• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: EP300.p2

Z-value: 1.156

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_-_126839546	2.429	NM_001083914	CTBP2	C-terminal binding protein 2
chr2_+_130846263	1.642		PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr21_+_44941514	1.448	NM_198699	KRTAP10-12	keratin associated protein 10-12
chr22_+_35586950	1.423	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr4_-_122213018	1.367	NM_024574	C4orf31	chromosome 4 open reading frame 31
chr2_+_182029863	1.333	NM_000885	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr11_+_131286513	1.214		NTM	neurotrimin
chr11_+_1925162	1.193		MRPL23	mitochondrial ribosomal protein L23
chr11_-_64368616	1.164	NM_017525	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)
chr22_+_40800193	1.163	NM_001002034	FAM109B	family with sequence similarity 109, member B
chr3_+_113061296	1.159		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr5_+_174084137	1.120	NM_002449	MSX2	msh homeobox 2
chr11_+_1925075	1.118	NM_021134	MRPL23	mitochondrial ribosomal protein L23
chr12_+_51727076	1.054	NM_198316	TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr1_+_23990228	1.044	NM_007260	LYPLA2	lysophospholipase II
chr3_+_113061330	1.040		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr2_+_182030173	1.010		ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr9_-_33437527	1.007	NM_004925	AQP3	aquaporin 3 (Gill blood group)
chr11_+_124539814	1.003		PKNOX2	PBX/knotted 1 homeobox 2
chr1_-_29322993	1.001	NM_001003682	TMEM200B	transmembrane protein 200B
chr6_+_73388713	1.000		KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr22_+_40800213	0.985		FAM109B	family with sequence similarity 109, member B
chr3_+_113061218	0.983	NM_001134439	PHLDB2	pleckstrin homology-like domain, family B, member 2
chr22_-_30356783	0.973	NM_014338	PISD	phosphatidylserine decarboxylase
chr11_+_124539768	0.944	NM_022062	PKNOX2	PBX/knotted 1 homeobox 2
chr13_-_39075304	0.919		LHFP	lipoma HMGIC fusion partner
chr3_+_160964574	0.888		SCHIP1	schwannomin interacting protein 1
chr12_-_118725672	0.879		CIT	citron (rho-interacting, serine/threonine kinase 21)
chr1_+_156229934	0.866		KIRREL	kin of IRRE like (Drosophila)
chr11_-_72111027	0.864	NM_001135190 NM_015242	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr9_-_131444098	0.863	NM_017873 NM_177999	ASB6	ankyrin repeat and SOCS box containing 6
chr9_-_116920232	0.856	NM_002160	TNC	tenascin C
chr18_+_5228065	0.854		LOC339290	hypothetical LOC339290
chr14_+_105028614	0.832	NM_001134875 NM_001134876	C14orf80	chromosome 14 open reading frame 80
chr15_+_66658626	0.808	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr6_+_149680747	0.798		TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr12_-_49853155	0.781	NM_001173452 NM_001173453 NM_005653	TFCP2	transcription factor CP2
chr8_+_106400322	0.776	NM_012082	ZFPM2	zinc finger protein, multitype 2
chr3_-_50624085	0.773		CISH	cytokine inducible SH2-containing protein
chr17_-_24068759	0.770	NM_001144942 NM_031934	RAB34	RAB34, member RAS oncogene family
chr3_-_50624114	0.768	NM_013324 NM_145071	CISH	cytokine inducible SH2-containing protein
chr9_+_76893232	0.767		OSTF1	osteoclast stimulating factor 1
chr16_+_30993252	0.767		ZNF646	zinc finger protein 646
chrX_+_152562013	0.762		DUSP9	dual specificity phosphatase 9
