Motif ID: bHLH_family.p2

Z-value: 1.955


Transcription factors associated with bHLH_family.p2:

Gene SymbolEntrez IDGene Name
ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 56938 aryl hydrocarbon receptor nuclear translocator-like 2
CLOCK 9575 clock homolog (mouse)
HES6 55502 hairy and enhancer of split 6 (Drosophila)
HEY1 23462 hairy/enhancer-of-split related with YRPW motif 1
HEY2 23493 hairy/enhancer-of-split related with YRPW motif 2
HEYL 26508 hairy/enhancer-of-split related with YRPW motif-like
ID1 3397 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MITF 4286 microphthalmia-associated transcription factor
MLXIPL 51085 MLX interacting protein-like
MNT 4335 MAX binding protein
MXD3 83463 MAX dimerization protein 3
MXD4 10608 MAX dimerization protein 4
MXI1 4601 MAX interactor 1
NPAS2 4862 neuronal PAS domain protein 2
OLIG1 116448 oligodendrocyte transcription factor 1
OLIG2 10215 oligodendrocyte lineage transcription factor 2
TFE3 7030 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NPAS2chr2_+_1008029230.722.5e-03Click!
TFE3chrX_-_48787696-0.712.9e-03Click!
ARNTLchr11_+_132559520.703.8e-03Click!
CLOCKchr4_-_56107725-0.582.3e-02Click!
HES6chr2_-_2388133650.562.8e-02Click!
MXD4chr4_-_22335040.534.2e-02Click!
ARNTL2chr12_+_273770340.524.7e-02Click!
HEYLchr1_-_39877883-0.459.0e-02Click!
MXI1chr10_+_1119599780.391.6e-01Click!
MNTchr17_-_22509670.381.6e-01Click!
MITFchr3_+_69895651-0.361.9e-01Click!
OLIG1chr21_+_333658740.302.7e-01Click!
MXD3chr5_-_1766718970.283.1e-01Click!
OLIG2chr21_+_333200800.283.1e-01Click!
HEY2chr6_+_126112417-0.263.5e-01Click!
MLXIPLchr7_-_72676750-0.214.5e-01Click!
ID1chr20_+_296567440.156.0e-01Click!
HEY1chr8_-_808424520.039.1e-01Click!


Activity profile for motif bHLH_family.p2.

activity profile for motif bHLH_family.p2


Sorted Z-values histogram for motif bHLH_family.p2

Sorted Z-values for motif bHLH_family.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of bHLH_family.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_54660954 3.308 NM_133267
GSX2
GS homeobox 2
chr8_+_120289735 2.813 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr7_-_27162688 2.655 NM_006896
HOXA7
homeobox A7
chr12_-_47604930 2.535 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr17_-_36469869 2.493 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr7_-_1562272 2.461 NM_001097620
TMEM184A
transmembrane protein 184A
chr2_-_219826854 2.350 NM_006000
TUBA4A
tubulin, alpha 4a
chr16_-_66827449 2.274 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr4_-_17392232 2.208 NM_015688
FAM184B
family with sequence similarity 184, member B
chr12_-_50871953 2.195 NM_001081492
NM_182507
KRT80

keratin 80

chr17_+_36515166 2.153 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr11_+_126378507 2.138 NCRNA00288
non-protein coding RNA 288
chr3_-_11585264 2.118 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr9_+_696744 2.115 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr1_+_201364050 2.104 ADORA1
adenosine A1 receptor
chr2_-_217267742 2.090 IGFBP5
insulin-like growth factor binding protein 5
chr19_+_1226510 1.967 NM_017914
C19orf24
chromosome 19 open reading frame 24
chrX_-_114703273 1.953


chr16_+_639278 1.942 NM_145294
WDR90
WD repeat domain 90
chr2_-_133144094 1.892 LYPD1
LY6/PLAUR domain containing 1
chr11_-_116168316 1.823 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr6_-_18230829 1.819 NM_198586
NHLRC1
NHL repeat containing 1
chr2_-_219633481 1.817 NM_002181
IHH
Indian hedgehog
chr16_+_84204424 1.805 NM_014615
KIAA0182
KIAA0182
chr3_-_126414252 1.787 NM_024628
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr13_+_112999538 1.776 LAMP1
lysosomal-associated membrane protein 1
chr10_+_112826774 1.747 NM_000681
ADRA2A
adrenergic, alpha-2A-, receptor
chr9_-_129869211 1.739 NM_197956
NAIF1
nuclear apoptosis inducing factor 1
chr22_+_34107087 1.729 HMOX1
heme oxygenase (decycling) 1
chr3_-_49370755 1.721 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr19_-_10625449 1.710 LOC147727
hypothetical LOC147727
chr8_-_75396016 1.698 NM_020647
JPH1
junctophilin 1
chr11_+_66915997 1.686 NM_004584
RAD9A
RAD9 homolog A (S. pombe)
chr12_+_6703686 1.644 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr2_+_176680251 1.626 NM_021192
HOXD11
homeobox D11
chr17_-_17050326 1.623 PLD6
phospholipase D family, member 6
chr3_-_49370682 1.613 GPX1
glutathione peroxidase 1
chr3_+_49034494 1.595 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chrX_+_55760774 1.573 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr8_+_22492198 1.568 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr14_-_19999475 1.557 NM_001100814
NM_144568
TMEM55B

