Motif ID: ATF5_CREB3.p2

Z-value: 1.783


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3



Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_32610161 3.114 NM_032514
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr3_-_102878301 2.846 NM_014415
 ZBTB11
zinc finger and BTB domain containing 11
chr4_-_187884721 2.010


chr3_+_141136691 1.522 NM_022131
 CLSTN2
calsyntenin 2
chr2_+_10969513 1.436 NM_002236
 KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr22_-_42589543 1.422 NM_014351
 SULT4A1
sulfotransferase family 4A, member 1
chr3_+_102775677 1.361 PCNP
PEST proteolytic signal containing nuclear protein
chr2_+_108702338 1.302 NM_006267
 RANBP2
RAN binding protein 2
chr3_+_101462375 1.284 NM_018309
 TBC1D23
TBC1 domain family, member 23
chr4_+_145786622 1.172 NM_022475
 HHIP
hedgehog interacting protein
chr14_+_67156323 1.100 NM_001172
 ARG2
arginase, type II
chr17_+_37098668 1.050 EIF1
eukaryotic translation initiation factor 1
chr3_+_141136896 1.001 CLSTN2
calsyntenin 2
chr2_-_216009015 0.993 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
 FN1





fibronectin 1





chr1_-_212791597 0.969 NM_005401
 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr20_-_4177519 0.968 NM_000678
 ADRA1D
adrenergic, alpha-1D-, receptor
chr17_+_632356 0.948 RNMTL1
RNA methyltransferase like 1
chr4_-_1980756 0.939 NM_005663
 WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr3_-_64186151 0.939 NM_198859
 PRICKLE2
prickle homolog 2 (Drosophila)
chr1_-_212791467 0.937 PTPN14
protein tyrosine phosphatase, non-receptor type 14

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 63 entries
enrichment   p-value GO term description
2.97 1.81e-03 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
2.88 9.44e-03 GO:0034130 toll-like receptor 1 signaling pathway
2.88 9.44e-03 GO:0034134 toll-like receptor 2 signaling pathway
2.55 3.63e-02 GO:0002224 toll-like receptor signaling pathway
1.67 6.03e-06 GO:0046907 intracellular transport
1.58 8.94e-07 GO:0051649 establishment of localization in cell
1.58 1.06e-04 GO:0006351 transcription, DNA-dependent
1.57 1.02e-02 GO:0006396 RNA processing
1.56 2.26e-07 GO:0051641 cellular localization
1.54 8.32e-04 GO:0045184 establishment of protein localization
1.54 1.24e-02 GO:0030182 neuron differentiation
1.52 3.06e-10 GO:0010467 gene expression
1.52 5.18e-09 GO:0009059 macromolecule biosynthetic process
1.52 7.08e-09 GO:0034645 cellular macromolecule biosynthetic process
1.52 2.51e-03 GO:0015031 protein transport
1.51 8.29e-04 GO:0032774 RNA biosynthetic process
1.50 1.40e-08 GO:0016070 RNA metabolic process
1.50 1.17e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.44 7.32e-05 GO:0007399 nervous system development
1.44 7.16e-03 GO:0008104 protein localization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
2.90 1.78e-02 GO:0005793 ER-Golgi intermediate compartment
1.51 4.22e-03 GO:0015630 microtubule cytoskeleton
1.46 1.84e-02 GO:0044451 nucleoplasm part
1.42 7.91e-09 GO:0044428 nuclear part
1.42 3.10e-07 GO:0031981 nuclear lumen
1.42 1.62e-04 GO:0005654 nucleoplasm
1.36 9.37e-07 GO:0070013 intracellular organelle lumen
1.36 4.49e-02 GO:0005794 Golgi apparatus
1.35 1.62e-06 GO:0043233 organelle lumen
1.35 1.93e-06 GO:0031974 membrane-enclosed lumen
1.35 4.20e-02 GO:0005783 endoplasmic reticulum
1.29 1.14e-05 GO:0043234 protein complex
1.29 1.93e-03 GO:0005829 cytosol
1.28 4.25e-02 GO:0012505 endomembrane system
1.27 1.52e-12 GO:0005634 nucleus
1.27 1.67e-06 GO:0032991 macromolecular complex
1.26 2.00e-12 GO:0044422 organelle part
1.26 7.05e-12 GO:0044446 intracellular organelle part
1.21 2.87e-18 GO:0043227 membrane-bounded organelle
1.21 7.26e-18 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.63 2.21e-06 GO:0003723 RNA binding
1.59 8.73e-07 GO:0001071 nucleic acid binding transcription factor activity
1.59 8.73e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 2.82e-04 GO:0043565 sequence-specific DNA binding
1.45 1.02e-03 GO:0030528 transcription regulator activity
1.33 1.82e-05 GO:0000166 nucleotide binding
1.33 8.14e-03 GO:0005524 ATP binding
1.32 1.23e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.32 7.53e-03 GO:0030554 adenyl nucleotide binding
1.32 1.08e-02 GO:0032559 adenyl ribonucleotide binding
1.31 1.19e-03 GO:0017076 purine nucleotide binding
1.31 1.55e-03 GO:0032553 ribonucleotide binding
1.31 1.55e-03 GO:0032555 purine ribonucleotide binding
1.27 1.76e-05 GO:0003676 nucleic acid binding
1.20 5.89e-11 GO:0005515 protein binding
1.10 1.73e-08 GO:0005488 binding