL	meteorin, glial cell differentiation regulator-like
chr22_+_21852551	0.675	NM_004327 NM_021574	BCR	breakpoint cluster region
chr9_+_138680064	0.673		EGFL7	EGF-like-domain, multiple 7
chr11_-_1549719	0.665	NM_004420	DUSP8	dual specificity phosphatase 8
chr15_+_62230962	0.665	NM_024798	SNX22	sorting nexin 22
chr4_-_140317686	0.663		ELF2	E74-like factor 2 (ets domain transcription factor)
chr7_+_50314801	0.662	NM_006060	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr3_+_61522922	0.660		PTPRG	protein tyrosine phosphatase, receptor type, G
chr19_+_16296632	0.659	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr7_-_156495985	0.659	NM_005515	MNX1	motor neuron and pancreas homeobox 1
chr7_+_882766	0.655		GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr2_-_6923215	0.653	NM_207315	CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr9_+_102275310	0.653	NM_003692	TMEFF1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr17_-_40401138	0.651	NM_006688	C1QL1	complement component 1, q subcomponent-like 1
chr19_+_2240996	0.649
chr22_+_48633484	0.647	NM_014838	ZBED4	zinc finger, BED-type containing 4
chr17_-_58877276	0.646	NM_001017916 NM_001915	CYB561	cytochrome b-561
chr8_-_8788149	0.645	NM_004225	MFHAS1	malignant fibrous histiocytoma amplified sequence 1
chr22_-_49041786	0.644		MAPK12	mitogen-activated protein kinase 12
chr9_-_99994704	0.643	NM_052820	CORO2A	coronin, actin binding protein, 2A
chr3_-_186353421	0.643	NM_001025266	C3orf70	chromosome 3 open reading frame 70
chr1_-_1274160	0.642	NM_004421	DVL1	dishevelled, dsh homolog 1 (Drosophila)
chr15_-_63457378	0.640	NM_004884	IGDCC3	immunoglobulin superfamily, DCC subclass, member 3
chr17_+_72880967	0.638		SEPT9	septin 9
chr16_+_550394	0.636	NM_145270	C16orf11	chromosome 16 open reading frame 11
chr5_-_1577022	0.635	NM_024830	LPCAT1	lysophosphatidylcholine acyltransferase 1
chr1_+_25817197	0.635		MAN1C1	mannosidase, alpha, class 1C, member 1
chr22_+_18124225	0.634	NM_005992 NM_080646 NM_080647	TBX1	T-box 1
chr1_-_32574185	0.634	NM_023009	MARCKSL1	MARCKS-like 1
chr20_-_38751289	0.631	NM_005461	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr20_-_62151216	0.627	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr1_+_2149993	0.626	NM_003036	SKI	v-ski sarcoma viral oncogene homolog (avian)
chr17_-_4841628	0.626	NM_001167985 NM_001167986 NM_001167987 NM_213726	INCA1	inhibitor of CDK, cyclin A1 interacting protein 1
chr1_-_111019148	0.625	NM_002232	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3
chr1_+_63561632	0.621		FOXD3	forkhead box D3
chr16_+_24985721	0.619		LOC283887	hypothetical protein LOC283887
chr7_+_45580704	0.617		ADCY1	adenylate cyclase 1 (brain)
chr2_-_232103352	0.617	NM_006056	NMUR1	neuromedin U receptor 1
chr20_+_56899643	0.617	NM_001077489 NM_000516 NM_080426	GNAS	GNAS complex locus
chr17_+_78070853	0.616	NM_004514	FOXK2	forkhead box K2
chr11_+_45900731	0.615		GYLTL1B	glycosyltransferase-like 1B
chr6_+_157722467	0.615	NM_024630 NM_153746	ZDHHC14	zinc finger, DHHC-type containing 14
chr22_+_18085891	0.614		SEPT5	septin 5
chr7_-_139987044	0.611		DENND2A	DENN/MADD domain containing 2A
chr3_+_161425946	0.611	NM_001168214	LOC401097	hypothetical protein LOC401097
chr4_-_957327	0.611	NM_001347	DGKQ	diacylglycerol kinase, theta 110kDa
chr9_-_97318760	0.610		PTCH1	patched 1
chr15_-_72513053	0.609	NM_001146030	SEMA7A	semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.10	4.16e-32	GO:0009987	cellular process
1.16	2.45e-22	GO:0044237	cellular metabolic process
