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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: TFAP4.p2

Z-value: 1.969

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_36451189	3.411	NM_030967	KRTAP1-3 KRTAP1-1	keratin associated protein 1-3 keratin associated protein 1-1
chr12_-_56157898	1.806	NM_001080156	ARHGAP9	Rho GTPase activating protein 9
chr9_+_133154896	1.710	NM_032728	PPAPDC3	phosphatidic acid phosphatase type 2 domain containing 3
chr22_-_20235372	1.458	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr9_+_139292094	1.421	NM_017723	C9orf167	chromosome 9 open reading frame 167
chr16_+_2461500	1.353	NM_006181	NTN3	netrin 3
chr12_-_107257205	1.329	NM_001142343 NM_001142344 NM_004072	CMKLR1	chemokine-like receptor 1
chr12_+_56135353	1.312	NM_031479	INHBE	inhibin, beta E
chr1_-_21868380	1.225	NM_001145657 NM_002885	RAP1GAP	RAP1 GTPase activating protein
chr22_+_20068039	1.197	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr12_+_52105131	1.190		AMHR2	anti-Mullerian hormone receptor, type II
chr21_-_44836811	1.180	NM_198688	KRTAP10-6	keratin associated protein 10-6
chr22_+_21393107	1.155		IGLJ3	immunoglobulin lambda joining 3
chr14_-_22354457	1.152		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_-_47427263	1.086	NM_005055 NM_032645	RAPSN	receptor-associated protein of the synapse
chr16_+_73810383	1.062	NM_001906	CTRB1 CTRB2	chymotrypsinogen B1 chymotrypsinogen B2
chr17_-_36444626	1.029	NM_030966	KRTAP1-3	keratin associated protein 1-3
chr1_+_179164195	1.027
chr14_-_22354389	1.013		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr8_-_38127489	1.012	NM_000349	STAR	steroidogenic acute regulatory protein
chr22_+_21094094	0.983
chr7_+_100037817	0.974	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr6_+_43565192	0.944	NM_001146017	TJAP1	tight junction associated protein 1 (peripheral)
chr17_+_53769659	0.940		LOC100506779	hypothetical LOC100506779
chr11_-_65395248	0.920		EFEMP2	EGF containing fibulin-like extracellular matrix protein 2
chr11_+_74629597	0.917	NM_001195528	LOC441617	hypothetical LOC441617
chr11_+_67567022	0.915	NM_006053	TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr19_-_54350457	0.902	NM_002152	HRC	histidine rich calcium binding protein
chr20_-_3635774	0.897	NM_023068	SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin
chr15_-_63502438	0.895	NM_020962	IGDCC4	immunoglobulin superfamily, DCC subclass, member 4
chr22_-_49311439	0.888	NM_001169110	SCO2	SCO cytochrome oxidase deficient homolog 2 (yeast)
chr1_-_6585268	0.884		KLHL21	kelch-like 21 (Drosophila)
chr1_-_39871226	0.876		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr17_-_36436979	0.864	NM_031957	KRTAP1-5	keratin associated protein 1-5
chr1_-_20014180	0.863	NM_019062	RNF186	ring finger protein 186
chr5_+_176726918	0.838		RGS14	regulator of G-protein signaling 14
chr1_-_26266571	0.834	NM_032588	TRIM63	tripartite motif containing 63
chr14_+_102672745	0.829		TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr7_+_149657810	0.806	NM_138434	C7orf29	chromosome 7 open reading frame 29
chr20_+_23419765	0.785	NM_005492	CST8	cystatin 8 (cystatin-related epididymal specific)
chr16_+_30293598	0.784	NM_013292	MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle
chr5_+_150020595	0.782	NM_001122853 NM_133371	MYOZ3	myozenin 3
chr8_-_145187553	0.780	NM_017570	OPLAH	5-oxoprolinase (ATP-hydrolysing)
chr6_+_31799099	0.769	NM_025260 NM_138272 NM_138273 NM_138274 NM_138275 NM_138277	C6orf25	chromosome 6 open reading frame 25
chr1_+_110012166	0.769	NM_000848 NM_001142368	GSTM2	glutathione S-transferase mu 2 (muscle)
chr2_+_220007943	0.768	NM_005876	SPEG	SPEG complex locus
