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Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.071

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_33493792	3.916		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr16_+_2510323	3.871	NM_001145815 NM_015944	AMDHD2	amidohydrolase domain containing 2
chr6_-_33494042	3.543	NM_001014433 NM_001014837 NM_001014838 NM_001014840 NM_015921	CUTA	cutA divalent cation tolerance homolog (E. coli)
chr6_-_33493898	3.369		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr2_-_97016027	3.217	NM_001122646	FAM178B	family with sequence similarity 178, member B
chr17_-_53764867	2.881
chr6_-_31871394	2.608		VARS	valyl-tRNA synthetase
chr1_-_1700088	2.377	NM_001198993	NADK	NAD kinase
chr19_+_10673105	2.318	NM_031209	QTRT1	queuine tRNA-ribosyltransferase 1
chr22_+_22703107	2.139	NM_001144931	LOC391322	D-dopachrome tautomerase-like
chr9_+_114953087	2.047		SLC31A2	solute carrier family 31 (copper transporters), member 2
chr12_-_56432292	1.923		CDK4	cyclin-dependent kinase 4
chr9_+_114953048	1.872	NM_001860	SLC31A2	solute carrier family 31 (copper transporters), member 2
chr1_-_1699723	1.871	NM_023018	NADK	NAD kinase
chr6_-_31871452	1.788		VARS	valyl-tRNA synthetase
chr8_+_142471290	1.752
chr18_+_9126742	1.747	NM_001083625 NM_015208	ANKRD12	ankyrin repeat domain 12
chr19_+_7493436	1.744	NM_020533	MCOLN1	mucolipin 1
chr12_-_56432377	1.737		CDK4	cyclin-dependent kinase 4
chr2_+_113119985	1.690	NM_005415	SLC20A1	solute carrier family 20 (phosphate transporter), member 1
chr12_-_56432375	1.682		CDK4	cyclin-dependent kinase 4
chr1_-_210939820	1.677		BATF3	basic leucine zipper transcription factor, ATF-like 3
chr1_-_210939929	1.665	NM_018664	BATF3	basic leucine zipper transcription factor, ATF-like 3
chr17_-_44043361	1.647	NM_004502	HOXB7	homeobox B7
chr21_+_37367432	1.638	NM_001001894	TTC3	tetratricopeptide repeat domain 3
chr1_-_21868380	1.610	NM_001145657 NM_002885	RAP1GAP	RAP1 GTPase activating protein
chr11_+_66915997	1.573	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chr6_-_33493640	1.550		CUTA	cutA divalent cation tolerance homolog (E. coli)
chr7_+_150390566	1.525		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr1_-_210939727	1.514
chr10_-_98470164	1.449	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr1_+_20385164	1.438	NM_152376	UBXN10	UBX domain protein 10
chr10_-_45410197	1.432	NM_001002265 NM_145021	MARCH8	membrane-associated ring finger (C3HC4) 8
chr17_-_44043278	1.431		HOXB7	homeobox B7
chr1_+_40399618	1.421	NM_012421	RLF	rearranged L-myc fusion
chr1_+_40399642	1.419		RLF	rearranged L-myc fusion
chr8_-_70908130	1.415	NM_001146008	SLCO5A1	solute carrier organic anion transporter family, member 5A1
chr7_+_129913271	1.414	NM_177524	MEST	mesoderm specific transcript homolog (mouse)
chr12_-_56432385	1.405	NM_000075	CDK4	cyclin-dependent kinase 4
chr3_+_23961739	1.395	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr19_+_54149963	1.385		BAX	BCL2-associated X protein
chr19_+_6415259	1.368	NM_139161 NM_174881	CRB3	crumbs homolog 3 (Drosophila)
chr19_+_2928480	1.350	NM_001143986 NM_024760	TLE6	transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)
chr1_+_11718715	1.341	NM_001040194 NM_001040195 NM_001040196 NM_001040197 NM_020350	AGTRAP	angiotensin II receptor-associated protein
chr1_-_201162938	1.324		KLHL12	kelch-like 12 (Drosophila)
chr22_-_19180075	1.311	NM_032775	KLHL22	kelch-like 22 (Drosophila)
chr1_-_201162991	1.291	NM_021633	KLHL12	kelch-like 12 (Drosophila)