transmembrane protein 55B

chr11_+_7491789 1.557 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_-_19599973 1.544 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr17_-_17050355 1.538 NM_178836
PLD6
phospholipase D family, member 6
chr17_-_36507900 1.536 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr10_+_101079099 1.533 CNNM1
cyclin M1
chrX_-_107866262 1.532 NM_003604
IRS4
insulin receptor substrate 4
chr13_+_112999462 1.521 NM_005561
LAMP1
lysosomal-associated membrane protein 1
chr11_+_7491576 1.497 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_+_176761552 1.445 NM_024501
HOXD1
homeobox D1
chr20_-_43953036 1.422 NM_080749
NEURL2
neuralized homolog 2 (Drosophila)
chr9_+_17124974 1.392 NM_001114395
NM_017738
CNTLN

centlein, centrosomal protein

chr1_-_152459506 1.376 C1orf43
chromosome 1 open reading frame 43
chr4_-_15694407 1.361 PROM1
prominin 1
chr1_-_152459667 1.337 C1orf43
chromosome 1 open reading frame 43
chr20_+_43952997 1.337 NM_000308
NM_001127695
NM_001167594
CTSA


cathepsin A


chr10_-_91285290 1.331 NM_213606
SLC16A12
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr16_-_52876390 1.313 IRX3
iroquois homeobox 3
chr20_+_46971618 1.279 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr7_-_27149750 1.268 NM_019102
HOXA5
homeobox A5
chr2_-_154043403 1.260 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr17_-_29930431 1.254 NM_207454
C17orf102
chromosome 17 open reading frame 102
chr17_-_71362971 1.253 NM_012478
WBP2
WW domain binding protein 2
chr3_+_139636104 1.237 NM_031913
ESYT3
extended synaptotagmin-like protein 3
chr22_-_49317408 1.229 ODF3B
outer dense fiber of sperm tails 3B
chr6_+_96570565 1.212 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr18_+_17076166 1.206 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr2_+_215885063 1.195 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_-_133144950 1.195 NM_144586
LYPD1
LY6/PLAUR domain containing 1
chr1_+_148137778 1.180 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr20_+_37024383 1.157 NM_001190809
NM_021931
DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr10_+_101078784 1.156 NM_020348
CNNM1
cyclin M1
chr16_-_65742323 1.149 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr12_+_6703549 1.148 COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr3_+_139636111 1.148 ESYT3
extended synaptotagmin-like protein 3
chr13_+_27392136 1.144 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr3_-_172109119 1.137 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr17_+_7416780 1.120 NM_001416
EIF4A1
eukaryotic translation initiation factor 4A1
chr8_-_109165012 1.111 NM_178565
RSPO2
R-spondin 2 homolog (Xenopus laevis)
chr20_-_2769245 1.109 NM_022760
FAM113A
family with sequence similarity 113, member A
chr2_-_11727705 1.105 NM_012344
NTSR2
neurotensin receptor 2
chr17_-_4405367 1.098 NM_001105538
NM_014520
MYBBP1A

MYB binding protein (P160) 1a

chr3_-_50304706 1.096 NM_006764
IFRD2
interferon-related developmental regulator 2
chr22_-_42619139 1.094 NM_001177675
NM_138814
PNPLA5

patatin-like phospholipase domain containing 5

chr1_+_152459918 1.092 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chr17_-_74433048 1.091 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr20_+_18066473 1.086 NM_001164811
PET117
cytochrome c oxidase assembly factor-like
chr3_-_50335113 1.075 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr17_-_7078399 1.068 DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr6_-_80713589 1.053 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr1_+_222870573 1.044 CNIH3
cornichon homolog 3 (Drosophila)
chr1_+_148521852 1.023 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr12_+_6703525 1.023 COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr5_+_80292213 1.023 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr8_+_32525269 1.018 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr7_-_47588652 1.008 TNS3
tensin 3
chr3_+_98016114 1.005 NM_001080448
EPHA6
EPH receptor A6
chr5_+_94981735 1.000 NM_199243
GPR150
G protein-coupled receptor 150
chr16_+_29374479 1.000 NM_001017389
NM_003166
SULT1A4
SULT1A3
SLX1B
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr17_-_7078446 1.000 NM_004422
DVL2
dishevelled, dsh homolog 2 (Drosophila)
chr16_+_57106883 0.996 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr6_-_42218692 0.995 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr10_-_14090459 0.984 FRMD4A
FERM domain containing 4A
chr1_-_152459697 0.984 NM_001098616
NM_015449
NM_138740
C1orf43


