Motif ID: ATF4.p2

Z-value: 1.283


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)



Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_139497933 2.959 NM_016217
 HECA
headcase homolog (Drosophila)
chrX_-_151996613 1.691 NM_032882
 PNMA6A
paraneoplastic antigen like 6A
chrX_+_151991474 1.588 NM_001170944
NM_032882
 LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr5_+_112877251 1.517 NM_022828
 YTHDC2
YTH domain containing 2
chr7_-_129379947 1.427 NM_003344
NM_182697
 UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr21_+_44033871 1.424 RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr8_-_145097031 1.405 NM_201380
 PLEC
plectin
chr4_-_120595218 1.379


chr9_-_98421894 1.362 NM_003671
NM_033331
 CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr1_+_26368969 1.353 NM_015871
 ZNF593
zinc finger protein 593
chr21_+_44033821 1.284 NM_003683
 RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr10_+_134060681 1.217 NM_001098637
NM_138499
 PWWP2B

PWWP domain containing 2B

chr11_+_67107852 1.067 GSTP1
glutathione S-transferase pi 1
chr12_+_52665196 1.043 NM_017409
 HOXC10
homeobox C10
chr1_+_226712430 1.035 NM_175055
 HIST3H2BB
histone cluster 3, H2bb
chr21_-_43671355 0.950 NM_173354
 SIK1
salt-inducible kinase 1
chr1_-_226712140 0.950 NM_033445
 HIST3H2A
histone cluster 3, H2a
chr7_-_44992729 0.938 C7orf40
chromosome 7 open reading frame 40
chr22_-_17546296 0.933 NM_005984
 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chrX_-_47364173 0.928 NM_006950
NM_133499
 SYN1

synapsin I


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
2.16 1.02e-02 GO:0019941 modification-dependent protein catabolic process
2.15 1.19e-02 GO:0043632 modification-dependent macromolecule catabolic process
2.15 1.54e-02 GO:0006511 ubiquitin-dependent protein catabolic process
2.11 1.92e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
2.07 3.02e-02 GO:0044257 cellular protein catabolic process
1.88 3.63e-02 GO:0006325 chromatin organization
1.86 3.35e-03 GO:0051276 chromosome organization
1.83 3.52e-02 GO:0044265 cellular macromolecule catabolic process
1.82 1.28e-02 GO:0006259 DNA metabolic process
1.75 1.37e-02 GO:0022403 cell cycle phase
1.72 5.95e-03 GO:0022402 cell cycle process
1.68 1.31e-02 GO:0033554 cellular response to stress
1.64 3.21e-03 GO:0007049 cell cycle
1.63 3.79e-09 GO:0090304 nucleic acid metabolic process
1.62 1.64e-03 GO:0044248 cellular catabolic process
1.58 2.11e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 3.71e-04 GO:0006996 organelle organization
1.53 7.81e-05 GO:0010467 gene expression
1.51 9.23e-10 GO:0034641 cellular nitrogen compound metabolic process
1.51 7.94e-04 GO:0016070 RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
6.45 1.87e-02 GO:0000159 protein phosphatase type 2A complex
4.04 4.57e-02 GO:0008287 protein serine/threonine phosphatase complex
2.55 1.71e-02 GO:0000775 chromosome, centromeric region
2.28 4.40e-07 GO:0044427 chromosomal part
2.14 2.64e-02 GO:0000785 chromatin
2.07 4.91e-06 GO:0005694 chromosome
1.74 1.09e-07 GO:0005654 nucleoplasm
1.69 6.52e-10 GO:0031981 nuclear lumen
1.64 5.22e-11 GO:0070013 intracellular organelle lumen
1.64 1.21e-10 GO:0044428 nuclear part
1.60 3.74e-10 GO:0043233 organelle lumen
1.58 1.80e-09 GO:0031974 membrane-enclosed lumen
1.38 8.33e-05 GO:0043228 non-membrane-bounded organelle
1.38 8.33e-05 GO:0043232 intracellular non-membrane-bounded organelle
1.37 6.89e-13 GO:0005634 nucleus
1.36 2.39e-12 GO:0044446 intracellular organelle part
1.35 1.76e-11 GO:0044422 organelle part
1.27 1.43e-16 GO:0043231 intracellular membrane-bounded organelle
1.27 1.95e-16 GO:0043227 membrane-bounded organelle
1.25 1.85e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.59 4.94e-02 GO:0019899 enzyme binding
1.51 4.56e-02 GO:0001071 nucleic acid binding transcription factor activity
1.51 4.56e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.36 3.94e-03 GO:0003677 DNA binding
1.31 1.04e-03 GO:0003676 nucleic acid binding
1.28 2.58e-11 GO:0005515 protein binding
1.13 2.01e-08 GO:0005488 binding