1.15	6.58e-22	GO:0050794	regulation of cellular process
1.13	2.72e-18	GO:0050789	regulation of biological process
1.12	3.60e-18	GO:0065007	biological regulation
1.20	3.37e-16	GO:0031323	regulation of cellular metabolic process
1.27	2.33e-15	GO:0048523	negative regulation of cellular process
1.12	3.23e-15	GO:0008152	metabolic process
1.25	3.86e-15	GO:0048519	negative regulation of biological process
1.17	1.39e-14	GO:0044260	cellular macromolecule metabolic process
1.20	2.28e-14	GO:0080090	regulation of primary metabolic process
1.32	2.43e-14	GO:0009653	anatomical structure morphogenesis
1.18	4.90e-14	GO:0019222	regulation of metabolic process
1.18	2.20e-13	GO:0032502	developmental process
1.30	2.23e-13	GO:0023051	regulation of signaling
1.31	4.95e-13	GO:0007399	nervous system development
1.13	5.60e-13	GO:0044238	primary metabolic process
1.23	2.05e-12	GO:0048522	positive regulation of cellular process
1.19	5.46e-12	GO:0060255	regulation of macromolecule metabolic process
1.21	7.48e-12	GO:0048518	positive regulation of biological process
1.18	2.01e-11	GO:0007275	multicellular organismal development
1.38	7.39e-11	GO:0048699	generation of neurons
1.37	1.35e-10	GO:0022008	neurogenesis
1.20	1.45e-10	GO:0031326	regulation of cellular biosynthetic process
1.18	2.07e-10	GO:0048856	anatomical structure development
1.29	3.22e-10	GO:0009966	regulation of signal transduction
1.20	4.08e-10	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	4.45e-10	GO:0051171	regulation of nitrogen compound metabolic process
1.21	5.59e-10	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.19	1.15e-09	GO:0009889	regulation of biosynthetic process
1.28	1.30e-09	GO:0035556	intracellular signal transduction
1.23	1.61e-09	GO:0043412	macromolecule modification
1.20	4.69e-09	GO:0010468	regulation of gene expression
1.23	5.25e-09	GO:0006464	protein modification process
1.39	7.85e-09	GO:0009790	embryo development
1.16	8.20e-09	GO:0016043	cellular component organization
1.41	1.12e-08	GO:0032989	cellular component morphogenesis
1.45	1.26e-08	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.19	1.30e-08	GO:0071842	cellular component organization at cellular level
1.21	1.55e-08	GO:0048869	cellular developmental process
1.42	1.64e-08	GO:0000902	cell morphogenesis
1.18	1.64e-08	GO:0048731	system development
1.13	1.75e-08	GO:0043170	macromolecule metabolic process
1.40	2.03e-08	GO:0007167	enzyme linked receptor protein signaling pathway
1.41	2.45e-08	GO:0010629	negative regulation of gene expression
1.19	2.96e-08	GO:0010556	regulation of macromolecule biosynthetic process
1.33	3.67e-08	GO:0010605	negative regulation of macromolecule metabolic process
1.18	5.10e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.20	5.18e-08	GO:0051252	regulation of RNA metabolic process
1.45	5.19e-08	GO:0000904	cell morphogenesis involved in differentiation
1.31	7.94e-08	GO:0009892	negative regulation of metabolic process
1.15	9.72e-08	GO:0071840	cellular component organization or biogenesis
1.31	1.07e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.21	1.42e-07	GO:0030154	cell differentiation
1.32	1.59e-07	GO:0048468	cell development
1.19	1.79e-07	GO:0044249	cellular biosynthetic process
1.27	2.43e-07	GO:0031325	positive regulation of cellular metabolic process
1.36	2.93e-07	GO:0030182	neuron differentiation
1.45	4.80e-07	GO:0048667	cell morphogenesis involved in neuron differentiation
1.19	6.10e-07	GO:0006355	regulation of transcription, DNA-dependent
1.41	8.17e-07	GO:0032990	cell part morphogenesis