chr18_-_43711452	1.283	NM_001003652 NM_001135937	SMAD2	SMAD family member 2
chr4_-_103485600	1.281	NM_001135146	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr20_+_43953606	1.277		CTSA	cathepsin A
chr1_+_11718764	1.241		AGTRAP	angiotensin II receptor-associated protein
chr17_+_52518098	1.229		AKAP1	A kinase (PRKA) anchor protein 1
chr19_+_10626106	1.211		ILF3	interleukin enhancer binding factor 3, 90kDa
chr6_-_31871530	1.201	NM_006295	VARS	valyl-tRNA synthetase
chr22_+_38903825	1.198	NM_001162501 NM_015088	TNRC6B	trinucleotide repeat containing 6B
chr10_+_51497716	1.192		FAM21A	family with sequence similarity 21, member A
chr1_+_205293217	1.191	NM_001018053 NM_006212	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr11_+_75157414	1.172	NM_032564	DGAT2	diacylglycerol O-acyltransferase 2
chr22_-_19543099	1.170		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr18_-_45241014	1.159	NM_017653	DYM	dymeclin
chr12_+_119562737	1.159	NM_001033677	CABP1	calcium binding protein 1
chrX_-_49347279	1.150	NM_003785	PAGE1	P antigen family, member 1 (prostate associated)
chr9_-_137731139	1.142	NM_001012415 NM_001101677	SOHLH1	spermatogenesis and oogenesis specific basic helix-loop-helix 1
chr1_+_17954394	1.136	NM_030812	ACTL8	actin-like 8
chr12_-_46439127	1.135	NM_001098531	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_31964909	1.113
chr21_-_37367259	1.107	NM_153682	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr17_+_46599081	1.103	NM_001018138	NME2	non-metastatic cells 2, protein (NM23B) expressed in
chr4_+_970775	1.100	NM_000203	IDUA	iduronidase, alpha-L-
chr16_+_2807164	1.096	NM_006799 NM_144956 NM_144957	PRSS21	protease, serine, 21 (testisin)
chr1_+_44213260	1.081		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr6_-_43305156	1.077	NM_006443 NM_199184	C6orf108	chromosome 6 open reading frame 108
chr12_+_110935618	1.074		ERP29	endoplasmic reticulum protein 29
chr3_+_160002605	1.073		MFSD1	major facilitator superfamily domain containing 1
chr7_+_107997527	1.065		DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr12_-_112107587	1.064	NM_001111322 NM_024072	DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
chr1_-_77920914	1.060	NM_015534	ZZZ3	zinc finger, ZZ-type containing 3
chr3_-_4483955	1.055	NM_001164674 NM_001164675 NM_182760	SUMF1	sulfatase modifying factor 1
chr7_-_23476497	1.052	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr16_-_87450734	1.041		GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr19_+_54149941	1.023		BAX	BCL2-associated X protein
chr16_+_2807228	1.019		PRSS21	protease, serine, 21 (testisin)
chr1_+_111544469	1.013
chr17_-_37586716	1.006	NM_012285	KCNH4	potassium voltage-gated channel, subfamily H (eag-related), member 4
chr22_-_19543012	1.004		PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha
chr16_+_29373365	1.001	NM_001014999 NM_001015000 NM_024044 NM_178044	SLX1A-SULT1A3 SLX1A SLX1B	SLX1A-SULT1A3 read-through transcript SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
chr3_-_4483952	0.999		SUMF1	sulfatase modifying factor 1
chr1_-_11788550	0.996		MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
chr1_+_11718798	0.991		AGTRAP	angiotensin II receptor-associated protein
chr1_-_165211128	0.990	NM_199351	ILDR2	immunoglobulin-like domain containing receptor 2
chr17_-_35273947	0.986	NM_012481 NM_183228 NM_183229 NM_183230 NM_183231 NM_183232	IKZF3	IKAROS family zinc finger 3 (Aiolos)
chrX_+_49480643	0.983	NM_007003	PAGE4	P antigen family, member 4 (prostate associated)
