Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.476


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
AHR 196 aryl hydrocarbon receptor
ARNT 405 aryl hydrocarbon receptor nuclear translocator
ARNT2 9915 aryl-hydrocarbon receptor nuclear translocator 2



Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_77391525 2.919


chr3_-_162305319 2.533 NM_033169
NM_001038628
NM_003781
NM_033167
NM_033168
 B3GALNT1




beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)




chr5_+_151131853 2.153 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131709 1.846 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr14_-_23850466 1.813


chr14_-_23850410 1.796 NM_014430
 CIDEB
cell death-inducing DFFA-like effector b
chr14_-_23850481 1.782 CIDEB
cell death-inducing DFFA-like effector b
chr18_-_21184824 1.765


chr19_-_2378581 1.753 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr7_-_131911768 1.714 PLXNA4
plexin A4
chr13_-_39075200 1.700 LHFP
lipoma HMGIC fusion partner
chr11_+_17714070 1.695 NM_001112741
NM_004976
 KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr14_+_23850494 1.663 NM_001143919
 LTB4R
leukotriene B4 receptor
chr5_+_151131655 1.656 NM_005754
NM_198395
 G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr16_+_81218142 1.651 CDH13
cadherin 13, H-cadherin (heart)
chr15_+_81907176 1.628 SH3GL3
SH3-domain GRB2-like 3
chr19_-_2378530 1.621 TIMM13
translocase of inner mitochondrial membrane 13 homolog (yeast)
chr22_-_17891777 1.616 CLDN5
claudin 5
chr2_+_219283751 1.596 NM_014640
 TTLL4
tubulin tyrosine ligase-like family, member 4
chr11_-_78829342 1.585 NM_001098816
 ODZ4
odz, odd Oz/ten-m homolog 4 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 85 entries
enrichment   p-value GO term description
3.36 1.47e-02 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
2.83 5.12e-03 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
2.11 4.71e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.71 3.13e-04 GO:0007268 synaptic transmission
1.70 4.35e-02 GO:0051270 regulation of cellular component movement
1.64 7.51e-03 GO:0009968 negative regulation of signal transduction
1.63 4.61e-03 GO:0023057 negative regulation of signaling
1.62 5.16e-03 GO:0010648 negative regulation of cell communication
1.61 3.16e-02 GO:0006163 purine nucleotide metabolic process
1.58 8.36e-05 GO:0045595 regulation of cell differentiation
1.58 6.93e-03 GO:0019226 transmission of nerve impulse
1.58 6.93e-03 GO:0035637 multicellular organismal signaling
1.55 1.78e-02 GO:0007417 central nervous system development
1.54 4.32e-02 GO:0072358 cardiovascular system development
1.54 4.32e-02 GO:0072359 circulatory system development
1.49 1.50e-04 GO:0050793 regulation of developmental process
1.48 8.59e-03 GO:0019220 regulation of phosphate metabolic process
1.48 8.59e-03 GO:0051174 regulation of phosphorus metabolic process
1.48 1.38e-02 GO:0042325 regulation of phosphorylation
1.45 4.05e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
1.44 4.54e-07 GO:0005654 nucleoplasm
1.40 1.47e-02 GO:0044451 nucleoplasm part
1.36 4.31e-07 GO:0031981 nuclear lumen
1.31 5.86e-07 GO:0031974 membrane-enclosed lumen
1.31 1.18e-06 GO:0070013 intracellular organelle lumen
1.31 2.18e-06 GO:0043233 organelle lumen
1.30 1.59e-05 GO:0044428 nuclear part
1.26 9.92e-04 GO:0005829 cytosol
1.24 4.86e-13 GO:0005634 nucleus
1.15 4.41e-11 GO:0043231 intracellular membrane-bounded organelle
1.15 4.81e-11 GO:0043227 membrane-bounded organelle
1.15 2.38e-10 GO:0005737 cytoplasm
1.14 2.40e-04 GO:0044444 cytoplasmic part
1.14 1.75e-03 GO:0044446 intracellular organelle part
1.13 3.54e-19 GO:0005622 intracellular
1.13 5.84e-17 GO:0044424 intracellular part
1.13 1.52e-11 GO:0043226 organelle
1.13 1.99e-11 GO:0043229 intracellular organelle
1.13 3.30e-03 GO:0044422 organelle part
1.05 5.97e-06 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.51 3.40e-04 GO:0043565 sequence-specific DNA binding
1.48 5.60e-06 GO:0030528 transcription regulator activity
1.42 2.68e-04 GO:0001071 nucleic acid binding transcription factor activity
1.42 2.68e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 1.26e-02 GO:0003723 RNA binding
1.30 5.59e-06 GO:0000166 nucleotide binding
1.22 5.77e-05 GO:0003676 nucleic acid binding
1.17 6.48e-10 GO:0005515 protein binding
1.11 5.78e-14 GO:0005488 binding