1.26	9.97e-07	GO:0009893	positive regulation of metabolic process
1.41	1.01e-06	GO:0048858	cell projection morphogenesis
1.17	1.14e-06	GO:0009058	biosynthetic process
1.14	1.29e-06	GO:0023052	signaling
1.13	1.48e-06	GO:0051716	cellular response to stimulus
1.17	1.52e-06	GO:0044267	cellular protein metabolic process
1.30	1.78e-06	GO:0031324	negative regulation of cellular metabolic process
1.41	1.93e-06	GO:0007417	central nervous system development
1.45	1.96e-06	GO:0007409	axonogenesis
1.61	2.09e-06	GO:0048011	nerve growth factor receptor signaling pathway
1.47	2.71e-06	GO:0048598	embryonic morphogenesis
1.34	2.72e-06	GO:0009890	negative regulation of biosynthetic process
1.26	2.95e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.36	3.05e-06	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.43	3.21e-06	GO:0048812	neuron projection morphogenesis
1.34	4.08e-06	GO:0031327	negative regulation of cellular biosynthetic process
1.36	4.12e-06	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15	4.86e-06	GO:0034641	cellular nitrogen compound metabolic process
1.34	5.01e-06	GO:0045595	regulation of cell differentiation
1.38	5.25e-06	GO:0051253	negative regulation of RNA metabolic process
1.36	6.44e-06	GO:0051172	negative regulation of nitrogen compound metabolic process
1.38	8.87e-06	GO:0045892	negative regulation of transcription, DNA-dependent
1.34	1.13e-05	GO:0010558	negative regulation of macromolecule biosynthetic process
1.28	1.48e-05	GO:0050793	regulation of developmental process
1.47	1.65e-05	GO:0007411	axon guidance
1.14	2.32e-05	GO:0006807	nitrogen compound metabolic process
1.15	3.10e-05	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	3.74e-05	GO:0006996	organelle organization
1.38	4.16e-05	GO:0031175	neuron projection development
1.30	4.50e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.13	5.52e-05	GO:0007165	signal transduction
1.32	6.12e-05	GO:0051254	positive regulation of RNA metabolic process
1.35	6.19e-05	GO:0048666	neuron development
1.30	6.27e-05	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13	6.29e-05	GO:0051179	localization
1.18	7.04e-05	GO:0048583	regulation of response to stimulus
1.32	8.41e-05	GO:0030030	cell projection organization
1.25	8.95e-05	GO:0010646	regulation of cell communication
1.46	9.15e-05	GO:0060284	regulation of cell development
1.27	1.03e-04	GO:0006351	transcription, DNA-dependent
1.25	1.03e-04	GO:0032268	regulation of cellular protein metabolic process
1.42	1.47e-04	GO:0007420	brain development
1.40	2.02e-04	GO:0007264	small GTPase mediated signal transduction
1.41	2.07e-04	GO:0009792	embryo development ending in birth or egg hatching
1.32	2.24e-04	GO:0051726	regulation of cell cycle
1.41	2.30e-04	GO:0051056	regulation of small GTPase mediated signal transduction
1.27	2.53e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.53	2.54e-04	GO:0045786	negative regulation of cell cycle
1.41	2.56e-04	GO:0043009	chordate embryonic development
1.52	2.65e-04	GO:0048568	embryonic organ development
1.28	2.73e-04	GO:0031399	regulation of protein modification process
1.24	3.89e-04	GO:0007049	cell cycle
1.27	4.11e-04	GO:0051128	regulation of cellular component organization
1.21	4.11e-04	GO:0051641	cellular localization
1.28	4.16e-04	GO:2000026	regulation of multicellular organismal development
1.20	4.25e-04	GO:0065009	regulation of molecular function
1.43	4.49e-04	GO:0071495	cellular response to endogenous stimulus
1.54	5.76e-04	GO:0045664	regulation of neuron differentiation