chr1_+_44213229	0.983		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr10_+_51497660	0.983	NM_001005751	FAM21C FAM21A	family with sequence similarity 21, member C family with sequence similarity 21, member A
chr18_+_19337437	0.975	NM_013326	C18orf8	chromosome 18 open reading frame 8
chr19_+_14405100	0.965	NM_002741	PKN1	protein kinase N1
chr11_+_75157450	0.961		DGAT2	diacylglycerol O-acyltransferase 2
chr16_-_2037819	0.953	NM_002528	NTHL1	nth endonuclease III-like 1 (E. coli)
chr3_+_160002582	0.952		MFSD1	major facilitator superfamily domain containing 1
chr1_+_234916376	0.949	NM_001103	ACTN2	actinin, alpha 2
chr1_-_26105954	0.944	NM_203399	STMN1	stathmin 1
chr9_+_130124566	0.942	NM_016035	COQ4	coenzyme Q4 homolog (S. cerevisiae)
chr3_+_160002408	0.937	NM_001167903 NM_022736	MFSD1	major facilitator superfamily domain containing 1
chr1_+_44213182	0.937	NM_001039457 NM_004047	ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr4_+_609362	0.934	NM_000283 NM_001145291	PDE6B	phosphodiesterase 6B, cGMP-specific, rod, beta
chr16_+_83618804	0.933	NM_014732	KIAA0513	KIAA0513
chr22_-_17798998	0.933		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_44213200	0.926		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr19_+_10392128	0.925	NM_001111307	PDE4A	phosphodiesterase 4A, cAMP-specific
chr17_+_37972590	0.922	NM_170607 NM_198204 NM_198205	MLX	MAX-like protein X
chr11_-_47620590	0.912	NM_014342	MTCH2	mitochondrial carrier homolog 2 (C. elegans)
chr11_+_18300689	0.903		GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa
chr17_-_41018291	0.898
chr22_-_17799177	0.892		HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr1_+_11788889	0.878		CLCN6	chloride channel 6
chr22_-_17799215	0.878	NM_003325	HIRA	HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr11_+_62295412	0.873	NM_006473	TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr1_+_44213210	0.854		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr3_-_4483928	0.847		SUMF1	sulfatase modifying factor 1
chr20_+_46971618	0.846	NM_006420	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr6_+_160310118	0.841	NM_000876	IGF2R	insulin-like growth factor 2 receptor
chr21_-_37366684	0.836	NM_153681	PIGP	phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_7052985	0.835	NM_001003698 NM_001003699 NM_001003700	RREB1	ras responsive element binding protein 1
chr3_+_4996096	0.832	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr4_-_101090431	0.830		H2AFZ	H2A histone family, member Z
chr19_-_14748623	0.828		EMR2	egf-like module containing, mucin-like, hormone receptor-like 2
chr6_-_44333002	0.827	NM_178148	SLC35B2	solute carrier family 35, member B2
chr3_-_20202622	0.826	NM_001012409 NM_001012410 NM_001012411 NM_001012412 NM_001012413 NM_138484	SGOL1	shugoshin-like 1 (S. pombe)
chr11_+_120399966	0.821	NM_001130047 NM_152715	TBCEL	tubulin folding cofactor E-like
chr6_+_36670117	0.819		SRSF3	serine/arginine-rich splicing factor 3
chr10_+_45542653	0.817	NM_001169106 NM_001169107 NM_015262	FAM21C FAM21A	family with sequence similarity 21, member C family with sequence similarity 21, member A
chr19_-_46883935	0.814	NM_006890	CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7
chr15_+_86983038	0.814	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr17_-_34157962	0.812	NM_007144	PCGF2	polycomb group ring finger 2
chr16_+_65840275	0.807	NM_004594	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr13_-_35686665	0.803	NM_017826	SOHLH2	spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr1_+_32251988	0.802	NM_006559	KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1
