Motif ID: EP300.p2

Z-value: 1.156


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300



Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_126839546 2.429 NM_001083914
 CTBP2
C-terminal binding protein 2
chr2_+_130846263 1.642 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr21_+_44941514 1.448 NM_198699
 KRTAP10-12
keratin associated protein 10-12
chr22_+_35586950 1.423 NM_000631
NM_013416
 NCF4

neutrophil cytosolic factor 4, 40kDa

chr4_-_122213018 1.367 NM_024574
 C4orf31
chromosome 4 open reading frame 31
chr2_+_182029863 1.333 NM_000885
 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr11_+_131286513 1.214 NTM
neurotrimin
chr11_+_1925162 1.193 MRPL23
mitochondrial ribosomal protein L23
chr11_-_64368616 1.164 NM_017525
 CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr22_+_40800193 1.163 NM_001002034
 FAM109B
family with sequence similarity 109, member B
chr3_+_113061296 1.159 PHLDB2
pleckstrin homology-like domain, family B, member 2
chr5_+_174084137 1.120 NM_002449
 MSX2
msh homeobox 2
chr11_+_1925075 1.118 NM_021134
 MRPL23
mitochondrial ribosomal protein L23
chr12_+_51727076 1.054 NM_198316
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_23990228 1.044 NM_007260
 LYPLA2
lysophospholipase II
chr3_+_113061330 1.040 PHLDB2
pleckstrin homology-like domain, family B, member 2
chr2_+_182030173 1.010 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr9_-_33437527 1.007 NM_004925
 AQP3
aquaporin 3 (Gill blood group)
chr11_+_124539814 1.003 PKNOX2
PBX/knotted 1 homeobox 2
chr1_-_29322993 1.001 NM_001003682
 TMEM200B
transmembrane protein 200B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
1.53 7.86e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.42 8.90e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.32 3.86e-02 GO:0032774 RNA biosynthetic process
1.26 4.49e-02 GO:0009966 regulation of signal transduction
1.25 7.99e-03 GO:0016070 RNA metabolic process
1.25 1.50e-02 GO:0023051 regulation of signaling
1.23 3.88e-04 GO:0048522 positive regulation of cellular process
1.22 2.33e-02 GO:0030154 cell differentiation
1.21 8.69e-04 GO:0048518 positive regulation of biological process
1.21 4.45e-02 GO:0048869 cellular developmental process
1.19 2.14e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 4.84e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.17 4.59e-03 GO:0080090 regulation of primary metabolic process
1.17 6.25e-03 GO:0071840 cellular component organization or biogenesis
1.17 9.16e-03 GO:0016043 cellular component organization
1.16 1.74e-02 GO:0060255 regulation of macromolecule metabolic process
1.16 2.13e-02 GO:0031323 regulation of cellular metabolic process
1.15 4.21e-03 GO:0044260 cellular macromolecule metabolic process
1.15 2.41e-02 GO:0019222 regulation of metabolic process
1.12 3.49e-05 GO:0050794 regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.84 4.45e-04 GO:0031252 cell leading edge
1.55 1.16e-02 GO:0015629 actin cytoskeleton
1.37 2.18e-02 GO:0030054 cell junction
1.23 1.24e-02 GO:0005856 cytoskeleton
1.13 1.74e-04 GO:0005634 nucleus
1.11 2.01e-06 GO:0005737 cytoplasm
1.09 1.69e-05 GO:0043226 organelle
1.08 6.68e-07 GO:0044424 intracellular part
1.08 2.71e-05 GO:0043229 intracellular organelle
1.07 9.95e-07 GO:0005622 intracellular
1.07 1.82e-02 GO:0043227 membrane-bounded organelle
1.07 2.28e-02 GO:0043231 intracellular membrane-bounded organelle
1.03 1.84e-02 GO:0044464 cell part
1.03 1.92e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.53 1.78e-02 GO:0003779 actin binding
1.45 1.93e-03 GO:0008092 cytoskeletal protein binding
1.30 9.90e-03 GO:0030528 transcription regulator activity
1.17 3.69e-13 GO:0005515 protein binding
1.07 1.26e-06 GO:0005488 binding