chr1_-_16217025	0.757		HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)
chr1_-_218168137	0.755		SLC30A10	solute carrier family 30, member 10
chr11_+_63730720	0.754	NM_031471 NM_178443	FERMT3	fermitin family member 3
chr17_+_77453363	0.740	NM_148896	NPB	neuropeptide B
chr21_+_44844924	0.734	NM_198689	KRTAP10-7	keratin associated protein 10-7
chr12_-_107551744	0.731		SELPLG	selectin P ligand
chr16_+_28797309	0.729	NM_004320 NM_173201	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr19_+_11510578	0.725	NM_001299	CNN1	calponin 1, basic, smooth muscle
chr20_+_24877904	0.724		CST7	cystatin F (leukocystatin)
chr11_+_71580816	0.713	NM_016729	FOLR1	folate receptor 1 (adult)
chr12_-_107551783	0.709	NM_003006	SELPLG	selectin P ligand
chr1_-_155095289	0.706	NM_014215	INSRR	insulin receptor-related receptor
chr14_+_102636233	0.703	NM_001077594	EXOC3L4	exocyst complex component 3-like 4
chr1_-_1525309	0.696		LOC643988	hypothetical LOC643988
chr16_+_620932	0.687	NM_053284	WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1
chr16_+_68765428	0.684	NM_173619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr3_-_51971915	0.683	NM_033010	PCBP4	poly(rC) binding protein 4
chr16_-_1215254	0.681	NM_012467	TPSG1	tryptase gamma 1
chr17_+_25910709	0.661	NM_015594	TBC1D29	TBC1 domain family, member 29
chr10_+_134108643	0.659	NM_173541	C10orf91	chromosome 10 open reading frame 91
chr13_+_112704077	0.659		MCF2L	MCF.2 cell line derived transforming sequence-like
chr6_+_37245860	0.656	NM_002648	PIM1	pim-1 oncogene
chr17_+_78286687	0.655	NM_022158	FN3K	fructosamine 3 kinase
chr3_-_13032130	0.647
chr5_-_176869148	0.644
chr1_+_26220852	0.641	NM_004455	EXTL1	exostoses (multiple)-like 1
chr13_+_112704028	0.635		MCF2L	MCF.2 cell line derived transforming sequence-like
chr15_-_35180656	0.627	NM_002399	MEIS2	Meis homeobox 2
chr11_+_70915960	0.626	NM_001012503	KRTAP5-7	keratin associated protein 5-7
chr7_-_127833231	0.620	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr9_-_138958889	0.607		FBXW5	F-box and WD repeat domain containing 5
chr20_+_61838479	0.605		LIME1	Lck interacting transmembrane adaptor 1
chr17_+_38256886	0.604
chr6_-_32184975	0.596	NM_019105	TNXB	tenascin XB
chr19_-_14030970	0.596	NM_001145028	PALM3	paralemmin 3
chr21_+_42697058	0.595	NM_001001895 NM_018961	UBASH3A	ubiquitin associated and SH3 domain containing A
chr17_-_17050355	0.593	NM_178836	PLD6	phospholipase D family, member 6
chr11_+_384238	0.592		PKP3	plakophilin 3
chr6_-_15771077	0.590		DTNBP1	dystrobrevin binding protein 1
chr19_-_45022993	0.583		FBL	fibrillarin
chr19_-_55156118	0.580	NM_001135163 NM_052884	SIGLEC11	sialic acid binding Ig-like lectin 11
chr17_+_76549658	0.580		RPTOR	regulatory associated protein of MTOR, complex 1
chr1_+_238321794	0.576	NM_020066	FMN2	formin 2
chr1_+_26220895	0.575		EXTL1	exostoses (multiple)-like 1
chr3_-_12175339	0.573		TIMP4	TIMP metallopeptidase inhibitor 4
chr13_+_112704051	0.573		MCF2L	MCF.2 cell line derived transforming sequence-like
chr3_-_10027770	0.572	NM_001008737	LOC401052	hypothetical LOC401052
chr19_+_60691671	0.572	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr8_-_145085616	0.569	NM_201384	PLEC	plectin
chr16_-_83703496	0.569	NM_198491	FAM92B	family with sequence similarity 92, member B
chr3_-_195553297	0.567	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr4_-_1827475	0.565	NM_012318	LETM1	leucine zipper-EF-hand containing transmembrane protein 1
chr11_-_66945190	0.563		PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme
chr3_-_52844274	0.560	NM_205853	MUSTN1	musculoskeletal, embryonic nuclear protein 1
chr10_+_88418147	0.551	NM_001171610	LDB3	LIM domain binding 3