chr1_+_1157485	0.802	NM_080605	B3GALT6	UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr1_+_26368969	0.801	NM_015871	ZNF593	zinc finger protein 593
chr3_+_160002571	0.800		MFSD1	major facilitator superfamily domain containing 1
chr3_+_160002619	0.789		MFSD1	major facilitator superfamily domain containing 1
chr12_+_110935644	0.785		ERP29	endoplasmic reticulum protein 29
chr16_+_24458349	0.784	NM_006910 NM_018703 NM_032626	RBBP6	retinoblastoma binding protein 6
chr12_+_51932136	0.782	NM_032889	MFSD5	major facilitator superfamily domain containing 5
chr16_-_1465007	0.782		CLCN7	chloride channel 7
chr10_-_43223226	0.777	NM_001098206	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr16_+_2037986	0.777	NM_000548 NM_001077183 NM_001114382	TSC2	tuberous sclerosis 2
chr4_+_186176988	0.776	NM_001029887	HELT	HES/HEY-like transcription factor
chr2_+_26840626	0.774	NM_017877	CENPA C2orf18	centromere protein A chromosome 2 open reading frame 18
chr7_+_106472243	0.774	NM_002736	PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta
chr11_-_71492019	0.773	NM_017907	LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr4_-_103485419	0.772	NM_001135147	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr6_+_36670067	0.768	NM_003017	SRSF3	serine/arginine-rich splicing factor 3
chr12_-_54995923	0.767		CNPY2	canopy 2 homolog (zebrafish)
chr7_+_107997544	0.766	NM_012328	DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9
chr5_-_176869943	0.764	NM_001144875 NM_001144876	DOK3	docking protein 3
chr6_+_36670113	0.760		SRSF3	serine/arginine-rich splicing factor 3
chr12_-_121316907	0.759		VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr1_+_10015577	0.759	NM_001105562 NM_006048	UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)
chr17_-_31964723	0.756		MYO19	myosin XIX
chr12_+_70519753	0.756	NM_001146213 NM_001146214 NM_022771	TBC1D15	TBC1 domain family, member 15
chr10_+_70150936	0.755	NM_018237	CCAR1	cell division cycle and apoptosis regulator 1
chr1_+_32992131	0.753
chr7_+_882704	0.753	NM_015949	GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr5_+_154115046	0.750		LARP1	La ribonucleoprotein domain family, member 1
chr7_-_100331417	0.747	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr19_+_1226510	0.743	NM_017914	C19orf24	chromosome 19 open reading frame 24
chr3_-_110319598	0.739	NM_014429	MORC1	MORC family CW-type zinc finger 1
chr12_-_54996044	0.737		CNPY2	canopy 2 homolog (zebrafish)
chr3_+_4996141	0.737		BHLHE40	basic helix-loop-helix family, member e40
chr12_+_51932173	0.737		MFSD5	major facilitator superfamily domain containing 5
chr18_-_19271814	0.736	NM_032933	C18orf45	chromosome 18 open reading frame 45
chr1_-_227828339	0.735		TAF5L	TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr7_+_101861007	0.734		ORAI2	ORAI calcium release-activated calcium modulator 2
chr11_+_63463009	0.730	NM_024771	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr8_-_103494073	0.730		UBR5	ubiquitin protein ligase E3 component n-recognin 5
chr1_+_55044323	0.729	NM_001110533 NM_152607	C1orf177	chromosome 1 open reading frame 177
chr8_-_133140808	0.721	NM_001080399	OC90	otoconin 90
chr12_+_112107747	0.718	NM_032848	C12orf52	chromosome 12 open reading frame 52
chr1_+_10015736	0.717		UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)
chr8_-_42028634	0.715	NM_001099412 NM_001099413 NM_006766	MYST3	MYST histone acetyltransferase (monocytic leukemia) 3
chr21_-_42247007	0.714	NM_015500	C2CD2	C2 calcium-dependent domain containing 2