1.31	5.84e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.13	6.16e-04	GO:0051234	establishment of localization
1.29	6.88e-04	GO:0009719	response to endogenous stimulus
1.23	7.42e-04	GO:0051246	regulation of protein metabolic process
1.21	8.51e-04	GO:0051239	regulation of multicellular organismal process
1.23	1.22e-03	GO:0006793	phosphorus metabolic process
1.23	1.22e-03	GO:0006796	phosphate metabolic process
1.30	1.28e-03	GO:0009887	organ morphogenesis
1.25	1.30e-03	GO:0009891	positive regulation of biosynthetic process
1.13	1.58e-03	GO:0006810	transport
1.28	1.80e-03	GO:0010628	positive regulation of gene expression
1.26	2.21e-03	GO:0046907	intracellular transport
1.17	2.50e-03	GO:0034645	cellular macromolecule biosynthetic process
1.46	2.73e-03	GO:0050767	regulation of neurogenesis
1.36	3.23e-03	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.27	4.24e-03	GO:0019220	regulation of phosphate metabolic process
1.27	4.24e-03	GO:0051174	regulation of phosphorus metabolic process
1.26	5.14e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.17	5.29e-03	GO:0009059	macromolecule biosynthetic process
1.12	5.45e-03	GO:0019538	protein metabolic process
1.42	5.70e-03	GO:0051960	regulation of nervous system development
1.40	6.27e-03	GO:0032870	cellular response to hormone stimulus
1.43	6.37e-03	GO:0045596	negative regulation of cell differentiation
1.62	7.22e-03	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.22	7.29e-03	GO:0032774	RNA biosynthetic process
1.26	7.35e-03	GO:0006468	protein phosphorylation
1.60	1.07e-02	GO:0022604	regulation of cell morphogenesis
1.24	1.13e-02	GO:0033554	cellular response to stress
1.20	1.22e-02	GO:0051649	establishment of localization in cell
1.14	1.45e-02	GO:0090304	nucleic acid metabolic process
1.27	1.59e-02	GO:0001932	regulation of protein phosphorylation
1.31	1.64e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.38	1.66e-02	GO:0001501	skeletal system development
1.27	2.04e-02	GO:0009725	response to hormone stimulus
1.25	2.14e-02	GO:0042325	regulation of phosphorylation
1.15	2.84e-02	GO:0048513	organ development
1.21	3.08e-02	GO:0032879	regulation of localization
1.30	3.15e-02	GO:0045859	regulation of protein kinase activity
1.23	3.18e-02	GO:0022402	cell cycle process
1.41	3.24e-02	GO:0000165	MAPKKK cascade
1.41	3.24e-02	GO:0046578	regulation of Ras protein signal transduction
1.42	3.66e-02	GO:0051129	negative regulation of cellular component organization
1.35	3.75e-02	GO:0007389	pattern specification process
1.43	3.87e-02	GO:0071375	cellular response to peptide hormone stimulus
1.31	3.99e-02	GO:0023057	negative regulation of signaling
1.30	4.20e-02	GO:0048646	anatomical structure formation involved in morphogenesis
1.57	4.46e-02	GO:0010975	regulation of neuron projection development
1.35	4.52e-02	GO:0051098	regulation of binding
1.33	4.69e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.30	4.79e-02	GO:0010648	negative regulation of cell communication
1.36	4.83e-02	GO:0022603	regulation of anatomical structure morphogenesis

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.11	1.19e-45	GO:0005622	intracellular
1.12	1.36e-45	GO:0044424	intracellular part
1.16	6.90e-39	GO:0005737	cytoplasm
1.13	1.91e-28	GO:0043227	membrane-bounded organelle
1.13	3.88e-28	GO:0043231	intracellular membrane-bounded organelle
1.11	4.69e-27	GO:0043226	organelle
1.11	1.74e-26	GO:0043229	intracellular organelle
1.16	6.24e-19	GO:0044446	intracellular organelle part
1.15	2.08e-18	GO:0044444	cytoplasmic part