chr17_+_38256710	0.550	NM_003734	AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr14_-_99140195	0.550	NM_001144995	CCDC85C	coiled-coil domain containing 85C
chr16_-_87405817	0.548	NM_000485 NM_001030018	APRT	adenine phosphoribosyltransferase
chr1_-_114855200	0.547		TRIM33	tripartite motif containing 33
chr16_+_170334	0.543	NM_005331	HBQ1	hemoglobin, theta 1
chr20_+_61838389	0.541	NM_017806	LIME1	Lck interacting transmembrane adaptor 1
chr1_-_218168404	0.541
chr15_+_61676604	0.540	NM_203373	FBXL22	F-box and leucine-rich repeat protein 22
chr6_-_15771239	0.539	NM_032122 NM_183040	DTNBP1	dystrobrevin binding protein 1
chr2_-_74634569	0.534	NM_032603	LOXL3	lysyl oxidase-like 3
chr18_+_9875722	0.534	NM_001098529 NM_032243	TXNDC2	thioredoxin domain containing 2 (spermatozoa)
chr16_+_68542310	0.529	NM_182619	CLEC18C CLEC18A CLEC18B	C-type lectin domain family 18, member C C-type lectin domain family 18, member A C-type lectin domain family 18, member B
chr9_-_139183675	0.527
chr1_-_33110668	0.527	NM_001171941	FNDC5	fibronectin type III domain containing 5
chr7_+_73341640	0.525	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr1_-_20122638	0.524	NM_014589	PLA2G2E	phospholipase A2, group IIE
chr20_-_61639104	0.524	NM_005975	PTK6	PTK6 protein tyrosine kinase 6
chr5_-_176869440	0.523		DOK3	docking protein 3
chr1_+_44870223	0.522		RNF220	ring finger protein 220
chr5_-_176869463	0.521	NM_024872	DOK3	docking protein 3
chr22_+_19649417	0.519	NM_001018060 NM_144704	AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr1_-_114855281	0.519	NM_015906 NM_033020	TRIM33	tripartite motif containing 33
chr19_-_60350122	0.519		TNNT1	troponin T type 1 (skeletal, slow)
chr10_+_88418243	0.510	NM_001080116 NM_001080114 NM_001080115 NM_001171611 NM_007078	LDB3	LIM domain binding 3
chr7_+_44045202	0.508		FLJ35390	hypothetical LOC255031
chr11_-_66961709	0.506	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr17_-_3651236	0.505	NM_002208	ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
chr7_-_75280962	0.504	NM_002991	CCL24	chemokine (C-C motif) ligand 24
chr9_+_114671635	0.502		SNX30	sorting nexin family member 30
chr17_-_17050326	0.502		PLD6	phospholipase D family, member 6
chr1_+_54132447	0.502	NM_000792 NM_001039715 NM_001039716 NM_213593	DIO1	deiodinase, iodothyronine, type I
chr3_-_18441763	0.499	NM_001195470 NM_002971	SATB1	SATB homeobox 1
chr8_-_145640579	0.497		TONSL	tonsoku-like, DNA repair protein
chr14_-_22354851	0.497	NM_001126105 NM_003982	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr1_-_39877928	0.495	NM_014571	HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr19_+_52469939	0.494	NM_178511	PRR24	proline rich 24
chr6_-_53638464	0.493	NM_001003760	KLHL31	kelch-like 31 (Drosophila)
chr6_+_1556543	0.487		FOXC1	forkhead box C1
chr12_+_112344529	0.485	NM_138432	SDSL	serine dehydratase-like
chr20_-_61669550	0.482	NM_033405	PRIC285	peroxisomal proliferator-activated receptor A interacting complex 285
chr22_+_21116283	0.480
chr2_+_94900904	0.480	NM_144705	TEKT4	tektin 4
chr8_-_145099963	0.473	NM_201379	PLEC	plectin
chr9_-_139042416	0.473		ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2
chr1_+_159959072	0.473	NM_001002901	FCRLB	Fc receptor-like B
chr16_-_65984836	0.472	NM_015964 NM_016140	TPPP3	tubulin polymerization-promoting protein family member 3
chr22_+_20326615	0.465		SDF2L1	stromal cell-derived factor 2-like 1
chr17_-_40839082	0.461	NM_001159330	ARHGAP27	Rho GTPase activating protein 27
chr15_-_72922577	0.460	NM_001099436	ULK3	unc-51-like kinase 3 (C. elegans)
chr22_-_25344037	0.460		CRYBB1	crystallin, beta B1
chr16_-_86460529	0.459	NM_003486	SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
chr3_-_13436802	0.459	NM_024923	NUP210	nucleoporin 210kDa
chr1_-_21821597	0.457		RAP1GAP	RAP1 GTPase activating protein