chr9_+_90339835	0.757	NM_001161625 NM_145283	NXNL2	nucleoredoxin-like 2
chr20_+_19141282	0.753	NM_020689	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr8_-_23077392	0.740	NM_003840	TNFRSF10D	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain
chr8_-_143748324	0.738		JRK	jerky homolog (mouse)
chr1_+_26479167	0.730		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr4_+_183302105	0.728		ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)
chr2_+_182030510	0.722		ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr19_+_18803786	0.720		UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)
chr9_-_132804057	0.700	NM_032843	FIBCD1	fibrinogen C domain containing 1
chr17_+_45008473	0.690		NXPH3	neurexophilin 3
chr11_+_15093059	0.680	NM_001042536	INSC	inscuteable homolog (Drosophila)
chr16_-_30993004	0.674	NM_024706	ZNF668	zinc finger protein 668
chr6_-_110607857	0.672	NM_001024934 NM_001024935 NM_001024936 NM_003931	WASF1	WAS protein family, member 1
chr8_-_143748391	0.670	NM_001077527 NM_003724	JRK	jerky homolog (mouse)
chr1_+_154878344	0.670	NM_021948 NM_198427	BCAN	brevican
chr6_+_53038181	0.658	NM_033480	FBXO9	F-box protein 9
chr12_+_52653176	0.650	NM_014212	HOXC11	homeobox C11
chr13_-_39075355	0.649	NM_005780	LHFP	lipoma HMGIC fusion partner
chr16_+_30993223	0.642	NM_014699	ZNF646	zinc finger protein 646
chr19_+_12966970	0.641	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr17_+_55854636	0.641	NM_181707	C17orf64	chromosome 17 open reading frame 64
chrX_-_151996613	0.640	NM_032882	PNMA6A	paraneoplastic antigen like 6A
chrX_+_118486390	0.638	NM_001152	SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr9_+_111442888	0.638	NM_001037293	PALM2	paralemmin 2
chrX_+_118486419	0.636		SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr10_-_5971787	0.636	NM_001009941 NM_001009943 NM_019046	ANKRD16	ankyrin repeat domain 16
chr8_+_123863224	0.632		ZHX2	zinc fingers and homeoboxes 2
chr16_-_342399	0.627	NM_003502 NM_181050	AXIN1	axin 1
chr15_-_35177664	0.623	NM_172315	MEIS2	Meis homeobox 2
chr2_-_97016027	0.621	NM_001122646	FAM178B	family with sequence similarity 178, member B
chr5_-_138758783	0.621	NM_001161546	LOC389333	hypothetical protein LOC389333
chr12_+_52696908	0.620	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr1_-_20860443	0.618		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr1_-_20860483	0.618		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr15_+_68971835	0.617	NM_001199017 NM_017691 NM_001199018	LRRC49	leucine rich repeat containing 49
chr16_-_30992574	0.615		ZNF668	zinc finger protein 668
chr7_-_5535349	0.614		ACTB	actin, beta
chr9_-_132803809	0.613		FIBCD1	fibrinogen C domain containing 1
chr7_-_5535726	0.613		ACTB	actin, beta
chr5_-_142763418	0.610	NM_000176 NM_001020825 NM_001024094	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_-_20860524	0.609		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr1_-_20860468	0.608		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr19_-_63565890	0.607	NM_198458	ZNF497	zinc finger protein 497
chr17_+_56843893	0.605	NM_203425	C17orf82	chromosome 17 open reading frame 82
chr4_-_120767777	0.601	NM_033430	PDE5A	phosphodiesterase 5A, cGMP-specific
chr14_+_20580224	0.599	NM_032572	RNASE7	ribonuclease, RNase A family, 7
chr1_-_199613427	0.598	NM_000364 NM_001001430 NM_001001431 NM_001001432	TNNT2	troponin T type 2 (cardiac)
