Motif ID: TFEB.p2

Z-value: 0.971


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41811916-0.185.1e-01Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_160310118 1.570 NM_000876
 IGF2R
insulin-like growth factor 2 receptor
chr11_-_85457753 1.472 NM_001008660
NM_007166
 PICALM

phosphatidylinositol binding clathrin assembly protein

chr1_-_26266571 1.472 NM_032588
 TRIM63
tripartite motif containing 63
chr12_-_56432377 1.313 CDK4
cyclin-dependent kinase 4
chr11_-_85457736 1.289 PICALM
phosphatidylinositol binding clathrin assembly protein
chr10_+_69314347 1.265 NM_012238
 SIRT1
sirtuin 1
chr12_-_56432375 1.177 CDK4
cyclin-dependent kinase 4
chr7_-_130443379 1.143 FLJ43663
hypothetical LOC378805
chr12_-_56432385 1.110 NM_000075
 CDK4
cyclin-dependent kinase 4
chr6_+_87921980 1.017 NM_015021
 ZNF292
zinc finger protein 292
chr15_-_71712711 0.970 NM_001161363
NM_001161364
NM_012428
NM_017455
 NPTN



neuroplastin



chr5_+_172415891 0.949 NM_001168393
NM_001168394
NM_153607
 C5orf41


chromosome 5 open reading frame 41


chr1_+_11788889 0.933 CLCN6
chloride channel 6
chr11_-_71492019 0.897 NM_017907
 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr12_-_56432292 0.887 CDK4
cyclin-dependent kinase 4
chr19_+_10626106 0.870 ILF3
interleukin enhancer binding factor 3, 90kDa
chr22_-_19543069 0.866 NM_058004
 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr1_+_11788827 0.860 CLCN6
chloride channel 6
chr1_-_152797760 0.856 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr1_-_26105477 0.848 NM_001145454
NM_005563
 STMN1

stathmin 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
8.37 4.54e-05 GO:0007040 lysosome organization
6.42 9.25e-06 GO:0007033 vacuole organization
1.72 2.70e-03 GO:0008104 protein localization
1.68 6.61e-04 GO:0033036 macromolecule localization
1.63 5.15e-03 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
8.22 8.05e-04 GO:0033176 proton-transporting V-type ATPase complex
4.39 1.53e-05 GO:0042470 melanosome
4.39 1.53e-05 GO:0048770 pigment granule
4.11 1.14e-08 GO:0005774 vacuolar membrane
3.93 3.75e-08 GO:0044437 vacuolar part
3.59 6.90e-14 GO:0005773 vacuole
3.57 2.35e-04 GO:0005765 lysosomal membrane
3.29 3.10e-09 GO:0000323 lytic vacuole
3.29 3.10e-09 GO:0005764 lysosome
3.28 1.71e-04 GO:0005769 early endosome
2.99 1.81e-02 GO:0005770 late endosome
2.49 1.51e-03 GO:0010008 endosome membrane
2.47 1.78e-03 GO:0044440 endosomal part
2.25 6.99e-05 GO:0005768 endosome
1.75 5.00e-03 GO:0031410 cytoplasmic vesicle
1.72 7.06e-03 GO:0031982 vesicle
1.71 2.12e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.68 3.52e-02 GO:0031988 membrane-bounded vesicle
1.42 3.87e-03 GO:0031090 organelle membrane
1.38 2.18e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.36 3.22e-02 GO:0003713 transcription coactivator activity
1.23 1.74e-05 GO:0005515 protein binding