1.15	3.98e-18	GO:0005634	nucleus
1.15	6.28e-18	GO:0044422	organelle part
1.25	3.31e-14	GO:0044428	nuclear part
1.24	3.66e-12	GO:0005829	cytosol
1.04	3.83e-12	GO:0044464	cell part
1.04	4.32e-12	GO:0005623	cell
1.25	1.38e-11	GO:0031981	nuclear lumen
1.22	1.61e-11	GO:0070013	intracellular organelle lumen
1.21	1.88e-10	GO:0043233	organelle lumen
1.28	2.60e-10	GO:0005654	nucleoplasm
1.20	5.59e-10	GO:0031974	membrane-enclosed lumen
1.17	4.15e-06	GO:0031090	organelle membrane
1.30	1.02e-05	GO:0044451	nucleoplasm part
1.25	1.83e-05	GO:0005794	Golgi apparatus
1.19	4.72e-05	GO:0012505	endomembrane system
1.31	1.16e-04	GO:0044431	Golgi apparatus part
1.31	1.45e-03	GO:0000139	Golgi membrane
1.49	2.11e-03	GO:0031252	cell leading edge
1.11	2.39e-03	GO:0043234	protein complex
1.98	4.48e-03	GO:0017053	transcriptional repressor complex
1.52	4.89e-03	GO:0005912	adherens junction
1.23	1.35e-02	GO:0015630	microtubule cytoskeleton
1.20	1.61e-02	GO:0042995	cell projection
1.46	1.80e-02	GO:0070161	anchoring junction
1.67	1.80e-02	GO:0009898	internal side of plasma membrane
1.72	3.43e-02	GO:0031256	leading edge membrane
1.09	3.53e-02	GO:0032991	macromolecular complex
1.24	3.63e-02	GO:0005694	chromosome
1.33	4.64e-02	GO:0005874	microtubule

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	2.13e-22	GO:0005515	protein binding
1.07	7.64e-19	GO:0005488	binding
1.22	8.02e-08	GO:0016740	transferase activity
1.29	1.34e-07	GO:0001071	nucleic acid binding transcription factor activity
1.29	1.34e-07	GO:0003700	sequence-specific DNA binding transcription factor activity
1.31	1.82e-06	GO:0016301	kinase activity
1.27	2.74e-06	GO:0030528	transcription regulator activity
1.10	2.76e-06	GO:0003824	catalytic activity
1.17	3.57e-06	GO:0000166	nucleotide binding
1.30	5.49e-06	GO:0019899	enzyme binding
1.32	8.24e-06	GO:0043565	sequence-specific DNA binding
1.27	1.17e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.30	2.29e-05	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.37	2.52e-05	GO:0030695	GTPase regulator activity
1.36	4.05e-05	GO:0060589	nucleoside-triphosphatase regulator activity
1.16	4.11e-05	GO:0003677	DNA binding
1.17	4.30e-05	GO:0017076	purine nucleotide binding
1.17	4.67e-05	GO:0032553	ribonucleotide binding
1.17	4.67e-05	GO:0032555	purine ribonucleotide binding
1.37	6.18e-05	GO:0004674	protein serine/threonine kinase activity
1.17	8.83e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.29	5.18e-04	GO:0004672	protein kinase activity
1.41	6.09e-04	GO:0008134	transcription factor binding
1.34	8.03e-04	GO:0019904	protein domain specific binding
1.39	9.02e-04	GO:0016563	transcription activator activity
1.55	1.17e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.17	2.39e-03	GO:0030554	adenyl nucleotide binding
1.17	2.40e-03	GO:0032559	adenyl ribonucleotide binding
1.38	4.45e-03	GO:0005083	small GTPase regulator activity
1.16	5.19e-03	GO:0005524	ATP binding
1.20	1.03e-02	GO:0030234	enzyme regulator activity
1.38	1.11e-02	GO:0016881	acid-amino acid ligase activity
1.35	1.71e-02	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.31	1.88e-02	GO:0008047	enzyme activator activity
1.26	1.95e-02	GO:0008092	cytoskeletal protein binding
1.48	2.36e-02	GO:0004721	phosphoprotein phosphatase activity
1.10	2.41e-02	GO:0003676	nucleic acid binding
1.22	2.53e-02	GO:0042802	identical protein binding
1.39	3.33e-02	GO:0019787	small conjugating protein ligase activity
1.33	3.96e-02	GO:0016564	transcription repressor activity
1.39	4.92e-02	GO:0004842	ubiquitin-protein ligase activity