chr17_-_39757725	0.596	NM_001143780 NM_016016	SLC25A39	solute carrier family 25, member 39
chr3_-_170864111	0.595	NM_004991	MECOM	MDS1 and EVI1 complex locus
chr1_-_199613406	0.595		TNNT2	troponin T type 2 (cardiac)
chr1_+_154351200	0.589		LMNA	lamin A/C
chr9_+_114552871	0.589	NM_001012994	SNX30	sorting nexin family member 30
chr1_-_40009513	0.587	NM_022120	OXCT2	3-oxoacid CoA transferase 2
chr20_-_55719946	0.587	NM_199171	PMEPA1	prostate transmembrane protein, androgen induced 1
chr9_+_108665168	0.586	NM_021224	ZNF462	zinc finger protein 462
chr1_-_20860534	0.586		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr5_-_131854325	0.584	NM_002198	IRF1	interferon regulatory factor 1
chr1_+_12046020	0.579	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr1_-_12599934	0.579	NM_004753	DHRS3	dehydrogenase/reductase (SDR family) member 3
chr1_-_42274160	0.577
chr19_+_18803742	0.576	NM_002911	UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)
chr11_+_9362775	0.573		IPO7	importin 7
chr1_-_108544486	0.566	NM_013386	SLC25A24	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr1_+_202308814	0.564	NM_005686	SOX13	SRY (sex determining region Y)-box 13
chr11_+_19095215	0.561	NM_001001483 NM_019028	ZDHHC13	zinc finger, DHHC-type containing 13
chr22_-_28114568	0.560	NM_001127 NM_001166019 NM_145730	AP1B1	adaptor-related protein complex 1, beta 1 subunit
chr1_-_108544416	0.559		SLC25A24	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr13_-_39075200	0.555		LHFP	lipoma HMGIC fusion partner
chr10_-_134449467	0.552	NM_177400	NKX6-2	NK6 homeobox 2
chr1_-_20860454	0.550		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr15_+_66357092	0.546	NM_015322	FEM1B	fem-1 homolog b (C. elegans)
chr11_-_103540275	0.546		PDGFD	platelet derived growth factor D
chr12_-_109372481	0.545		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr6_-_72187168	0.543		C6orf155	chromosome 6 open reading frame 155
chr4_+_156900053	0.542		GUCY1B3	guanylate cyclase 1, soluble, beta 3
chr15_+_72695248	0.538		CLK3	CDC-like kinase 3
chr12_-_109372462	0.538		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_73388291	0.537	NM_001160130 NM_001160132 NM_001160133 NM_001160134 NM_019842	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr12_-_46438447	0.536	NM_001098532 NM_006105	RAPGEF3	Rap guanine nucleotide exchange factor (GEF) 3
chr1_+_168899936	0.536	NM_006902 NM_022716	PRRX1	paired related homeobox 1
chr11_+_9362699	0.534	NM_006391	IPO7	importin 7
chr4_+_6627816	0.533		MAN2B2	mannosidase, alpha, class 2B, member 2
chr11_-_64266916	0.532
chr2_+_149895274	0.532	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr19_+_10843369	0.531		CARM1	coactivator-associated arginine methyltransferase 1
chr10_+_52504239	0.528	NM_006258	PRKG1	protein kinase, cGMP-dependent, type I
chr2_-_27147995	0.522	NM_001134693	OST4	oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr3_-_53055078	0.521	NM_001005158 NM_016329	SFMBT1	Scm-like with four mbt domains 1
chr11_-_62363551	0.521		WDR74	WD repeat domain 74
chr11_-_64267037	0.520		RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr4_+_184663141	0.519	NM_001564	ING2	inhibitor of growth family, member 2
chr17_-_39619549	0.515		C17orf65	chromosome 17 open reading frame 65
chr7_+_150387578	0.514	NM_003040	SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr11_-_9292581	0.514		TMEM41B	transmembrane protein 41B