chromosome 1 open reading frame 43


chr2_+_215885053 0.981 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr5_+_80292313 0.968 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr20_-_2769120 0.962 FAM113A
family with sequence similarity 113, member A
chr22_+_48740432 0.959 PIM3
pim-3 oncogene
chr2_+_215884923 0.958 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr20_+_43953372 0.956 CTSA
cathepsin A
chr17_-_68769613 0.953 NM_001129885
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr21_+_36993302 0.952


chr14_-_67051773 0.947 NM_182526
TMEM229B
transmembrane protein 229B
chr16_+_2510323 0.945 NM_001145815
NM_015944
AMDHD2

amidohydrolase domain containing 2

chr8_-_121893468 0.944 NM_021021
SNTB1
syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
chr16_-_69277355 0.941 NM_138383
MTSS1L
metastasis suppressor 1-like
chr7_-_23476497 0.935 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr12_+_32546243 0.935 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_-_92721633 0.933 GFI1
growth factor independent 1 transcription repressor
chr7_-_84654106 0.930 SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr6_-_46566969 0.929 RCAN2
regulator of calcineurin 2
chr17_-_2561676 0.926 NM_015229
KIAA0664
KIAA0664
chr13_-_19665036 0.926 GJB2
gap junction protein, beta 2, 26kDa
chr4_+_146820805 0.925 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr17_+_4434582 0.923 NM_001114974
SMTNL2
smoothelin-like 2
chr17_-_2250967 0.916 NM_020310
MNT
MAX binding protein
chr2_-_139254273 0.916 NM_007226
NXPH2
neurexophilin 2
chr11_-_106394039 0.915 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr9_-_34038869 0.914 UBAP2
ubiquitin associated protein 2
chr14_+_23575460 0.912 NM_001082488
DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 1
chr10_-_120504267 0.905


chr8_-_99375739 0.904 NM_024759
NIPAL2
NIPA-like domain containing 2
chrX_+_102749489 0.903 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr14_-_23981493 0.896 NM_020195
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr1_+_95058488 0.895 NM_001114106
SLC44A3
solute carrier family 44, member 3
chr17_-_18848713 0.894 NM_001039999
FAM83G
family with sequence similarity 83, member G
chr17_+_74542066 0.893 NM_198593
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr20_+_43953331 0.888 CTSA
cathepsin A
chr3_-_69064364 0.886 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr19_+_60688349 0.886 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr14_+_104226769 0.883 NM_001031714
NM_022489
NM_032714
INF2


inverted formin, FH2 and WH2 domain containing


chr15_-_98699628 0.879 NM_139057
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr7_+_55054416 0.878 EGFR
epidermal growth factor receptor
chr13_+_112999590 0.878 LAMP1
lysosomal-associated membrane protein 1
chr19_-_40938251 0.876 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr20_+_61054443 0.876 NM_022082
SLC17A9
solute carrier family 17, member 9
chr2_+_74594093 0.874 TLX2
T-cell leukemia homeobox 2
chr3_+_51992339 0.874 NM_000666
NM_001198895
NM_001198896
NM_001198897
NM_001198898
ACY1




aminoacylase 1




chr9_+_115265827 0.865 NM_017790
RGS3
regulator of G-protein signaling 3
chr12_-_47605478 0.858 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr7_-_11838260 0.855 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr17_+_36493927 0.854 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr1_-_20931288 0.849 SH2D5
SH2 domain containing 5
chr2_-_133145539 0.849 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr12_+_48641545 0.847 NM_001651
AQP5
aquaporin 5
chr7_-_45927263 0.843 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr2_+_217206327 0.842 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr14_-_19999324 0.839 TMEM55B
transmembrane protein 55B
chr19_+_748444 0.835 PTBP1
polypyrimidine tract binding protein 1
chr17_+_77529070 0.829 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr14_+_64240902 0.829 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_-_131919896 0.827 HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr20_+_43953428 0.824 CTSA
cathepsin A
chr2_-_216944911 0.818 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr17_-_74487527 0.818 NM_005567
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
chr1_+_150937463 0.817 NM_178428
LCE2A
late cornified envelope 2A
chr8_+_22492586 0.817 PDLIM2
PDZ and LIM domain 2 (mystique)
chr2_+_223625105 0.816 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr14_-_76807302 0.809 NM_021257
NGB
neuroglobin
chr17_-_40866062 0.807 NM_174919
SH3D20
SH3 domain containing 20
chr14_-_63830830 0.806 NM_001040275
NM_001437
ESR2