chr1_-_225572419	0.454	NM_003607 NM_014826	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)
chr20_-_46877689	0.453		PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr2_+_3620296	0.451	NM_024027 NM_199235	COLEC11	collectin sub-family member 11
chr16_+_155972	0.451	NM_001003938	HBM	hemoglobin, mu
chr6_-_154873480	0.450		CNKSR3	CNKSR family member 3
chr6_+_43151922	0.449	NM_002821 NM_152880 NM_152881 NM_152882	PTK7	PTK7 protein tyrosine kinase 7
chr12_+_62523648	0.449
chr16_+_30903963	0.447	NM_001142777 NM_001142778 NM_025193	HSD3B7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr20_-_48203709	0.445	NM_001162505 NM_199129 NM_199203	TMEM189 TMEM189-UBE2V1	transmembrane protein 189 TMEM189-UBE2V1 readthrough
chr7_-_156495985	0.444	NM_005515	MNX1	motor neuron and pancreas homeobox 1
chr15_+_72253940	0.444	NM_201526	ISLR	immunoglobulin superfamily containing leucine-rich repeat
chr11_-_75599433	0.443		WNT11	wingless-type MMTV integration site family, member 11
chr4_-_5071996	0.443	NM_018659	CYTL1	cytokine-like 1
chr12_+_120548831	0.439	NM_032790	ORAI1	ORAI calcium release-activated calcium modulator 1
chr21_+_42946719	0.439	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr1_-_39877883	0.439		HEYL	hairy/enhancer-of-split related with YRPW motif-like
chr9_+_115265827	0.438	NM_017790	RGS3	regulator of G-protein signaling 3
chr14_+_102659464	0.437		TNFAIP2	tumor necrosis factor, alpha-induced protein 2
chr14_+_94160046	0.436
chr8_+_21968375	0.435		EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr22_+_19651446	0.435	NM_001146288	AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3
chr16_+_65436341	0.435	NM_001014435	CA7	carbonic anhydrase VII
chr1_+_23994914	0.435
chr20_-_34841107	0.434		KIAA0889	KIAA0889
chr17_-_3447084	0.433	NM_018727	TRPV1	transient receptor potential cation channel, subfamily V, member 1
chr22_+_17539198	0.431
chr8_+_21968273	0.431	NM_001114136 NM_001114139	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr2_+_43919606	0.429	NM_022437	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8
chr14_+_20595820	0.429	NM_138331	RNASE8	ribonuclease, RNase A family, 8
chr10_-_75085754	0.428	NM_001114133	SYNPO2L	synaptopodin 2-like
chr1_-_229058404	0.428	NM_001136495	C1orf198	chromosome 1 open reading frame 198
chr1_-_46789473	0.428	NM_001097611	KNCN	kinocilin
chr3_+_50279993	0.427	NM_001005914 NM_004636	SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr19_-_43919428	0.426		CAPN12	calpain 12
chr12_+_54361685	0.426		METTL7B	methyltransferase like 7B
chr2_+_171381626	0.426		GAD1	glutamate decarboxylase 1 (brain, 67kDa)
chr19_+_61379200	0.425	NM_001145546 NM_033106	GALP	galanin-like peptide
chr4_-_6253152	0.425	NM_001099433 NM_144720	JAKMIP1	janus kinase and microtubule interacting protein 1
chr7_-_150847698	0.423		RHEB	Ras homolog enriched in brain
chr16_-_31013626	0.422	NM_024006 NM_206824	VKORC1	vitamin K epoxide reductase complex, subunit 1
chr15_-_72922533	0.422		ULK3	unc-51-like kinase 3 (C. elegans)
chr16_+_4370879	0.421		VASN	vasorin
chr19_-_59438411	0.420	NM_024318	LILRB3 LILRA6	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr20_+_31783426	0.420	NM_032819	ZNF341	zinc finger protein 341
chr3_-_49374973	0.420		RHOA	ras homolog gene family, member A
chr14_+_99859427	0.419	NM_207117	SLC25A47	solute carrier family 25, member 47

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.19	6.50e-04	GO:0023052	signaling
1.10	1.43e-03	GO:0065007	biological regulation
1.10	1.37e-02	GO:0050789	regulation of biological process
1.17	3.00e-02	GO:0007165	signal transduction

Nothing significant found in compartment category.

Nothing significant found in function category.