chr12_-_121316997	0.714	NM_022916	VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr12_+_49918921	0.712		DAZAP2	DAZ associated protein 2
chrX_-_19815526	0.711		SH3KBP1	SH3-domain kinase binding protein 1
chr16_-_47872973	0.709		CBLN1	cerebellin 1 precursor
chrX_-_47394937	0.709	NM_001114123 NM_005229	ELK1	ELK1, member of ETS oncogene family
chr9_+_130749791	0.706	NM_015354	NUP188	nucleoporin 188kDa
chr3_-_4483939	0.705		SUMF1	sulfatase modifying factor 1
chrX_+_130984912	0.705	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr1_-_11788666	0.705	NM_005957	MTHFR	methylenetetrahydrofolate reductase (NAD(P)H)
chr1_-_27099515	0.704		GPATCH3	G patch domain containing 3
chr11_-_59334706	0.693	NM_017840	MRPL16	mitochondrial ribosomal protein L16
chr2_+_176724583	0.691
chr2_-_175741096	0.689	NM_001880	ATF2	activating transcription factor 2
chr1_+_11788827	0.684		CLCN6	chloride channel 6
chr11_-_3620060	0.684	NM_053017 NM_001079536	ART5	ADP-ribosyltransferase 5
chr7_-_107997132	0.684	NM_182529 NM_001130475	THAP5	THAP domain containing 5
chr9_-_139316523	0.683	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr12_+_51932252	0.681		MFSD5	major facilitator superfamily domain containing 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	1.90e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21	2.32e-06	GO:0044237	cellular metabolic process
1.18	3.32e-06	GO:0008152	metabolic process
1.33	4.06e-06	GO:0034641	cellular nitrogen compound metabolic process
1.32	9.75e-06	GO:0006807	nitrogen compound metabolic process
1.20	1.46e-05	GO:0044238	primary metabolic process
1.25	2.60e-05	GO:0044260	cellular macromolecule metabolic process
1.38	5.93e-05	GO:0090304	nucleic acid metabolic process
1.41	3.65e-04	GO:0016070	RNA metabolic process
1.39	6.14e-04	GO:0010467	gene expression
1.09	7.11e-04	GO:0009987	cellular process
1.20	1.63e-03	GO:0043170	macromolecule metabolic process
1.28	2.10e-02	GO:0009058	biosynthetic process
1.28	2.14e-02	GO:0044249	cellular biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.41e-19	GO:0044424	intracellular part
1.16	1.81e-18	GO:0005622	intracellular
1.22	6.35e-15	GO:0005737	cytoplasm
1.20	2.00e-14	GO:0043227	membrane-bounded organelle
1.20	3.39e-14	GO:0043231	intracellular membrane-bounded organelle
1.18	9.90e-14	GO:0043226	organelle
1.18	2.00e-13	GO:0043229	intracellular organelle
1.24	7.90e-10	GO:0044444	cytoplasmic part
1.24	2.57e-08	GO:0005634	nucleus
2.28	7.33e-08	GO:0005773	vacuole
1.22	4.46e-07	GO:0044446	intracellular organelle part
2.32	7.27e-07	GO:0000323	lytic vacuole
2.32	7.27e-07	GO:0005764	lysosome
1.22	9.70e-07	GO:0044422	organelle part
1.36	1.73e-05	GO:0070013	intracellular organelle lumen
1.35	2.71e-05	GO:0031974	membrane-enclosed lumen
1.34	6.88e-05	GO:0043233	organelle lumen
1.35	8.81e-05	GO:0044428	nuclear part
1.37	2.28e-04	GO:0031981	nuclear lumen
1.44	2.75e-04	GO:0005654	nucleoplasm
6.03	4.06e-04	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.68	1.81e-03	GO:0030529	ribonucleoprotein complex
1.31	3.11e-03	GO:0005829	cytosol
1.51	1.26e-02	GO:0044451	nucleoplasm part
1.87	4.87e-02	GO:0016604	nuclear body

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.20	1.52e-08	GO:0005515	protein binding
1.65	1.71e-05	GO:0003723	RNA binding
1.09	4.72e-05	GO:0005488	binding
1.77	8.18e-04	GO:0016874	ligase activity
1.90	3.95e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
4.26	1.38e-02	GO:0003727	single-stranded RNA binding
1.16	1.61e-02	GO:0003824	catalytic activity
1.21	2.68e-02	GO:0003676	nucleic acid binding