chr17_+_45008175	0.513	NM_007225	NXPH3	neurexophilin 3
chr1_-_20860500	0.513		DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase
chr14_+_103674812	0.512	NM_015656	KIF26A	kinesin family member 26A
chr3_-_124650081	0.511	NM_183357	ADCY5	adenylate cyclase 5
chr2_-_201082978	0.508	NM_152387	KCTD18	potassium channel tetramerisation domain containing 18
chr11_-_63749916	0.508	NM_001160393	TRPT1	tRNA phosphotransferase 1
chr16_+_3447957	0.507	NM_001083600 NM_024845	NAT15	N-acetyltransferase 15 (GCN5-related, putative)
chr1_-_118529303	0.506	NM_206996	SPAG17	sperm associated antigen 17
chr14_+_55654900	0.506		PELI2	pellino homolog 2 (Drosophila)
chr4_-_122063118	0.504	NM_018699	PRDM5	PR domain containing 5
chr11_-_6451561	0.504	NM_006458 NM_033278	TRIM3	tripartite motif containing 3
chr9_-_131845277	0.502	NM_015033	FNBP1	formin binding protein 1
chr6_+_137185376	0.501	NM_000288	PEX7	peroxisomal biogenesis factor 7
chr19_-_54646837	0.500	NM_017916	PIH1D1	PIH1 domain containing 1
chr8_+_22513043	0.499	NM_001013842 NM_001198827 NM_173686	C8orf58	chromosome 8 open reading frame 58
chr7_-_134506070	0.499	NM_024033	C7orf49	chromosome 7 open reading frame 49
chr1_+_44230011	0.499		CCDC24	coiled-coil domain containing 24
chr11_-_103540233	0.499	NM_025208 NM_033135	PDGFD	platelet derived growth factor D
chr11_+_64635870	0.496	NM_003273	TM7SF2	transmembrane 7 superfamily member 2
chr12_-_109372489	0.496		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr22_-_49025499	0.494	NM_020461	TUBGCP6	tubulin, gamma complex associated protein 6
chr9_-_76757555	0.491	NM_017998	C9orf40	chromosome 9 open reading frame 40
chr1_+_26479208	0.487		SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3
chr6_+_137185441	0.487		PEX7	peroxisomal biogenesis factor 7
chr8_+_121206478	0.485	NM_021110	COL14A1	collagen, type XIV, alpha 1
chr3_+_44729138	0.484	NM_001134440 NM_001134441 NM_001134442 NM_033210	ZNF502	zinc finger protein 502
chr16_+_639278	0.482	NM_145294	WDR90	WD repeat domain 90
chr1_+_26671488	0.482	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr15_+_97010219	0.482	NM_000875	IGF1R	insulin-like growth factor 1 receptor
chr10_-_134605978	0.481	NM_173572	C10orf93	chromosome 10 open reading frame 93
chr22_+_23753940	0.481	NM_001145206	KIAA1671	KIAA1671
chr12_-_109372517	0.481		ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa
chr17_-_39757660	0.477		SLC25A39	solute carrier family 25, member 39
chr17_+_35075124	0.477	NM_003673	TCAP	titin-cap (telethonin)
chr1_+_6537924	0.474	NM_138697 NM_177540	TAS1R1	taste receptor, type 1, member 1
chr22_-_43987010	0.474	NM_015264	KIAA0930	KIAA0930
chr12_-_55920741	0.472	NM_020142	NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr1_+_152014391	0.470	NM_024330	SLC27A3	solute carrier family 27 (fatty acid transporter), member 3
chr11_-_64247230	0.470	NM_015080 NM_138732	NRXN2	neurexin 2
chr16_+_84204424	0.469	NM_014615	KIAA0182	KIAA0182
chr1_+_153241665	0.469	NM_015872	ZBTB7B	zinc finger and BTB domain containing 7B
chr3_-_120236118	0.469		IGSF11	immunoglobulin superfamily, member 11
chr1_+_112852892	0.466	NM_024494	WNT2B	wingless-type MMTV integration site family, member 2B
chr6_-_32184975	0.465	NM_019105	TNXB	tenascin XB
chr4_+_6627801	0.464	NM_015274	MAN2B2	mannosidase, alpha, class 2B, member 2
chr4_-_84250019	0.464	NM_001130716	PLAC8	placenta-specific 8