estrogen receptor 2 (ER beta)

chr16_+_65790514 0.806 NM_024712
ELMO3
engulfment and cell motility 3
chr6_-_33822659 0.801 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr19_+_10673105 0.796 NM_031209
QTRT1
queuine tRNA-ribosyltransferase 1
chr12_+_52806103 0.795 LOC400043
hypothetical LOC400043
chr10_-_104463947 0.795 NM_004311
ARL3
ADP-ribosylation factor-like 3
chr7_-_27136876 0.793 NM_002141
HOXA4
homeobox A4
chr6_+_37245860 0.792 NM_002648
PIM1
pim-1 oncogene
chr19_-_40938046 0.792 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr1_+_45565126 0.788 NM_032756
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr7_-_72822471 0.788 NM_001306
CLDN3
claudin 3
chr5_+_63838183 0.788 NM_001029875
RGS7BP
regulator of G-protein signaling 7 binding protein
chr3_-_172109075 0.787 EIF5A2
eukaryotic translation initiation factor 5A2
chr17_-_77478835 0.785 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr15_+_38082041 0.783 EIF2AK4
eukaryotic translation initiation factor 2 alpha kinase 4
chr17_+_21131940 0.782 NM_002756
MAP2K3
mitogen-activated protein kinase kinase 3
chr10_+_52421120 0.778 PRKG1
protein kinase, cGMP-dependent, type I
chr3_+_49482474 0.771 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr20_+_61796731 0.768 NM_032945
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr5_-_94646033 0.767 NM_024717
MCTP1
multiple C2 domains, transmembrane 1
chr17_-_76064842 0.762 NM_002522
NPTX1
neuronal pentraxin I
chr2_-_232037308 0.761 NM_005381
NCL
nucleolin
chr19_+_748390 0.761 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr18_-_72973750 0.760 NM_001025100
NM_001025101
MBP

myelin basic protein

chr22_+_34107051 0.759 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr16_+_51646292 0.757 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr9_+_132309914 0.757 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr12_-_57600564 0.755 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr5_+_122452739 0.754 NM_001136239
PRDM6
PR domain containing 6
chr4_+_8251818 0.751 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 4.34e-11 GO:0009987 cellular process
1.29 1.13e-09 GO:0048731 system development
1.27 1.26e-09 GO:0048856 anatomical structure development
1.25 7.80e-09 GO:0007275 multicellular organismal development
1.23 2.25e-08 GO:0032502 developmental process
1.36 1.15e-06 GO:0007399 nervous system development
1.29 5.26e-06 GO:0030154 cell differentiation
1.28 9.68e-06 GO:0048869 cellular developmental process
1.44 2.05e-05 GO:0048468 cell development
1.32 7.74e-05 GO:0009653 anatomical structure morphogenesis
1.38 1.44e-03 GO:0022008 neurogenesis
1.25 1.77e-03 GO:0048513 organ development
1.52 3.13e-03 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.62 3.49e-03 GO:0007411 axon guidance
1.39 3.96e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.37 5.20e-03 GO:0048699 generation of neurons
1.37 6.08e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.31 7.23e-03 GO:0031325 positive regulation of cellular metabolic process
1.29 1.07e-02 GO:0009893 positive regulation of metabolic process
1.38 1.20e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36 1.30e-02 GO:0009891 positive regulation of biosynthetic process
1.40 1.74e-02 GO:0010628 positive regulation of gene expression
1.41 2.52e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.32 3.40e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.38 4.03e-02 GO:0030182 neuron differentiation
1.40 4.92e-02 GO:0009887 organ morphogenesis
1.41 4.92e-02 GO:0048666 neuron development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 2.21e-03 GO:0044424 intracellular part
1.22 4.49e-03 GO:0031981 nuclear lumen
1.08 5.14e-03 GO:0005737 cytoplasm
1.05 7.29e-03 GO:0005622 intracellular
1.18 2.49e-02 GO:0044428 nuclear part
1.17 3.25e-02 GO:0031974 membrane-enclosed lumen
1.61 3.53e-02 GO:0045177 apical part of cell
1.06 4.26e-02 GO:0043226 organelle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 3.46e-08 GO:0005515 protein binding
1.06 1.16e-04 GO:0005488 binding
1.41 1.26e-03 GO:0043565 sequence-specific DNA binding