Motif ID: ATF6.p2

Z-value: 1.436


Transcription factors associated with ATF6.p2:

Gene SymbolEntrez IDGene Name
ATF6 22926 activating transcription factor 6



Activity profile for motif ATF6.p2.

activity profile for motif ATF6.p2


Sorted Z-values histogram for motif ATF6.p2

Sorted Z-values for motif ATF6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_73756668 1.212 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr1_-_202595666 1.093 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr5_-_94916416 0.896 NM_014639
TTC37
tetratricopeptide repeat domain 37
chr5_+_94916533 0.853 NM_198150
ARSK
arylsulfatase family, member K
chr10_-_118022965 0.838 NM_005264
GFRA1
GDNF family receptor alpha 1
chr19_-_52709975 0.836 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr19_-_52710089 0.809 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr7_+_27191534 0.777 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr2_-_192767494 0.769 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chrX_-_55532355 0.764 NM_201286
USP51
ubiquitin specific peptidase 51
chr1_+_29435534 0.740 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr2_-_133144094 0.716 LYPD1
LY6/PLAUR domain containing 1
chr19_-_52710129 0.713 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr18_+_7557313 0.695 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr11_+_113435506 0.688 ZBTB16
zinc finger and BTB domain containing 16
chr4_+_166519392 0.683 NM_001873
CPE
carboxypeptidase E
chr8_+_106400322 0.683 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr4_+_75529716 0.676 NM_001657
AREG
amphiregulin
chr7_-_19123765 0.676 TWIST1
twist homolog 1 (Drosophila)
chr21_-_43671355 0.673 NM_173354
SIK1
salt-inducible kinase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 68 entries
enrichment   p-value GO term description
9.97 1.60e-02 GO:0048194 Golgi vesicle budding
9.97 1.60e-02 GO:0048200 Golgi transport vesicle coating
9.97 1.60e-02 GO:0048205 COPI coating of Golgi vesicle
9.72 6.67e-08 GO:0048199 vesicle targeting, to, from or within Golgi
7.47 2.55e-05 GO:0006901 vesicle coating
7.18 4.61e-05 GO:0006900 membrane budding
6.98 4.68e-06 GO:0006903 vesicle targeting
5.34 1.04e-04 GO:0051650 establishment of vesicle localization
4.23 3.26e-03 GO:0051648 vesicle localization
2.95 1.51e-03 GO:0048193 Golgi vesicle transport
2.25 4.40e-03 GO:0035295 tube development
2.16 2.76e-02 GO:0001568 blood vessel development
2.03 4.36e-02 GO:0001501 skeletal system development
1.97 2.70e-02 GO:0043009 chordate embryonic development
1.97 2.70e-02 GO:0048598 embryonic morphogenesis
1.95 3.65e-02 GO:0009792 embryo development ending in birth or egg hatching
1.92 1.96e-03 GO:0070727 cellular macromolecule localization
1.90 3.39e-03 GO:0034613 cellular protein localization
1.82 4.64e-03 GO:0009887 organ morphogenesis
1.76 3.63e-03 GO:0009790 embryo development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
5.81 3.98e-02 GO:0030530 heterogeneous nuclear ribonucleoprotein complex
3.28 2.61e-03 GO:0000790 nuclear chromatin
3.17 4.04e-02 GO:0030117 membrane coat
3.17 4.04e-02 GO:0048475 coated membrane
2.37 1.01e-02 GO:0044454 nuclear chromosome part
2.14 2.89e-02 GO:0000228 nuclear chromosome
2.13 2.74e-06 GO:0000139 Golgi membrane
2.05 3.64e-02 GO:0000785 chromatin
2.01 2.19e-06 GO:0044431 Golgi apparatus part
1.72 8.25e-06 GO:0005794 Golgi apparatus
1.72 4.65e-02 GO:0044427 chromosomal part
1.53 3.68e-03 GO:0005783 endoplasmic reticulum
1.52 4.40e-06 GO:0031981 nuclear lumen
1.52 7.13e-04 GO:0005654 nucleoplasm
1.50 1.41e-04 GO:0012505 endomembrane system
1.45 7.61e-06 GO:0043233 organelle lumen
1.44 1.09e-05 GO:0031974 membrane-enclosed lumen
1.44 1.70e-05 GO:0070013 intracellular organelle lumen
1.44 2.75e-05 GO:0044428 nuclear part
1.35 6.08e-03 GO:0031090 organelle membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.02 1.46e-02 GO:0008134 transcription factor binding
1.92 5.19e-06 GO:0043565 sequence-specific DNA binding
1.76 1.90e-06 GO:0030528 transcription regulator activity
1.74 4.91e-06 GO:0001071 nucleic acid binding transcription factor activity
1.74 4.91e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 5.38e-03 GO:0003677 DNA binding
1.29 1.94e-03 GO:0003676 nucleic acid binding
1.26 3.35e-10 GO:0005515 protein binding
1.11 3.47e-05 GO:0005488 binding