chr20_+_55359551	0.464	NM_003610	RAE1	RAE1 RNA export 1 homolog (S. pombe)
chrX_+_69589081	0.463		DLG3	discs, large homolog 3 (Drosophila)
chr19_-_51608665	0.462	NM_032040	CCDC8	coiled-coil domain containing 8
chr3_+_51964369	0.462	NM_080865	GPR62	G protein-coupled receptor 62
chr8_-_146023228	0.460		LOC100130027	hypothetical LOC100130027
chr10_-_76829857	0.460		ZNF503	zinc finger protein 503
chr22_-_20637188	0.460		PPM1F	protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr17_-_23721351	0.459		VTN	vitronectin
chrX_-_99551926	0.459	NM_001105243 NM_001184880 NM_020766	PCDH19	protocadherin 19
chr14_+_55654607	0.457	NM_021255	PELI2	pellino homolog 2 (Drosophila)
chrX_+_133993984	0.456	NM_001078171	FAM127A	family with sequence similarity 127, member A
chr7_-_100331417	0.456	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr10_+_44816278	0.455	NM_006963	ZNF22	zinc finger protein 22 (KOX 15)
chr1_+_179148935	0.454	NM_020950	KIAA1614	KIAA1614
chr22_+_36286350	0.454	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr20_+_55359706	0.453		RAE1	RAE1 RNA export 1 homolog (S. pombe)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	5.51e-06	GO:0009987	cellular process
1.12	3.49e-05	GO:0050794	regulation of cellular process
1.11	6.08e-05	GO:0065007	biological regulation
1.23	3.88e-04	GO:0048522	positive regulation of cellular process
1.11	4.25e-04	GO:0050789	regulation of biological process
1.53	7.86e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.21	8.69e-04	GO:0048518	positive regulation of biological process
1.15	4.21e-03	GO:0044260	cellular macromolecule metabolic process
1.17	4.59e-03	GO:0080090	regulation of primary metabolic process
1.17	6.25e-03	GO:0071840	cellular component organization or biogenesis
1.25	7.99e-03	GO:0016070	RNA metabolic process
1.42	8.90e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.17	9.16e-03	GO:0016043	cellular component organization
1.25	1.50e-02	GO:0023051	regulation of signaling
1.16	1.74e-02	GO:0060255	regulation of macromolecule metabolic process
1.16	2.13e-02	GO:0031323	regulation of cellular metabolic process
1.19	2.14e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22	2.33e-02	GO:0030154	cell differentiation
1.15	2.41e-02	GO:0019222	regulation of metabolic process
1.32	3.86e-02	GO:0032774	RNA biosynthetic process
1.21	4.45e-02	GO:0048869	cellular developmental process
1.26	4.49e-02	GO:0009966	regulation of signal transduction
1.18	4.84e-02	GO:0051171	regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	6.68e-07	GO:0044424	intracellular part
1.07	9.95e-07	GO:0005622	intracellular
1.11	2.01e-06	GO:0005737	cytoplasm
1.09	1.69e-05	GO:0043226	organelle
1.08	2.71e-05	GO:0043229	intracellular organelle
1.13	1.74e-04	GO:0005634	nucleus
1.84	4.45e-04	GO:0031252	cell leading edge
1.55	1.16e-02	GO:0015629	actin cytoskeleton
1.23	1.24e-02	GO:0005856	cytoskeleton
1.07	1.82e-02	GO:0043227	membrane-bounded organelle
1.03	1.84e-02	GO:0044464	cell part
1.03	1.92e-02	GO:0005623	cell
1.37	2.18e-02	GO:0030054	cell junction
1.07	2.28e-02	GO:0043231	intracellular membrane-bounded organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.17	3.69e-13	GO:0005515	protein binding
1.07	1.26e-06	GO:0005488	binding
1.45	1.93e-03	GO:0008092	cytoskeletal protein binding
1.30	9.90e-03	GO:0030528	transcription regulator activity
1.53	1.78e-02	GO:0003779	actin binding