Motif ID: ESR1.p2

Z-value: 0.991


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1



Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr21_-_45786709 3.560 NM_194255
 SLC19A1
solute carrier family 19 (folate transporter), member 1
chr16_+_29734785 1.810 C16orf53
chromosome 16 open reading frame 53
chr1_-_29322993 1.674 NM_001003682
 TMEM200B
transmembrane protein 200B
chr19_+_3536541 1.631 NM_133261
 GIPC3
GIPC PDZ domain containing family, member 3
chr6_-_11152340 1.553 NM_017770
 ELOVL2
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr11_-_69228286 1.490 NM_005117
 FGF19
fibroblast growth factor 19
chr19_-_14447122 1.428 PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr1_+_178466064 1.423 NM_033343
 LHX4
LIM homeobox 4
chr19_-_14447163 1.410 NM_000955
 PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr22_+_36632242 1.378 NM_033386
 MICALL1
MICAL-like 1
chr16_+_88512769 1.356 MC1R
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr2_-_200044233 1.355 NM_015265
 SATB2
SATB homeobox 2
chr1_+_3360880 1.329 NM_014448
 ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr3_+_16901455 1.327 NM_001144382
 PLCL2
phospholipase C-like 2
chr19_-_1463997 1.327 ADAMTSL5
ADAMTS-like 5
chr13_+_102249399 1.295 NM_001159596
NM_017693
 BIVM

basic, immunoglobulin-like variable motif containing

chr5_+_1061900 1.285 NM_033120
 NKD2
naked cuticle homolog 2 (Drosophila)
chr7_+_99919485 1.256 NM_173564
 C7orf51
chromosome 7 open reading frame 51
chr9_+_139202874 1.174 NM_003731
 SSNA1
Sjogren syndrome nuclear autoantigen 1
chr6_+_52334825 1.164 NM_133367
 PAQR8
progestin and adipoQ receptor family member VIII

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
4.68 4.10e-02 GO:0009394 2'-deoxyribonucleotide metabolic process
2.74 2.40e-02 GO:0009123 nucleoside monophosphate metabolic process
2.64 4.80e-02 GO:0051146 striated muscle cell differentiation
1.39 5.73e-03 GO:0035556 intracellular signal transduction
1.23 1.56e-03 GO:0023052 signaling
1.23 5.70e-03 GO:0007165 signal transduction
1.20 8.26e-03 GO:0051716 cellular response to stimulus
1.13 1.25e-02 GO:0050794 regulation of cellular process
1.12 2.11e-02 GO:0065007 biological regulation
1.09 1.84e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.64 4.23e-02 GO:0048471 perinuclear region of cytoplasm
1.26 1.56e-02 GO:0005829 cytosol
1.15 4.08e-07 GO:0005737 cytoplasm
1.14 9.13e-03 GO:0044444 cytoplasmic part
1.08 4.15e-03 GO:0044424 intracellular part
1.07 6.81e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.52 1.83e-02 GO:0004672 protein kinase activity
1.51 5.72e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.46 1.37e-02 GO:0016301 kinase activity
1.19 2.69e-09 GO:0005515 protein binding
1.09 4.57e-06 GO:0005488 binding